Published in RNA Biol on June 01, 2012
Long noncoding RNAs: cellular address codes in development and disease. Cell (2013) 6.01
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Res (2012) 5.04
The multilayered complexity of ceRNA crosstalk and competition. Nature (2014) 4.15
Long noncoding RNAs: past, present, and future. Genetics (2013) 3.16
Long noncoding RNAs and the genetics of cancer. Br J Cancer (2013) 2.98
Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer. Mol Cancer (2014) 2.70
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet (2013) 2.59
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. Hepatology (2014) 2.27
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol (2012) 1.90
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus. Cell Res (2014) 1.83
Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep (2012) 1.82
Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat Rev Drug Discov (2013) 1.82
Evolutionary conservation of long non-coding RNAs; sequence, structure, function. Biochim Biophys Acta (2013) 1.79
Concern The functional role of long non-coding RNAs and epigenetics. Biol Proced Online (2014) 1.73
Knockdown of long non-coding RNA HOTAIR suppresses tumor invasion and reverses epithelial-mesenchymal transition in gastric cancer. Int J Biol Sci (2013) 1.62
Negative regulation of lncRNA GAS5 by miR-21. Cell Death Differ (2013) 1.60
MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway. Cancer Biol Ther (2014) 1.55
LncRNA: a new player in 1α, 25(OH)(2) vitamin D(3) /VDR protection against skin cancer formation. Exp Dermatol (2014) 1.53
Long non-coding RNA in cancer. Int J Mol Sci (2013) 1.52
Long non-coding RNA H19 promotes glioma cell invasion by deriving miR-675. PLoS One (2014) 1.52
A pathophysiological view of the long non-coding RNA world. Oncotarget (2014) 1.36
Long non-coding RNA Linc00152 is involved in cell cycle arrest, apoptosis, epithelial to mesenchymal transition, cell migration and invasion in gastric cancer. Cell Cycle (2015) 1.33
Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets. Mol Cell Ther (2015) 1.32
SP1-induced upregulation of the long noncoding RNA TINCR regulates cell proliferation and apoptosis by affecting KLF2 mRNA stability in gastric cancer. Oncogene (2015) 1.28
Long noncoding RNA involvement in cancer. BMB Rep (2012) 1.28
The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer. J Transl Med (2015) 1.27
Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer. Genome Biol (2014) 1.25
The long noncoding RNA SPRY4-IT1 increases the proliferation of human breast cancer cells by upregulating ZNF703 expression. Mol Cancer (2015) 1.24
Junk DNA and the long non-coding RNA twist in cancer genetics. Oncogene (2015) 1.22
LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer. Biochim Biophys Acta (2015) 1.21
Long noncoding RNA HOTAIR is associated with motility, invasion, and metastatic potential of metastatic melanoma. Biomed Res Int (2013) 1.21
Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3. Oncotarget (2016) 1.20
Downregulation of GAS5 promotes bladder cancer cell proliferation, partly by regulating CDK6. PLoS One (2013) 1.19
Expression analysis and in silico characterization of intronic long noncoding RNAs in renal cell carcinoma: emerging functional associations. Mol Cancer (2013) 1.18
Analysing the relationship between lncRNA and protein-coding gene and the role of lncRNA as ceRNA in pulmonary fibrosis. J Cell Mol Med (2014) 1.14
The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation. PLoS Genet (2013) 1.14
Physiological roles of long noncoding RNAs: insight from knockout mice. Trends Cell Biol (2014) 1.12
Cell cycle regulation by long non-coding RNAs. Cell Mol Life Sci (2013) 1.10
Role of non-coding sequence variants in cancer. Nat Rev Genet (2016) 1.10
Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells. Int J Mol Sci (2014) 1.09
Long noncoding RNAs in cancer: mechanisms of action and technological advancements. Mol Cancer (2016) 1.08
The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population. Oncotarget (2015) 1.07
Non-coding RNAs: multi-tasking molecules in the cell. Int J Mol Sci (2013) 1.07
An emerging understanding of long noncoding RNAs in kidney cancer. J Cancer Res Clin Oncol (2014) 1.07
Long noncoding RNA HOXA-AS2 promotes gastric cancer proliferation by epigenetically silencing P21/PLK3/DDIT3 expression. Oncotarget (2015) 1.05
High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma. J Transl Med (2015) 1.05
A potential prognostic long non-coding RNA signature to predict metastasis-free survival of breast cancer patients. Sci Rep (2015) 1.04
lncRNA GAS5 enhances G1 cell cycle arrest via binding to YBX1 to regulate p21 expression in stomach cancer. Sci Rep (2015) 1.04
Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA. Sci Rep (2015) 1.04
Long Non Coding RNA MALAT1 Promotes Tumor Growth and Metastasis by inducing Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma. Sci Rep (2015) 1.03
Long non-coding RNA PVT1 is associated with tumor progression and predicts recurrence in hepatocellular carcinoma patients. Oncol Lett (2014) 1.03
The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. Nat Cell Biol (2016) 1.02
LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2. PLoS One (2014) 1.02
lncRNome: a comprehensive knowledgebase of human long noncoding RNAs. Database (Oxford) (2013) 1.02
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity. Genome Med (2014) 1.02
Urothelial cancer associated 1: a long noncoding RNA with a crucial role in cancer. J Cancer Res Clin Oncol (2015) 1.01
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia. Leukemia (2015) 1.01
Pivots of pluripotency: the roles of non-coding RNA in regulating embryonic and induced pluripotent stem cells. Biochim Biophys Acta (2012) 1.00
Involvement of extracellular vesicle long noncoding RNA (linc-VLDLR) in tumor cell responses to chemotherapy. Mol Cancer Res (2014) 0.99
Upregulated lncRNA-UCA1 contributes to progression of lung cancer and is closely related to clinical diagnosis as a predictive biomarker in plasma. Int J Clin Exp Med (2015) 0.99
Association of long non-coding RNA HOTTIP with progression and prognosis in colorectal cancer. Int J Clin Exp Pathol (2015) 0.98
Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma. BMC Cancer (2015) 0.98
Long non-coding RNAs (lncRNAs) and viral infections. Biomed Pharmacother (2013) 0.98
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease. Endocr Rev (2014) 0.98
Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds. Mol Cancer (2013) 0.96
Large intervening non-coding RNA HOTAIR is an indicator of poor prognosis and a therapeutic target in human cancers. Int J Mol Sci (2014) 0.96
LncRNA2Target: a database for differentially expressed genes after lncRNA knockdown or overexpression. Nucleic Acids Res (2014) 0.96
Long non-coding RNAs and their implications in cancer epigenetics. Biosci Rep (2013) 0.95
Constructing lncRNA functional similarity network based on lncRNA-disease associations and disease semantic similarity. Sci Rep (2015) 0.95
Long non-coding RNA HULC as a novel serum biomarker for diagnosis and prognosis prediction of gastric cancer. Oncotarget (2016) 0.95
Tumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling. Cell Death Dis (2016) 0.94
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia. Haematologica (2014) 0.94
Long noncoding RNA plays a key role in metastasis and prognosis of hepatocellular carcinoma. Biomed Res Int (2014) 0.94
The long non-coding RNA ERIC is regulated by E2F and modulates the cellular response to DNA damage. Mol Cancer (2013) 0.93
Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes. Cell Death Dis (2015) 0.93
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts. Nucleic Acids Res (2015) 0.93
The fusion of two worlds: non-coding RNAs and extracellular vesicles--diagnostic and therapeutic implications (Review). Int J Oncol (2014) 0.93
Long non-coding RNA Loc554202 induces apoptosis in colorectal cancer cells via the caspase cleavage cascades. J Exp Clin Cancer Res (2015) 0.93
Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes. PLoS One (2014) 0.92
Long non-coding RNAs in colorectal cancer. Oncotarget (2016) 0.92
The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching. J Invest Dermatol (2015) 0.92
Regulatory Roles for Long ncRNA and mRNA. Cancers (Basel) (2013) 0.92
Noncoding RNAs in cancer and cancer stem cells. Chin J Cancer (2013) 0.92
Antisense Long Noncoding RNA HIF1A-AS2 Is Upregulated in Gastric Cancer and Associated with Poor Prognosis. Dig Dis Sci (2015) 0.92
Upregulation of long non-coding RNA urothelial carcinoma associated 1 by CCAAT/enhancer binding protein α contributes to bladder cancer cell growth and reduced apoptosis. Oncol Rep (2014) 0.92
Prognostic impact of HOTAIR expression is restricted to ER-negative breast cancers. Sci Rep (2015) 0.92
Long non-coding RNAs in cancer and development: where do we go from here? Int J Mol Sci (2015) 0.92
Long non-coding RNAs in gastric cancer: versatile mechanisms and potential for clinical translation. Am J Cancer Res (2015) 0.92
The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations. EMBO Mol Med (2016) 0.91
Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer. Genomics Proteomics Bioinformatics (2016) 0.91
Regulation of apoptosis by long non-coding RNA HIF1A-AS1 in VSMCs: implications for TAA pathogenesis. Int J Clin Exp Pathol (2014) 0.90
Differentially expressed transcripts and dysregulated signaling pathways and networks in African American breast cancer. PLoS One (2013) 0.90
Role of MALAT1 as a Prognostic Factor for Survival in Various Cancers: A Systematic Review of the Literature with Meta-Analysis. Dis Markers (2015) 0.90
The non-coding transcriptome as a dynamic regulator of cancer metastasis. Cancer Metastasis Rev (2014) 0.89
Transforming growth factor-β-induced lncRNA-Smad7 inhibits apoptosis of mouse breast cancer JygMC(A) cells. Cancer Sci (2014) 0.89
The non-coding RNAs of the H19-IGF2 imprinted loci: a focus on biological roles and therapeutic potential in Lung Cancer. J Transl Med (2015) 0.89
Combined identification of long non-coding RNA XIST and HIF1A-AS1 in serum as an effective screening for non-small cell lung cancer. Int J Clin Exp Pathol (2015) 0.89
Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy. J Biol Chem (2014) 0.88
MicroRNAs and liver cancer associated with iron overload: therapeutic targets unravelled. World J Gastroenterol (2013) 0.88
Long noncoding RNAs in diseases of aging. Biochim Biophys Acta (2015) 0.88
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Hallmarks of cancer: the next generation. Cell (2011) 140.01
The hallmarks of cancer. Cell (2000) 113.05
Cancer statistics, 2010. CA Cancer J Clin (2010) 103.28
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer (2010) 90.16
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
MicroRNA signatures in human cancers. Nat Rev Cancer (2006) 46.29
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature (2009) 35.48
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
p53 mutations in human cancers. Science (1991) 31.96
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79
Immunity, inflammation, and cancer. Cell (2010) 28.27
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell (1996) 23.99
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer (2003) 22.78
Upstream and downstream of mTOR. Genes Dev (2004) 21.61
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A (2009) 20.66
Long non-coding RNAs: insights into functions. Nat Rev Genet (2009) 19.61
Fibroblasts in cancer. Nat Rev Cancer (2006) 18.95
RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science (2007) 18.59
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer (2009) 18.53
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell (2010) 17.87
Global identification of human transcribed sequences with genome tiling arrays. Science (2004) 17.85
Evolution and functions of long noncoding RNAs. Cell (2009) 17.54
Ultraconserved elements in the human genome. Science (2004) 17.14
Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Science (2005) 16.82
Microenvironmental regulation of metastasis. Nat Rev Cancer (2008) 15.76
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
Autophagy: process and function. Genes Dev (2007) 15.21
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature (2010) 13.82
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Macrophage diversity enhances tumor progression and metastasis. Cell (2010) 13.41
Matrix metalloproteinases: regulators of the tumor microenvironment. Cell (2010) 12.90
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol (2009) 11.50
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J (1992) 10.97
A survey of telomerase activity in human cancer. Eur J Cancer (1997) 10.84
The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene (2007) 10.08
The RNA component of human telomerase. Science (1995) 9.86
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science (2005) 9.25
Long noncoding RNAs: functional surprises from the RNA world. Genes Dev (2009) 9.14
Intrinsic tumour suppression. Nature (2004) 8.73
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell (2010) 8.66
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene (2004) 7.92
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev (1999) 7.42
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature (2008) 7.18
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell (2010) 6.94
Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell (2010) 6.88
Telomeres and human disease: ageing, cancer and beyond. Nat Rev Genet (2005) 6.85
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol Cell (2011) 6.83
Cell adhesion and signalling by cadherins and Ig-CAMs in cancer. Nat Rev Cancer (2004) 6.73
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med (1997) 6.55
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol (2011) 6.54
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science (2007) 6.33
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays. Genome Res (2005) 6.08
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res (2011) 6.02
Nucleolar Arf sequesters Mdm2 and activates p53. Nat Cell Biol (1999) 5.78
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nat Genet (2011) 5.62
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
Genes specifically expressed at growth arrest of mammalian cells. Cell (1988) 5.61
EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev (2009) 5.61
Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature (2007) 5.57
Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol (2009) 5.55
The double-edged sword of autophagy modulation in cancer. Clin Cancer Res (2009) 5.46
Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell (2007) 5.40
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature (2001) 5.14
7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature (2001) 5.11
Cysteine cathepsins: multifunctional enzymes in cancer. Nat Rev Cancer (2006) 5.06
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev (2006) 4.94
Necrotic death as a cell fate. Genes Dev (2006) 4.93
AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Res (2010) 4.89
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome. Genome Res (2005) 4.86
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II. Nat Cell Biol (2007) 4.84
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene (2010) 4.81
Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor. Sci Signal (2010) 4.77
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. Gastroenterology (2006) 4.70
CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res (2010) 4.68
A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell (1999) 4.65
3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell (2008) 4.54
Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet (2008) 4.45
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
Conservation of the human telomere sequence (TTAGGG)n among vertebrates. Proc Natl Acad Sci U S A (1989) 4.08
A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene (2006) 3.89
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol (2011) 3.88
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition. Genes Dev (2008) 3.85
Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science (1998) 3.85
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene (2008) 3.79
DD3(PCA3), a very sensitive and specific marker to detect prostate tumors. Cancer Res (2002) 3.78
Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev (2004) 3.74
Differentiating protein-coding and noncoding RNA: challenges and ambiguities. PLoS Comput Biol (2008) 3.66
Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes Dev (1993) 3.63
Epithelial-mesenchymal transition: a cancer researcher's conceptual friend and foe. Am J Pathol (2009) 3.09
Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med (2008) 13.54
Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol (2009) 11.50
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Res (2012) 5.04
MALAT1 -- a paradigm for long noncoding RNA function in cancer. J Mol Med (Berl) (2013) 2.53
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. Hepatology (2014) 2.27
Functionally defective germline variants of sialic acid acetylesterase in autoimmunity. Nature (2010) 2.10
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Mol Cell Biol (2004) 1.96
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol (2012) 1.90
Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells. Cancer Res (2010) 1.82
Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization. RNA Biol (2011) 1.78
Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases. Genome Res (2011) 1.59
The cyclin A1-CDK2 complex regulates DNA double-strand break repair. Mol Cell Biol (2004) 1.43
MicroRNA biogenesis and cancer. Methods Mol Biol (2011) 1.39
Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1). Hepatology (2013) 1.26
miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes. J Invest Dermatol (2012) 1.23
Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer. Cancer Res (2005) 1.22
Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D. Cancer Res (2011) 1.21
Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases. Cancer Sci (2011) 1.18
Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells. Oncogene (2005) 1.04
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma. Hepatology (2014) 1.00
Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis. FASEB J (2012) 0.99
The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis. Genes Dev (2013) 0.98
A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors. Genes Dev (2007) 0.98
Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport. Traffic (2003) 0.97
Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling. J Biol Chem (2011) 0.94
Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells. Endocrinology (2005) 0.91
Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells. Neoplasia (2012) 0.91
DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells. Int J Cancer (2007) 0.90
Cyclin A1 is highly expressed in aggressive testicular germ cell tumors. Cancer Lett (2003) 0.88
A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop. Nucleic Acids Res (2013) 0.87
Loop-miRs: active microRNAs generated from single-stranded loop regions. Nucleic Acids Res (2013) 0.86
Genome-wide screening for prognosis-predicting genes in early-stage non-small-cell lung cancer. Lung Cancer (2004) 0.85
Service oriented data integration for a biomedical research network. Stud Health Technol Inform (2011) 0.84
Cyclin A1 and gametogenesis in fertile and infertile patients: a potential new molecular diagnostic marker. Hum Reprod (2002) 0.83
Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in mice. Cancer Res (2008) 0.83
Analysis of the genetic interactions between Cyclin A1, Atm and p53 during spermatogenesis. Asian J Androl (2007) 0.81
Successive increases in human cyclin A1 promoter activity during spermatogenesis in transgenic mice. Int J Mol Med (2003) 0.78
MicroRNA Northern blotting, precursor cloning, and Ago2-improved RNA interference. Methods Mol Biol (2011) 0.77
A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes. PLoS One (2013) 0.76
RNA meets disease in paradise. RNA Biol (2011) 0.75