Published in Cell Rep on August 02, 2012
A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians. Dev Cell (2015) 1.54
JNK controls the onset of mitosis in planarian stem cells and triggers apoptotic cell death required for regeneration and remodeling. PLoS Genet (2014) 1.51
Rethinking differentiation: stem cells, regeneration, and plasticity. Cell (2014) 1.41
Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria. Elife (2014) 1.13
Muscle cells provide instructions for planarian regeneration. Cell Rep (2013) 1.13
An RNAi screen reveals intestinal regulators of branching morphogenesis, differentiation, and stem cell proliferation in planarians. Dev Cell (2012) 1.12
SmedGD 2.0: The Schmidtea mediterranea genome database. Genesis (2015) 1.12
Neoblast specialization in regeneration of the planarian Schmidtea mediterranea. Stem Cell Reports (2014) 1.11
Specialized progenitors and regeneration. Development (2013) 1.10
RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: methodology and dynamics. Dev Dyn (2013) 1.07
Tissue absence initiates regeneration through follistatin-mediated inhibition of activin signaling. Elife (2013) 0.98
Follistatin antagonizes activin signaling and acts with notum to direct planarian head regeneration. Proc Natl Acad Sci U S A (2013) 0.97
A mex3 homolog is required for differentiation during planarian stem cell lineage development. Elife (2015) 0.95
Using phylogenetically-informed annotation (PIA) to search for light-interacting genes in transcriptomes from non-model organisms. BMC Bioinformatics (2014) 0.90
The planarian regeneration transcriptome reveals a shared but temporally shifted regulatory program between opposing head and tail scenarios. BMC Genomics (2013) 0.89
Egr-5 is a post-mitotic regulator of planarian epidermal differentiation. Elife (2015) 0.87
Wnt/Notum spatial feedback inhibition controls neoblast differentiation to regulate reversible growth of the planarian brain. Development (2015) 0.84
Novel monoclonal antibodies to study tissue regeneration in planarians. BMC Dev Biol (2015) 0.84
zic-1 Expression in Planarian neoblasts after injury controls anterior pole regeneration. PLoS Genet (2014) 0.84
Unusually Large Number of Mutations in Asexually Reproducing Clonal Planarian Dugesia japonica. PLoS One (2015) 0.83
Types or States? Cellular Dynamics and Regenerative Potential. Trends Cell Biol (2015) 0.82
COE loss-of-function analysis reveals a genetic program underlying maintenance and regeneration of the nervous system in planarians. PLoS Genet (2014) 0.82
Posterior eyespots in larval chitons have a molecular identity similar to anterior cerebral eyes in other bilaterians. Evodevo (2015) 0.80
Set1 and MLL1/2 Target Distinct Sets of Functionally Different Genomic Loci In Vivo. Cell Rep (2015) 0.79
Planarian Phototactic Assay Reveals Differential Behavioral Responses Based on Wavelength. PLoS One (2014) 0.79
Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain. Elife (2016) 0.79
Planarians as a model to assess in vivo the role of matrix metalloproteinase genes during homeostasis and regeneration. PLoS One (2013) 0.78
GPCRs Direct Germline Development and Somatic Gonad Function in Planarians. PLoS Biol (2016) 0.78
Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration. Dev Cell (2017) 0.77
Planarian Body-Wall Muscle: Regeneration and Function beyond a Simple Skeletal Support. Front Cell Dev Biol (2016) 0.77
A functional genomics screen identifies an Importin-α homolog as a regulator of stem cell function and tissue patterning during planarian regeneration. BMC Genomics (2015) 0.77
Hedgehog signaling regulates gene expression in planarian glia. Elife (2016) 0.76
On-chip immobilization of planarians for in vivo imaging. Sci Rep (2014) 0.76
Go ahead, grow a head! A planarian's guide to anterior regeneration. Regeneration (Oxf) (2016) 0.76
A functional genomics screen in planarians reveals regulators of whole-brain regeneration. Elife (2016) 0.76
Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias. Elife (2016) 0.76
Adhesive organ regeneration in Macrostomum lignano. BMC Dev Biol (2016) 0.76
Characterization of a flatworm inositol (1,4,5) trisphosphate receptor (IP₃R) reveals a role in reproductive physiology. Cell Calcium (2013) 0.75
Temporal regulation of planarian eye regeneration. Regeneration (Oxf) (2016) 0.75
Forkhead containing transcription factor Albino controls tetrapyrrole-based body pigmentation in planarian. Cell Discov (2016) 0.75
Embryonic origin of adult stem cells required for tissue homeostasis and regeneration. Elife (2017) 0.75
The NuRD complex component p66 suppresses photoreceptor neuron regeneration in planarians. Regeneration (Oxf) (2016) 0.75
Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration. Development (2017) 0.75
Digital gene expression approach over multiple RNA-Seq data sets to detect neoblast transcriptional changes in Schmidtea mediterranea. BMC Genomics (2015) 0.75
The Akt signaling pathway is required for tissue maintenance and regeneration in planarians. BMC Dev Biol (2016) 0.75
Generation of cell type-specific monoclonal antibodies for the planarian and optimization of sample processing for immunolabeling. BMC Dev Biol (2014) 0.75
Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea. J Biol Chem (2016) 0.75
Hierarchies in light sensing and dynamic interactions between ocular and extraocular sensory networks in a flatworm. Sci Adv (2017) 0.75
The miR-124 family of microRNAs is critical for regeneration of the brain and visual system in the planarian Schmidtea mediterranea. Development (2017) 0.75
The retinal pigment epithelium in visual function. Physiol Rev (2005) 8.59
Fundamentals of planarian regeneration. Annu Rev Cell Dev Biol (2004) 4.60
SMEDWI-2 is a PIWI-like protein that regulates planarian stem cells. Science (2005) 3.83
Ciliary photoreceptors with a vertebrate-type opsin in an invertebrate brain. Science (2004) 3.81
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration. Science (2011) 3.72
Double-stranded RNA specifically disrupts gene expression during planarian regeneration. Proc Natl Acad Sci U S A (1999) 3.61
Bromodeoxyuridine specifically labels the regenerative stem cells of planarians. Dev Biol (2000) 2.94
Specification of the vertebrate eye by a network of eye field transcription factors. Development (2003) 2.86
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J (2004) 2.55
Genome-wide analyses reveal a role for peptide hormones in planarian germline development. PLoS Biol (2010) 2.47
Formaldehyde-based whole-mount in situ hybridization method for planarians. Dev Dyn (2009) 2.42
Role of myosin VI in the differentiation of cochlear hair cells. Dev Biol (1999) 2.26
Phototransduction and retinal degeneration in Drosophila. Pflugers Arch (2007) 2.15
Genetic insights into the morphogenesis of inner ear hair cells. Nat Rev Genet (2004) 2.11
Regulation of melanogenesis--controversies and new concepts. Exp Dermatol (2007) 2.00
Evolution of eyes and photoreceptor cell types. Int J Dev Biol (2003) 1.99
Signaling circuitries in development: insights from the retinal determination gene network. Development (2005) 1.94
Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther (2000) 1.78
Usher syndrome: animal models, retinal function of Usher proteins, and prospects for gene therapy. Vision Res (2007) 1.72
Activation and regulation of store-operated calcium entry. J Cell Mol Med (2010) 1.70
Structure of the planarian central nervous system (CNS) revealed by neuronal cell markers. Zoolog Sci (1998) 1.68
Phototransduction and the evolution of photoreceptors. Curr Biol (2010) 1.67
Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt. Genes Dev (2002) 1.58
Functional roles of bestrophins in ocular epithelia. Prog Retin Eye Res (2009) 1.52
Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. J Cell Biol (2004) 1.47
Bestrophins and retinopathies. Pflugers Arch (2010) 1.41
The evolution of eyes and visually guided behaviour. Philos Trans R Soc Lond B Biol Sci (2009) 1.35
dlx and sp6-9 Control optic cup regeneration in a prototypic eye. PLoS Genet (2011) 1.29
Whirlin complexes with p55 at the stereocilia tip during hair cell development. Proc Natl Acad Sci U S A (2006) 1.26
Senile hair graying: H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair. FASEB J (2009) 1.25
Distinct structural domains in the planarian brain defined by the expression of evolutionarily conserved homeobox genes. Dev Genes Evol (1999) 1.25
The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. J Neurosci (2006) 1.24
Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development. Development (2008) 1.23
Drosophila photoreceptors and signaling mechanisms. Front Cell Neurosci (2009) 1.23
Eye evolution: common use and independent recruitment of genetic components. Philos Trans R Soc Lond B Biol Sci (2009) 1.20
Searching for the prototypic eye genetic network: Sine oculis is essential for eye regeneration in planarians. Proc Natl Acad Sci U S A (2000) 1.19
Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development (2011) 1.15
Melanopsin and mechanisms of non-visual ocular photoreception. J Biol Chem (2011) 1.12
The mouse Ovol2 gene is required for cranial neural tube development. Dev Biol (2006) 1.11
Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat. Neuroscience (1999) 1.11
Emerging systems: between vertebrates and arthropods, the Lophotrochozoa. Curr Opin Genet Dev (2003) 1.04
Djeyes absent (Djeya) controls prototypic planarian eye regeneration by cooperating with the transcription factor Djsix-1. Dev Biol (2004) 1.03
The genetic network of prototypic planarian eye regeneration is Pax6 independent. Development (2002) 1.03
Abnormal sperm and photoreceptor axonemes in Usher's syndrome. Arch Ophthalmol (1986) 1.03
Production and utilization of hydrogen peroxide associated with melanogenesis and tyrosinase-mediated oxidations of DOPA and dopamine. FEBS J (2005) 1.00
Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. Genes Cells (2007) 0.99
Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice. Genomics (2002) 0.98
Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia. PLoS One (2010) 0.94
Identification and distribution of tryptophan hydroxylase (TPH)-positive neurons in the planarian Dugesia japonica. Neurosci Res (2007) 0.93
Characterization of the pigment produced by the planarian, Dugesia ryukyuensis. Pigment Cell Res (2006) 0.92
Mouse Dach1 and Dach2 are redundantly required for Müllerian duct development. Genesis (2008) 0.92
pHi regulation in frog retinal pigment epithelium: two apical membrane mechanisms. Am J Physiol (1991) 0.92
Induction of glutathione S-transferase hGST 5.8 is an early response to oxidative stress in RPE cells. Invest Ophthalmol Vis Sci (1999) 0.87
Building a fly eye: terminal differentiation events of the retina, corneal lens, and pigmented epithelia. Curr Top Dev Biol (2010) 0.87
Morphological and molecular development of the eyes during embryogenesis of the freshwater planarian Schmidtea polychroa. Dev Genes Evol (2012) 0.87
Cysteine deprivation promotes eumelanogenesis in human melanoma cells. J Invest Dermatol (1996) 0.86
Regulation of glucose transporters during development of the retinal pigment epithelium. Brain Res Dev Brain Res (2000) 0.86
Proton-lactate cotransport in the apical membrane of frog retinal pigment epithelium. Exp Eye Res (1994) 0.86
Association between oxidative stress and macromolecular damage in elderly patients with age-related macular degeneration. Aging Clin Exp Res (2011) 0.85
Inhibitory Smads and bone morphogenetic protein (BMP) modulate anterior photoreceptor cell number during planarian eye regeneration. Int J Dev Biol (2012) 0.84
Planarian Gtsix3, a member of the Six/so gene family, is expressed in brain branches but not in eye cells. Mech Dev (2002) 0.84
The excitation cascade of Limulus ventral photoreceptors: guanylate cyclase as the link between InsP3-mediated Ca2+ release and the opening of cGMP-gated channels. BMC Neurosci (2004) 0.83
The Drosophila sox gene, fish-hook, is required for postembryonic development. Dev Biol (2000) 0.78
Expression of a retinal homeobox (Rx) gene during planarian regeneration. Int J Dev Biol (2008) 0.78
Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration. Science (2011) 3.72
Smed-betacatenin-1 is required for anteroposterior blastema polarity in planarian regeneration. Science (2007) 2.77
Wnt signaling and the polarity of the primary body axis. Cell (2009) 2.46
Ingestion of bacterially expressed double-stranded RNA inhibits gene expression in planarians. Proc Natl Acad Sci U S A (2003) 2.44
The cellular basis for animal regeneration. Dev Cell (2011) 2.14
Genetic regulators of a pluripotent adult stem cell system in planarians identified by RNAi and clonal analysis. Cell Stem Cell (2012) 2.03
Planarian regeneration involves distinct stem cell responses to wounds and tissue absence. Dev Biol (2010) 1.93
A wound-induced Wnt expression program controls planarian regeneration polarity. Proc Natl Acad Sci U S A (2009) 1.88
Polarized notum activation at wounds inhibits Wnt function to promote planarian head regeneration. Science (2011) 1.79
A regulatory program for excretory system regeneration in planarians. Development (2011) 1.43
A molecular wound response program associated with regeneration initiation in planarians. Genes Dev (2012) 1.41
The Mi-2-like Smed-CHD4 gene is required for stem cell differentiation in the planarian Schmidtea mediterranea. Development (2010) 1.40
The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis. Dev Biol (2009) 1.38
dlx and sp6-9 Control optic cup regeneration in a prototypic eye. PLoS Genet (2011) 1.29
Muscle cells provide instructions for planarian regeneration. Cell Rep (2013) 1.13
A Bmp/Admp regulatory circuit controls maintenance and regeneration of dorsal-ventral polarity in planarians. Curr Biol (2011) 1.12
Tissue absence initiates regeneration through follistatin-mediated inhibition of activin signaling. Elife (2013) 0.98
pbx is required for pole and eye regeneration in planarians. Development (2013) 0.95