Published in Brief Bioinform on April 19, 2012
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N6-methyladenosine marks primary microRNAs for processing. Nature (2015) 1.58
Nitrogen stress response and stringent response are coupled in Escherichia coli. Nat Commun (2014) 1.57
Novel recurrently mutated genes in African American colon cancers. Proc Natl Acad Sci U S A (2015) 1.57
Widespread Inducible Transcription Downstream of Human Genes. Mol Cell (2015) 1.56
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy. Pigment Cell Melanoma Res (2013) 1.56
Tracking Distinct RNA Populations Using Efficient and Reversible Covalent Chemistry. Mol Cell (2015) 1.56
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13. Ophthalmology (2015) 1.55
The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome Biol (2013) 1.54
Assessing the necessity of confirmatory testing for exome-sequencing results in a clinical molecular diagnostic laboratory. Genet Med (2014) 1.52
Exome sequencing and complex disease: practical aspects of rare variant association studies. Hum Mol Genet (2012) 1.52
Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements. PLoS Genet (2016) 1.50
Special features of RAD Sequencing data: implications for genotyping. Mol Ecol (2012) 1.50
Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. PLoS Genet (2015) 1.49
Tumor Evolution in Two Patients with Basal-like Breast Cancer: A Retrospective Genomics Study of Multiple Metastases. PLoS Med (2016) 1.48
DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma. Mod Pathol (2014) 1.48
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Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants. Proc Natl Acad Sci U S A (2015) 1.43
APOL1 variants and kidney disease in people of recent African ancestry. Nat Rev Nephrol (2013) 1.43
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Two Independent Mutations in ADAMTS17 Are Associated with Primary Open Angle Glaucoma in the Basset Hound and Basset Fauve de Bretagne Breeds of Dog. PLoS One (2015) 1.41
NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis. J Invest Dermatol (2014) 1.40
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Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells. BMC Genomics (2015) 1.38
Accurate Breakpoint Mapping in Apparently Balanced Translocation Families with Discordant Phenotypes Using Whole Genome Mate-Pair Sequencing. PLoS One (2017) 1.37
Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature (2014) 1.36
An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. Cell Rep (2013) 1.35
Divergent Viruses Discovered in Arthropods and Vertebrates Revise the Evolutionary History of the Flaviviridae and Related Viruses. J Virol (2015) 1.35
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Methane-fed microbial microcosms show differential community dynamics and pinpoint taxa involved in communal response. ISME J (2014) 1.33
Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia. Cancer Genet (2015) 1.31
Integrated analysis of germline and somatic variants in ovarian cancer. Nat Commun (2014) 1.31
Dissecting vancomycin-intermediate resistance in staphylococcus aureus using genome-wide association. Genome Biol Evol (2014) 1.31
Assessing the performance of the Oxford Nanopore Technologies MinION. Biomol Detect Quantif (2015) 1.30
DNA copy number analysis of fresh and formalin-fixed specimens by shallow whole-genome sequencing with identification and exclusion of problematic regions in the genome assembly. Genome Res (2014) 1.28
The Genome Database for Rosaceae (GDR): year 10 update. Nucleic Acids Res (2013) 1.28
De Novo mutations in GNAO1, encoding a Gαo subunit of heterotrimeric G proteins, cause epileptic encephalopathy. Am J Hum Genet (2013) 1.27
Estimate of the spontaneous mutation rate in Chlamydomonas reinhardtii. Genetics (2012) 1.27
Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors. Clin Cancer Res (2014) 1.27
A 26-hour system of highly sensitive whole genome sequencing for emergency management of genetic diseases. Genome Med (2015) 1.26
Whole-genome sequencing of the Akata and Mutu Epstein-Barr virus strains. J Virol (2012) 1.26
Target analysis by integration of transcriptome and ChIP-seq data with BETA. Nat Protoc (2013) 1.24
Unfixed endogenous retroviral insertions in the human population. J Virol (2014) 1.23
Genome Modeling System: A Knowledge Management Platform for Genomics. PLoS Comput Biol (2015) 1.21
Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences. Oncogene (2014) 1.20
Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas. PLoS One (2013) 1.19
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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 39.09
The ENCODE (ENCyclopedia Of DNA Elements) Project. Science (2004) 38.24
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature (2009) 35.48
The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88
The variant call format and VCFtools. Bioinformatics (2011) 25.88
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BigWig and BigBed: enabling browsing of large distributed datasets. Bioinformatics (2010) 9.11
Savant: genome browser for high-throughput sequencing data. Bioinformatics (2010) 6.51
Tabix: fast retrieval of sequence features from generic TAB-delimited files. Bioinformatics (2011) 5.86
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet (2011) 5.70
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PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 39.09
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature (2012) 31.78
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ARACHNE: a whole-genome shotgun assembler. Genome Res (2002) 22.72
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Whole-genome sequence assembly for mammalian genomes: Arachne 2. Genome Res (2003) 12.30
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature (2009) 11.46
Metagenes and molecular pattern discovery using matrix factorization. Proc Natl Acad Sci U S A (2004) 10.47
Molecular signatures database (MSigDB) 3.0. Bioinformatics (2011) 8.08
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Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet (2007) 5.99
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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature (2012) 5.23
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Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest (2012) 3.64
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