PubRank

John J Ryan

Author PubWeight™ 72.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dioxins: an overview. Environ Res 2006 2.11
2 Negative regulation of immunoglobulin E-dependent allergic responses by Lyn kinase. J Exp Med 2004 1.91
3 Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res 2012 1.81
4 GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation 2012 1.71
5 Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circ Res 2013 1.67
6 Stat5 expression is critical for mast cell development and survival. Blood 2003 1.48
7 Lung ¹⁸F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension. Am J Respir Crit Care Med 2012 1.42
8 Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J 2013 1.28
9 Cutting edge: genetic variation influences Fc epsilonRI-induced mast cell activation and allergic responses. J Immunol 2007 1.26
10 Impaired FcepsilonRI-dependent gene expression and defective eicosanoid and cytokine production as a consequence of Fyn deficiency in mast cells. J Immunol 2005 1.24
11 Catecholamines in a macrophage cell line. J Neuroimmunol 2003 1.21
12 Kidney transplantation and gender disparity. Am J Nephrol 2005 1.20
13 Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension. Pulm Circ 2013 1.19
14 Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema. J Exp Med 2010 1.19
15 Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation. Immunity 2009 1.17
16 STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease. Blood 2009 1.17
17 A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma. J Allergy Clin Immunol 2012 1.15
18 Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity. J Immunol 2012 1.15
19 IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo. J Immunol 2008 1.11
20 Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes. J Biol Chem 2004 1.11
21 Cutting edge: CD4 T cell-mast cell interactions alter IgE receptor expression and signaling. J Immunol 2008 1.08
22 Synthesis, characterization, and cytotoxicity of a novel highly charged trinuclear platinum compound. Enhancement of cellular uptake with charge. Inorg Chem 2005 1.08
23 Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis. J Immunol 2012 1.03
24 The role of redox signaling in epigenetics and cardiovascular disease. Antioxid Redox Signal 2013 1.03
25 FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. J Mol Med (Berl) 2012 1.03
26 TGF-beta 1 inhibits mast cell Fc epsilon RI expression. J Immunol 2005 1.00
27 Biological consequences of trinuclear platinum complexes: comparison of [[trans-PtCl(NH3)2]2mu-(trans-Pt(NH3)2(H2N(CH2)6-NH2)2)]4+ (BBR 3464) with its noncovalent congeners. Mol Pharmacol 2005 1.00
28 Stat5: an essential regulator of mast cell biology. Mol Immunol 2002 0.99
29 Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension. J Mol Med (Berl) 2013 0.97
30 Polybrominated diphenyl ethers: human tissue levels and toxicology. Rev Environ Contam Toxicol 2004 0.97
31 Stat5 expression is required for IgE-mediated mast cell function. J Immunol 2006 0.96
32 TGF-beta1 attenuates mediator release and de novo Kit expression by human skin mast cells through a Smad-dependent pathway. J Immunol 2008 0.95
33 Macrophage functional polarization (M1/M2) in response to varying fiber and pore dimensions of electrospun scaffolds. Biomaterials 2013 0.95
34 IL-10 inhibits Fc epsilon RI expression in mouse mast cells. J Immunol 2004 0.94
35 IL-3-mediated TNF production is necessary for mast cell development. J Immunol 2006 0.94
36 Heparan sulfate proteoglycan-mediated entry pathway for charged tri-platinum compounds: differential cellular accumulation mechanisms for platinum. Mol Pharm 2012 0.93
37 Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia. Blood 2002 0.93
38 Epigenetic mechanisms of pulmonary hypertension. Pulm Circ 2011 0.93
39 Guidelines for analysis of human milk for environmental chemicals. J Toxicol Environ Health A 2002 0.92
40 Endogenous suppression of mast cell development and survival by IL-4 and IL-10. J Leukoc Biol 2009 0.91
41 IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis. J Immunol 2010 0.90
42 Evolving epidemiology of pulmonary arterial hypertension. Am J Respir Crit Care Med 2012 0.90
43 The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling. Front Immunol 2012 0.90
44 Interleukin-10 induces apoptosis in developing mast cells and macrophages. J Leukoc Biol 2006 0.89
45 IFN-gamma induces apoptosis in developing mast cells. J Immunol 2005 0.89
46 Autocrine actions of macrophage-derived catecholamines on interleukin-1 beta. J Neuroimmunol 2004 0.88
47 cis-Terpenones as an effective chemopreventive agent against aflatoxin B1-induced cytotoxicity and TCDD-induced P450 1A/B activity in HepG2 cells. Chem Res Toxicol 2006 0.87
48 TGFbeta1 induces mast cell apoptosis. Exp Hematol 2006 0.87
49 Interleukin-4 elicits apoptosis of developing mast cells via a Stat6-dependent mitochondrial pathway. Exp Hematol 2004 0.86
50 Myeloid-derived suppressor cells enhance IgE-mediated mast cell responses. J Leukoc Biol 2013 0.86
51 IL-4 selectively enhances FcgammaRIII expression and signaling on mouse mast cells. Cell Immunol 2003 0.83
52 A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding. Chem Commun (Camb) 2014 0.83
53 Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. J Biol Chem 2011 0.83
54 Mast cell-restricted p70 Stat6 isoform is a product of selective proteolysis. Cytokine 2002 0.83
55 Neonatal and childhood teeth in relation to perinatal exposure to polychlorinated biphenyls and dibenzofurans: observations of the Yucheng children in Taiwan. Environ Res 2003 0.83
56 The role of Src family kinases in mast cell effector function. Novartis Found Symp 2005 0.82
57 Costimulation with interleukin-4 and interleukin-10 induces mast cell apoptosis and cell-cycle arrest: the role of p53 and the mitochondrion. Exp Hematol 2004 0.82
58 Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway. J Immunol 2013 0.82
59 A review of the role of electronic health record in genomic research. J Cardiovasc Transl Res 2014 0.82
60 PCB, PCDD and PCDF residues in fin and non-fin fish products from the Canadian retail market 2002. Sci Total Environ 2006 0.80
61 TGF-beta1 inhibits late-stage mast cell maturation. Exp Hematol 2005 0.79
62 Anaplasma phagocytophilum infects mast cells via alpha1,3-fucosylated but not sialylated glycans and inhibits IgE-mediated cytokine production and histamine release. Infect Immun 2011 0.78
63 Fyn kinase is required for optimal humoral responses. PLoS One 2013 0.78
64 Transitioning between endothelin receptor blockers: monitoring to ensure a smooth transition. Can J Cardiol 2012 0.77
65 Promotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes. Biochem Pharmacol 2007 0.77
66 Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. Circ Cardiovasc Genet 2016 0.77
67 Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada. Can J Cardiol 2011 0.77
68 Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth? Circ Res 2011 0.75
69 Platinum anticancer agents and antidepressants: desipramine enhances platinum-based cytotoxicity in human colon cancer cells. J Biol Inorg Chem 2011 0.75
70 Soft-tissue sarcomas: are we making progress? A look at recent publications. Curr Surg 2004 0.75
71 IgE signaling suppresses FcepsilonRIbeta expression. J Leukoc Biol 2009 0.75
72 A KCNE1 missense variant (V47I) causing exercise-induced long QT syndrome (Romano Ward). Int J Cardiol 2011 0.75
73 Blow your own trumpet. S D Med 2007 0.75
74 Screening for colorectal cancer. S D Med 2010 0.75
75 Antidepressants and platinum drugs. Anticancer Res 2014 0.75
76 Roux-en-Y gastric bypass, Nesidioblastosis and diabetes mellitus. S D Med 2006 0.75
77 Bigger may not be better. S D Med 2008 0.75