Published in Front Immunol on January 03, 2012
HLA-F and MHC-I open conformers cooperate in a MHC-I antigen cross-presentation pathway. J Immunol (2013) 0.92
Dendritic cell-based vaccines: barriers and opportunities. Future Oncol (2012) 0.91
Macropinocytosis in phagocytes: regulation of MHC class-II-restricted antigen presentation in dendritic cells. Front Physiol (2015) 0.91
The effect of proteasome inhibition on the generation of the human leukocyte antigen (HLA) peptidome. Mol Cell Proteomics (2013) 0.89
Cross-presentation of IgG-containing immune complexes. Cell Mol Life Sci (2012) 0.83
IgE/FcεRI-Mediated Antigen Cross-Presentation by Dendritic Cells Enhances Anti-Tumor Immune Responses. Cell Rep (2015) 0.80
Bee Venom Phospholipase A2, a Good "Chauffeur" for Delivering Tumor Antigen to the MHC I and MHC II Peptide-Loading Compartments of the Dendritic Cells: The Case of NY-ESO-1. PLoS One (2013) 0.78
Molecular and cell-biological mechanisms of antigen cross-presentation. Front Immunol (2013) 0.78
Ex vivo nicotine stimulation augments the efficacy of human peripheral blood mononuclear cell-derived dendritic cell vaccination via activating Akt-S6 pathway. Anal Cell Pathol (Amst) (2015) 0.77
N-glycosylation converts non-glycoproteins into mannose receptor ligands and reveals antigen-specific T cell responses in vivo. Oncotarget (2016) 0.75
Dendritic cells: specialized and regulated antigen processing machines. Cell (2001) 10.44
X-ray structure of a protein-conducting channel. Nature (2003) 9.20
Differential antigen processing by dendritic cell subsets in vivo. Science (2007) 8.42
TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol (2004) 8.06
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature (1996) 7.90
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol (2008) 7.87
Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science (2008) 7.87
CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo. J Exp Med (2000) 7.46
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science (1994) 6.73
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature (2004) 6.37
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J Exp Med (1976) 6.33
The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat Immunol (2006) 5.83
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature (1997) 5.80
A membrane protein required for dislocation of misfolded proteins from the ER. Nature (2004) 5.39
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med (1996) 5.21
The vacuolar (H+)-ATPases--nature's most versatile proton pumps. Nat Rev Mol Cell Biol (2002) 5.19
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature (2008) 5.15
In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination. J Exp Med (2004) 5.07
A phagosome-to-cytosol pathway for exogenous antigens presented on MHC class I molecules. Science (1995) 4.64
Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J Exp Med (2003) 4.64
Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. Nat Cell Biol (1999) 4.53
Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell (2002) 4.52
Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress. Cell (2010) 4.45
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J Cell Biol (2003) 4.35
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature (2003) 4.18
Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med (2010) 4.17
Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen. Nature (1999) 4.13
Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate. Science (2005) 4.12
Phagosomes are competent organelles for antigen cross-presentation. Nature (2003) 3.97
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.84
Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J Exp Med (1999) 3.64
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells. J Exp Med (2010) 3.43
Distinct pathways of antigen uptake and intracellular routing in CD4 and CD8 T cell activation. Science (2007) 3.27
Activation of lysosomal function during dendritic cell maturation. Science (2003) 3.22
The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8alpha+ dendritic cells. J Exp Med (2010) 3.20
The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture. Proc Natl Acad Sci U S A (2006) 3.19
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation. Nat Immunol (2008) 3.08
Cutting edge: intravenous soluble antigen is presented to CD4 T cells by CD8- dendritic cells, but cross-presented to CD8 T cells by CD8+ dendritic cells. J Immunol (2001) 3.05
Cross-presentation by intercellular peptide transfer through gap junctions. Nature (2005) 3.03
A role for the endoplasmic reticulum protein retrotranslocation machinery during crosspresentation by dendritic cells. Immunity (2006) 3.00
Cross-presentation: underlying mechanisms and role in immune surveillance. Immunol Rev (2005) 2.98
Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages. Blood (2004) 2.84
Cross-presentation in viral immunity and self-tolerance. Nat Rev Immunol (2001) 2.76
Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection. Nature (2011) 2.75
Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm. Proc Natl Acad Sci U S A (2002) 2.68
NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells. Blood (2008) 2.54
CD8+ T cell cross-priming via transfer of proteasome substrates. Science (2004) 2.51
Quantitative and dynamic assessment of the contribution of the ER to phagosome formation. Cell (2005) 2.35
Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity. Sci Transl Med (2010) 2.32
Proteasome and peptidase function in MHC-class-I-mediated antigen presentation. Curr Opin Immunol (2004) 2.27
Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells. Eur J Immunol (1997) 2.25
Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo. Immunity (2004) 2.13
The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane. Cell (1997) 2.09
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A (2003) 2.09
Antigenic targeting of the human mannose receptor induces tumor immunity. J Immunol (2007) 1.93
Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity (2003) 1.89
In vivo cross-priming of MHC class I-restricted antigens requires the TAP transporter. Immunity (1996) 1.89
Antigen bias in T cell cross-priming. Science (2004) 1.82
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells. Immunity (2009) 1.82
Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes. J Immunol (2010) 1.78
Bacteria-induced neo-biosynthesis, stabilization, and surface expression of functional class I molecules in mouse dendritic cells. Proc Natl Acad Sci U S A (1998) 1.74
Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules. Proc Natl Acad Sci U S A (2010) 1.70
The cell biology of cross-presentation and the role of dendritic cell subsets. Immunol Cell Biol (2008) 1.69
Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood (2005) 1.57
Dendritic cells cross-dressed with peptide MHC class I complexes prime CD8+ T cells. J Immunol (2006) 1.53
The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells. Immunity (2009) 1.53
Antigen presentation to CD8+ T cells: cross-priming in infectious diseases. Curr Opin Immunol (2001) 1.53
Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent. Am J Physiol Gastrointest Liver Physiol (2002) 1.47
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells. Proc Natl Acad Sci U S A (2011) 1.44
IRAP identifies an endosomal compartment required for MHC class I cross-presentation. Science (2009) 1.43
Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. J Exp Med (2009) 1.42
Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel. Immunity (2000) 1.41
Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action. Proc Natl Acad Sci U S A (2010) 1.25
Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A (2009) 1.24
Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells. Int Immunol (2004) 1.24
Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo. J Immunol (2006) 1.22
Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur J Immunol (1999) 1.20
Roles of proteasomes, transporter for antigen presentation (TAP), and beta 2-microglobulin in the processing of bacterial or particulate antigens via an alternate class I MHC processing pathway. J Immunol (1996) 1.17
hDectin-1 is involved in uptake and cross-presentation of cellular antigens. Blood (2007) 1.13
The relative efficiency of acquisition of MHC:peptide complexes and cross-presentation depends on dendritic cell type. J Immunol (2008) 1.11
A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells. Traffic (2011) 1.10
Control of cross-presentation during dendritic cell maturation. Eur J Immunol (2004) 1.08
Targeting DC-SIGN via its neck region leads to prolonged antigen residence in early endosomes, delayed lysosomal degradation, and cross-presentation. Blood (2011) 1.06
Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1. J Immunol (2010) 1.05
Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation. Proc Natl Acad Sci U S A (2011) 1.05
Mannose receptor expression and function define a new population of murine dendritic cells. J Immunol (2007) 1.05
Role of immunoproteasomes in cross-presentation. J Immunol (2006) 1.05
Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells. Proc Natl Acad Sci U S A (2009) 1.05
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Int J Biochem Cell Biol (2008) 1.04
Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells. EMBO J (2007) 1.02
Functional gap junctions facilitate melanoma antigen transfer and cross-presentation between human dendritic cells. J Immunol (2007) 1.01
Molecular machinations of the MHC-I peptide loading complex. Curr Opin Immunol (2008) 0.98
The delivery of an antigen from the endocytic compartment into the cytosol for cross-presentation is restricted to early immature dendritic cells. Immunology (2006) 0.96
Mannose receptor-dependent delay in phagosome maturation by Mycobacterium avium glycopeptidolipids. Infect Immun (2009) 0.93
A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes. Proc Natl Acad Sci U S A (2007) 0.92
A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment. J Biol Chem (2006) 0.91
Involvement of mannose receptor in glycopeptidolipid-mediated inhibition of phagosome-lysosome fusion. Microbiol Immunol (2006) 0.91
CD8- dendritic cells preferentially cross-present Saccharomyces cerevisiae antigens. Eur J Immunol (2008) 0.91
The functional half-life of H-2Kd-restricted T cell epitopes on living cells. Eur J Immunol (1996) 0.87
The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med (2009) 1.95
Dynamic regulation of CD8 T cell tolerance induction by liver sinusoidal endothelial cells. J Immunol (2010) 1.59
Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor. J Exp Med (2012) 1.32
M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. J Cell Biol (2013) 1.19
The kidney-renal lymph node-system contributes to cross-tolerance against innocuous circulating antigen. J Immunol (2008) 1.12
The non-phagocytic route of collagen uptake: a distinct degradation pathway. J Biol Chem (2011) 1.09
Mannose receptor polyubiquitination regulates endosomal recruitment of p97 and cytosolic antigen translocation for cross-presentation. Proc Natl Acad Sci U S A (2011) 1.05
Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: role of macrophage scavenger receptor class A type I and II. J Allergy Clin Immunol (2009) 1.05
Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol (2009) 0.97
The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J Immunol (2011) 0.92
Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology (2009) 0.90
Design of neo-glycoconjugates that target the mannose receptor and enhance TLR-independent cross-presentation and Th1 polarization. Eur J Immunol (2011) 0.90
Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J (2011) 0.89
Steady-state cross-presentation of OVA is mannose receptor-dependent but inhibitable by collagen fragments. Proc Natl Acad Sci U S A (2010) 0.87
Characterization of rat BLOS2/Ceap, a putative yeast She3 homolog, as interaction partner of apoptosis antagonizing transcription factor/Che-1. Biol Chem (2007) 0.86
The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. Basic Res Cardiol (2014) 0.85
Nurse-like cells show deregulated expression of genes involved in immunocompetence. Br J Haematol (2011) 0.84
Impact of culture medium on maturation of bone marrow-derived murine dendritic cells via the aryl hydrocarbon receptor. Mol Immunol (2012) 0.82
Regulation of antigen transport into the cytosol for cross-presentation by ubiquitination of the mannose receptor. Mol Immunol (2012) 0.79
Intraendosomal flow cytometry: a novel approach to analyze the protein composition of antigen-loaded endosomes. Eur J Immunol (2012) 0.77
Isolation of a specialized, antigen-loaded early endosomal subpopulation by flow cytometry. Methods Mol Biol (2013) 0.77
Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity. J Biol Chem (2014) 0.76
TAP mediates import of Mycobacterium tuberculosis-derived peptides into phagosomes and facilitates loading onto HLA-I. PLoS One (2013) 0.76
Monitoring the intracellular routing of internalized antigens by immunofluorescence microscopy. Methods Mol Biol (2013) 0.75