Published in Cell Death Differ on August 17, 2012
Nucleolar stress with and without p53. Nucleus (2014) 1.13
The p53 control of apoptosis and proliferation: lessons from Drosophila. Apoptosis (2014) 0.93
Apoptotic mechanisms during competition of ribosomal protein mutant cells: roles of the initiator caspases Dronc and Dream/Strica. Cell Death Differ (2015) 0.92
ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration. PLoS Genet (2015) 0.92
Spreading the word: non-autonomous effects of apoptosis during development, regeneration and disease. Development (2015) 0.84
Low levels of p53 protein and chromatin silencing of p53 target genes repress apoptosis in Drosophila endocycling cells. PLoS Genet (2014) 0.83
p53 on the crossroad between regeneration and cancer. Cell Death Differ (2016) 0.80
The function of Drosophila p53 isoforms in apoptosis. Cell Death Differ (2015) 0.77
Expression of dengue virus NS3 protein in Drosophila alters its susceptibility to infection. Fly (Austin) (2015) 0.77
p53 isoforms change p53 paradigm. Mol Cell Oncol (2014) 0.76
Non-autonomous consequences of cell death and other perks of being metazoan. AIMS Genet (2015) 0.76
Protruding structures on caterpillars are controlled by ectopic Wnt1 expression. PLoS One (2015) 0.75
Rb-mediated apoptosis or proliferation: It's up to JNK. Cell Cycle (2016) 0.75
p53 in health and disease. Nat Rev Mol Cell Biol (2007) 11.33
p53 isoforms can regulate p53 transcriptional activity. Genes Dev (2005) 6.76
Genetic control of programmed cell death in Drosophila. Science (1994) 6.08
Cytoplasmic functions of the tumour suppressor p53. Nature (2009) 5.23
Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev Cell (2004) 4.71
Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nat Med (2011) 4.68
Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev (2002) 4.21
Drosophila p53 binds a damage response element at the reaper locus. Cell (2000) 3.92
Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell (2000) 3.41
Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila. Development (2004) 2.79
Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol Cell Biol (2004) 2.75
p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev (2009) 2.57
Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Curr Biol (2004) 2.57
Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity. Curr Biol (2006) 2.51
DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53. Oncogene (2002) 2.27
Distinct mechanisms of apoptosis-induced compensatory proliferation in proliferating and differentiating tissues in the Drosophila eye. Dev Cell (2008) 2.21
p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol (2010) 2.16
The p53 family: guardians of maternal reproduction. Nat Rev Mol Cell Biol (2011) 2.13
Apoptosis-induced compensatory proliferation. The Cell is dead. Long live the Cell! Trends Cell Biol (2008) 2.12
Identification and characterization of a p53 homologue in Drosophila melanogaster. Proc Natl Acad Sci U S A (2000) 2.04
Apoptosis, stem cells, and tissue regeneration. Sci Signal (2010) 1.95
The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc. Development (2009) 1.82
DRONC coordinates cell death and compensatory proliferation. Mol Cell Biol (2006) 1.75
Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ (2011) 1.74
Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis. Development (2005) 1.65
ER stress protects from retinal degeneration. EMBO J (2009) 1.47
Creating transgenic Drosophila by microinjecting the site-specific phiC31 integrase mRNA and a transgene-containing donor plasmid. Nat Protoc (2007) 1.47
p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage. Cell Death Differ (2010) 1.36
A dp53/JNK-dependant feedback amplification loop is essential for the apoptotic response to stress in Drosophila. Cell Death Differ (2011) 1.32
Meiotic recombination provokes functional activation of the p53 regulatory network. Science (2010) 1.27
E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage. PLoS Genet (2008) 1.21
The function of engrailed and the specification of Drosophila wing pattern. Development (1995) 1.20
Phylogeny and function of the invertebrate p53 superfamily. Cold Spring Harb Perspect Biol (2010) 1.19
The intestinal epithelium compensates for p53-mediated cell death and guarantees organismal survival. Cell Death Differ (2008) 1.17
Compensatory proliferation and apoptosis-induced proliferation: a need for clarification. Cell Death Differ (2012) 1.15
Mitogenic signaling from apoptotic cells in Drosophila. Dev Growth Differ (2011) 1.14
Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response. EMBO J (2003) 1.13
A green fluorescent protein enhancer trap screen in Drosophila photoreceptor cells. Mech Dev (2000) 1.13
Metabolic control of G1-S transition: cyclin E degradation by p53-induced activation of the ubiquitin-proteasome system. J Cell Biol (2010) 1.10
Programmed cell death of primordial germ cells in Drosophila is regulated by p53 and the Outsiders monocarboxylate transporter. Development (2007) 1.08
Dual roles of Drosophila p53 in cell death and cell differentiation. Cell Death Differ (2009) 1.05
Normal regulation of Rbf1/E2f1 target genes in Drosophila type 1 protein phosphatase mutants. Dev Dyn (2007) 0.89
The NAB-Brk signal bifurcates at JNK to independently induce apoptosis and compensatory proliferation. J Biol Chem (2011) 0.87
It's all about balance: p53 and aging. Aging (Albany NY) (2009) 0.86
Injury-induced activation of the MAPK/CREB pathway triggers apoptosis-induced compensatory proliferation in hydra head regeneration. Dev Growth Differ (2011) 0.82
The sequence of the human genome. Science (2001) 101.55
AcrAB efflux pump plays a major role in the antibiotic resistance phenotype of Escherichia coli multiple-antibiotic-resistance (Mar) mutants. J Bacteriol (1996) 8.50
TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem Biophys Res Commun (1999) 6.33
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell (2000) 4.48
Role of efflux pump(s) in intrinsic resistance of Pseudomonas aeruginosa: active efflux as a contributing factor to beta-lactam resistance. Antimicrob Agents Chemother (1994) 4.43
Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal. Tob Control (2008) 4.37
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene (2007) 4.27
p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death Differ (2006) 3.49
Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein. Cell (1997) 3.49
Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature (1999) 3.06
Rituximab (anti-CD20 monoclonal antibody) for the treatment of patients with relapsing or refractory aggressive lymphoma: a multicenter phase II study. Blood (1998) 2.83
Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy. Neurology (2012) 2.56
Tumor therapy with targeted atomic nanogenerators. Science (2001) 2.48
Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes. Immunogenetics (1992) 2.45
Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia (2011) 2.43
Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology. Mol Psychiatry (2013) 2.25
AcrD of Escherichia coli is an aminoglycoside efflux pump. J Bacteriol (2000) 2.24
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol Cell Biol (1996) 2.20
Impact of anaesthetics and surgery on neurodevelopment: an update. Br J Anaesth (2013) 1.99
Control of the nuclear localization of Extradenticle by competing nuclear import and export signals. Genes Dev (1999) 1.97
Recent advances in p53 research: an interdisciplinary perspective. Cancer Gene Ther (2008) 1.88
Hepatocellular carcinoma: from gene to public health. J Natl Cancer Inst (1997) 1.86
An alpha-particle emitting antibody ([213Bi]J591) for radioimmunotherapy of prostate cancer. Cancer Res (2000) 1.85
Genetic alterations in esophageal cancer and their relevance to etiology and pathogenesis: a review. Int J Cancer (1996) 1.82
Presence on a human melanoma of multiple antigens recognized by autologous CTL. Int J Cancer (1989) 1.80
New approaches to understanding p53 gene tumor mutation spectra. Mutat Res (1999) 1.75
Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death Differ (2011) 1.74
Genetic steps in the development of squamous cell carcinoma of the esophagus. Mutat Res (2000) 1.73
Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma. Br J Cancer (2008) 1.59
Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells. Int J Cancer (1992) 1.57
Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading in mice. J Periodontol (2008) 1.56
Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription. Genes Dev (1994) 1.53
Factors influencing survival rate in adenoid cystic carcinoma of the salivary glands. Int J Oral Maxillofac Surg (1997) 1.52
TP53: a key gene in human cancer. Biochimie (2002) 1.50
Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. Acta Anaesthesiol Scand (2009) 1.50
IARC p53 mutation database: a relational database to compile and analyze p53 mutations in human tumors and cell lines. International Agency for Research on Cancer. Hum Mutat (1999) 1.48
Human B cell development. I. Phenotypic differences of B lymphocytes in the bone marrow and peripheral lymphoid tissue. J Immunol (1985) 1.41
Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies. Cancer Gene Ther (2010) 1.41
Xenon exposure in the neonatal rat brain: effects on genes that regulate apoptosis. Minerva Anestesiol (2011) 1.39
Differences in the antigens recognized by cytolytic T cells on two successive metastases of a melanoma patient are consistent with immune selection. Eur J Immunol (1995) 1.39
p53 directly transactivates Δ133p53α, regulating cell fate outcome in response to DNA damage. Cell Death Differ (2010) 1.36
The multidisciplinary management of gastrointestinal cancer. Epidemiology of oesophagogastric cancer. Best Pract Res Clin Gastroenterol (2007) 1.36
Properties of the six isoforms of p63: p53-like regulation in response to genotoxic stress and cross talk with DeltaNp73. Carcinogenesis (2007) 1.34
Antibodies to capsular polysaccharides of group B Streptococcus in pregnant Canadian women: relationship to colonization status and infection in the neonate. J Infect Dis (2001) 1.33
Up-regulation of Fas (APO-1/CD95) ligand and down-regulation of Fas expression in human esophageal cancer. Cancer Res (1998) 1.29
Long-term outcomes after allogeneic stem cell transplantation for children with hematological malignancies. Bone Marrow Transplant (2007) 1.28
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. Br J Anaesth (2013) 1.26
The graft-versus-leukemia effect is mainly restricted to NIH-defined chronic graft-versus-host disease after reduced intensity conditioning before allogeneic stem cell transplantation. Leukemia (2010) 1.26
p53 regulates the transcription of its Delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. Oncogene (2010) 1.26
Genotoxic and non-genotoxic pathways of p53 induction. Cancer Lett (2001) 1.25
Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. Acta Anaesthesiol Scand (2011) 1.25
Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Leukemia (2003) 1.23
Dynamics of DNA supercoiling by transcription in Escherichia coli. Proc Natl Acad Sci U S A (1992) 1.23
Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia. J Natl Cancer Inst (2000) 1.23
Allogeneic stem cell transplantation for older advanced MDS patients: improved survival with young unrelated donor in comparison with HLA-identical siblings. Leukemia (2012) 1.23
Overweight, obesity and risk of premenopausal breast cancer according to ethnicity: a systematic review and dose-response meta-analysis. Obes Rev (2013) 1.23
Identification of cancer stem cell-like cells from human epithelial ovarian carcinoma cell line. Cell Mol Life Sci (2010) 1.21
Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells. Oncogene (2000) 1.21
Noradrenergic suppression of synaptic transmission may influence cortical signal-to-noise ratio. J Neurophysiol (1997) 1.20
Regulation of p53 by metal ions and by antioxidants: dithiocarbamate down-regulates p53 DNA-binding activity by increasing the intracellular level of copper. Mol Cell Biol (1997) 1.19
A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila. Genes Dev (1997) 1.19
Etoposide in acute nonlymphocytic leukemia. Australian Leukemia Study Group. Blood (1990) 1.17
Comparison of conditioning regimens of various intensities for allogeneic hematopoietic SCT using HLA-identical sibling donors in AML and MDS with <10% BM blasts: a report from EBMT. Bone Marrow Transplant (2012) 1.16
Stress-induced transcription of the clusterin/apoJ gene. Biochem J (1997) 1.16
Switching the in vivo specificity of a minimal Hox-responsive element. Development (1997) 1.16
Compensatory proliferation and apoptosis-induced proliferation: a need for clarification. Cell Death Differ (2012) 1.15
Inactivation of the p53 protein in cell lines derived from human esophageal cancers. Int J Cancer (1997) 1.13
Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB. Oncogene (2006) 1.13
Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells. J Biol Chem (1999) 1.12
Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran. Oncogene (2001) 1.12
BTG gene expression in the p53-dependent and -independent cellular response to DNA damage. Mol Carcinog (2000) 1.12
Determination of glucose in biologic fluids with an automated enzymatic procedure. Clin Chem (1965) 1.11
cDNA cloning and expression of an apoptosis-related gene, humanTFAR15 gene. Sci China C Life Sci (1999) 1.11
Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein. Cancer Res (1997) 1.11
Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa. J Viral Hepat (2009) 1.10
TP53 PIN3 and MDM2 SNP309 polymorphisms as genetic modifiers in the Li-Fraumeni syndrome: impact on age at first diagnosis. J Med Genet (2009) 1.10
Mutant p53 reactivation by PRIMA-1MET induces multiple signaling pathways converging on apoptosis. Oncogene (2009) 1.10
p53 mutation, deprivation and poor prognosis in primary breast cancer. Br J Cancer (2010) 1.10
Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses. Am J Physiol Heart Circ Physiol (2001) 1.09
Nuclear translocation of PDCD5 (TFAR19): an early signal for apoptosis? FEBS Lett (2001) 1.09
The Leishmania GDP-mannose transporter is an autonomous, multi-specific, hexameric complex of LPG2 subunits. Biochemistry (2000) 1.09
Synthesis and evaluation of novel bifunctional chelating agents based on 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid for radiolabeling proteins. Nucl Med Biol (2003) 1.08
Inhibition of ovarian cancer metastasis by adeno-associated virus-mediated gene transfer of nm23H1 in an orthotopic implantation model. Cancer Gene Ther (2006) 1.07
Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling. EMBO J (1997) 1.06
Impact of comorbidity indexes on non-relapse mortality. Leukemia (2008) 1.06
Oral contraceptives and carbohydrate metabolism. Am J Obstet Gynecol (1968) 1.05
TP53, EGFR, and KRAS mutations in relation to VHL inactivation and lifestyle risk factors in renal-cell carcinoma from central and eastern Europe. Cancer Lett (2010) 1.05
A pharmacoproteomic approach implicates eukaryotic elongation factor 2 kinase in ER stress-induced cell death. Cell Death Differ (2008) 1.05
Response of LNCaP spheroids after treatment with an alpha-particle emitter (213Bi)-labeled anti-prostate-specific membrane antigen antibody (J591). Cancer Res (2001) 1.04
Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions. Cancer Res (2001) 1.04
The effect of coffee consumption on serum lipids: a meta-analysis of randomized controlled trials. Eur J Clin Nutr (2012) 1.04
Pneumocystis carinii pneumonia in critically ill patients with malignancy: a descriptive study. Clin Infect Dis (2002) 1.04
Diverse p63 and p73 isoforms regulate Δ133p53 expression through modulation of the internal TP53 promoter activity. Cell Death Differ (2011) 1.03