Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial.

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Published in Lancet on August 18, 2012

Authors

Ian D Pavord1, Stephanie Korn, Peter Howarth, Eugene R Bleecker, Roland Buhl, Oliver N Keene, Hector Ortega, Pascal Chanez

Author Affiliations

1: Institute for Lung Health, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK. ian.pavord@uhl-tr.nhs.uk

Associated clinical trials:

Dose Ranging Efficacy And Safety With Mepolizumab in Severe Asthma (DREAM) | NCT01000506

Anti-Interleukin-5 (IL5) Monoclonal Antibody (MAb) in Prednisone-dependent Eosinophilic Asthma | NCT02559791

Allogeneic Human Cells (hMSC) Via Intravenous Delivery in Patients With Mild Asthma (ASTEC) | NCT03137199

Exploring Asthma Exacerbations in Mepolizumab Treated Patients | NCT03324230

Wessex Asthma Cohort of Difficult Asthma (WATCH) | NCT03996590

Phenotyping Circulating and Lung Resident Eosinophils in Severe Asthma (P-CLESA) (P-CLESA) | NCT04463836

Functional Lung MRI for Early Treatment Response Assessment for Patients With Eosinophilic Asthma (FUNLUM) | NCT04512521

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