Published in Blood Cancer J on January 27, 2012
Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia. Blood (2015) 1.26
Genomic characterization of childhood acute lymphoblastic leukemia. Semin Hematol (2013) 1.19
FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors. PLoS One (2013) 1.17
Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199. Cancer Discov (2014) 1.14
Mutational spectrum of adult T-ALL. Oncotarget (2015) 1.09
Early T-cell precursor acute lymphoblastic leukaemia. Curr Opin Hematol (2013) 1.08
Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors. Haematologica (2013) 0.99
The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest. Haematologica (2013) 0.96
Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors. EMBO J (2016) 0.93
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype. Blood (2016) 0.92
DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell (2016) 0.85
Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL. J Hematol Oncol (2016) 0.83
Pathogenesis and prognostication in acute lymphoblastic leukemia. F1000Prime Rep (2014) 0.83
Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients. J Hematol Oncol (2014) 0.82
Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene. PLoS One (2014) 0.81
An early thymic precursor phenotype predicts outcome exclusively in HOXA-overexpressing adult T-cell acute lymphoblastic leukemia: a Group for Research in Adult Acute Lymphoblastic Leukemia study. Haematologica (2016) 0.80
Genomic characterization of pediatric T-cell acute lymphoblastic leukemia reveals novel recurrent driver mutations. Oncotarget (2016) 0.79
The challenge of targeting notch in hematologic malignancies. Front Pediatr (2014) 0.78
Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency. Haematologica (2016) 0.75
Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia. Haematologica (2016) 0.75
The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and Opportunities. Front Pediatr (2016) 0.75
Poor Response to Standard Chemotherapy in Early T-precursor (ETP)-ALL: A Subtype of T-ALL Associated with Unfavourable Outcome: A Brief Report. Indian J Hematol Blood Transfus (2014) 0.75
Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model. Oncotarget (2016) 0.75
High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells. Leuk Res (2015) 0.75
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science (2004) 18.84
The roles of FLT3 in hematopoiesis and leukemia. Blood (2002) 6.14
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol (2009) 4.89
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med (1996) 4.79
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Mol Cell Biol (2003) 4.43
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev Cancer (2006) 3.89
Launching the T-cell-lineage developmental programme. Nat Rev Immunol (2008) 3.86
The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature (2008) 3.48
Activating Notch1 mutations in mouse models of T-ALL. Blood (2005) 3.08
Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B study. J Clin Oncol (2008) 2.98
Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia. Cancer Cell (2011) 2.89
High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood (2006) 2.87
Modern therapy of acute lymphoblastic leukemia. J Clin Oncol (2011) 2.84
Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000. Leukemia (2009) 2.78
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest (2008) 2.73
Activating FLT3 mutations in CD117/KIT(+) T-cell acute lymphoblastic leukemias. Blood (2004) 2.60
Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia. Blood (2005) 2.58
Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia (2009) 2.24
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study. Blood (2003) 2.23
Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia. Blood (2006) 2.10
Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party. J Clin Oncol (2008) 1.99
Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1. Blood (2010) 1.92
Treatment of adult acute lymphoblastic leukemia. Semin Hematol (2009) 1.87
The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling. Cancer Res (2007) 1.85
WT1 mutations in T-ALL. Blood (2009) 1.75
Prethymic phenotype and genotype of pre-T (CD7+/ER-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia. Blood (1989) 1.74
Differential gene expression patterns and interaction networks in BCR-ABL-positive and -negative adult acute lymphoblastic leukemias. J Clin Oncol (2007) 1.64
The role of NOTCH1 signaling in T-ALL. Hematology Am Soc Hematol Educ Program (2009) 1.62
High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia. Blood (2010) 1.60
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood (2010) 1.60
High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults. J Clin Oncol (2006) 1.57
The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function. Leukemia (2010) 1.56
GATA-3 is required for early T lineage progenitor development. J Exp Med (2009) 1.56
Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia. Blood Rev (2010) 1.54
Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia. Haematologica (2009) 1.48
Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia. Clin Cancer Res (2007) 1.44
Presence of Wilms' tumor gene (wt1) transcripts and the WT1 nuclear protein in the majority of human acute leukemias. Leukemia (1995) 1.35
Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome. J Clin Oncol (2007) 1.32
Prognostic implications of Wilms' tumor gene (WT1) expression in patients with de novo acute myeloid leukemia. Haematologica (2004) 1.28
Genetic rearrangements in relation to immunophenotype and outcome in T-cell acute lymphoblastic leukaemia. Best Pract Res Clin Haematol (2010) 1.22
Therapeutic targeting of NOTCH1 signaling in T-cell acute lymphoblastic leukemia. Clin Lymphoma Myeloma (2009) 1.13
FLT3 inhibition as a targeted therapy for acute myeloid leukemia. Curr Opin Oncol (2009) 1.11
T-cell acute lymphoblastic leukemia. Haematologica (2009) 1.04
Gene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223. Haematologica (2010) 1.04
Identification of Flt3⁺CD150⁻ myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential. Blood (2011) 0.96
Mutation analysis of hCDC4 in AML cells identifies a new intronic polymorphism. Int J Med Sci (2006) 0.94
New strategies in acute lymphoblastic leukemia: translating advances in genomics into clinical practice. Clin Cancer Res (2010) 0.93
Expression of the human homologue of rat NG2 in adult acute lymphoblastic leukemia: close association with MLL rearrangement and a CD10(-)/CD24(-)/CD65s(+)/CD15(+) B-cell phenotype. Leukemia (2003) 0.92
Acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program (2002) 0.91
Early T cell differentiation lessons from T-cell acute lymphoblastic leukemia. Prog Mol Biol Transl Sci (2010) 0.89
Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia. Haematologica (2010) 0.89
BAALC-associated gene expression profiles define IGFBP7 as a novel molecular marker in acute leukemia. Leukemia (2010) 0.86
MN1, a novel player in human AML. Blood Cells Mol Dis (2007) 0.85
Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies. Leukemia (2009) 0.85
NOTCH mutations as prognostic markers in T-ALL. Leukemia (2010) 0.83
T-cell lymphoblastic leukemia in early childhood presents NOTCH1 mutations and MLL rearrangements. Leuk Res (2009) 0.79
Detection of FLT3 gene and FLT3/ITD mutation by polymerase chain reaction-single-strand conformation polymorphism in patients with acute lymphoblastic leukemia. Di Yi Jun Yi Da Xue Xue Bao (2005) 0.78
Mutation of FLT3 is not a general phenomenon in CD117-positive T-ALL. Leuk Res (2005) 0.77
A greedy algorithm for aligning DNA sequences. J Comput Biol (2000) 47.89
Comparative analyses of multi-species sequences from targeted genomic regions. Nature (2003) 13.31
arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature (2000) 5.13
Socioeconomic status and psychiatric disorders: the causation-selection issue. Science (1992) 4.95
A new human prostate carcinoma cell line, 22Rv1. In Vitro Cell Dev Biol Anim (1999) 4.93
New insights to the MLL recombinome of acute leukemias. Leukemia (2009) 4.07
Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6. Genome Res (1998) 3.80
Inherited microdeletions in the Angelman and Prader-Willi syndromes define an imprinting centre on human chromosome 15. Nat Genet (1995) 3.79
Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes. Int J Cancer (1988) 3.66
The action of gamma-aminobutyric acid on cortical neurones. Exp Brain Res (1967) 3.45
CD56dimCD16neg cells are responsible for natural cytotoxicity against tumor targets. Leukemia (2005) 3.43
Structure of chromosomal duplicons and their role in mediating human genomic disorders. Genome Res (2000) 3.30
AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J Clin Endocrinol Metab (2003) 3.19
Declining HIV/AIDS mortality in New York City. J Acquir Immune Defic Syndr (1999) 3.01
Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5. Nucleic Acids Res (2001) 2.89
Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia (2012) 2.78
Functional neuroanatomical correlates of hysterical sensorimotor loss. Brain (2001) 2.75
BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing. J Med Genet (2004) 2.75
Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet (1995) 2.73
Chromosome breakage in the Prader-Willi and Angelman syndromes involves recombination between large, transcribed repeats at proximal and distal breakpoints. Am J Hum Genet (1999) 2.71
CACP, encoding a secreted proteoglycan, is mutated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Nat Genet (1999) 2.60
Pain reduction in local anesthetic administration through pH buffering. Ann Emerg Med (1988) 2.59
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J (1997) 2.57
The MLL recombinome of acute leukemias in 2013. Leukemia (2013) 2.55
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain. J Neurosci (2000) 2.49
Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F. Hum Mol Genet (2001) 2.48
The changing purpose of Prader-Willi syndrome clinical diagnostic criteria and proposed revised criteria. Pediatrics (2001) 2.37
Globin gene server: a prototype E-mail database server featuring extensive multiple alignments and data compilation for electronic genetic analysis. Genomics (1994) 2.36
Bilateral human fetal striatal transplantation in Huntington's disease. Neurology (2002) 2.34
Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction. Lancet (1991) 2.33
Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008. Leukemia (2009) 2.30
Emotional facial expressions capture attention. Neurology (2001) 2.25
Improved outcome of zygomycosis in patients with hematological diseases? Leuk Lymphoma (2004) 2.20
Canagliflozin improves glycaemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes Metab (2012) 2.19
Evaluation of mental retardation: recommendations of a Consensus Conference: American College of Medical Genetics. Am J Med Genet (1997) 2.19
CWR22: the first human prostate cancer xenograft with strongly androgen-dependent and relapsed strains both in vivo and in soft agar. Cancer Res (1996) 2.18
Image-guided transorbital roof craniotomy via a suprabrow approach: a surgical series of 72 patients. Neurosurgery (2001) 2.13
The effect of severe caries on the quality of life in young children. Pediatr Dent (1999) 2.10
Cognitive and motor assessment in autopsy-proven corticobasal degeneration. Neurology (2007) 2.09
Cortical inflammation in Alzheimer disease but not dementia with Lewy bodies. Arch Neurol (2000) 2.08
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression. Oncogene (2006) 2.07
Identification of centromeric antigens in dicentric Robertsonian translocations: CENP-C and CENP-E are necessary components of functional centromeres. Hum Mol Genet (1995) 2.04
QALYs for resource allocation: a reply to Burrows and Brown. Aust J Public Health (1993) 1.97
The mosaic structure of human pericentromeric DNA: a strategy for characterizing complex regions of the human genome. Genome Res (2000) 1.97
An analysis of lamellar x-ray diffraction from disordered membrane multilayers with application to data from retinal rod outer segments. Biophys J (1975) 1.97
Macular full-thickness and lamellar holes in association with type 2 idiopathic macular telangiectasia. Eye (Lond) (2008) 1.96
Successful treatment of cerebral aspergillosis with a novel triazole (voriconazole) in a patient with acute leukaemia. Br J Haematol (1997) 1.90
Pervasive occult gastrointestinal bleeding in an Alaska native population with prevalent iron deficiency. Role of Helicobacter pylori gastritis. JAMA (1997) 1.89
Prevalence of antigliadin antibodies in ataxia patients. Neurology (2003) 1.89
Translational inhibition in vitro of human papillomavirus type 16 L2 mRNA mediated through interaction with heterogenous ribonucleoprotein K and poly(rC)-binding proteins 1 and 2. J Biol Chem (1998) 1.88
Difficult extubation due to transfixation of a nasotracheal tube by a Kirschner wire. Anesthesiology (1977) 1.88
A novel human immunodeficiency virus type 1 protein, tev, shares sequences with tat, env, and rev proteins. J Virol (1990) 1.87
BAC microarray analysis of 15q11-q13 rearrangements and the impact of segmental duplications. J Med Genet (2004) 1.87
Transmission of a balanced homologous t(22q;22q) translocation from mother to normal daughter. Clin Genet (1980) 1.84
Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology (2002) 1.84
Acute severe isovolemic anemia impairs cognitive function and memory in humans. Anesthesiology (2000) 1.82
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model. Am J Pathol (2001) 1.81
Relation of serum total cholesterol and high-density lipoprotein cholesterol percentage to the incidence of definite coronary events: twenty-year follow-up of the Donolo-Tel Aviv Prospective Coronary Artery Disease Study. Am J Cardiol (1987) 1.78
Decision aids: are they worth it? A systematic review. J Health Serv Res Policy (2001) 1.78
CWR22: androgen-dependent xenograft model derived from a primary human prostatic carcinoma. Cancer Res (1994) 1.77
Auer rod-like intracytoplasmic inclusions in multiple myeloma. A case report and review of the literature. Int J Lab Hematol (2008) 1.77
A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy. J Clin Invest (1998) 1.77
Prethymic phenotype and genotype of pre-T (CD7+/ER-)-cell leukemia and its clinical significance within adult acute lymphoblastic leukemia. Blood (1989) 1.74
High levels of Wilms' tumor gene (wt1) mRNA in acute myeloid leukemias are associated with a worse long-term outcome. Blood (1997) 1.74
Sequential combination of azacitidine and lenalidomide in del(5q) higher-risk myelodysplastic syndromes or acute myeloid leukemia: a phase I study. Leukemia (2013) 1.71
High-dose chemotherapy with autologous hematopoietic stem-cell support compared with standard-dose chemotherapy in breast cancer patients with 10 or more positive lymph nodes: first results of a randomized trial. J Clin Oncol (2004) 1.70
Treatment of Adult ALL according to protocols of the German Multicenter Study Group for Adult ALL (GMALL). Hematol Oncol Clin North Am (2000) 1.69
Public knowledge, attitudes, and beliefs about homeless people: evidence for compassion fatigue. Am J Community Psychol (1995) 1.69
Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults. Blood (1988) 1.69
CSF evaluation in primary CNS lymphoma patients by PCR of the CDR III IgH genes. Neurology (2002) 1.68
Decentralizing a community mental health center's service delivery system. Hosp Community Psychiatry (1974) 1.68
The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation. Biochim Biophys Acta (1995) 1.67
Validation of a new quality of life questionnaire for benign prostatic hyperplasia. J Clin Epidemiol (1992) 1.65
Relationship of depressive symptoms to hypertension in a household survey in Harlem. Psychosom Med (2001) 1.61
Characterization of neo-centromeres in marker chromosomes lacking detectable alpha-satellite DNA. Hum Mol Genet (1997) 1.60
Neuropsychological function in high-risk breast cancer survivors after stem-cell supported high-dose therapy versus standard-dose chemotherapy: evaluation of long-term treatment effects. Ann Oncol (2005) 1.58
Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo. Dev Biol (1991) 1.56
Reduction of capsular polysaccharide production in Klebsiella pneumoniae by sodium salicylate. Infect Immun (1989) 1.56
A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. N Engl J Med (1990) 1.53
Micro-iontophoretic studies on neurones in the cuneate nucleus. J Physiol (1967) 1.53
Primary central nervous system lymphomas (PCNSL): MRI response criteria revised. Neurology (2005) 1.52
Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. Cancer Res (2000) 1.51
The MLL recombinome of acute leukemias. Leukemia (2006) 1.51
Quantitative Differentiation of Minute Amounts of the Coproporphyrin Isomers (I and III) Based on Fluorescence Behavior. Science (1946) 1.50
SETBP1 mutation analysis in 944 patients with MDS and AML. Leukemia (2013) 1.50
Push-and-pull enteroscopy using the double-balloon technique: method of assessing depth of insertion and training of the enteroscopy technique using the Erlangen Endo-Trainer. Endoscopy (2005) 1.48
Molecular cloning and characterization of 2B7, a rat mRNA which distinguishes smooth muscle cell phenotypes in vitro and is identical to osteopontin (secreted phosphoprotein I, 2aR). Biochem Biophys Res Commun (1991) 1.48
Traffic-related NO2 and the prevalence of asthma and respiratory symptoms in seven year olds. Eur Respir J (1997) 1.48
Mosaic trisomy 22: a case presentation and literature review of trisomy 22 phenotypes. Am J Med Genet (1997) 1.47
Primary intraocular lymphoma: an International Primary Central Nervous System Lymphoma Collaborative Group Report. Ann Oncol (2007) 1.47
THE CONVERSION OF HEMATIN TO BILIRUBIN FOLLOWING INTRAVENOUS ADMINISTRATION IN HUMAN SUBJECTS. J Clin Invest (1945) 1.46
Primary central nervous system (CNS) lymphoma in immunocompetent patients. Ann Hematol (2002) 1.46
Experimental aspects of peripheral vascular occlusion of the intestine. Surg Gynecol Obstet (1965) 1.45
STUDIES OF COPROPORPHYRIN. I. THE PER DIEM EXCRETION AND ISOMER DISTRIBUTION OF COPROPORPHYRIN IN NORMAL HUMAN URINE. J Clin Invest (1949) 1.45
Molecular and cytogenetic analysis of familial Xp deletions. Am J Med Genet (2000) 1.45