Charles Kooperberg

Author PubWeight™ 321.70‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA 2002 80.37
2 Outcomes ascertainment and adjudication methods in the Women's Health Initiative. Ann Epidemiol 2003 8.64
3 A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet 2009 8.39
4 The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes Dev 2004 7.57
5 Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the Women's Health Initiative randomized trials. JAMA 2013 7.19
6 Performance of common genetic variants in breast-cancer risk models. N Engl J Med 2010 5.79
7 Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012 5.48
8 Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med 2014 5.47
9 Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial. JAMA 2003 5.26
10 Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 2009 5.14
11 A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet 2010 4.89
12 Recreational physical activity and the risk of breast cancer in postmenopausal women: the Women's Health Initiative Cohort Study. JAMA 2003 4.72
13 Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing. Nat Genet 2002 4.68
14 Regional and cellular gene expression changes in human Huntington's disease brain. Hum Mol Genet 2006 3.91
15 Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med 2016 3.88
16 Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet 2012 3.69
17 Calcium plus vitamin D supplementation and the risk of breast cancer. J Natl Cancer Inst 2008 3.60
18 Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative. Am J Epidemiol 2004 3.53
19 Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trials. Menopause 2004 3.33
20 Conjugated equine estrogens and breast cancer risk in the Women's Health Initiative clinical trial and observational study. Am J Epidemiol 2008 3.05
21 The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study. Am J Epidemiol 2011 2.98
22 Factors associated with 5-year risk of hip fracture in postmenopausal women. JAMA 2007 2.81
23 Estrogen plus progestin therapy and breast cancer in recently postmenopausal women. Am J Epidemiol 2008 2.79
24 Electrocardiographic abnormalities that predict coronary heart disease events and mortality in postmenopausal women: the Women's Health Initiative. Circulation 2006 2.64
25 Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology 2012 2.57
26 Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Hum Mol Genet 2007 2.54
27 Low-fat dietary pattern and change in body-composition traits in the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr 2010 2.43
28 Imputation methods to improve inference in SNP association studies. Genet Epidemiol 2006 2.41
29 Effects of conjugated equine estrogen on stroke in the Women's Health Initiative. Circulation 2006 2.40
30 Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. EMBO J 2006 2.38
31 Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet 2011 2.35
32 Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 2002 2.17
33 Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2010 2.15
34 Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. PLoS Genet 2011 2.13
35 Electrocardiographic predictors of incident congestive heart failure and all-cause mortality in postmenopausal women: the Women's Health Initiative. Circulation 2006 2.13
36 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet 2012 1.96
37 Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Arch Intern Med 2010 1.88
38 Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Am J Epidemiol 2009 1.87
39 Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res 2010 1.82
40 A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet 2013 1.82
41 The emergence of lineage-specific chromosomal topologies from coordinate gene regulation. Proc Natl Acad Sci U S A 2009 1.78
42 Low-fat dietary pattern and lipoprotein risk factors: the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr 2010 1.73
43 Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network. PLoS Genet 2013 1.70
44 Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project. Blood 2013 1.69
45 Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration. J Neurosci 2007 1.66
46 Genome-wide association study of survival in patients with pancreatic adenocarcinoma. Gut 2012 1.66
47 Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study. PLoS One 2012 1.65
48 Characterization of gene-environment interactions for colorectal cancer susceptibility loci. Cancer Res 2012 1.58
49 Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS Genet 2013 1.57
50 Combining biomarkers to detect disease with application to prostate cancer. Biostatistics 2003 1.54
51 Yeast Isw1p forms two separable complexes in vivo. Mol Cell Biol 2003 1.53
52 A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. PLoS Genet 2012 1.53
53 Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum Mol Genet 2005 1.51
54 Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction. Biometrika 2012 1.50
55 Conservation of regional gene expression in mouse and human brain. PLoS Genet 2007 1.47
56 Powerful cocktail methods for detecting genome-wide gene-environment interaction. Genet Epidemiol 2012 1.45
57 Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum Mol Genet 2002 1.45
58 Walking speed and risk of incident ischemic stroke among postmenopausal women. Stroke 2008 1.42
59 Genotype imputation of Metabochip SNPs using a study-specific reference panel of ~4,000 haplotypes in African Americans from the Women's Health Initiative. Genet Epidemiol 2012 1.42
60 Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe Study. Cancer Epidemiol Biomarkers Prev 2011 1.41
61 Genome-wide association study of body height in African Americans: the Women's Health Initiative SNP Health Association Resource (SHARe). Hum Mol Genet 2011 1.37
62 Intrastrand annealing leads to the formation of a large DNA palindrome and determines the boundaries of genomic amplification in human cancer. Mol Cell Biol 2007 1.36
63 A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains. PLoS Genet 2011 1.35
64 Inflammatory, lipid, thrombotic, and genetic markers of coronary heart disease risk in the women's health initiative trials of hormone therapy. Arch Intern Med 2008 1.34
65 Genome-wide association study identifies multiple loci associated with bladder cancer risk. Hum Mol Genet 2013 1.34
66 An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population. PLoS One 2013 1.33
67 Monitoring and reporting of the Women's Health Initiative randomized hormone therapy trials. Clin Trials 2007 1.33
68 Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects. Hum Mol Genet 2002 1.33
69 Simultaneously testing for marginal genetic association and gene-environment interaction. Am J Epidemiol 2012 1.29
70 Fine Mapping and Identification of BMI Loci in African Americans. Am J Hum Genet 2013 1.27
71 Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Am J Hum Genet 2013 1.27
72 Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data. BMC Bioinformatics 2006 1.24
73 Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet 2013 1.24
74 A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. PLoS Genet 2013 1.21
75 Semiparametric estimation exploiting covariate independence in two-phase randomized trials. Biometrics 2008 1.21
76 Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer. Carcinogenesis 2012 1.20
77 Diabetes and risk of pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Cancer Causes Control 2012 1.17
78 Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. Am J Hum Genet 2012 1.16
79 Prior oral contraception and postmenopausal fracture: a Women's Health Initiative observational cohort study. Fertil Steril 2005 1.13
80 Inflammation and hemostasis biomarkers for predicting stroke in postmenopausal women: the Women's Health Initiative Observational Study. J Stroke Cerebrovasc Dis 2008 1.13
81 Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: results from the pancreatic cancer cohort consortium. Cancer Epidemiol Biomarkers Prev 2010 1.11
82 A genome-wide association study of breast cancer in women of African ancestry. Hum Genet 2012 1.11
83 Lipoprotein-associated phospholipase A2, hormone use, and the risk of ischemic stroke in postmenopausal women. Hypertension 2008 1.09
84 Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease. Hum Mol Genet 2002 1.09
85 Associations of serum sex hormone-binding globulin and sex hormone concentrations with hip fracture risk in postmenopausal women. J Clin Endocrinol Metab 2008 1.08
86 Distributions of beta sheets in proteins with application to structure prediction. Proteins 2002 1.08
87 Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study. Hum Mol Genet 2011 1.07
88 Family history of cancer and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Int J Cancer 2010 1.07
89 Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan). Cancer Causes Control 2010 1.07
90 Postmenopausal estrogen and progestin effects on the serum proteome. Genome Med 2009 1.07
91 Imputation of coding variants in African Americans: better performance using data from the exome sequencing project. Bioinformatics 2013 1.05
92 Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study. Circ Cardiovasc Genet 2011 1.05
93 Exome sequencing and directed clinical phenotyping diagnose cholesterol ester storage disease presenting as autosomal recessive hypercholesterolemia. Arterioscler Thromb Vasc Biol 2013 1.03
94 The cross-sectional relationship between body mass index, waist-hip ratio, and cognitive performance in postmenopausal women enrolled in the Women's Health Initiative. J Am Geriatr Soc 2010 1.01
95 Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Exp Gerontol 2009 1.00
96 Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. PLoS One 2012 0.99
97 Homocysteine levels and risk of hip fracture in postmenopausal women. J Clin Endocrinol Metab 2009 0.98
98 Multivariate detection of gene-gene interactions. Genet Epidemiol 2012 0.98
99 HNF1B and endometrial cancer risk: results from the PAGE study. PLoS One 2012 0.97
100 Identifying target populations for screening or not screening using logic regression. Stat Med 2005 0.97
101 Statins, angiotensin-converting enzyme inhibitors, and physical performance in older women. J Am Geriatr Soc 2012 0.97
102 Extreme regression. Biostatistics 2005 0.93
103 Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia. Gut 2013 0.92
104 A variational Bayes discrete mixture test for rare variant association. Genet Epidemiol 2014 0.92
105 A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging. Bioinformatics 2012 0.91
106 Caution in reinterpreting the Women's Health Initiative (WHI) Calcium and Vitamin D Trial breast cancer results. Am J Clin Nutr 2012 0.87
107 Renin-angiotensin system haplotypes and the risk of myocardial infarction and stroke in pharmacologically treated hypertensive patients. Am J Epidemiol 2007 0.86
108 Fine-mapping and initial characterization of QT interval loci in African Americans. PLoS Genet 2012 0.86
109 Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study. BMC Genet 2013 0.86
110 Genome-wide association study of age at menarche in African-American women. Hum Mol Genet 2013 0.85
111 Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia. J Natl Cancer Inst 2014 0.85
112 Estrogen receptor polymorphisms and the vascular effects of hormone therapy. Arterioscler Thromb Vasc Biol 2010 0.85
113 Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study. Circ Cardiovasc Genet 2012 0.84
114 SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association. Biostatistics 2009 0.83
115 Robust estimation for secondary trait association in case-control genetic studies. Am J Epidemiol 2014 0.83
116 Association of DXA-derived bone mineral density and fat mass with African ancestry. J Clin Endocrinol Metab 2013 0.82
117 Validity of Self-Reported Medication Use Compared With Pharmacy Records in a Cohort of Older Women: Findings From the Women's Health Initiative. Am J Epidemiol 2016 0.81
118 Evidence of heterogeneity by race/ethnicity in genetic determinants of QT interval. Epidemiology 2014 0.81
119 African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Am Heart J 2013 0.81
120 Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study. Circ Cardiovasc Genet 2014 0.81
121 Functional redundancy in the nuclear compartmentalization of the late-replicating genome. Nucleus 2014 0.80
122 Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study. Ann Hum Genet 2013 0.80
123 OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study. Bone 2013 0.79
124 Hormone Use, Reproductive History, and Risk of Lung Cancer: The Women's Health Initiative Studies. J Thorac Oncol 2015 0.78
125 Polymorphisms in genes related to one-carbon metabolism are not related to pancreatic cancer in PanScan and PanC4. Cancer Causes Control 2013 0.78
126 No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population. Hum Genet 2013 0.78
127 Adaptively weighted association statistics. Genet Epidemiol 2009 0.77
128 Directed indices for exploring gene expression data. Bioinformatics 2003 0.77
129 Estimating the statistical significance of gene expression changes observed with oligonucleotide arrays. Hum Mol Genet 2002 0.76
130 Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum Mol Genet 2014 0.76
131 Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses. Hum Mol Genet 2015 0.76
132 Corrigendum: Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nat Commun 2015 0.76
133 Long-term oral bisphosphonate use in relation to fracture risk in postmenopausal women with breast cancer: findings from the Women's Health Initiative. Menopause 2016 0.75
134 Fine mapping of 14q24.1 breast cancer susceptibility locus. Hum Genet 2011 0.75
135 Boosting predictions of treatment success. Proc Natl Acad Sci U S A 2010 0.75
136 Associations of Accelerometer-Measured and Self-Reported Sedentary Time With Leukocyte Telomere Length in Older Women. Am J Epidemiol 2017 0.75
137 Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun 2017 0.75
138 New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet 2017 0.75
139 Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet 2017 0.75
140 Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet 2017 0.75