Acceptability in microbicide and PrEP trials: current status and a reconceptualization.

PubWeight™: 1.55‹?› | Rank: Top 4%

🔗 View Article (PMC 4026162)

Published in Curr Opin HIV AIDS on November 01, 2012

Authors

Barbara S Mensch1, Ariane van der Straten, Lauren L Katzen

Author Affiliations

1: Population Council USA, New York, NY, USA. bmensch@popcouncil.org

Articles citing this

Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med (2015) 9.20

How acceptable are antiretrovirals for the prevention of sexually transmitted HIV?: A review of research on the acceptability of oral pre-exposure prophylaxis and treatment as prevention. AIDS Behav (2014) 1.93

Microbicide clinical trial adherence: insights for introduction. J Int AIDS Soc (2013) 1.47

Oral pre-exposure prophylaxis (PrEP) for prevention of HIV in serodiscordant heterosexual couples in the United States: opportunities and challenges. AIDS Patient Care STDS (2014) 1.02

Evaluation of 3 approaches for assessing adherence to vaginal gel application in clinical trials. Sex Transm Dis (2013) 0.98

How much demand for New HIV prevention technologies can we really expect? Results from a discrete choice experiment in South Africa. PLoS One (2013) 0.92

Shape of vaginal suppositories affects willingness-to-try and preference. Antiviral Res (2012) 0.86

Reporting of Adherence in the VOICE Trial: Did Disclosure of Product Nonuse Increase at the Termination Visit? AIDS Behav (2016) 0.82

Topical microbicides and HIV prevention in the female genital tract. J Clin Pharmacol (2014) 0.81

Acceptability and use of a dapivirine vaginal ring in a phase III trial. AIDS (2017) 0.78

'People say that we are already dead much as we can still walk': a qualitative investigation of community and couples' understanding of HIV serodiscordance in rural Uganda. BMC Infect Dis (2016) 0.75

Stated product formulation preferences for HIV pre-exposure prophylaxis among women in the VOICE-D (MTN-003D) study. J Int AIDS Soc (2016) 0.75

Acceptability of an open-label wait-listed trial design: Experiences from the PROUD PrEP study. PLoS One (2017) 0.75

Implementation of a Novel Adherence Monitoring Strategy in a Phase III, Blinded, Placebo-Controlled, HIV-1 Prevention Clinical Trial. J Acquir Immune Defic Syndr (2017) 0.75

Articles cited by this

Methodological problems in AIDS behavioral research: influences on measurement error and participation bias in studies of sexual behavior. Psychol Bull (1990) 11.25

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial. Lancet (2008) 7.93

Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention. AIDS (2012) 4.26

Microbicide acceptability research: current approaches and future directions. Soc Sci Med (2005) 2.54

Acceptability of pre-exposure prophylaxis as an HIV prevention strategy: barriers and facilitators to pre-exposure prophylaxis uptake among at-risk Peruvian populations. Int J STD AIDS (2011) 2.15

Sexual risk behaviors and acceptability of HIV pre-exposure prophylaxis among HIV-negative gay and bisexual men in serodiscordant relationships: a mixed methods study. AIDS Patient Care STDS (2011) 2.13

Adherence to medications: insights arising from studies on the unreliable link between prescribed and actual drug dosing histories. Annu Rev Pharmacol Toxicol (2011) 2.09

Attitudes and acceptance of oral and parenteral HIV preexposure prophylaxis among potential user groups: a multinational study. PLoS One (2012) 2.09

Motivators, concerns, and barriers to adoption of preexposure prophylaxis for HIV prevention among gay and bisexual men in HIV-serodiscordant male relationships. AIDS Care (2011) 1.91

Safety and adherence to intermittent pre-exposure prophylaxis (PrEP) for HIV-1 in African men who have sex with men and female sex workers. PLoS One (2012) 1.84

Acceptability research on female-controlled barrier methods to prevent heterosexual transmission of HIV: Where have we been? Where are we going? J Womens Health Gend Based Med (2001) 1.84

Assessing microbicide acceptability: a comprehensive and integrated approach. AIDS Behav (2007) 1.69

Assessing the reporting of adherence and sexual activity in a simulated microbicide trial in South Africa: an interview mode experiment using a placebo gel. AIDS Behav (2011) 1.68

A framework for examining the sustained acceptability of microbicides. AIDS Behav (2005) 1.63

Sexual pleasure, gender power and microbicide acceptability in Zimbabwe and Malawi. AIDS Educ Prev (2008) 1.49

A test of the AIDS risk reduction model: psychosocial correlates of condom use in the AMEN cohort survey. Health Psychol (1994) 1.46

Willingness of Kenyan HIV-1 serodiscordant couples to use antiretroviral-based HIV-1 prevention strategies. J Acquir Immune Defic Syndr (2012) 1.44

Preexposure prophylaxis for HIV--where do we go from here? N Engl J Med (2012) 1.33

Barrier contraceptive method acceptability and choice are not reliable indicators of use. Sex Transm Dis (2003) 1.31

High acceptability of a vaginal ring intended as a microbicide delivery method for HIV prevention in African women. AIDS Behav (2012) 1.30

Acceptability of vaginal film, soft-gel capsule, and tablet as potential microbicide delivery methods among African women. J Womens Health (Larchmt) (2011) 1.22

Phase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel) in sexually active young women (MTN-004). AIDS (2011) 1.22

Willingness to accept HIV pre-exposure prophylaxis among Chinese men who have sex with men. PLoS One (2012) 1.14

Microbicide acceptability research: recent findings and evolution across phases of product development. Curr Opin HIV AIDS (2008) 1.12

"Tell Juliana": acceptability of the candidate microbicide VivaGel® and two placebo gels among ethnically diverse, sexually active young women participating in a phase 1 microbicide study. AIDS Behav (2012) 1.11

Consistent use of a combination product versus a single product in a safety trial of the diaphragm and microbicide in Harare, Zimbabwe. Contraception (2008) 1.05

Variations in microbicide gel acceptability among young women in the USA and Puerto Rico. Cult Health Sex (2011) 1.04

User experiences and acceptability attributes of the diaphragm and lubricant gel in an HIV prevention trial in southern Africa. AIDS Care (2011) 0.95

Quantitative perceptual differences among over-the-counter vaginal products using a standardized methodology: implications for microbicide development. Contraception (2011) 0.91

Acceptability of Carraguard vaginal microbicide gel among HIV-infected women in Chiang Rai, Thailand. PLoS One (2011) 0.87

Couples' acceptability of the SILCS diaphragm for microbicide delivery. Contraception (2011) 0.84

Preference between precoital and daily use of Duet® and BufferGel in Zimbabwe. AIDS Behav (2012) 0.83

The female condom: beyond acceptability to public health impact. Sex Transm Dis (2001) 0.83

Muslim women's reflections on the acceptability of vaginal microbicidal products to prevent HIV infection. Ethn Health (2011) 0.82

Acceptability and adherence: findings from a Phase II study of a candidate vaginal microbicide, 'Praneem polyherbal tablet', in Pune, India. Trans R Soc Trop Med Hyg (2010) 0.81

Indian married men's interest in microbicide use. AIDS Care (2011) 0.81

Articles by these authors

Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med (2015) 9.20

Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial. Lancet (2007) 7.22

Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study. Lancet HIV (2015) 4.33

Early age of first sex: a risk factor for HIV infection among women in Zimbabwe. AIDS (2004) 3.30

Biomarker validation of reports of recent sexual activity: results of a randomized controlled study in Zimbabwe. Am J Epidemiol (2009) 2.57

Adherence support approaches in biomedical HIV prevention trials: experiences, insights and future directions from four multisite prevention trials. AIDS Behav (2013) 2.03

Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis. PLoS Med (2011) 1.89

Adherence and its measurement in phase 2/3 microbicide trials. AIDS Behav (2010) 1.60

Type-specific cervico-vaginal human papillomavirus infection increases risk of HIV acquisition independent of other sexually transmitted infections. PLoS One (2010) 1.55

Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics of Dapivirine and Maraviroc Vaginal Rings: A Double-Blind Randomized Trial. J Acquir Immune Defic Syndr (2015) 1.32

Oral and injectable contraception use and risk of HIV acquisition among women in sub-Saharan Africa. AIDS (2013) 1.25

Consistent condom use in married Zimbabwean women after a condom intervention. Sex Transm Dis (2008) 1.13

The importance of male partner involvement for women's acceptability and adherence to female-initiated HIV prevention methods in Zimbabwe. AIDS Behav (2011) 1.10

Barrier method preferences and perceptions among Zimbabwean women and their partners. AIDS Behav (2005) 1.10

Acceptability and use of the diaphragm and Replens lubricant gel for HIV prevention in Southern Africa. AIDS Behav (2009) 1.08

The diaphragm and lubricant gel for prevention of cervical sexually transmitted infections: results of a randomized controlled trial. PLoS One (2008) 1.06

Analyzing Direct Effects in Randomized Trials with Secondary Interventions: An Application to HIV Prevention Trials. J R Stat Soc Ser A Stat Soc (2009) 1.03

Probiotics: potential to prevent HIV and sexually transmitted infections in women. Sex Transm Dis (2008) 1.03

The importance of discreet use of the diaphragm to Zimbabwean women and their partners. AIDS Behav (2006) 1.00

Degrees of disclosure: a study of women's covert use of the diaphragm in an HIV prevention trial in sub-Saharan Africa. Soc Sci Med (2009) 0.98

Introducing diaphragms into the mix: what happens to male condom use patterns? AIDS Behav (2005) 0.97

An evaluation of methods to improve the reporting of adherence in a placebo gel trial in Andhra Pradesh, India. AIDS Behav (2013) 0.97

African women recently infected with HIV-1 and HSV-2 have increased risk of acquiring Neisseria gonorrhoeae and Chlamydia trachomatis in the Methods for Improving Reproductive Health in Africa trial. Sex Transm Dis (2011) 0.97

"Male involvement" in women and children's HIV prevention: challenges in definition and interpretation. J Acquir Immune Defic Syndr (2011) 0.97

User experiences and acceptability attributes of the diaphragm and lubricant gel in an HIV prevention trial in southern Africa. AIDS Care (2011) 0.95

Male Partner Influence on Women's HIV Prevention Trial Participation and Use of Pre-exposure Prophylaxis: the Importance of "Understanding". AIDS Behav (2015) 0.95

Duet for menstrual protection: a feasibility study in Zimbabwe. Contraception (2009) 0.95

Sharing the trousers: gender roles and relationships in an HIV-prevention trial in Zimbabwe. Cult Health Sex (2012) 0.94

Feasibility of a breath test for monitoring adherence to vaginal administration of antiretroviral microbicide gels. J Clin Pharmacol (2013) 0.93

Contraception use and effectiveness among women in a trial of the diaphragm for HIV prevention. Contraception (2011) 0.92

An acceptability and safety study of the Duet cervical barrier and gel delivery system in Zimbabwe. J Int AIDS Soc (2010) 0.92

A comparison of four condom-use measures in predicting pregnancy, cervical STI and HIV incidence among Zimbabwean women. Sex Transm Infect (2009) 0.90

"Come back when you're dying:" the commodification of AIDS among California's urban poor. Soc Sci Med (2002) 0.89

Female condom uptake and acceptability in Zimbabwe. AIDS Educ Prev (2008) 0.88

Influences on visit retention in clinical trials: insights from qualitative research during the VOICE trial in Johannesburg, South Africa. BMC Womens Health (2014) 0.87

Intimate partner violence and condom and diaphragm nonadherence among women in an HIV prevention trial in southern Africa. J Acquir Immune Defic Syndr (2013) 0.86

Diaphragm and lubricant gel acceptance, skills and patterns of use among women in an effectiveness trial in Southern Africa. Eur J Contracept Reprod Health Care (2009) 0.85

Sexually transmitted infections and reproductive health morbidity in a cohort of female sex workers screened for a microbicide feasibility study in Nellore, India. Glob J Health Sci (2013) 0.85

The effect of the vaginal diaphragm and lubricant gel on acquisition of HSV-2. Sex Transm Infect (2011) 0.83

Use of the dye stain assay and ultraviolet light test for assessing vaginal insertion of placebo-filled applicators before and after sex. Sex Transm Dis (2013) 0.83

Using a 2-stage strategy with respondent-driven sampling to recruit a hard-to-reach population for a placebo microbicide gel clinical trial in Nellore, Andhra Pradesh (India). AIDS Behav (2015) 0.82

First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence, and Pharmacodynamics. J Acquir Immune Defic Syndr (2016) 0.82

What the better half is thinking: A comparison of men's and women's responses and agreement between spouses regarding reported sexual and reproductive behaviors in Rwanda. Psychol Res Behav Manag (2009) 0.81

Characteristics of female sex workers in southern India willing and unwilling to participate in a placebo gel trial. AIDS Behav (2013) 0.80

Impact of learning HIV status on contraceptive use in the MIRA trial. J Fam Plann Reprod Health Care (2011) 0.80

A qualitative study of obstacles to diaphragm and condom use in an HIV prevention trial in sub-Saharan Africa. AIDS Educ Prev (2012) 0.79

Establishing a continuum of care between HIV prevention trials and public healthcare systems: the MIRA Standard of Care program. Clin Trials (2010) 0.78

Changes in sexual risk behavior before and after HIV seroconversion in Southern African women enrolled in a HIV prevention trial. J Acquir Immune Defic Syndr (2011) 0.78

Acceptability and use of a dapivirine vaginal ring in a phase III trial. AIDS (2017) 0.78

Diaphragm used with replens gel and risk of bacterial vaginosis: results from a randomized controlled trial. Infect Dis Obstet Gynecol (2012) 0.76

Bridewealth and sexual and reproductive practices among women in Harare, Zimbabwe. AIDS Care (2010) 0.75

"It's inside my body and it's mine". AIDS (2017) 0.75

To tell or not to tell: male partner engagement in a Phase 3 microbicide efficacy trial in South Africa. Cult Health Sex (2015) 0.75