Published in Cancer Res on August 03, 2012
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Radiation-induced alterations in mitochondria of the rat heart. Radiat Res (2014) 0.88
Effects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiation. PLoS One (2013) 0.85
A tocotrienol-enriched formulation protects against radiation-induced changes in cardiac mitochondria without modifying late cardiac function or structure. Radiat Res (2015) 0.82
Cardiovascular sequelae of radiation therapy. Clin Res Cardiol (2014) 0.77
Local bone interaction between renin-angiotensin system and kallikrein-kinin system in diabetic rat. Int J Clin Exp Pathol (2015) 0.77
Role of the bradykinin B2 receptor in a rat model of local heart irradiation. Int J Radiat Biol (2015) 0.76
Late Administration of a Palladium Lipoic Acid Complex (POLY-MVA) Modifies Cardiac Mitochondria but Not Functional or Structural Manifestations of Radiation-Induced Heart Disease in a Rat Model. Radiat Res (2017) 0.75
Pathology and biology of radiation-induced cardiac disease. J Radiat Res (2016) 0.75
Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart. Radiother Oncol (2016) 0.75
Advanced Small Animal Conformal Radiation Therapy Device. Technol Cancer Res Treat (2016) 0.75
Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale. Physiol Rev (2010) 2.68
Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapy. J Clin Oncol (2004) 2.68
Precise radiochromic film dosimetry using a flat-bed document scanner. Med Phys (2005) 2.63
Echocardiographic speckle-tracking based strain imaging for rapid cardiovascular phenotyping in mice. Circ Res (2011) 2.06
Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radic Biol Med (2009) 2.04
Cardioprotective effects of a selective B(2) receptor agonist of bradykinin post-acute myocardial infarct. Am J Hypertens (2010) 1.70
NADPH oxidase 4 promotes endothelial angiogenesis through endothelial nitric oxide synthase activation. Circulation (2011) 1.68
Bradykinin prevents reperfusion injury by targeting mitochondrial permeability transition pore through glycogen synthase kinase 3beta. J Mol Cell Cardiol (2006) 1.42
Nox2 NADPH oxidase promotes pathologic cardiac remodeling associated with Doxorubicin chemotherapy. Cancer Res (2010) 1.35
Mast cell chymase limits the cardiac efficacy of Ang I-converting enzyme inhibitor therapy in rodents. J Clin Invest (2010) 1.26
Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation. Circ Res (2004) 1.26
Heart irradiation as a risk factor for radiation pneumonitis. Acta Oncol (2010) 1.20
Comparison of heart and coronary artery doses associated with intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for distal esophageal cancer. Int J Radiat Oncol Biol Phys (2012) 1.17
Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays. PLoS One (2011) 1.15
NADPH oxidases and cardiac remodelling. Heart Fail Rev (2011) 1.14
Cardioprotective effects of tanshinone IIA pretreatment via kinin B2 receptor-Akt-GSK-3β dependent pathway in experimental diabetic cardiomyopathy. Cardiovasc Diabetol (2011) 1.11
The impact of heart irradiation on dose-volume effects in the rat lung. Int J Radiat Oncol Biol Phys (2007) 1.09
Signaling by the angiotensin-converting enzyme. Circ Res (2006) 1.08
Kinins and kinin receptors: importance for the activation of leukocytes. J Leukoc Biol (2000) 1.08
The mitochondrial permeability transition pore and cyclophilin D in cardioprotection. Biochim Biophys Acta (2011) 1.07
Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res (2005) 1.06
Dosimetric comparison of three different involved nodal irradiation techniques for stage II Hodgkin's lymphoma patients: conventional radiotherapy, intensity-modulated radiotherapy, and three-dimensional proton radiotherapy. Int J Radiat Oncol Biol Phys (2009) 1.05
Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide. J Mol Cell Cardiol (1999) 1.04
Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. Physiol Genomics (2004) 1.02
Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myocardial infarction. Hypertension (2002) 1.01
Cleavage of high-molecular-weight kininogen by elastase and tryptase is inhibited by ferritin. Am J Physiol Lung Cell Mol Physiol (2008) 1.01
Radiation induced heart disease: systemic disorders in heart disease. Heart (2009) 0.99
The paradoxical role of inflammation in cardiac repair and regeneration. J Cardiovasc Transl Res (2010) 0.97
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Role of kinins in chronic heart failure and in the therapeutic effect of ACE inhibitors in kininogen-deficient rats. Am J Physiol Heart Circ Physiol (2000) 0.96
Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications. PLoS One (2010) 0.96
Acute radiation effects on cardiac function detected by strain rate imaging in breast cancer patients. Int J Radiat Oncol Biol Phys (2010) 0.96
A study on the influence of breathing phases in intensity-modulated radiotherapy of lung tumours using four-dimensional CT. Br J Radiol (2009) 0.95
Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat. Experientia (1980) 0.94
Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. Life Sci (2007) 0.93
Regulation of cardiac bradykinin B1- and B2-receptor mRNA in experimental ischemic, diabetic, and pressure-overload-induced cardiomyopathy. Int Immunopharmacol (2002) 0.89
Bradykinin B2 receptor antagonism attenuates inflammation, mast cell infiltration and fibrosis in remote myocardium after infarction in rats. Clin Exp Pharmacol Physiol (2005) 0.87
NADPH oxidase contributes to coronary endothelial dysfunction in the failing heart. Am J Physiol Heart Circ Physiol (2009) 0.86
The brown Norway rats and the kinin system. Peptides (1996) 0.86
Bradykinin inhibits development of myocardial infarction through B2 receptor signalling by increment of regional blood flow around the ischaemic lesions in rats. Br J Pharmacol (2003) 0.83
Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion. Free Radic Biol Med (2010) 0.81
Cardioprotective properties of bradykinin: role of the B(2) receptor. Hypertens Res (2010) 0.81
Attenuation of left ventricular dysfunction by an ACE inhibitor after myocardial infarction in a kininogen-deficient rat model. Biol Chem (2008) 0.79
Plasma kininogen deficiency: associated defective secretion of kininogens by primary cultures of hepatocytes from brown Norway Katholiek rats. J Biochem (1993) 0.78
L-arginine mitigates radiation-induced early changes in cardiac dysfunction: the role of inflammatory pathways. Radiat Res (2011) 0.78
The role of a membrane-bound glutathione transferase in the peroxynitrite-induced mitochondrial permeability transition pore: formation of a disulfide-linked protein complex. Arch Biochem Biophys (2011) 0.77
Effects of radiation therapy on vascular responsiveness. J Cardiovasc Pharmacol (2001) 0.76
Recombinant adeno-associated virus-mediated human kallikrein gene therapy protects against hypertensive target organ injuries through inhibiting cell apoptosis. Acta Pharmacol Sin (2009) 0.76
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler Thromb Vasc Biol (2008) 5.44
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med (2005) 4.84
Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula. J Mol Med (Berl) (2006) 4.00
Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer (2004) 3.83
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest (2003) 3.62
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study. Circulation (2007) 3.59
Animal models for medical countermeasures to radiation exposure. Radiat Res (2010) 2.83
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation (2004) 2.64
A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circ Res (2006) 2.50
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Assessment of diffuse myocardial fibrosis in rats using small-animal Look-Locker inversion recovery T1 mapping. Circ Cardiovasc Imaging (2011) 2.21
Comparison of mortality rates in statin users versus nonstatin users in a United States veteran population. Am J Cardiol (2006) 2.19
Protective arms of the renin-angiotensin-system in neurological disease. Clin Exp Pharmacol Physiol (2013) 2.18
The endothelium and vascular inflammation in diabetes. Diab Vasc Dis Res (2007) 2.00
Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems. Disaster Med Public Health Prep (2011) 1.93
The beta-lactam antibiotic, ceftriaxone, dramatically improves survival, increases glutamate uptake and induces neurotrophins in stroke. J Hypertens (2008) 1.91
The radiotherapeutic injury--a complex 'wound'. Radiother Oncol (2002) 1.82
Candesartan but not ramipril pretreatment improves outcome after stroke and stimulates neurotrophin BNDF/TrkB system in rats. J Hypertens (2008) 1.81
Angiotensin AT1/AT2 receptors: regulation, signalling and function. Blood Press (2003) 1.79
Regulation of transport of the angiotensin AT2 receptor by a novel membrane-associated Golgi protein. Arterioscler Thromb Vasc Biol (2004) 1.75
Expression of the proto-oncogene Fos after exposure to radiofrequency radiation relevant to wireless communications. Radiat Res (2005) 1.73
Radiation-related heart disease: current knowledge and future prospects. Int J Radiat Oncol Biol Phys (2010) 1.72
Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction? Circulation (2008) 1.72
Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin. Circ Res (2008) 1.64
PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin. Hypertension (2005) 1.60
Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity. Diabetes (2005) 1.58
Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat Med (2012) 1.58
Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation. Hypertension (2009) 1.54
Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury. FASEB J (2005) 1.54
Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension (2010) 1.50
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Angiotensin receptor blockers: therapeutic targets and cardiovascular protection. Blood Press (2005) 1.49
Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled. Am J Hypertens (2004) 1.48
Angiotensin II and the fibroproliferative response to acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 1.46
Normal tissue effects: reporting and analysis. Semin Radiat Oncol (2003) 1.44
High prevalence and poor control of hypertension in primary care: cross-sectional study. J Hypertens (2004) 1.43
Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol (2007) 1.42
Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis. J Hypertens (2014) 1.40
Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Am J Pathol (2002) 1.39
Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism. Diabetes (2007) 1.39
Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma. PLoS Genet (2008) 1.35
RAS blockade with ARB and ACE inhibitors: current perspective on rationale and patient selection. Clin Res Cardiol (2008) 1.34
Adiponectin translation is increased by the PPARgamma agonists pioglitazone and omega-3 fatty acids. Am J Physiol Endocrinol Metab (2008) 1.33
gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. Radiat Res (2009) 1.32
Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo. J Appl Physiol (1985) (2008) 1.30
Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. Int J Radiat Biol (2009) 1.29
Acidic pH and capsaicin activate mechanosensitive group IV muscle receptors in the rat. Pain (2004) 1.27
Protection from adverse myocardial remodeling secondary to chronic volume overload in mast cell deficient rats. J Mol Cell Cardiol (2008) 1.27
Decreasing the adverse effects of cancer therapy: National Cancer Institute guidance for the clinical development of radiation injury mitigators. Clin Cancer Res (2010) 1.22
Excitatory and modulatory effects of inflammatory cytokines and neurotrophins on mechanosensitive group IV muscle afferents in the rat. Pain (2005) 1.19
Non-peptide AT2-receptor agonists. Curr Opin Pharmacol (2010) 1.15
Cardiac c-kit+AT2+ cell population is increased in response to ischemic injury and supports cardiomyocyte performance. Stem Cells (2009) 1.15
Novel therapeutic targets for hypertension. Nat Rev Cardiol (2010) 1.13
Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension. Hypertension (2011) 1.12
Chronic pretreatment with candesartan improves recovery from focal cerebral ischaemia in rats. J Hypertens (2003) 1.11
Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition. Blood Coagul Fibrinolysis (2006) 1.11
Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis (2008) 1.11
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol. Int J Radiat Oncol Biol Phys (2008) 1.10
Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: a sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients. Cardiovasc Diabetol (2007) 1.10
Renin-angiotensin system blockade and cognitive function in patients at high risk of cardiovascular disease: analysis of data from the ONTARGET and TRANSCEND studies. Lancet Neurol (2010) 1.10
Angiotensin II accelerates functional recovery in the rat sciatic nerve in vivo: role of the AT2 receptor and the transcription factor NF-kappaB. FASEB J (2003) 1.10
First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation. Disaster Med Public Health Prep (2011) 1.10
Defining pelvic-radiation disease for the survivorship era. Lancet Oncol (2010) 1.09
AT2 receptor agonists: hypertension and beyond. Curr Opin Nephrol Hypertens (2012) 1.09
Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats. Am J Physiol Heart Circ Physiol (2003) 1.09
Identification of noncytotoxic and IL-10-producing CD8+AT2R+ T cell population in response to ischemic heart injury. J Immunol (2010) 1.08
Direct angiotensin II type 2 receptor stimulation in Nω-nitro-L-arginine-methyl ester-induced hypertension: the effect on pulse wave velocity and aortic remodeling. Hypertension (2012) 1.07
Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. Blood Coagul Fibrinolysis (2003) 1.07
Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation. Radiat Res (2010) 1.07
Development of a combined radiation and burn injury model. J Burn Care Res (2011) 1.07
Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res (2005) 1.06
Prevention of liver cancer cachexia-induced cardiac wasting and heart failure. Eur Heart J (2013) 1.06
Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome. Hernia (2006) 1.05
Adenosine triphosphate as a stimulant for nociceptive and non-nociceptive muscle group IV receptors in the rat. Neurosci Lett (2003) 1.05
Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability. Am J Physiol Heart Circ Physiol (2011) 1.04
Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol (2009) 1.04
Radiation damage to the gastrointestinal tract: mechanisms, diagnosis, and management. Curr Opin Support Palliat Care (2007) 1.03
Dead or alive? Autofluorescence distinguishes heat-fixed from viable cells. Int J Hyperthermia (2009) 1.03
The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion. Radiat Res (2009) 1.02
Genetic kininogen deficiency contributes to aortic aneurysm formation but not to atherosclerosis. Physiol Genomics (2004) 1.02
PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice. Cardiovasc Diabetol (2010) 1.02