Published in Am J Hum Genet on June 28, 2012
Pitfalls of predicting complex traits from SNPs. Nat Rev Genet (2013) 3.06
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nat Neurosci (2016) 1.78
Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos. Am J Hum Genet (2016) 1.39
POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans. Science (2015) 1.33
Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Am J Hum Genet (2013) 1.27
Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study. Eur J Epidemiol (2015) 1.16
Model-free Estimation of Recent Genetic Relatedness. Am J Hum Genet (2016) 1.15
Genomic ancestry and ethnoracial self-classification based on 5,871 community-dwelling Brazilians (The Epigen Initiative). Sci Rep (2015) 1.05
Estimating and adjusting for ancestry admixture in statistical methods for relatedness inference, heritability estimation, and association testing. BMC Proc (2014) 0.96
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations. Proc Natl Acad Sci U S A (2015) 0.95
PRIMUS: rapid reconstruction of pedigrees from genome-wide estimates of identity by descent. Am J Hum Genet (2014) 0.95
Characterization and correction of error in genome-wide IBD estimation for samples with population structure. Genet Epidemiol (2013) 0.91
Genome-wide patterns of identity-by-descent sharing in the French Canadian founder population. Eur J Hum Genet (2013) 0.90
Robust inference of population structure for ancestry prediction and correction of stratification in the presence of relatedness. Genet Epidemiol (2015) 0.87
Inferring rare disease risk variants based on exact probabilities of sharing by multiple affected relatives. Bioinformatics (2014) 0.86
Construction of relatedness matrices using genotyping-by-sequencing data. BMC Genomics (2015) 0.86
Identity-by-descent graphs offer a flexible framework for imputation and both linkage and association analyses. BMC Proc (2014) 0.84
Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Hum Genet (2013) 0.83
PREST-plus identifies pedigree errors and cryptic relatedness in the GAW18 sample using genome-wide SNP data. BMC Proc (2014) 0.83
Probabilistic models of genetic variation in structured populations applied to global human studies. Bioinformatics (2015) 0.83
Inbreeding among Caribbean Hispanics from the Dominican Republic and its effects on risk of Alzheimer disease. Genet Med (2014) 0.83
The National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pairs genome-wide data. Behav Genet (2014) 0.82
A unified sparse representation for sequence variant identification for complex traits. Genet Epidemiol (2014) 0.81
Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease. PLoS One (2015) 0.81
High level of inbreeding in final phase of 1000 Genomes Project. Sci Rep (2015) 0.80
Prospective association of a genetic risk score and lifestyle intervention with cardiovascular morbidity and mortality among individuals with type 2 diabetes: the Look AHEAD randomised controlled trial. Diabetologia (2015) 0.80
Unique characteristics of the Ainu population in Northern Japan. J Hum Genet (2015) 0.79
A genome-wide association study of asthma symptoms in Latin American children. BMC Genet (2015) 0.78
Genomic Ancestry, Self-Rated Health and Its Association with Mortality in an Admixed Population: 10 Year Follow-Up of the Bambui-Epigen (Brazil) Cohort Study of Ageing. PLoS One (2015) 0.78
Value of Mendelian laws of segregation in families: data quality control, imputation, and beyond. Genet Epidemiol (2014) 0.78
On the Estimation of Heritability with Family-Based and Population-Based Samples. Biomed Res Int (2015) 0.78
A Pipeline for Classifying Relationships Using Dense SNP/SNV Data and Putative Pedigree Information. Genet Epidemiol (2015) 0.77
Global Individual Ancestry Using Principal Components for Family Data. Hum Hered (2015) 0.77
Structured mating: Patterns and implications. PLoS Genet (2017) 0.75
Estimating Telomere Length Heritability in an Unrelated Sample of Adults: Is Heritability of Telomere Length Modified by Life Course Socioeconomic Status? Biodemography Soc Biol (2016) 0.75
Efficient Estimation of Realized Kinship from SNP Genotypes. Genetics (2017) 0.75
Inference of kinship using spatial distributions of SNPs for genome-wide association studies. BMC Genomics (2016) 0.75
Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging. PLoS Negl Trop Dis (2016) 0.75
Detecting Heterogeneity in Population Structure Across the Genome in Admixed Populations. Genetics (2016) 0.75
Polygenic risk scores in familial Alzheimer disease. Neurology (2017) 0.75
Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis. Genet Epidemiol (2016) 0.75
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus. Nat Commun (2017) 0.75
Quickly identifying identical and closely related subjects in large databases using genotype data. PLoS One (2017) 0.75
A Comparative Analysis of Genetic Ancestry and Admixture in the Colombian Populations of Chocó and Medellín. G3 (Bethesda) (2017) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Genomic control for association studies. Biometrics (1999) 64.39
Common SNPs explain a large proportion of the heritability for human height. Nat Genet (2010) 35.02
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
GCTA: a tool for genome-wide complex trait analysis. Am J Hum Genet (2010) 20.73
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity. Genetica (1995) 18.06
Variance component model to account for sample structure in genome-wide association studies. Nat Genet (2010) 15.52
The genetical structure of populations. Ann Eugen (1951) 15.13
Heritability in the genomics era--concepts and misconceptions. Nat Rev Genet (2008) 13.42
Estimation of individual admixture: analytical and study design considerations. Genet Epidemiol (2005) 11.00
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Estimating local ancestry in admixed populations. Am J Hum Genet (2008) 5.90
Robust relationship inference in genome-wide association studies. Bioinformatics (2010) 5.57
Evaluation of candidate genes in case-control studies: a statistical method to account for related subjects. Am J Hum Genet (2001) 4.09
Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet (2007) 3.74
Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet (2003) 3.62
ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. Am J Hum Genet (2010) 2.92
Case-control association testing in the presence of unknown relationships. Genet Epidemiol (2009) 2.63
Inference of locus-specific ancestry in closely related populations. Bioinformatics (2009) 2.54
Inference of unexpected genetic relatedness among individuals in HapMap Phase III. Am J Hum Genet (2010) 2.16
Ancestry-related assortative mating in Latino populations. Genome Biol (2009) 1.79
Population structure can inflate SNP-based heritability estimates. Am J Hum Genet (2011) 1.54
A graphical algorithm for fast computation of identity coefficients and generalized kinship coefficients. Bioinformatics (2009) 1.24
Linkage analysis without defined pedigrees. Genet Epidemiol (2011) 1.20
Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study. Genet Epidemiol (2010) 1.17
Worldwide human relationships inferred from genome-wide patterns of variation. Science (2008) 22.44
Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat Genet (2003) 13.60
Personal omics profiling reveals dynamic molecular and medical phenotypes. Cell (2012) 12.32
The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med (2003) 7.94
Genetic heritability and shared environmental factors among twin pairs with autism. Arch Gen Psychiatry (2011) 6.98
Admixture mapping for hypertension loci with genome-scan markers. Nat Genet (2005) 6.78
Reconstructing genetic ancestry blocks in admixed individuals. Am J Hum Genet (2006) 5.92
Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proc Natl Acad Sci U S A (2003) 5.77
Categorization of humans in biomedical research: genes, race and disease. Genome Biol (2002) 4.84
Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide. Science (2003) 4.48
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med (2006) 3.90
Molecular and evolutionary history of melanism in North American gray wolves. Science (2009) 3.87
A highly significant association between a COMT haplotype and schizophrenia. Am J Hum Genet (2002) 3.52
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health (2005) 3.50
Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet (2004) 3.47
Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat Immunol (2008) 3.43
A randomized trial of the effect of a plant-based dietary pattern on additional breast cancer events and survival: the Women's Healthy Eating and Living (WHEL) Study. Control Clin Trials (2002) 3.41
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat Immunol (2004) 3.25
Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. J Comp Neurol (2004) 3.20
Population stratification confounds genetic association studies among Latinos. Hum Genet (2005) 3.19
Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. J Natl Cancer Inst (2006) 3.08
Homozygosity and linkage disequilibrium. Genetics (2002) 3.04
Genetic admixture and asthma-related phenotypes in Mexican American and Puerto Rican asthmatics. Genet Epidemiol (2005) 3.03
Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. Hum Mol Genet (2008) 2.71
Genomic priorities and public health. Science (2003) 2.69
Comparative and functional genomic analyses of the pathogenicity of phytopathogen Xanthomonas campestris pv. campestris. Genome Res (2005) 2.65
Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors. Breast Cancer Res (2009) 2.59
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology (2012) 2.57
MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett (2008) 2.48
High- and low-fat dairy intake, recurrence, and mortality after breast cancer diagnosis. J Natl Cancer Inst (2013) 2.46
Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet (2011) 2.35
Variation and genetic control of protein abundance in humans. Nature (2013) 2.32
Alcohol consumption and breast cancer recurrence and survival among women with early-stage breast cancer: the life after cancer epidemiology study. J Clin Oncol (2010) 2.31
Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics (2011) 2.31
Sequential phases of cortical specification involve Neurogenin-dependent and -independent pathways. EMBO J (2004) 2.30
Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Immunol (2010) 2.29
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27
Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet (2005) 2.26
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Will the genomics revolution revolutionize psychiatry? Am J Psychiatry (2003) 2.11
It's time for clinicians to reconsider their proscription against the use of soyfoods by breast cancer patients. Oncology (Williston Park) (2013) 2.07
Long-term prognostic role of functional limitations among women with breast cancer. J Natl Cancer Inst (2010) 2.04
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (2006) 2.03
Characterizing the admixed African ancestry of African Americans. Genome Biol (2009) 2.01
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet (2006) 1.98
Physical activity and risk of recurrence and mortality in breast cancer survivors: findings from the LACE study. Cancer Epidemiol Biomarkers Prev (2009) 1.95
Statin use and risk of prostate cancer in the California Men's Health Study cohort. Cancer Epidemiol Biomarkers Prev (2007) 1.94
Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation. Mol Cell Biol (2002) 1.90
Normalization regarding non-random missing values in high-throughput mass spectrometry data. Pac Symp Biocomput (2006) 1.86
A comparison of colon and rectal somatic DNA alterations. Dis Colon Rectum (2009) 1.85
The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication. Trends Genet (2006) 1.84
Increases in plasma carotenoid concentrations in response to a major dietary change in the women's healthy eating and living study. Cancer Epidemiol Biomarkers Prev (2006) 1.78
Admixture mapping and the role of population structure for localizing disease genes. Adv Genet (2008) 1.76
Telephone counseling intervention increases intakes of micronutrient- and phytochemical-rich vegetables, fruit and fiber in breast cancer survivors. J Nutr (2004) 1.75
Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). PLoS Genet (2011) 1.75
MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1. FEBS J (2009) 1.74
Behavioral phenotypic variation in autism multiplex families: evidence for a continuous severity gradient. Am J Med Genet (2002) 1.71
Division of labor, plasticity, and crosstalk between dendritic cell subsets. Curr Opin Immunol (2007) 1.70
The Pathways Study: a prospective study of breast cancer survivorship within Kaiser Permanente Northern California. Cancer Causes Control (2008) 1.70
Ancestral components of admixed genomes in a Mexican cohort. PLoS Genet (2011) 1.67
Efficacy of exercise for menopausal symptoms: a randomized controlled trial. Menopause (2014) 1.67
Geographic distribution of disease mutations in the Ashkenazi Jewish population supports genetic drift over selection. Am J Hum Genet (2003) 1.66
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Dietary pattern influences breast cancer prognosis in women without hot flashes: the women's healthy eating and living trial. J Clin Oncol (2008) 1.64
Assessing genetic contributions to phenotypic differences among 'racial' and 'ethnic' groups. Nat Genet (2004) 1.62
Narrowing the DYT6 dystonia region and evidence for locus heterogeneity in the Amish-Mennonites. Am J Med Genet A (2007) 1.61
Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. Am J Hum Genet (2012) 1.60
Mutation frequencies for glycogen storage disease Ia in the Ashkenazi Jewish population. Am J Med Genet A (2004) 1.59
Characterization of gene-environment interactions for colorectal cancer susceptibility loci. Cancer Res (2012) 1.58
Regulation of the cell cycle gene, BTG2, by miR-21 in human laryngeal carcinoma. Cell Res (2009) 1.58
Partial deficiency of the C-terminal-domain phosphatase of RNA polymerase II is associated with congenital cataracts facial dysmorphism neuropathy syndrome. Nat Genet (2003) 1.57
Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling. J Biol Chem (2008) 1.57
Dietary patterns and breast cancer recurrence and survival among women with early-stage breast cancer. J Clin Oncol (2008) 1.56
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Energy balance and rectal cancer: an evaluation of energy intake, energy expenditure, and body mass index. Nutr Cancer (2003) 1.55
California Men's Health Study (CMHS): a multiethnic cohort in a managed care setting. BMC Public Health (2006) 1.53
Confronting ethnicity-specific disease risk. Nat Genet (2006) 1.52
Body mass index and colon cancer: an evaluation of the modifying effects of estrogen (United States). Cancer Causes Control (2003) 1.52
Suppression of hepatitis B virus replication by microRNA-199a-3p and microRNA-210. Antiviral Res (2010) 1.51
History shaped the geographic distribution of genomic admixture on the island of Puerto Rico. PLoS One (2011) 1.50
Regulation of the transcription factor NF-kappaB1 by microRNA-9 in human gastric adenocarcinoma. Mol Cancer (2010) 1.50
Effects of a dietary intervention and weight change on vasomotor symptoms in the Women's Health Initiative. Menopause (2012) 1.50
Ethnicity and human genetic linkage maps. Am J Hum Genet (2004) 1.50
MicroRNA-214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cells. IUBMB Life (2009) 1.46
A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. Am J Hum Genet (2002) 1.46
A classical likelihood based approach for admixture mapping using EM algorithm. Hum Genet (2006) 1.43
Medical comorbidities predict mortality in women with a history of early stage breast cancer. Breast Cancer Res Treat (2010) 1.42