Published in Oncol Lett on January 24, 2012
Individualized medicine enabled by genomics in Saudi Arabia. BMC Med Genomics (2015) 0.87
RAD51 135G>C and TP53 Arg72Pro polymorphisms and susceptibility to breast cancer in Serbian women. Fam Cancer (2014) 0.81
P53 codon 72 Arg/Pro polymorphism and lung cancer risk in Asians: an updated meta-analysis. Tumour Biol (2013) 0.80
Global cancer statistics. CA Cancer J Clin (2011) 185.92
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res (1994) 11.29
The first 30 years of p53: growing ever more complex. Nat Rev Cancer (2009) 8.00
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat Genet (2003) 6.46
p53 polymorphisms: cancer implications. Nat Rev Cancer (2009) 3.33
No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis of 21 studies involving 24,063 subjects. Breast Cancer Res Treat (2010) 2.12
Polymorphisms in the p53 pathway. Oncogene (2006) 2.06
BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy. Cancer Res (2005) 1.71
P53 codon 72 polymorphism contributes to breast cancer risk: a meta-analysis based on 39 case-control studies. Breast Cancer Res Treat (2009) 1.61
Three common TP53 polymorphisms in susceptibility to breast cancer, evidence from meta-analysis. Breast Cancer Res Treat (2009) 1.56
Breast cancer patients with p53 Pro72 homozygous genotype have a poorer survival. Clin Cancer Res (2005) 1.46
Locally advanced breast cancer in Saudi Arabia: high frequency of stage III in a young population. Med Oncol (1999) 1.33
Phosphatidylinositol 3'-kinase/AKT signaling is activated in medulloblastoma cell proliferation and is associated with reduced expression of PTEN. Clin Cancer Res (2006) 1.31
The codon 47 polymorphism in p53 is functionally significant. J Biol Chem (2005) 1.20
Polymorphic variants in the p53 pathway. Cell Death Differ (2006) 1.20
Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience. BMC Cancer (2007) 1.08
Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients. Breast Cancer Res (2007) 1.08
Polymorphism p53 codon-72 and invasive cervical cancer: a meta-analysis. Int J Gynaecol Obstet (2004) 1.08
p53 codon 72 polymorphism as a risk factor in the development of breast cancer. Mol Cell Biol Res Commun (2000) 1.07
P53 codon 72 polymorphism in breast cancer. Oncol Rep (2003) 1.03
Functional studies of a germ-line polymorphism at codon 47 within the p53 gene. Am J Hum Genet (1993) 1.01
Arg72Pro TP53 polymorphism and cancer susceptibility: a comprehensive meta-analysis of 302 case-control studies. Int J Cancer (2010) 1.00
Polymorphism of TP53 codon 72 showed no association with breast cancer in Iranian women. Cancer Genet Cytogenet (2007) 0.90
P53 gene polymorphisms and breast cancer risk in Arab women. Med Oncol (2010) 0.89
Association between the p53 polymorphisms and breast cancer risk: meta-analysis based on case-control study. Breast Cancer Res Treat (2011) 0.86
Effect of p53 codon 72 genotype on breast cancer survival depends on p53 gene status. Int J Cancer (2008) 0.81
Adjuvant docetaxel for node-positive breast cancer. N Engl J Med (2005) 8.00
The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors. Neoplasia (2006) 3.54
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy. BMC Cancer (2008) 1.63
Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells. Int J Cancer (2007) 1.53
Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes. Cancer Res (2008) 1.45
The p16INK4a tumor suppressor controls p21WAF1 induction in response to ultraviolet light. Nucleic Acids Res (2006) 1.15
Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules. PLoS One (2011) 1.10
Being 40 or younger is an independent risk factor for relapse in operable breast cancer patients: the Saudi Arabia experience. BMC Cancer (2007) 1.08
Age-specific gene expression signatures for breast tumors and cross-species conserved potential cancer progression markers in young women. PLoS One (2013) 1.07
Predictors of sustained virological response to a 48-week course of pegylated interferon alfa-2a and ribavirin in patients infected with hepatitis C virus genotype 4. Ann Saudi Med (2009) 1.06
Causes of uveitis at a referral center in Saudi Arabia. Ocul Immunol Inflamm (2009) 1.04
Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule. Breast Cancer Res (2010) 1.03
p16( INK4a) positively regulates cyclin D1 and E2F1 through negative control of AUF1. PLoS One (2011) 1.02
Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells. Mol Carcinog (2010) 1.01
Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity. PLoS One (2013) 0.97
Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers. BMC Cancer (2013) 0.97
The tumor suppressor p16(INK4a) gene is a regulator of apoptosis induced by ultraviolet light and cisplatin. Oncogene (2004) 0.95
Detection and genotyping of human papilloma virus in cervical cancer specimens from Saudi patients. Int J Gynecol Cancer (2011) 0.95
Proteomics-based signature for human benign prostate hyperplasia and prostate adenocarcinoma. Int J Oncol (2011) 0.94
Prevalence and genotypes' distribution of human papillomavirus in invasive cervical cancer in Saudi Arabia. Gynecol Oncol (2011) 0.94
Deficiency in the repair of UV-induced DNA damage in human skin fibroblasts compromised for the ATM gene. Carcinogenesis (2002) 0.92
Decreased axillary lymph node retrieval in patients after neoadjuvant chemotherapy. Am J Surg (2002) 0.92
Benign tumors from the human nervous system express high levels of survivin and are resistant to spontaneous and radiation-induced apoptosis. J Neurooncol (2005) 0.92
DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise. PLoS One (2013) 0.89
Expression of survivin and p16(INK4a)/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells. Brain Res (2007) 0.88
PAC, a novel curcumin analogue, has anti-breast cancer properties with higher efficiency on ER-negative cells. Breast Cancer Res Treat (2010) 0.88
p16INK4A represses breast stromal fibroblasts migration/invasion and their VEGF-A-dependent promotion of angiogenesis through Akt inhibition. Neoplasia (2012) 0.88
Cytomorphologic differentiation of Hodgkin's lymphoma and Ki-1+ anaplastic large cell lymphoma in fine needle aspirates. Acta Cytol (2003) 0.87
Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer. Breast Cancer Res Treat (2015) 0.87
Curcumin triggers p16-dependent senescence in active breast cancer-associated fibroblasts and suppresses their paracrine procarcinogenic effects. Neoplasia (2013) 0.86
Grading of follicular lymphoma using flow cytometry. Ann Saudi Med (2006) 0.86
Breast stromal fibroblasts from histologically normal surgical margins are pro-carcinogenic. J Pathol (2013) 0.86
Methylation-related mutations in the BRCA1 promoter in peripheral blood cells from cancer-free women. Int J Oncol (2011) 0.85
p16(INK4A) positively regulates p21(WAF1) expression by suppressing AUF1-dependent mRNA decay. PLoS One (2013) 0.84
Prevalence of PIK3CA mutations and the SNP rs17849079 in Arab breast cancer patients. Cancer Biol Ther (2013) 0.83
UV-induced de novo protein synthesis enhances nucleotide excision repair efficiency in a transcription-dependent manner in S. cerevisiae. DNA Repair (Amst) (2003) 0.83
The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females. BMC Cancer (2014) 0.83
Novel FBP1 gene mutations in Arab patients with fructose-1,6-bisphosphatase deficiency. Eur J Pediatr (2009) 0.83
Vincristine and lomustine induce apoptosis and p21(WAF1) up-regulation in medulloblastoma and normal human epithelial and fibroblast cells. J Neurooncol (2007) 0.83
Survivin expression increases during aging and enhances the resistance of aged human fibroblasts to genotoxic stress. Age (Dordr) (2012) 0.83
Camel urine components display anti-cancer properties in vitro. J Ethnopharmacol (2012) 0.82
Outcome of penile cancer in circumcised men. J Urol (2006) 0.82
ATR controls the p21(WAF1/Cip1) protein up-regulation and apoptosis in response to low UV fluences. Mol Carcinog (2011) 0.82
Novel and recurrent mutations in the C1NH gene of Arab patients affected with hereditary angioedema. Int Arch Allergy Immunol (2009) 0.81
Fludarabine-based conditioning chemotherapy for allogeneic hematopoietic stem cell transplantation in acquired severe aplastic anemia. Biol Blood Marrow Transplant (2010) 0.81
18-Fluorodeoxyglucose-positron emission tomography in inflammatory breast cancer. World J Surg (2003) 0.80
The p53/p21 DNA damage-signaling pathway is defective in most meningioma cells. J Neurooncol (2007) 0.80
Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells. Food Chem Toxicol (2012) 0.80
Cellular schwannoma of the paranasal sinuses: initial report of a case. Ear Nose Throat J (2002) 0.80
Ovarian angiosarcoma: a case report and review of the literature. J Med Case Rep (2014) 0.80
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue. Lipids Health Dis (2014) 0.79
Obesity is a significant risk factor for breast cancer in Arab women. BMC Cancer (2014) 0.78
The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA. Mutat Res (2009) 0.78
Clinicopathologic features of hepatic neoplasms in explanted livers: a single institution experience. Ann Saudi Med (2007) 0.78
Response of medulloblastoma cells to vincristine and lomustine: role of TRKC, CTNNB1 and STK15. Anticancer Res (2011) 0.77
Effects of dehydration on corneal tissue absorption of topical azithromycin in rabbits. Curr Eye Res (2005) 0.77
The prevalence, clinical characteristics, and prognosis of diastolic heart failure: a clinical study in elderly Saudi patients with up to 5 years follow-up. Congest Heart Fail (2009) 0.77
The atr protein kinase controls UV-dependent upregulation of p16INK4A through inhibition of Skp2-related polyubiquitination/degradation. Mol Cancer Res (2011) 0.76
TP53 genetic alterations in Arab breast cancer patients: Novel mutations, pattern and distribution. Oncol Lett (2011) 0.76
ATR controls the UV-related upregulation of the CDKN1A mRNA in a Cdk1/HuR-dependent manner. Mol Carcinog (2013) 0.76
Barriers in participant recruitment of diverse ethnicities in the state of Kuwait. Int J Equity Health (2013) 0.75
18-fluorodeoxyglucose positron emission tomography in cystic carcinoma of the breast. Breast J (2002) 0.75
Breast cancer: is there a viral connection? Adv Anat Pathol (2014) 0.75
A comparison of four different methods for outlier detection in bioequivalence studies. J Biopharm Stat (2005) 0.75
Predictors of outcome after radical cystectomy for bladder cancer in saudi patients; single institution experience. J Egypt Natl Canc Inst (2004) 0.75
Aqueous protein level and flare grading. Acta Ophthalmol (2014) 0.75