Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMC 3479325)

Published in Stroke on August 28, 2012

Authors

Guido J Falcone1, Alessandro Biffi, William J Devan, Jeremiasz M Jagiella, Helena Schmidt, Brett Kissela, Björn M Hansen, Jordi Jimenez-Conde, Eva Giralt-Steinhauer, Roberto Elosua, Elisa Cuadrado-Godia, Carolina Soriano, Alison M Ayres, Kristin Schwab, Joanna Pera, Andrzej Urbanik, Natalia S Rost, Joshua N Goldstein, Anand Viswanathan, Alexander Pichler, Christian Enzinger, Bo Norrving, David L Tirschwell, Magdy Selim, Devin L Brown, Scott L Silliman, Bradford B Worrall, James F Meschia, Chelsea S Kidwell, Joan Montaner, Israel Fernandez-Cadenas, Pilar Delgado, Joseph P Broderick, Steven M Greenberg, Jaume Roquer, Arne Lindgren, Agnieszka Slowik, Reinhold Schmidt, Matthew L Flaherty, Dawn O Kleindorfer, Carl D Langefeld, Daniel Woo, Jonathan Rosand, International Stroke Genetics Consortium

Author Affiliations

1: Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, and Department of Epidemiology, Harvard School of Public Health, 185 Cambridge Street; CPZN-6818, Boston, MA 02114, USA.

Articles cited by this

PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92

A map of human genome variation from population-scale sequencing. Nature (2010) 121.13

Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71

A haplotype map of the human genome. Nature (2005) 105.70

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol (2010) 26.41

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol (1986) 10.84

Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis. Lancet Neurol (2010) 5.79

Intracerebral haemorrhage. Lancet (2009) 5.15

Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol (2007) 3.48

Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke (2002) 3.43

Variants at APOE influence risk of deep and lobar intracerebral hemorrhage. Ann Neurol (2010) 2.31

Validity of self-reported hypertension in the National Health and Nutrition Examination Survey III, 1988-1991. Prev Med (1997) 2.19

Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program. Diabetes (2011) 2.17

Genome-wide association studies: contribution of genomics to understanding blood pressure and essential hypertension. Curr Hypertens Rep (2010) 2.03

The effect of survival bias on case-control genetic association studies of highly lethal diseases. Circ Cardiovasc Genet (2011) 1.71

U-shaped relationship between mortality and admission blood pressure in patients with acute stroke. J Intern Med (2004) 1.67

Acute hypertensive response in patients with stroke: pathophysiology and management. Circulation (2008) 1.44

Stroke incidence and survival in the beginning of the 21st century in southern Sweden: comparisons with the late 20th century and projections into the future. Stroke (2007) 1.29

Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke (1987) 1.28

Validation of self reported diagnosis of hypertension in a cohort of university graduates in Spain. BMC Public Health (2005) 1.25

Exploiting common genetic variation to make anticoagulation safer. Stroke (2009) 1.13

A genome-wide association study of hypertension-related phenotypes in a Japanese population. Circ J (2010) 1.10

Outcome of intracerebral haemorrhage patients pre-treated with statins. Eur J Neurol (2009) 1.09

Self-reported medical history was generally accurate among Japanese workplace population. J Clin Epidemiol (2008) 1.07

Glutathione peroxidase 1 C593T polymorphism is associated with lobar intracerebral hemorrhage. Cerebrovasc Dis (2008) 0.99

Common mitochondrial sequence variants in ischemic stroke. Ann Neurol (2010) 0.97

Lack of association of lobar intracerebral hemorrhage with apolipoprotein E genotype in an unselected population. Cerebrovasc Dis (2006) 0.95

ACE variants and risk of intracerebral hemorrhage recurrence in amyloid angiopathy. Neurobiol Aging (2010) 0.91

Primary intracerebral hemorrhage: update on epidemiology, pathophysiology, and treatment strategies. Compr Ther (2009) 0.78

Articles by these authors

Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98

Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79

Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02

Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation (2009) 27.89

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2007) 22.81

Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74

Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01

Heart disease and stroke statistics--2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2006) 19.43

Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med (2010) 17.57

Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science (2010) 16.00

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2008) 15.35

Priority actions for the non-communicable disease crisis. Lancet (2011) 15.18

Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2006) 14.72

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet (2004) 12.92

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet (2008) 12.51

Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2009) 12.34

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials. Lancet (2010) 11.00

Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation (2015) 10.14

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11

Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52

Executive summary: heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation (2010) 9.18

Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet (2007) 8.68

Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke (2005) 8.05

Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature (2007) 8.03

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (2015) 7.99

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia. Nat Genet (2010) 7.08

Closure of patent foramen ovale versus medical therapy after cryptogenic stroke. N Engl J Med (2013) 7.00

Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2010) 6.93

Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol. Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology and the Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology. Eur Heart J (2005) 6.93

Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2010) 6.87

Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease. The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke (2009) 6.62

Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2014) 6.55

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31

Executive summary: heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2012) 6.24

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol (2013) 6.18

Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2013) 6.13

Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet (2015) 6.13

Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol (2009) 6.02

2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke (2015) 5.64

New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58

Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med (2004) 5.32

New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12

Inactivating mutations in NPC1L1 and protection from coronary heart disease. N Engl J Med (2014) 4.94

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87

Stroke in a biracial population: the excess burden of stroke among blacks. Stroke (2004) 4.83

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71

Early-onset stroke and vasculopathy associated with mutations in ADA2. N Engl J Med (2014) 4.70

Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol (2007) 4.68

Disparities in stroke incidence contributing to disparities in stroke mortality. Ann Neurol (2011) 4.61

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet (2004) 4.46

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38

Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol (2007) 4.11

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93

Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol (2007) 3.83

Safeguards to prevent neurologic complications after epidural steroid injections: consensus opinions from a multidisciplinary working group and national organizations. Anesthesiology (2015) 3.73

Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71

Excess stroke in Mexican Americans compared with non-Hispanic Whites: the Brain Attack Surveillance in Corpus Christi Project. Am J Epidemiol (2004) 3.69

Acute stroke care in the US: results from 4 pilot prototypes of the Paul Coverdell National Acute Stroke Registry. Stroke (2005) 3.67

The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch Intern Med (2004) 3.63

Age at stroke: temporal trends in stroke incidence in a large, biracial population. Neurology (2012) 3.62

Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. N Engl J Med (2007) 3.61

An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2013) 3.60

Polymorphisms in the non-muscle myosin heavy chain 9 gene (MYH9) are strongly associated with end-stage renal disease historically attributed to hypertension in African Americans. Kidney Int (2009) 3.58

Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study. Stroke (2010) 3.56