Published in J Biol Chem on June 14, 2012
An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η. Biochemistry (2014) 1.23
Translesion DNA synthesis and mutagenesis in eukaryotes. Cold Spring Harb Perspect Biol (2013) 1.09
Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ζ, and Pol κ. J Biol Chem (2012) 1.07
Structural basis of recruitment of DNA polymerase ζ by interaction between REV1 and REV7 proteins. J Biol Chem (2012) 1.02
The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability. Mutat Res (2012) 0.99
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences. PLoS One (2014) 0.84
The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ. FEBS Lett (2012) 0.84
Rev1 promotes replication through UV lesions in conjunction with DNA polymerases η, ι, and κ but not DNA polymerase ζ. Genes Dev (2015) 0.81
Structural insights into the assembly of human translesion polymerase complexes. Protein Cell (2012) 0.80
The Proliferating Cell Nuclear Antigen (PCNA)-interacting Protein (PIP) Motif of DNA Polymerase η Mediates Its Interaction with the C-terminal Domain of Rev1. J Biol Chem (2016) 0.80
Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis. Biochemistry (2016) 0.78
Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1. Nucleic Acids Res (2016) 0.78
The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability. PLoS Genet (2016) 0.78
PCNA tool belts and polymerase bridges form during translesion synthesis. Nucleic Acids Res (2016) 0.77
R.I.P. to the PIP: PCNA-binding motif no longer considered specific: PIP motifs and other related sequences are not distinct entities and can bind multiple proteins involved in genome maintenance. Bioessays (2016) 0.77
The Protein Level of Rev1, a TLS Polymerase in Fission Yeast, Is Strictly Regulated during the Cell Cycle and after DNA Damage. PLoS One (2015) 0.76
RAD18 polymorphisms are associated with platinum-based chemotherapy toxicity in Chinese patients with non-small cell lung cancer. Acta Pharmacol Sin (2016) 0.75
Structure and functional analysis of the BRCT domain of translesion synthesis DNA polymerase Rev1. Biochemistry (2012) 0.75
Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases. Genes (Basel) (2017) 0.75
NMRPipe: a multidimensional spectral processing system based on UNIX pipes. J Biomol NMR (1995) 93.94
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res (2007) 37.31
Protein structure comparison by alignment of distance matrices. J Mol Biol (1993) 34.74
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 24.62
A comprehensive catalogue of somatic mutations from a human cancer genome. Nature (2009) 24.27
A small-cell lung cancer genome with complex signatures of tobacco exposure. Nature (2009) 18.39
TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts. J Biomol NMR (2009) 16.09
Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA. J Mol Biol (2002) 11.20
PCNA, the maestro of the replication fork. Cell (2007) 10.43
The mutation spectrum revealed by paired genome sequences from a lung cancer patient. Nature (2010) 10.04
Mechanisms of cancer drug resistance. Annu Rev Med (2002) 7.91
Deoxycytidyl transferase activity of yeast REV1 protein. Nature (1996) 4.96
Mechanism of replication-coupled DNA interstrand crosslink repair. Cell (2008) 4.53
Mutants of yeast defective in mutation induced by ultraviolet light. Genetics (1971) 3.75
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62
Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol (2012) 3.43
Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis. EMBO J (2003) 2.69
PCNA ubiquitination and REV1 define temporally distinct mechanisms for controlling translesion synthesis in the avian cell line DT40. Mol Cell (2008) 2.29
Evidence for a second function for Saccharomyces cerevisiae Rev1p. Mol Microbiol (2000) 2.29
Repair of endogenous DNA damage. Cold Spring Harb Symp Quant Biol (2000) 2.24
Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7. J Biol Chem (2001) 2.19
Interaction of hREV1 with three human Y-family DNA polymerases. Genes Cells (2004) 2.00
Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein. DNA Repair (Amst) (2004) 2.00
Polkappa protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene. Proc Natl Acad Sci U S A (2002) 1.98
Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy. Proc Natl Acad Sci U S A (2010) 1.95
Error-prone translesion synthesis mediates acquired chemoresistance. Proc Natl Acad Sci U S A (2010) 1.85
REV7, a new gene concerned with UV mutagenesis in yeast. Mol Gen Genet (1985) 1.76
Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol (2012) 1.72
Capping interactions in isolated alpha helices: position-dependent substitution effects and structure of a serine-capped peptide helix. Biochemistry (1993) 1.69
Cellular functions of DNA polymerase zeta and Rev1 protein. Adv Protein Chem (2004) 1.67
Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions. Mol Cell Biol (2006) 1.61
Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1. Nucleic Acids Res (2005) 1.56
Multiple two-polymerase mechanisms in mammalian translesion DNA synthesis. Cell Cycle (2010) 1.51
High resolution 4-D spectroscopy with sparse concentric shell sampling and FFT-CLEAN. J Biomol NMR (2008) 1.49
p53 and p21 regulate error-prone DNA repair to yield a lower mutation load. Mol Cell (2006) 1.44
Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. J Biol Chem (2010) 1.40
Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases. Mol Biol Cell (2008) 1.29
PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. PLoS Genet (2011) 1.27
Analysis of damage tolerance pathways in Saccharomyces cerevisiae: a requirement for Rev3 DNA polymerase in translesion synthesis. Mol Cell Biol (1998) 1.20
DNA mismatch repair and p53 function are major determinants of the rate of development of cisplatin resistance. Mol Cancer Ther (2006) 1.09
Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function. Genes Cells (2009) 1.07
Novel conserved motifs in Rev1 C-terminus are required for mutagenic DNA damage tolerance. DNA Repair (Amst) (2008) 1.03
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells. DNA Repair (Amst) (2009) 1.01
Suppression of hREV1 expression reduces the rate at which human ovarian carcinoma cells acquire resistance to cisplatin. Mol Pharmacol (2005) 0.99
Human REV1 modulates the cytotoxicity and mutagenicity of cisplatin in human ovarian carcinoma cells. Mol Pharmacol (2006) 0.98
Comparative analysis of in vivo interactions between Rev1 protein and other Y-family DNA polymerases in animals and yeasts. DNA Repair (Amst) (2008) 0.98
REV1 is implicated in the development of carcinogen-induced lung cancer. Mol Cancer Res (2009) 0.97
PCNA ubiquitination-independent activation of polymerase η during somatic hypermutation and DNA damage tolerance. DNA Repair (Amst) (2011) 0.91
Translesion synthesis polymerases in the prevention and promotion of carcinogenesis. J Nucleic Acids (2010) 0.89
A hierarchical biology concept framework: a tool for course design. Cell Biol Educ (2004) 8.28
A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance. Nature (2003) 6.06
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest (2004) 4.97
PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nat Med (2004) 4.50
How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model. Nat Rev Microbiol (2007) 3.78
Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance. Microbiol Mol Biol Rev (2009) 3.62
Drosophila PIWI associates with chromatin and interacts directly with HP1a. Genes Dev (2007) 3.46
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation. J Pharmacol Exp Ther (2006) 3.46
Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell (2008) 3.04
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. Mol Cell (2009) 2.74
Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics. Science (2012) 2.72
Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. Cell Stem Cell (2013) 2.71
The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex. J Neurosci (2007) 2.60
A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates. Nature (2006) 2.55
BluB cannibalizes flavin to form the lower ligand of vitamin B12. Nature (2007) 2.53
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest (2011) 2.21
Role of glycogen synthase kinase-3beta in cardioprotection. Circ Res (2009) 2.10
Molecular determinants of a symbiotic chronic infection. Annu Rev Genet (2008) 2.02
A novel class of potent influenza virus inhibitors: polysubstituted acylthiourea and its fused heterocycle derivatives. Bioorg Med Chem Lett (2005) 2.01
Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy. Proc Natl Acad Sci U S A (2010) 1.95
The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase. Proc Natl Acad Sci U S A (2006) 1.92
An experimental study on the noise properties of x-ray CT sinogram data in Radon space. Phys Med Biol (2008) 1.91
Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor. Clin Immunol (2007) 1.91
Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta. EMBO Rep (2007) 1.91
The transcription elongation factor NusA is required for stress-induced mutagenesis in Escherichia coli. Curr Biol (2009) 1.85
Error-prone translesion synthesis mediates acquired chemoresistance. Proc Natl Acad Sci U S A (2010) 1.85
Y-family DNA polymerases in Escherichia coli. Trends Microbiol (2007) 1.78
Beta clamp directs localization of mismatch repair in Bacillus subtilis. Mol Cell (2008) 1.73
Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells. Carcinogenesis (2006) 1.68
Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates. J Biol Chem (2003) 1.67
Regulation and pharmacology of the mitochondrial permeability transition pore. Cardiovasc Res (2009) 1.66
Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis. Curr Pharm Biotechnol (2008) 1.66
Leukotriene A4 hydrolase in rat and human esophageal adenocarcinomas and inhibitory effects of bestatin. J Natl Cancer Inst (2003) 1.63
Chronic intracellular infection of alfalfa nodules by Sinorhizobium meliloti requires correct lipopolysaccharide core. Proc Natl Acad Sci U S A (2002) 1.62
A LuxR homolog controls production of symbiotically active extracellular polysaccharide II by Sinorhizobium meliloti. J Bacteriol (2002) 1.59
Structure of the LpxC deacetylase with a bound substrate-analog inhibitor. Nat Struct Biol (2003) 1.57
Polar Fourier transforms of radially sampled NMR data. J Magn Reson (2006) 1.56
Y-family DNA polymerases respond to DNA damage-independent inhibition of replication fork progression. EMBO J (2006) 1.53
UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB. Mol Cell (2007) 1.51
High resolution 4-D spectroscopy with sparse concentric shell sampling and FFT-CLEAN. J Biomol NMR (2008) 1.49
The reading of components of diabetic retinopathy: an evolutionary approach for filtering normal digital fundus imaging in screening and population based studies. PLoS One (2013) 1.49
Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1. Proc Natl Acad Sci U S A (2005) 1.49
Competencies: a cure for pre-med curriculum. Science (2011) 1.47
cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72. J Biol Chem (2010) 1.47
A coupled level set framework for bladder wall segmentation with application to MR cystography. IEEE Trans Med Imaging (2010) 1.44
Importance of unusually modified lipid A in Sinorhizobium stress resistance and legume symbiosis. Mol Microbiol (2005) 1.43
Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design. Biochemistry (2005) 1.40
Deficiency of a Sinorhizobium meliloti BacA mutant in alfalfa symbiosis correlates with alteration of the cell envelope. J Bacteriol (2002) 1.39
PACES: Protein sequential assignment by computer-assisted exhaustive search. J Biomol NMR (2003) 1.37
p38 Mitogen-activated protein kinase mediates a negative inotropic effect in cardiac myocytes. Circ Res (2002) 1.34
Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12. Proc Natl Acad Sci U S A (2006) 1.33
Similarity to peroxisomal-membrane protein family reveals that Sinorhizobium and Brucella BacA affect lipid-A fatty acids. Proc Natl Acad Sci U S A (2004) 1.31
Effects of plant species coexistence on soil enzyme activities and soil microbial community structure under Cd and Pb combined pollution. J Environ Sci (China) (2010) 1.30
Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proc Natl Acad Sci U S A (2013) 1.30
Anti-transforming growth factor beta receptor II antibody has therapeutic efficacy against primary tumor growth and metastasis through multieffects on cancer, stroma, and immune cells. Clin Cancer Res (2010) 1.28
Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli. Biochemistry (2007) 1.28
Self-maintained escort cells form a germline stem cell differentiation niche. Development (2011) 1.27
Replication is required for the RecA localization response to DNA damage in Bacillus subtilis. Proc Natl Acad Sci U S A (2007) 1.26
Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy. Clin Cancer Res (2006) 1.26
Tumor growth inhibition with cetuximab and chemotherapy in non-small cell lung cancer xenografts expressing wild-type and mutated epidermal growth factor receptor. Clin Cancer Res (2007) 1.25
The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown. Ann N Y Acad Sci (2008) 1.25
DNA polymerase V allows bypass of toxic guanine oxidation products in vivo. J Biol Chem (2007) 1.25
Structure of the endonuclease domain of MutL: unlicensed to cut. Mol Cell (2010) 1.24
Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding. Proc Natl Acad Sci U S A (2007) 1.24
(4,2)D Projection--reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K). J Am Chem Soc (2005) 1.23
The ryanodine receptor modulates the spontaneous beating rate of cardiomyocytes during development. Proc Natl Acad Sci U S A (2002) 1.23
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib. Clin Cancer Res (2005) 1.23
The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events. J Biol Chem (2007) 1.22
Clp and Lon proteases occupy distinct subcellular positions in Bacillus subtilis. J Bacteriol (2008) 1.21
Kinetic analysis of the zinc-dependent deacetylase in the lipid A biosynthetic pathway. Biochemistry (2005) 1.21
The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10. J Biol Chem (2007) 1.21
Radial sampling for fast NMR: Concepts and practices over three decades. Prog Nucl Magn Reson Spectrosc (2010) 1.21
Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing. Mol Microbiol (2010) 1.21
CbrA is a stationary-phase regulator of cell surface physiology and legume symbiosis in Sinorhizobium meliloti. J Bacteriol (2006) 1.20
Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant. Proc Natl Acad Sci U S A (2008) 1.20
Sampling of the NMR time domain along concentric rings. J Magn Reson (2006) 1.20
Positive and negative regulation of APP amyloidogenesis by sumoylation. Proc Natl Acad Sci U S A (2002) 1.20
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli. Proc Natl Acad Sci U S A (2010) 1.18
Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction. J Bacteriol (2008) 1.17
Characterization of hepatic tumors: value of contrast-enhanced coded phase-inversion harmonic angio. AJR Am J Roentgenol (2004) 1.17
Computer-aided detection of colonic polyps with level set-based adaptive convolution in volumetric mucosa to advance CT colonography toward a screening modality. Cancer Manag Res (2009) 1.17
Striking complexity of lipopolysaccharide defects in a collection of Sinorhizobium meliloti mutants. J Bacteriol (2003) 1.17
Unraveling the physiological complexities of antibiotic lethality. Annu Rev Pharmacol Toxicol (2014) 1.16
An EM approach to MAP solution of segmenting tissue mixtures: a numerical analysis. IEEE Trans Med Imaging (2009) 1.16
Groundwater nitrogen pollution and assessment of its health risks: a case study of a typical village in rural-urban continuum, China. PLoS One (2012) 1.15
Functional characterization of bacterial sRNAs using a network biology approach. Proc Natl Acad Sci U S A (2011) 1.14
Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. Chem Biol (2010) 1.14
Filtered backprojection for the reconstruction of a high-resolution (4,2)D CH3-NH NOESY spectrum on a 29 kDa protein. J Am Chem Soc (2005) 1.13
Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. Clin Cancer Res (2004) 1.13
Exo-oligosaccharides of Rhizobium sp. strain NGR234 are required for symbiosis with various legumes. J Bacteriol (2006) 1.12
Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus. Lab Invest (2004) 1.12
Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters by tea and curcumin. Carcinogenesis (2002) 1.11
Rapid protein global fold determination using ultrasparse sampling, high-dynamic range artifact suppression, and time-shared NOESY. J Am Chem Soc (2012) 1.11
Essential role for the BacA protein in the uptake of a truncated eukaryotic peptide in Sinorhizobium meliloti. J Bacteriol (2008) 1.11
High-throughput imaging of bacterial colonies grown on filter plates with application to serum bactericidal assays. J Immunol Methods (2004) 1.11
A comprehensive screening and treatment model for reducing disparities in hepatitis B. Health Aff (Millwood) (2011) 1.10
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. J Clin Invest (2014) 1.10