Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery.

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Published in Ther Deliv on April 01, 2011

Authors

Joel C Sunshine1, Corey J Bishop, Jordan J Green

Author Affiliations

1: Johns Hopkins University School of Medicine, Department of Biomedical Engineering, 400 N. Broadway, Smith Building 5017, Baltimore, MD 21231, USA.

Associated clinical trials:

Safety Study of CALAA-01 to Treat Solid Tumor Cancers | NCT00689065

Study of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia Congenita | NCT00716014

Dose Escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous ALN-VSP02 In Patients With Advanced Solid Tumors With Liver Involvement | NCT00882180

Trial to Evaluate Safety and Tolerability of ALN-TTR01 in Transthyretin (TTR) Amyloidosis | NCT01148953

A Study Using Intravitreal Injections of a Small Interfering RNA in Patients With Age-Related Macular Degeneration | NCT00395057

Safety and Efficacy Study of Small Interfering RNA Molecule (Cand5) to Treat Diabetic Macular Edema | NCT00306904

Gene Therapy in Treating Patients With Advanced Head and Neck Cancer | NCT00009841

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia | NCT01064440

Safety and Efficacy of Radiation/Cetuximab Plus EGFR Antisense DNA for Head and Neck Squamous Cell Carcinoma | NCT00903461

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