Interferon regulatory factor-2 is protective against hepatic ischemia-reperfusion injury.

PubWeight™: 0.83‹?›

🔗 View Article (PMC 3468551)

Published in Am J Physiol Gastrointest Liver Physiol on June 28, 2012

Authors

John R Klune1, Rajeev Dhupar, Shoko Kimura, Shinya Ueki, Jon Cardinal, Atsunori Nakao, Gary Nace, John Evankovich, Noriko Murase, Allan Tsung, David A Geller

Author Affiliations

1: Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, Pennsylvania 15213, USA.

Articles cited by this

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-beta gene regulatory elements. Cell (1988) 9.04

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol (2006) 7.98

Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell (1989) 6.11

Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science (1994) 4.50

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development. Cell (1993) 4.46

Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology (1994) 4.32

HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J Exp Med (2007) 3.72

The growing family of interferon regulatory factors. Cytokine Growth Factor Rev (1997) 3.33

Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J Immunol (2004) 3.27

Induction of endogenous IFN-alpha and IFN-beta genes by a regulatory transcription factor, IRF-1. Nature (1989) 3.25

Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes. Proc Natl Acad Sci U S A (1993) 2.46

Role of interferon regulatory factor 1 in induction of nitric oxide synthase. J Exp Med (1994) 2.35

Involvement of the IRF-1 transcription factor in antiviral responses to interferons. Science (1994) 2.28

Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system. Mol Cell Biol (1994) 1.74

Liver ischemia and reperfusion injury: new insights into mechanisms of innate-adaptive immune-mediated tissue inflammation. Am J Transplant (2011) 1.71

Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion. Hepatology (2008) 1.59

Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells. J Exp Med (2000) 1.57

Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2. Nature (1995) 1.54

Interaction of interferon regulatory factor-1 and nuclear factor kappaB during activation of inducible nitric oxide synthase transcription. J Mol Biol (1999) 1.43

IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice. J Immunol (1999) 1.39

The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo. J Exp Med (1996) 1.23

The transcription factor interferon regulatory factor-1 mediates liver damage during ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2006) 1.21

IRF-1 expression induces apoptosis and inhibits tumor growth in mouse mammary cancer cells in vitro and in vivo. Oncogene (2004) 1.19

Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. Mol Cell Biol (2004) 1.15

Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages. Infect Immun (1995) 1.10

Priming of human monocytes for enhanced lipopolysaccharide responses: expression of alpha interferon, interferon regulatory factors, and tumor necrosis factor. Infect Immun (1993) 1.06

Differential dysregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes. J Immunol (1996) 1.03

Binding of the transcription factor interferon regulatory factor-1 to the inducible nitric-oxide synthase promoter. J Biol Chem (1997) 1.02

Critical role of interferon regulatory factor-1 in murine liver transplant ischemia reperfusion injury. Hepatology (2010) 1.01

Heart allograft protection with low-dose carbon monoxide inhalation: effects on inflammatory mediators and alloreactive T-cell responses. Transplantation (2006) 0.99

Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2. J Immunol (2003) 0.98

Cytokine induction of interferon regulatory factor-1 in hepatocytes. Surgery (1993) 0.95

Human adrenomedullin and its binding protein attenuate organ injury and reduce mortality after hepatic ischemia-reperfusion. Ann Surg (2009) 0.89

FK330, a novel inducible nitric oxide synthase inhibitor, prevents ischemia and reperfusion injury in rat liver transplantation. Am J Transplant (2006) 0.86

Differential mechanisms of hepatic vascular dysregulation with mild vs. moderate ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol (2008) 0.85

Bacterial ligand of TLR2 signals Stat activation via induction of IRF1/2 and interferon-alpha production. Cell Signal (2008) 0.85

Donor graft interferon regulatory factor-1 gene transfer worsens liver transplant ischemia/reperfusion injury. Surgery (2009) 0.85

Inhibition of inducible nitric oxide synthase prevents hepatic, but not pulmonary, injury following ischemia-reperfusion of rat liver. Dig Dis Sci (2006) 0.84

Hematopoietic inhibition by interferon-gamma is partially mediated through interferon regulatory factor-1. Blood (1995) 0.82

IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3- and caspase-1-dependent mechanism. J Immunol (2007) 0.80

Effect of activation on neutrophil-induced hepatic microvascular injury in isolated rat liver. Shock (1994) 0.79

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med (2005) 6.86

World review of laparoscopic liver resection-2,804 patients. Ann Surg (2009) 5.96

The international position on laparoscopic liver surgery: The Louisville Statement, 2008. Ann Surg (2009) 5.33

Tolerogenic immunosuppression for organ transplantation. Lancet (2003) 4.09

HMGB1: endogenous danger signaling. Mol Med (2008) 4.02

HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J Exp Med (2007) 3.72

Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J Immunol (2005) 2.78

Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J Exp Med (2006) 2.77

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med (2005) 2.67

Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage. Shock (2006) 2.61

Robotic versus laparoscopic hepatectomy: a matched comparison. Ann Surg (2014) 2.58

Depression, immunity, and survival in patients with hepatobiliary carcinoma. J Clin Oncol (2007) 2.49

Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg (2015) 2.36

Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int (2009) 2.35

Laparoscopic major hepatectomy: an evolution in standard of care. Ann Surg (2009) 2.01

Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology (2011) 1.94

Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. J Am Coll Surg (2005) 1.93

Factors in the pathophysiology of the liver ischemia-reperfusion injury. J Surg Res (2007) 1.89

Thymic carcinoma: a multivariate analysis of factors predictive of survival in 290 patients. Ann Thorac Surg (2012) 1.86

Comparative benefits of laparoscopic vs open hepatic resection: a critical appraisal. Arch Surg (2010) 1.85

Linking oxidative stress to inflammation: Toll-like receptors. Free Radic Biol Med (2010) 1.85

Treatment of hepatic epithelioid hemangioendothelioma: a single-institution experience with 25 cases. Arch Surg (2009) 1.82

Functions of autophagy in normal and diseased liver. Autophagy (2013) 1.81

High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity. J Biol Chem (2010) 1.79

Minimally invasive liver resection for metastatic colorectal cancer: a multi-institutional, international report of safety, feasibility, and early outcomes. Ann Surg (2009) 1.74

Inspection of safety and accuracy of D2 lymph node dissection in laparoscopy-assisted distal gastrectomy. World J Surg (2008) 1.68

Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res (2010) 1.65

Molecular biology of liver ischemia/reperfusion injury: established mechanisms and recent advancements. Surg Clin North Am (2010) 1.65

Immunosuppression for liver transplantation in HCV-infected patients: mechanism-based principles. Liver Transpl (2005) 1.61

Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation. Ann Surg (2012) 1.59

Kidney transplantation under a tolerogenic regimen of recipient pretreatment and low-dose postoperative immunosuppression with subsequent weaning. Ann Surg (2003) 1.52

Biliverdin administration protects against endotoxin-induced acute lung injury in rats. Am J Physiol Lung Cell Mol Physiol (2005) 1.49

A stochastic model for cancer stem cell origin in metastatic colon cancer. Cancer Res (2008) 1.48

The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients. Transplantation (2009) 1.47

Carbon monoxide inhalation protects rat intestinal grafts from ischemia/reperfusion injury. Am J Pathol (2003) 1.47

mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS. Blood (2010) 1.45

Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. Transpl Int (2012) 1.44

Use of alemtuzumab and tacrolimus monotherapy for cadaveric liver transplantation: with particular reference to hepatitis C virus. Transplantation (2004) 1.43

Delayed operating room availability significantly impacts the total hospital costs of an urgent surgical procedure. Surgery (2011) 1.43

Adenosine injection prior to cardioplegia enhances preservation of senescent hearts in rat heterotopic heart transplantation. Eur J Cardiothorac Surg (2012) 1.42

Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement. Biochem Biophys Res Commun (2012) 1.42

High-mobility group box 1 activates caspase-1 and promotes hepatocellular carcinoma invasiveness and metastases. Hepatology (2012) 1.42

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury. J Immunol (2006) 1.42

Comparison of surgical techniques for early-stage thymoma: feasibility of minimally invasive thymectomy and comparison with open resection. J Thorac Cardiovasc Surg (2011) 1.41

Biliverdin protects the functional integrity of a transplanted syngeneic small bowel. Gastroenterology (2004) 1.39

Laparoscopic liver resection. World J Surg (2011) 1.38

Extrahepatic portal vein aneurysm--report of six patients and review of the literature. J Gastrointest Surg (2007) 1.36

Protection against ischemia/reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant (2005) 1.36

miR-375 inhibits autophagy and reduces viability of hepatocellular carcinoma cells under hypoxic conditions. Gastroenterology (2012) 1.36

Benzyl alcohol attenuates acetaminophen-induced acute liver injury in a Toll-like receptor-4-dependent pattern in mice. Hepatology (2014) 1.35

Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide. Am J Physiol Renal Physiol (2004) 1.33

Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling. Cancer Res (2006) 1.33

Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene. Hepatology (2009) 1.31

Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide. Proc Natl Acad Sci U S A (2005) 1.29

Comparing the clinical and economic impact of laparoscopic versus open liver resection. Ann Surg Oncol (2009) 1.29

A mouse model of accelerated liver aging caused by a defect in DNA repair. Hepatology (2012) 1.29

Increasing numbers of hepatic dendritic cells promote HMGB1-mediated ischemia-reperfusion injury. J Leukoc Biol (2006) 1.27

Clinical islet xenotransplantation: how close are we? Diabetes (2012) 1.26

Laparoscopic resection of benign hepatic cysts: a new standard. J Am Coll Surg (2008) 1.26

Identification of a negative response element in the human inducible nitric-oxide synthase (hiNOS) promoter: The role of NF-kappa B-repressing factor (NRF) in basal repression of the hiNOS gene. Proc Natl Acad Sci U S A (2002) 1.25

IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. J Immunol (2008) 1.22

Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges. Ann Surg (2009) 1.21

Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice. Hepatology (2013) 1.21

Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion. Transplantation (2007) 1.21

The transcription factor interferon regulatory factor-1 mediates liver damage during ischemia-reperfusion injury. Am J Physiol Gastrointest Liver Physiol (2006) 1.21

Noninvasive radiofrequency ablation of cancer targeted by gold nanoparticles. Surgery (2008) 1.21

Outcomes of curative treatment for hepatocellular cancer in nonalcoholic steatohepatitis versus hepatitis C and alcoholic liver disease. Hepatology (2012) 1.21

Treatment of unresectable cholangiocarcinoma with gemcitabine-based transcatheter arterial chemoembolization (TACE): a single-institution experience. J Gastrointest Surg (2007) 1.19

Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosis. Transplantation (2005) 1.19