Combination strategies to enhance antitumor ADCC.

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Published in Immunotherapy on May 01, 2012

Authors

Holbrook E Kohrt1, Roch Houot, Aurélien Marabelle, Hearn Jay Cho, Keren Osman, Matthew Goldstein, Ronald Levy, Joshua Brody

Author Affiliations

1: Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA.

Associated clinical trials:

A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab | NCT01307267

Trial of TRX518 (Anti-GITR mAb) in Stage III or IV Malignant Melanoma or Other Solid Tumors (TRX518-001) | NCT01239134

Anti-OX40, Cyclophosphamide (CTX) and Radiation in Patients With Progressive Metastatic Prostate Cancer | NCT01303705

Isotretinoin With or Without Dinutuximab, Aldesleukin, and Sargramostim Following Stem Cell Transplant in Treating Patients With Neuroblastoma | NCT00026312

Monoclonal Antibody CT-011 in Combination With Rituximab in Patients With Relapsed Follicular Lymphoma | NCT00904722

Cetuximab and Recombinant Interleukin-12 in Treating Patients With Squamous Cell Carcinoma of the Head and Neck That is Recurrent, Metastatic, or Cannot Be Removed by Surgery | NCT01468896

Pilot hu14.18-IL2 in Resectable Recurrent Stage III or Stage IV Melanoma | NCT00590824

Fusion Protein Cytokine Therapy After Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma | NCT00720135

A Phase I Study of GNKG168 in Patient With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL) | NCT01035216

Lenalidomide and Cetuximab in Patients With Advanced Solid Tumors (TEXO) | NCT01166035

Rituximab and Autologous Effector Lymphocytes in Non-Hodgkin Follicular Lymphoma in Response to First Line Chemotherapy | NCT01329354

Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer (ADCC) | NCT01254617

Biocell Natural Killer Mixture in Diffuse Large B Cell Lymphoma (DLBCL) Patients (NKCell) | NCT00846157

Cetuximab and Lenalidomide in Head and Neck | NCT01133665

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