Nox2 is a mediator of chronic CsA nephrotoxicity.

Tubular expression of heat-shock protein 27 inhibits fibrogenesis in obstructive nephropathy. Kidney Int (2012) 1.50

Role of NADPH oxidase-mediated reactive oxygen species in podocyte injury. Biomed Res Int (2013) 0.92

Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis. BMC Nephrol (2013) 0.91

The role of complement in the pathogenesis of renal ischemia-reperfusion injury and fibrosis. Fibrogenesis Tissue Repair (2014) 0.86

Calcineurin Aβ regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose. J Biol Chem (2013) 0.81

Nox2 Is a Mediator of Ischemia Reperfusion Injury. Am J Transplant (2015) 0.80

Characterization of transfusion-elicited acute antibody-mediated rejection in a rat model of kidney transplantation. Am J Transplant (2014) 0.80

NADPH Oxidase-2 Mediates Zinc Deficiency-Induced Oxidative Stress and Kidney Damage. Am J Physiol Cell Physiol (2016) 0.75

Increased Advanced Oxidation Protein Products Generation by Cyclosporine-A and Angiotensin II in Human Gingival Fibroblasts - Ex-vivo Study. J Clin Diagn Res (2017) 0.75

Nox2 and Cyclosporine-Induced Renal Hypoxia. Transplantation (2016) 0.75

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev (2007) 21.13

TGF-beta and epithelial-to-mesenchymal transitions. Oncogene (2005) 10.02

The natural history of chronic allograft nephropathy. N Engl J Med (2003) 8.70

Chronic renal failure after transplantation of a nonrenal organ. N Engl J Med (2003) 8.47

Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production. Nat Genet (1995) 7.34

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant. Hypertension (2007) 5.80

New insights into epithelial-mesenchymal transition in kidney fibrosis. J Am Soc Nephrol (2009) 3.83

Mechanisms of tubulointerstitial fibrosis. J Am Soc Nephrol (2010) 3.75

The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction. Mol Cell Biol (2004) 3.35

Calcineurin inhibitor nephrotoxicity. Clin J Am Soc Nephrol (2009) 3.33

Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant (2010) 3.29

NADPH oxidases in the kidney. Antioxid Redox Signal (2006) 2.70

Evidence for antibody-mediated injury as a major determinant of late kidney allograft failure. Transplantation (2010) 2.59

Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Mol Cell Biol (2006) 2.12

Review of imaging solutions for integrated quantitative immunohistochemistry in the Pathology daily practice. Folia Histochem Cytobiol (2009) 1.79

Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. Kidney Int (2003) 1.61

Primer: Histopathology of calcineurin-inhibitor toxicity in renal allografts. Nat Clin Pract Nephrol (2006) 1.47

Structural insights into Nox4 and Nox2: motifs involved in function and cellular localization. Mol Cell Biol (2009) 1.41

Classical inhibitors of NOX NAD(P)H oxidases are not specific. Curr Drug Metab (2008) 1.39

Oxidative stress as a common pathway to chronic tubulointerstitial injury in kidney allografts. Am J Physiol Renal Physiol (2007) 1.33

Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. Curr Opin Crit Care (2001) 1.32

Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity. Clin Transplant (2008) 1.29

Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition. Am J Pathol (2005) 1.28

Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells. Nephrol Dial Transplant (2005) 1.25

Spectral imaging perspective on cytomics. Cytometry A (2006) 1.23

Cyclosporine nephrotoxicity. Semin Nephrol (2003) 1.18

HSP27 is involved in the pathogenesis of kidney tubulointerstitial fibrosis. Am J Physiol Renal Physiol (2008) 1.11

Nox-2 is a modulator of fibrogenesis in kidney allografts. Am J Transplant (2008) 1.11

Cyclosporine A induces senescence in renal tubular epithelial cells. Am J Physiol Renal Physiol (2007) 1.08

Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506. J Immunol (2008) 1.03

Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E. Kidney Int (1995) 1.03

Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone. Transplantation (2007) 1.02

Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase. Hypertension (2004) 1.00

Transforming growth factor (TGF)-beta mimics and anti-TGF-beta antibody abrogates the in vivo effects of cyclosporine: demonstration of a direct role of TGF-beta in immunosuppression and nephrotoxicity of cyclosporine. Transplantation (1999) 0.98

Up-regulation of kidney NAD(P)H oxidase and calcineurin in SHR: reversal by lifelong antioxidant supplementation. Kidney Int (2004) 0.95

Mycophenolic acid may delay allograft fibrosis by inhibiting transforming growth factor-beta1-induced activation of Nox-2 through the nuclear factor-kappaB pathway. Transplantation (2010) 0.93

Novel immunosuppressive agents in kidney transplantation. Clin Nephrol (2010) 0.90

Fibrogenesis in kidney transplantation: potential targets for prevention and therapy. Transplantation (2009) 0.90

Reproducibility studies on arteriolar hyaline thickening scoring in calcineurin inhibitor-treated renal allograft recipients. Am J Transplant (2006) 0.88

Drug insight: maintenance immunosuppression in kidney transplant recipients. Nat Clin Pract Nephrol (2006) 0.88

Renal disease in recipients of nonrenal solid organ transplantation. Semin Nephrol (2007) 0.87

Our evolving understanding of late kidney allograft failure. Curr Opin Organ Transplant (2011) 0.85

Diverse effects of natural antioxidants on cyclosporin cytotoxicity in rat renal tubular cells. Nephrol Dial Transplant (2005) 0.84

Role of reactive oxygen formation in the cyclosporin-A-mediated impairment of renal functions. Transplant Proc (1994) 0.80

Cyclosporin A generates superoxide in smooth muscle cells. Free Radic Res (2005) 0.80

Successful renal transplantation in patients with chronic granulomatous disease. Am J Transplant (2006) 0.80

THE EFFECT OF CALCIUM ON THE ABSORPTION OF POTASSIUM BY BARLEY ROOTS. Plant Physiol (1952) 6.90

Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes. FEBS Lett (1990) 5.14

The Influence of Hydrogen Ion Concentration on Cation Absorption by Barley Roots. Plant Physiol (1954) 4.68

Electron transfer by domain movement in cytochrome bc1. Nature (1998) 4.08

Prostate cancer susceptibility locus on chromosome 1q: a confirmatory study. J Natl Cancer Inst (1997) 3.92

Objectivized diagnosis of acute pelvic inflammatory disease. Diagnostic and prognostic value of routine laparoscopy. Am J Obstet Gynecol (1969) 3.91

Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Nat Genet (2001) 3.65

Ethical consideration of incidental findings on adult brain MRI in research. Neurology (2004) 3.56

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo. Proc Natl Acad Sci U S A (2000) 3.44

Iron Transport in Pea Plants. Plant Physiol (1962) 3.27

Mutations in the gene encoding gap junction protein beta-3 associated with autosomal dominant hearing impairment. Nat Genet (1998) 3.24

Alterations of the PPP2R1B gene in human lung and colon cancer. Science (1998) 3.14

Uptake of calcium by excised barley roots. Plant Physiol (1961) 3.07

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. Blood (2001) 3.00

Reservoirs for human campylobacteriosis. J Infect Dis (1980) 2.87

Gene therapy progress and prospects: nonviral vectors. Gene Ther (2002) 2.79

A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem Biophys Res Commun (1991) 2.72

Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells. J Virol (2001) 2.69

Toxicity of ALS-linked SOD1 mutants. Science (2000) 2.69

Sensitivity and specificity of fluorescence microscopy for diagnosing pulmonary tuberculosis in a high HIV prevalence setting. Int J Tuberc Lung Dis (2009) 2.68

Rational use of in vitro P-glycoprotein assays in drug discovery. J Pharmacol Exp Ther (2001) 2.67

Inhibition of Ion Absorption and Respiration in Barley Roots. Plant Physiol (1955) 2.59

Simultaneous interview technique for patients with persistent pain. Pain (1991) 2.58

Prescription opiate abuse in chronic pain patients: clinical criteria, incidence, and predictors. Clin J Pain (1997) 2.58

Seroconversion, sexual activity, and condom use among 2915 HIV seronegative men followed for up to 2 years. J Acquir Immune Defic Syndr (1989) 2.48

Uptake of magnesium & its interaction with calcium in excised barley roots. Plant Physiol (1961) 2.39

Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc Natl Acad Sci U S A (1993) 2.35

Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt. Mol Cell Biol (1998) 2.28

Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature (1995) 2.21

Surveillance of the first case of human avian influenza A (H7N9) virus in Beijing, China. Infection (2013) 2.18

Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. J Virol (1996) 2.17

ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nat Cell Biol (2001) 2.14

Enzymatic completion of mammalian lagging-strand DNA replication. Proc Natl Acad Sci U S A (1994) 2.11

The role of dioleoyl phosphatidylethanolamine in cationic liposome mediated gene transfer. Biochim Biophys Acta (1995) 2.10

Genetic variation in Pneumocystis carinii isolates from different geographic regions: implications for transmission. Emerg Infect Dis (2000) 2.08

Proteomic analysis of nucleoporin interacting proteins. J Biol Chem (2001) 2.06

Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas. Mol Carcinog (1998) 2.06

Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains. J Neurosci (2004) 2.03

Transmembrane pH gradient and membrane potential in Clostridium acetobutylicum during growth under acetogenic and solventogenic conditions. Appl Environ Microbiol (1985) 2.02

Activity of amphipathic poly(ethylene glycol) 5000 to prolong the circulation time of liposomes depends on the liposome size and is unfavorable for immunoliposome binding to target. Biochim Biophys Acta (1991) 2.01

Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins. Mol Cell Biol (1994) 2.00

Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors. Oncogene (2007) 1.95

Crystal structure of an activated response regulator bound to its target. Nat Struct Biol (2001) 1.95

The multicenter AIDS Cohort Study, 1983 to …. Public Health (2011) 1.93

Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. Mol Biol Cell (1999) 1.91

New structures in complex formation between DNA and cationic liposomes visualized by freeze-fracture electron microscopy. FEBS Lett (1994) 1.90

Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways. Am J Respir Cell Mol Biol (2000) 1.86

Benchmark data and power calculations for evaluating disease outbreak detection methods. MMWR Morb Mortal Wkly Rep (2004) 1.86

Protamine sulfate enhances lipid-mediated gene transfer. Gene Ther (1997) 1.86

Regulation of ACTH secretion: variations on a theme of B. Recent Prog Horm Res (1987) 1.85

Gene therapy progress and prospects: non-viral gene therapy by systemic delivery. Gene Ther (2006) 1.84

Patterns of protein synthesis and tolerance of anoxia in root tips of maize seedlings acclimated to a low-oxygen environment, and identification of proteins by mass spectrometry. Plant Physiol (2000) 1.82

Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice. J Clin Invest (2000) 1.82

Aspartoacylase gene transfer to the mammalian central nervous system with therapeutic implications for Canavan disease. Ann Neurol (2000) 1.82

The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum Gene Ther (1999) 1.81

Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim Biophys Acta (1994) 1.79

A physical map of chromosome 2 of Arabidopsis thaliana. Genome Res (1996) 1.77

Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum Gene Ther (2001) 1.76

Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial. J Clin Oncol (2001) 1.73

A(2A) adenosine receptor-mediated inhibition of renal injury and neutrophil adhesion. Am J Physiol Renal Physiol (2000) 1.71

Iron Localization in Pea Plants. Plant Physiol (1962) 1.71

Cationic liposome-mediated gene transfer. Gene Ther (1995) 1.68

Nonviral gene therapy: promises and challenges. Gene Ther (2000) 1.65

Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia. J Exp Med (2000) 1.65

Normative data for a brief neuropsychological screening battery. Multicenter AIDS Cohort Study. Percept Mot Skills (1991) 1.62

Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney. Am J Physiol (1999) 1.61

Threonine phosphorylation of the MMAC1/PTEN PDZ binding domain both inhibits and stimulates PDZ binding. Cancer Res (2000) 1.60

Potentiation of cationic liposome-mediated gene delivery by polycations. Biochemistry (1996) 1.60

Hepatic resection of metastatic testicular carcinoma: a further update. Ann Surg Oncol (1999) 1.59

Reliability and interrelationships between maximal oxygen intake, physical work capacity and step-test scores in college women. Med Sci Sports (1972) 1.59

Primary structure of two distinct rat pancreatic preproelastases determined by sequence analysis of the complete cloned messenger ribonucleic acid sequences. Biochemistry (1982) 1.57

Acquired immune deficiency syndrome occurring within 5 years of infection with human immunodeficiency virus type-1: the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr (1992) 1.57

Structure and function of lipid-DNA complexes for gene delivery. Annu Rev Biophys Biomol Struct (2000) 1.57

Permanent declines in pulmonary function following pneumonia in human immunodeficiency virus-infected persons. The Pulmonary Complications of HIV Infection Study Group. Am J Respir Crit Care Med (2000) 1.56

Ion Absorption and Retention by Chlorella pyrenoidosa. I. Absorption of Potassium. Plant Physiol (1965) 1.55

Folate-targeted, anionic liposome-entrapped polylysine-condensed DNA for tumor cell-specific gene transfer. J Biol Chem (1996) 1.55

Architectural design and tools to support the transparent access to hospital information systems, radiology information systems, and picture archiving and communication systems. J Digit Imaging (1996) 1.54

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action. Biochim Biophys Acta (1994) 1.54

Recognising meningococcal disease in primary care: qualitative study of how general practitioners process clinical and contextual information. BMJ (1998) 1.54

Transcatheter closure of patent ductus arteriosus with severe pulmonary arterial hypertension in adults. Heart (2006) 1.53

Kaposi's sarcoma-associated herpesvirus K-bZIP protein is phosphorylated by cyclin-dependent kinases. J Virol (2001) 1.51

An abundant DNA binding protein from the hyperthermophilic archaeon Sulfolobus shibatae affects DNA supercoiling in a temperature-dependent fashion. J Bacteriol (2000) 1.51

In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther (1997) 1.51

Resorcylic acid lactones: naturally occurring potent and selective inhibitors of MEK. J Antibiot (Tokyo) (1999) 1.51

Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes. Biochim Biophys Acta (1992) 1.50

The calf 5'- to 3'-exonuclease is also an endonuclease with both activities dependent on primers annealed upstream of the point of cleavage. J Biol Chem (1994) 1.49

Electrical localization of spinal roots for the treatment of spasticity by intrathecal alcohol injection. Anesth Analg (1989) 1.48

Generation by insulin of a chemical mediator that controls protein phosphorylation and dephosphorylation. Science (1979) 1.48

Blood gene expression signatures predict exposure levels. Proc Natl Acad Sci U S A (2007) 1.48

Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther (1999) 1.47

Excising the reexcision: stereotactic core-needle biopsy decreases need for reexcision of breast cancer. World J Surg (1998) 1.47

Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity. J Cell Sci (2001) 1.46

An Arabidopsis mutant with a reduced level of cab140 RNA is a result of cosuppression. Plant Cell (1993) 1.45

pH-sensitive immunoliposomes mediate target-cell-specific delivery and controlled expression of a foreign gene in mouse. Proc Natl Acad Sci U S A (1987) 1.44

Nomenclature for synthetic gene delivery systems. Hum Gene Ther (1997) 1.44

beta-Catenin is essential for patterning the maternally specified animal-vegetal axis in the sea urchin embryo. Proc Natl Acad Sci U S A (1998) 1.44

The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I. Nat Struct Biol (2000) 1.41

Truncation of the carboxy-terminal 28 amino acids of glycoprotein B specified by herpes simplex virus type 1 mutant amb1511-7 causes extensive cell fusion. J Virol (1993) 1.40

Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3. Cell (2001) 1.40

Relationship between leptin and chronic inflammatory state in uremic patients. Eur Rev Med Pharmacol Sci (2014) 1.40