PubRank

John C Whittaker

Author PubWeight™ 95.68‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science 2012 7.94
2 Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS Genet 2008 6.66
3 The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet 2012 4.87
4 Sequence-level population simulations over large genomic regions. Genetics 2007 4.04
5 Genome-wide significance for dense SNP and resequencing data. Genet Epidemiol 2008 3.26
6 A Bayesian toolkit for genetic association studies. Genet Epidemiol 2006 2.86
7 Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med 2013 2.73
8 Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nat Genet 2007 2.38
9 Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet 2011 2.35
10 Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol 2012 2.34
11 Fregene: simulation of realistic sequence-level data in populations and ascertained samples. BMC Bioinformatics 2008 2.23
12 Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia. Am J Psychiatry 2009 2.21
13 Genome-wide association study of major recurrent depression in the U.K. population. Am J Psychiatry 2010 2.17
14 Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials. Am J Epidemiol 2006 2.16
15 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet 2012 1.96
16 Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study. Lancet Neurol 2009 1.94
17 Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J 2011 1.73
18 Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. PLoS One 2011 1.72
19 Bayesian graphical models for genomewide association studies. Am J Hum Genet 2006 1.66
20 HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer. J Clin Oncol 2011 1.60
21 Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. J Clin Oncol 2011 1.56
22 Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet 2008 1.44
23 Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity. Proc Natl Acad Sci U S A 2003 1.33
24 Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate. BJOG 2004 1.30
25 The clonal evolution of metastases from primary serous epithelial ovarian cancers. Int J Cancer 2009 1.29
26 Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS One 2012 1.28
27 Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals. Atherosclerosis 2010 1.27
28 Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions. Genet Epidemiol 2005 1.16
29 A multi-SNP locus-association method reveals a substantial fraction of the missing heritability. Am J Hum Genet 2012 1.07
30 Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PLoS One 2013 1.02
31 Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol 2013 1.02
32 Multilocus Bayesian meta-analysis of gene-disease associations. Am J Hum Genet 2009 1.00
33 Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation. Diabetes 2012 1.00
34 Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors. Mass Spectrom Rev 2008 1.00
35 Racial variation in the association between gestational age and perinatal mortality: prospective study. BMJ 2007 0.99
36 Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight. Am J Hum Genet 2012 0.98
37 Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus. Eur J Hum Genet 2010 0.98
38 Maternal and fetal characteristics associated with meconium-stained amniotic fluid. Obstet Gynecol 2011 0.92
39 The benefits of using genetic information to design prevention trials. Am J Hum Genet 2013 0.91
40 The structure of interrupted human AC microsatellites. Mol Biol Evol 2003 0.90
41 Using statistical models to identify factors that have a role in defining the abundance of ions produced by tandem MS. Anal Chem 2007 0.86
42 Comparison of methods and sampling designs to test for association between rare variants and quantitative traits. Genet Epidemiol 2011 0.86
43 Comparison of statistical tests for association between rare variants and binary traits. PLoS One 2012 0.86
44 Timing of planned cesarean delivery by racial group. Obstet Gynecol 2008 0.85
45 Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus. Arthritis Rheum 2008 0.85
46 Family-based association analysis with ordered categorical phenotypes, covariates and interactions. Genet Epidemiol 2007 0.85
47 An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism. Invest Ophthalmol Vis Sci 2009 0.85
48 A comparison of Bayesian and frequentist approaches to incorporating external information for the prediction of prostate cancer risk. Genet Epidemiol 2012 0.84
49 Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe. Hum Mutat 2012 0.83
50 Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study. BMC Genet 2003 0.83
51 Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design. Am J Ophthalmol 2012 0.82
52 Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clin Cancer Res 2008 0.82
53 Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach. Hum Genet 2008 0.80
54 Bayesian semiparametric meta-analysis for genetic association studies. Genet Epidemiol 2011 0.79
55 Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease. Am J Hum Genet 2009 0.78
56 High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort. J Nutr 2011 0.78
57 On the structural differences between markers and genomic AC microsatellites. J Mol Evol 2005 0.78
58 The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study. BMJ Open 2013 0.77
59 Statistical design and analysis of pharmacogenetic trials. Stat Med 2005 0.76
60 A Bayesian approach to disease gene location using allelic association. Biostatistics 2003 0.75