Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus.

PubWeight™: 1.64‹?› | Rank: Top 3%

🔗 View Article (PMC 3472468)

Published in Physiol Genomics on August 28, 2012

Authors

Christopher G Vecsey1, Lucia Peixoto, Jennifer H K Choi, Mathieu Wimmer, Devan Jaganath, Pepe J Hernandez, Jennifer Blackwell, Karuna Meda, Alan J Park, Sridhar Hannenhalli, Ted Abel

Author Affiliations

1: Department of Biology, Brandeis University, Waltham, Massachusetts, USA.

Articles citing this

About sleep's role in memory. Physiol Rev (2013) 3.35

Sleep, plasticity and memory from molecules to whole-brain networks. Curr Biol (2013) 1.39

Effects of sleep and wake on oligodendrocytes and their precursors. J Neurosci (2013) 1.18

Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues Clin Neurosci (2014) 1.15

Sleep, clocks, and synaptic plasticity. Trends Neurosci (2014) 1.01

Sleep deprivation during a specific 3-hour time window post-training impairs hippocampal synaptic plasticity and memory. Neurobiol Learn Mem (2013) 0.96

CA1 hippocampal network activity changes during sleep-dependent memory consolidation. Front Syst Neurosci (2014) 0.90

Set and setting: how behavioral state regulates sensory function and plasticity. Neurobiol Learn Mem (2013) 0.89

DAF-16/FOXO regulates homeostasis of essential sleep-like behavior during larval transitions in C. elegans. Curr Biol (2013) 0.89

Sleep, plasticity and the pathophysiology of neurodevelopmental disorders: the potential roles of protein synthesis and other cellular processes. Brain Sci (2014) 0.83

Circadian dysregulation of clock genes: clues to rapid treatments in major depressive disorder. Mol Psychiatry (2014) 0.83

The impact of sleep loss on hippocampal function. Learn Mem (2013) 0.82

Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis. Sci Signal (2016) 0.81

Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress. Front Behav Neurosci (2014) 0.81

Effects of Chronic Sleep Restriction during Early Adolescence on the Adult Pattern of Connectivity of Mouse Secondary Motor Cortex. eNeuro (2016) 0.78

Sleep and oligodendrocyte functions. Curr Sleep Med Rep (2015) 0.77

The sleep-deprived hippocampus: a loss in translation. Physiol Genomics (2012) 0.76

Effects of acute sleep deprivation on motor and reversal learning in mice. Neurobiol Learn Mem (2014) 0.76

Circadian Regulation of Synaptic Plasticity. Biology (Basel) (2016) 0.76

Effects of sleep deprivation and aging on long-term and remote memory in mice. Learn Mem (2015) 0.76

The tired hippocampus: the molecular impact of sleep deprivation on hippocampal function. Curr Opin Neurobiol (2017) 0.75

Contextual fear conditioning induces differential alternative splicing. Neurobiol Learn Mem (2016) 0.75

Removal of unwanted variation reveals novel patterns of gene expression linked to sleep homeostasis in murine cortex. BMC Genomics (2016) 0.75

Transcriptome Analysis Reveals Altered Expression of Memory and Neurotransmission Associated Genes in the REM Sleep Deprived Rat Brain. Front Mol Neurosci (2017) 0.75

Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction. Neurochem Int (2015) 0.75

Linking Network Activity to Synaptic Plasticity during Sleep: Hypotheses and Recent Data. Front Neural Circuits (2017) 0.75

Articles cited by this

Bioconductor: open software development for computational biology and bioinformatics. Genome Biol (2004) 143.19

DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79

TOR signaling in growth and metabolism. Cell (2006) 35.29

Controlling the false discovery rate in behavior genetics research. Behav Brain Res (2001) 21.82

The metabolic consequences of sleep deprivation. Sleep Med Rev (2007) 6.07

mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci (2009) 5.04

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci (2007) 5.02

Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med (2007) 4.23

Sleep duration as a risk factor for diabetes incidence in a large U.S. sample. Sleep (2007) 4.14

Associations between sleep loss and increased risk of obesity and diabetes. Ann N Y Acad Sci (2008) 4.01

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem (2001) 3.81

Translational regulatory mechanisms in persistent forms of synaptic plasticity. Neuron (2004) 3.64

Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence. Nat Neurosci (2008) 3.03

Extensive and divergent effects of sleep and wakefulness on brain gene expression. Neuron (2004) 2.95

Sleep enhances plasticity in the developing visual cortex. Neuron (2001) 2.93

Molecular mechanisms of memory acquisition, consolidation and retrieval. Curr Opin Neurobiol (2001) 2.78

Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem (1999) 2.72

Sleep loss, learning capacity and academic performance. Sleep Med Rev (2006) 2.60

The homeostatic regulation of sleep need is under genetic control. J Neurosci (2001) 2.56

Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease. Nat Rev Neurosci (2010) 2.49

hnRNP proteins and splicing control. Adv Exp Med Biol (2007) 2.39

Sleep and the epidemic of obesity in children and adults. Eur J Endocrinol (2008) 2.38

Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning. Learn Mem (2003) 2.34

Elements of a neurobiological theory of the hippocampus: the role of activity-dependent synaptic plasticity in memory. Philos Trans R Soc Lond B Biol Sci (2003) 2.34

Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons. J Neurosci (2003) 2.19

Homer1a is a core brain molecular correlate of sleep loss. Proc Natl Acad Sci U S A (2007) 2.13

Sleep duration as a risk factor for incident type 2 diabetes in a multiethnic cohort. Ann Epidemiol (2009) 2.07

Identification of transcription factor binding sites in the human genome sequence. Mamm Genome (2002) 2.00

A single night of partial sleep deprivation induces insulin resistance in multiple metabolic pathways in healthy subjects. J Clin Endocrinol Metab (2010) 1.98

Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons. J Neurosci (2006) 1.94

Macromolecule biosynthesis: a key function of sleep. Physiol Genomics (2007) 1.93

Sleep and brain energy levels: ATP changes during sleep. J Neurosci (2010) 1.88

Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis. Proc Natl Acad Sci U S A (2005) 1.85

Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: empirical data and simulations. Brain Res (2000) 1.83

Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes Rev (2009) 1.83

Sleep deprivation impairs cAMP signalling in the hippocampus. Nature (2009) 1.83

Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron (2008) 1.80

Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis. Sleep (2010) 1.64

Two time periods of hippocampal mRNA synthesis are required for memory consolidation of fear-motivated learning. J Neurosci (2002) 1.61

Insufficient sleep reversibly alters bidirectional synaptic plasticity and NMDA receptor function. J Neurosci (2006) 1.61

Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway. J Neurosci (2006) 1.59

Metabolic, endocrine, and immune consequences of sleep deprivation. Open Respir Med J (2011) 1.57

Insufficient sleep--a population-based study in adults. Sleep (2001) 1.48

Evidence for a paradoxical sleep window for place learning in the Morris water maze. Physiol Behav (1996) 1.45

Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine. Mol Psychiatry (2006) 1.42

Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage. Proc Natl Acad Sci U S A (2011) 1.41

mTOR signaling in the hippocampus is necessary for memory formation. Neurobiol Learn Mem (2006) 1.40

LTP maintenance and its protein synthesis-dependence. Neurobiol Learn Mem (2007) 1.39

The role of protein synthesis in memory consolidation: progress amid decades of debate. Neurobiol Learn Mem (2007) 1.39

Sleep deprivation impairs object recognition in mice. Neurobiol Learn Mem (2006) 1.38

Sleep deprivation induces the unfolded protein response in mouse cerebral cortex. J Neurochem (2005) 1.33

Positive correlations between cerebral protein synthesis rates and deep sleep in Macaca mulatta. Eur J Neurosci (1997) 1.32

Sleep deprivation impairs spatial memory and decreases extracellular signal-regulated kinase phosphorylation in the hippocampus. Brain Res (2004) 1.28

Gene expression in the rat brain during sleep deprivation and recovery sleep: an Affymetrix GeneChip study. Neuroscience (2005) 1.27

Rates of cerebral protein synthesis are linked to slow wave sleep in the rat. Physiol Behav (1990) 1.26

Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA. J Biol Chem (2001) 1.25

Protein synthesis in eukaryotes: the growing biological relevance of cap-independent translation initiation. Biol Res (2005) 1.24

Paradoxical (REM) sleep deprivation causes a large and rapidly reversible decrease in long-term potentiation, synaptic transmission, glutamate receptor protein levels, and ERK/MAPK activation in the dorsal hippocampus. Sleep (2009) 1.24

Multiple mechanisms limit the duration of wakefulness in Drosophila brain. Physiol Genomics (2006) 1.23

Sleep and memory: a molecular perspective. Trends Neurosci (2001) 1.23

Protein synthesis during sleep consolidates cortical plasticity in vivo. Curr Biol (2012) 1.21

Proteomic analysis of the effects and interactions of sleep deprivation and aging in mouse cerebral cortex. J Neurochem (2007) 1.20

TOR on the brain. Exp Gerontol (2010) 1.18

Suppression of hippocampal plasticity-related gene expression by sleep deprivation in rats. J Physiol (2006) 1.17

Two isoforms of the cold-inducible mRNA-binding protein RBM3 localize to dendrites and promote translation. J Neurochem (2007) 1.14

Sleep to find your way: the role of sleep in the consolidation of memory for navigation in humans. Hippocampus (2008) 1.14

Changes in components of energy regulation in mouse cortex with increases in wakefulness. Sleep (2010) 1.13

Molecular and anatomical signatures of sleep deprivation in the mouse brain. Front Neurosci (2010) 1.12

Sleep deprivation impairs spatial working memory and reduces hippocampal AMPA receptor phosphorylation. J Sleep Res (2009) 1.11

Sleep deprivation by the "flower pot" technique and spatial reference memory. Physiol Behav (1997) 1.08

Sleep deprivation impairs hippocampus-mediated contextual learning but not amygdala-mediated cued learning in rats. Eur J Neurosci (2004) 1.07

Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb Cortex (2008) 1.05

A social conflict increases EEG slow-wave activity during subsequent sleep. Physiol Behav (2001) 1.00

Locus ceruleus control of state-dependent gene expression. J Neurosci (2004) 1.00

Hippocampal cell proliferation across the day: increase by running wheel activity, but no effect of sleep and wakefulness. Behav Brain Res (2005) 1.00

The role of sleep in the consolidation of route learning in humans: a behavioural study. Brain Res Bull (2006) 1.00

Sleep deprivation-induced protein changes in basal forebrain: implications for synaptic plasticity. J Neurosci Res (2005) 0.99

Conditions that affect sleep alter the expression of molecules associated with synaptic plasticity. Am J Physiol Regul Integr Comp Physiol (2001) 0.98

Methods for proteomics in neuroscience. Prog Brain Res (2006) 0.98

The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity. Cell Signal (2012) 0.96

Effects of social stimuli on sleep in mice: non-rapid-eye-movement (NREM) sleep is promoted by aggressive interaction but not by sexual interaction. Brain Res (2001) 0.94

Central AMPK contributes to sleep homeostasis in mice. Neuropharmacology (2009) 0.93

Computational analysis of gene regulation in animal sleep deprivation. Physiol Genomics (2010) 0.88

Proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation. Proteome Sci (2008) 0.87

A molecular basis for interactions between sleep and memory. Sleep Med Clin (2011) 0.83

Post-transcriptional control of the MCT-1-associated protein DENR/DRP by RNA-binding protein AUF1. Cancer Genomics Proteomics (2007) 0.82

NGFI-A expression in the rat brain after sleep deprivation. Brain Res Mol Brain Res (1997) 0.81

Gene expression during memory formation. Neurotox Res (2004) 0.80

Articles by these authors

Whole-genome shotgun assembly and comparison of human genome assemblies. Proc Natl Acad Sci U S A (2004) 6.08

A role for lateral hypothalamic orexin neurons in reward seeking. Nature (2005) 5.41

Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss. Neuron (2009) 5.22

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci (2007) 5.02

Genome-wide analysis of retroviral DNA integration. Nat Rev Microbiol (2005) 3.98

Retroviral DNA integration: viral and cellular determinants of target-site selection. PLoS Pathog (2006) 3.67

Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. Learn Mem (2005) 3.37

Selection of target sites for mobile DNA integration in the human genome. PLoS Comput Biol (2006) 3.21

Highlights from the 5th International Society for Computational Biology Student Council Symposium at the 17th Annual International Conference on Intelligent Systems for Molecular Biology and the 8th European Conference on Computational Biology. BMC Bioinformatics (2009) 2.84

Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem (2005) 2.47

Sleep deprivation selectively impairs memory consolidation for contextual fear conditioning. Learn Mem (2003) 2.34

A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes. Learn Mem (2006) 2.11

Mastectomy scars following breast reconstruction: should routine histologic analysis be performed? Plast Reconstr Surg (2009) 2.08

Identification of transcription factor binding sites in the human genome sequence. Mamm Genome (2002) 2.00

Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial. Ann Intern Med (2013) 1.97

Sleep deprivation impairs cAMP signalling in the hippocampus. Nature (2009) 1.83

Lateral hypothalamic orexin neurons are critically involved in learning to associate an environment with morphine reward. Behav Brain Res (2007) 1.73

Online social networking for HIV education and prevention: a mixed-methods analysis. Sex Transm Dis (2013) 1.72

Post-training reversible inactivation of the hippocampus enhances novel object recognition memory. Learn Mem (2010) 1.65

Behavioral impairments caused by injections of the protein synthesis inhibitor anisomycin after contextual retrieval reverse with time. Proc Natl Acad Sci U S A (2004) 1.64

The mouse: genetics meets behaviour. Nat Rev Genet (2002) 1.62

Long-term effects of culture of preimplantation mouse embryos on behavior. Proc Natl Acad Sci U S A (2004) 1.57

The role of histone acetylation in memory formation and cognitive impairments. Neuropsychopharmacology (2012) 1.53

Transgenic mice expressing an inhibitory truncated form of p300 exhibit long-term memory deficits. Learn Mem (2007) 1.48

Gene coexpression network topology of cardiac development, hypertrophy, and failure. Circ Cardiovasc Genet (2010) 1.46

The role of protein synthesis in memory consolidation: progress amid decades of debate. Neurobiol Learn Mem (2007) 1.39

GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development (2007) 1.39

CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features. Genome Biol (2009) 1.38

Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell (2010) 1.38

Genetic evidence for a role of CREB in sustained cortical arousal. J Neurophysiol (2003) 1.37

Gene profiling of human adipose tissue during evoked inflammation in vivo. Diabetes (2009) 1.34

Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Ann Neurol (2010) 1.34

Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch. Neuron (2013) 1.34

Maternal depletion of CTCF reveals multiple functions during oocyte and preimplantation embryo development. Development (2008) 1.32

Protein synthesis is required for the enhancement of long-term potentiation and long-term memory by spaced training. J Neurophysiol (2002) 1.30

Astrocyte-derived adenosine and A1 receptor activity contribute to sleep loss-induced deficits in hippocampal synaptic plasticity and memory in mice. J Neurosci (2011) 1.29

Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation. Nucleic Acids Res (2007) 1.28

Behavioral and neurochemical alterations in mice lacking the RNA-binding protein translin. J Neurosci (2006) 1.25

Neuregulin 1 transgenic mice display reduced mismatch negativity, contextual fear conditioning and social interactions. Brain Res (2009) 1.24

Adrenergic signaling plays a critical role in the maintenance of waking and in the regulation of REM sleep. J Neurophysiol (2004) 1.23

Combinatorial chromatin modifications and memory storage: a code for memory? Learn Mem (2006) 1.23

The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP components. Neurochem Res (2004) 1.23

Functional analysis of Hes-1 in preadipocytes. Mol Endocrinol (2005) 1.21

A loss of function allele for murine Staufen1 leads to impairment of dendritic Staufen1-RNP delivery and dendritic spine morphogenesis. Proc Natl Acad Sci U S A (2008) 1.21

Mice deficient for testis-brain RNA-binding protein exhibit a coordinate loss of TRAX, reduced fertility, altered gene expression in the brain, and behavioral changes. Mol Cell Biol (2003) 1.19

Young proteins experience more variable selection pressures than old proteins. Genome Res (2010) 1.19

Temporal spacing of synaptic stimulation critically modulates the dependence of LTP on cyclic AMP-dependent protein kinase. Hippocampus (2003) 1.18

Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments. Learn Mem (2011) 1.16

Constitutive activation of Galphas within forebrain neurons causes deficits in sensorimotor gating because of PKA-dependent decreases in cAMP. Neuropsychopharmacology (2006) 1.15

Differential transcriptional response to nonassociative and associative components of classical fear conditioning in the amygdala and hippocampus. Learn Mem (2006) 1.14

Regulation of lung endoderm progenitor cell behavior by miR302/367. Development (2011) 1.14

Post-training intrahippocampal inhibition of class I histone deacetylases enhances long-term object-location memory. Learn Mem (2011) 1.14

Behavioral epigenetics. Ann N Y Acad Sci (2011) 1.14

Genetic and physiological activation of osmosensitive gene expression mimics transcriptional signatures of pathogen infection in C. elegans. PLoS One (2010) 1.13

Transgenic inhibition of neuronal protein kinase A activity facilitates fear extinction. J Neurosci (2006) 1.12

A mammalian promoter model links cis elements to genetic networks. Biochem Biophys Res Commun (2006) 1.11

Project HOPE: online social network changes in an HIV prevention randomized controlled trial for African American and Latino men who have sex with men. Am J Public Health (2014) 1.11

Deficits in spatial memory correlate with modified {gamma}-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus. Proc Natl Acad Sci U S A (2009) 1.09

Glutamate-mediated plasticity in corticostriatal networks: role in adaptive motor learning. Ann N Y Acad Sci (2003) 1.09

Why transcription factor binding sites are ten nucleotides long. Genetics (2012) 1.07

Quantification of brain maturation and growth patterns in C57BL/6J mice via computational neuroanatomy of diffusion tensor images. Cereb Cortex (2008) 1.06

Low sociability is associated with reduced size of the corpus callosum in the BALB/cJ inbred mouse strain. Brain Res (2008) 1.05

Genome-wide expression profiling and bioinformatics analysis of diurnally regulated genes in the mouse prefrontal cortex. Genome Biol (2007) 1.05

NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors. J Clin Invest (2012) 1.04

Genetic disruption of protein kinase A anchoring reveals a role for compartmentalized kinase signaling in theta-burst long-term potentiation and spatial memory. J Neurosci (2007) 1.04

Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains. Brain Res (2003) 1.03

Extinction, renewal, and spontaneous recovery of a spatial preference in the water maze. Behav Neurosci (2003) 1.03

The role of NR4A transcription factors in memory formation. Brain Res Bull (2011) 1.03

In vivo turnover of tau and APP metabolites in the brains of wild-type and Tg2576 mice: greater stability of sAPP in the beta-amyloid depositing mice. PLoS One (2009) 1.02

Differential role for CBP and p300 CREB-binding domain in motor skill learning. Behav Neurosci (2006) 1.02

Reversal of impaired hippocampal long-term potentiation and contextual fear memory deficits in Angelman syndrome model mice by ErbB inhibitors. Biol Psychiatry (2012) 1.02

Impaired rapid eye movement sleep in the Tg2576 APP murine model of Alzheimer's disease with injury to pedunculopontine cholinergic neurons. Am J Pathol (2005) 1.02

Genetic approaches to the study of synaptic plasticity and memory storage. CNS Spectr (2003) 1.01

Effects of chronic olanzapine and haloperidol differ on the mouse N1 auditory evoked potential. Neuropsychopharmacology (2004) 1.00

Genome-wide analysis of natural selection on human cis-elements. PLoS One (2008) 1.00

Temporal sensitivity of protein kinase a activation in late-phase long term potentiation. PLoS Comput Biol (2010) 0.99

Functional diversification of paralogous transcription factors via divergence in DNA binding site motif and in expression. PLoS One (2008) 0.99

Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiation. Eur J Cell Biol (2006) 0.99

Induction of neuronal vascular endothelial growth factor expression by cAMP in the dentate gyrus of the hippocampus is required for antidepressant-like behaviors. J Neurosci (2009) 0.99

Aging impairs hippocampus-dependent long-term memory for object location in mice. Neurobiol Aging (2011) 0.99

Metaplasticity of the late-phase of long-term potentiation: a critical role for protein kinase A in synaptic tagging. Eur J Neurosci (2006) 0.98

Feasibility of using social networking technologies for health research among men who have sex with men: a mixed methods study. Am J Mens Health (2013) 0.98

The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity. Cell Signal (2012) 0.96

Recurring genomic breaks in independent lineages support genomic fragility. BMC Evol Biol (2006) 0.96

Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure. Circ Cardiovasc Genet (2008) 0.96

Gadd45b knockout mice exhibit selective deficits in hippocampus-dependent long-term memory. Learn Mem (2012) 0.96

Genetic and pharmacological demonstration of a role for cyclic AMP-dependent protein kinase-mediated suppression of protein phosphatases in gating the expression of late LTP. Eur J Neurosci (2002) 0.95

MetaProm: a neural network based meta-predictor for alternative human promoter prediction. BMC Genomics (2007) 0.94

Evidence for coregulation of myocardial gene expression by MEF2 and NFAT in human heart failure. Circ Cardiovasc Genet (2009) 0.94

Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. J Neurosci (2012) 0.94

Sensorimotor gating deficits in transgenic mice expressing a constitutively active form of Gs alpha. Neuropsychopharmacology (2004) 0.93

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians. Clin Endocrinol (Oxf) (2008) 0.93

Enhancement of presynaptic glutamate release and persistent inflammatory pain by increasing neuronal cAMP in the anterior cingulate cortex. Mol Pain (2008) 0.92

Intrinsically disordered proteins and conformational noise: implications in cancer. Cell Cycle (2012) 0.92