Published in Arthritis Res Ther on October 18, 2012
Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis'. Arthritis Res Ther (2013) 0.79
Preventing Heart Failure in Inflammatory and Immune Disorders. Curr Cardiovasc Risk Rep (2014) 0.78
Cardiac Mitochondrial Respiratory Dysfunction and Tissue Damage in Chronic Hyperglycemia Correlate with Reduced Aldehyde Dehydrogenase-2 Activity. PLoS One (2016) 0.75
Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply. Arthritis Res Ther (2013) 0.75
An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis. Inflamm Res (2017) 0.75
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med (1991) 16.01
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation (2003) 6.62
Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res (2005) 4.79
Cardiovascular death in rheumatoid arthritis: a population-based study. Arthritis Rheum (2005) 4.63
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science (2008) 4.32
Cardiac fibroblasts: at the heart of myocardial remodeling. Pharmacol Ther (2009) 4.21
Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr (2006) 3.09
Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol (1995) 3.00
Aldosterone induces a vascular inflammatory phenotype in the rat heart. Am J Physiol Heart Circ Physiol (2002) 2.94
Free radicals and antioxidants in the year 2000. A historical look to the future. Ann N Y Acad Sci (2000) 2.47
Independent association of rheumatoid arthritis with increased left ventricular mass but not with reduced ejection fraction. Arthritis Rheum (2009) 2.33
Role of reactive aldehyde in cardiovascular diseases. Free Radic Biol Med (2000) 2.20
Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study. J Am Coll Cardiol (2004) 2.17
4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med Res Rev (2008) 2.02
Role of the renin-angiotensin system in vascular inflammation. Trends Pharmacol Sci (2008) 1.97
Oxidation in rheumatoid arthritis. Arthritis Res Ther (2004) 1.96
C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease. Hypertension (2010) 1.85
Angiotensin-converting enzyme inhibition improves vascular function in rheumatoid arthritis. Circulation (2008) 1.85
Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling. Acta Biochim Pol (2003) 1.67
Oxidized phospholipids as modulators of inflammation in atherosclerosis. Curr Opin Lipidol (2003) 1.65
Role of 4-hydroxynonenal in stress-mediated apoptosis signaling. Mol Aspects Med (2003) 1.57
Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the angiotensin II type 1 receptor. Circ Res (2003) 1.53
4-hydroxynonenal as a bioactive marker of pathophysiological processes. Mol Aspects Med (2003) 1.49
4-Hydroxynonenal in the pathomechanisms of oxidative stress. IUBMB Life (2001) 1.47
Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart. Free Radic Biol Med (2005) 1.35
The pathogenesis of rheumatoid arthritis: pivotal cytokines involved in bone degradation and inflammation. J Rheumatol Suppl (2002) 1.34
Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury. J Biol Chem (2003) 1.32
Combination benefit of treatment with the cytokine inhibitors interleukin-1 receptor antagonist and PEGylated soluble tumor necrosis factor receptor type I in animal models of rheumatoid arthritis. Arthritis Rheum (2000) 1.31
Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis. Circ J (2009) 1.25
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function. Circ Res (2003) 1.25
Cardiac mitochondrial NADP+-isocitrate dehydrogenase is inactivated through 4-hydroxynonenal adduct formation: an event that precedes hypertrophy development. J Biol Chem (2003) 1.23
ANG II-induced cardiac molecular and cellular events: role of aldosterone. Am J Physiol Heart Circ Physiol (2006) 1.23
4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells. J Hepatol (2004) 1.14
Adiponectin mediates cardioprotection in oxidative stress-induced cardiac myocyte remodeling. Am J Physiol Heart Circ Physiol (2011) 1.14
Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis. Arthritis Res Ther (2005) 1.13
The development of myocardial fibrosis in transgenic mice with targeted overexpression of tumor necrosis factor requires mast cell-fibroblast interactions. Circulation (2011) 1.12
Declines in mitochondrial respiration during cardiac reperfusion: age-dependent inactivation of alpha-ketoglutarate dehydrogenase. Proc Natl Acad Sci U S A (1999) 1.11
Role of AT2 receptors in the cardioprotective effect of AT1 antagonists in mice. Hypertension (2002) 1.10
Angiotensin II and oxidative stress in Dahl Salt-sensitive rat with heart failure. Hypertension (2002) 1.09
The non-thiol angiotensin-converting enzyme inhibitor quinapril suppresses inflammatory arthritis. Rheumatology (Oxford) (2004) 1.06
Receptor-mediated effects of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension (1992) 1.03
Interaction between oxidative stress and high-density lipoprotein cholesterol is associated with severity of coronary artery calcification in rheumatoid arthritis. Arthritis Care Res (Hoboken) (2010) 1.02
Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury. Pflugers Arch (2010) 0.99
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers. Arthritis Rheum (2010) 0.99
Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradation. Arthritis Rheum (2006) 0.98
Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis. J Cell Biochem (2011) 0.96
Bone-protective effects of nonviral gene therapy with folate-chitosan DNA nanoparticle containing interleukin-1 receptor antagonist gene in rats with adjuvant-induced arthritis. Mol Ther (2008) 0.94
Differential effects of kinins on cardiomyocyte hypertrophy and interstitial collagen matrix in the surviving myocardium after myocardial infarction in the rat. Circulation (1997) 0.93
Cartilage destruction and bone erosion in arthritis: the role of tumour necrosis factor alpha. Ann Rheum Dis (2000) 0.93
The role of phospholipid oxidation products in inflammatory and autoimmune diseases: evidence from animal models and in humans. Subcell Biochem (2008) 0.92
Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase. Arthritis Rheum (2006) 0.92
Effects of Angiotensin-converting enzyme inhibition and statin treatment on inflammatory markers and endothelial functions in patients with longterm rheumatoid arthritis. J Rheumatol (2005) 0.91
High redox thioredoxin but low thioredoxin reductase activities in the serum of patients with rheumatoid arthritis. Clin Chim Acta (2006) 0.91
Energetic myocardial metabolism and oxidative stress: let's make them our friends in the fight against heart failure. Biomed Pharmacother (2009) 0.90
A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis. Arthritis Rheum (2011) 0.88
Prevalence of anti-3-nitrotyrosine antibodies in the joint synovial fluid of patients with rheumatoid arthritis, osteoarthritis and systemic lupus erythematosus. Clin Chim Acta (2006) 0.87
The interrelation of glutathione reductase, catalase, glutathione peroxidase, superoxide dismutase, and glucose-6-phosphate in the pathogenesis of rheumatoid arthritis. Clin Rheumatol (2007) 0.85
The cardiac renin-angiotensin system is responsible for high-salt diet-induced left ventricular hypertrophy in mice. Eur J Heart Fail (2010) 0.85
Inhibition of the mitochondrial permeability transition by aldehydes. Biochem Biophys Res Commun (2002) 0.82
Role of 4-hydroxy-2,3-nonenal in the pathogenesis of fibrosis. Biofactors (2005) 0.81
Angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and the risk of developing rheumatoid arthritis in antihypertensive drug users. Pharmacoepidemiol Drug Saf (2012) 0.80
Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes. Arthritis Res Ther (2010) 0.79
Oxidative status of DBA/1J mice with type II collagen-induced arthritis. J Appl Toxicol (2007) 0.78
Protective effect of NADP-isocitrate dehydrogenase on the paraquat-mediated oxidative inactivation of aconitase in heart mitochondria. Environ Toxicol Pharmacol (2006) 0.77
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol (2010) 5.14
A newly characterized SCN5A mutation underlying Brugada syndrome unmasked by hyperthermia. J Cardiovasc Electrophysiol (2003) 2.24
Cyclooxygenase-2 and prostaglandins in articular tissues. Semin Arthritis Rheum (2003) 2.22
The long-term incidence of subsequent vertebral body fracture after vertebral augmentation therapy: a systemic review and meta-analysis. Pain Physician (2012) 1.43
Characterization of folate-chitosan-DNA nanoparticles for gene therapy. Biomaterials (2005) 1.42
Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia. Am J Physiol Heart Circ Physiol (2002) 1.41
Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles. Biomaterials (2003) 1.35
Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. Eur J Pharm Biopharm (2004) 1.33
In vivo selective inhibition of mitogen-activated protein kinase kinase 1/2 in rabbit experimental osteoarthritis is associated with a reduction in the development of structural changes. Arthritis Rheum (2003) 1.24
Novel molecular mechanism involving alpha1D (Cav1.3) L-type calcium channel in autoimmune-associated sinus bradycardia. Circulation (2005) 1.23
Role of TL1A in the pathogenesis of rheumatoid arthritis. J Immunol (2009) 1.18
Localization and modulation of {alpha}1D (Cav1.3) L-type Ca channel by protein kinase A. Am J Physiol Heart Circ Physiol (2004) 1.11
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1. J Biol Chem (2004) 1.09
PPARgamma ligands as modulators of inflammatory and catabolic responses in arthritis. An overview. J Rheumatol (2002) 1.08
Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes. Arthritis Res Ther (2007) 1.06
Validation of an advanced practice physiotherapy model of care in an orthopaedic outpatient clinic. BMC Musculoskelet Disord (2013) 1.03
Expression and regulation of microsomal prostaglandin E synthase-1 in human osteoarthritic cartilage and chondrocytes. J Rheumatol (2005) 1.02
New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets. Curr Rheumatol Rep (2006) 1.02
Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors. Bone (2008) 1.02
Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury. Pflugers Arch (2010) 0.99
Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradation. Arthritis Rheum (2006) 0.98
Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes. J Cell Biochem (2012) 0.98
Polycation-based gene therapy: current knowledge and new perspectives. Curr Gene Ther (2011) 0.97
Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study. Arthritis Res Ther (2007) 0.97
Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis. J Cell Biochem (2011) 0.96
Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes. Arthritis Rheum (2011) 0.96
4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase. Arthritis Res Ther (2008) 0.95
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. Arthritis Rheum (2008) 0.95
Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium. Ann Rheum Dis (2012) 0.95
Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade. J Cell Biochem (2007) 0.94
Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids. Arthritis Rheum (2004) 0.94
Bone-protective effects of nonviral gene therapy with folate-chitosan DNA nanoparticle containing interleukin-1 receptor antagonist gene in rats with adjuvant-induced arthritis. Mol Ther (2008) 0.94
Uptake mechanisms of non-viral gene delivery. J Control Release (2011) 0.93
Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro. Acta Biochim Biophys Sin (Shanghai) (2004) 0.93
Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal. Arthritis Res Ther (2006) 0.92
Progress and prospects of chitosan and its derivatives as non-viral gene vectors in gene therapy. Curr Gene Ther (2009) 0.90
Atorvastatin prevents early apoptosis after thoracic spinal cord contusion injury and promotes locomotion recovery. Neurosci Lett (2009) 0.90
Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype. Am J Pathol (2013) 0.89
Synthetic and natural polycations for gene therapy: state of the art and new perspectives. Curr Gene Ther (2006) 0.89
Involvement of miR-143 in cisplatin resistance of gastric cancer cells via targeting IGF1R and BCL2. Tumour Biol (2014) 0.89
Association of cartilage-specific deletion of peroxisome proliferator-activated receptor γ with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum (2012) 0.88
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis. Arthritis Res Ther (2011) 0.87
Adoptive transfer of CD4+CD25+ regulatory T cells for prevention and treatment of spontaneous abortion. Eur J Obstet Gynecol Reprod Biol (2012) 0.87
Single intravenous low-dose injections of connexin 43 mimetic peptides protect ischemic heart in vivo against myocardial infarction. J Mol Cell Cardiol (2012) 0.86
Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation. Pharmacogn Mag (2012) 0.86
Low molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization studies. Int J Nanomedicine (2012) 0.86
Inhibition of interleukin-1beta-induced cyclooxygenase 2 expression in human synovial fibroblasts by 15-deoxy-Delta12,14-prostaglandin J2 through a histone deacetylase-independent mechanism. Arthritis Rheum (2005) 0.86
CD40 is a regulator for vascular endothelial growth factor in the tumor microenvironment of glioma. J Neuroimmunol (2010) 0.86
Efficacy of intra-articular injection of celecoxib in a rabbit model of osteoarthritis. Int J Mol Sci (2010) 0.86
Acute effect of Ghrelin on ischemia/reperfusion injury in the rat spinal cord. Int J Mol Sci (2012) 0.85
Different roles of PD-L1 and FasL in immunomodulation mediated by human placenta-derived mesenchymal stem cells. Hum Immunol (2012) 0.85
ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma. J Mol Histol (2013) 0.85
Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression. Behav Brain Res (2011) 0.85
Clinicopathologic correlation of cancer stem cell markers CD44, CD24, VEGF and HIF-1α in ductal carcinoma in situ and invasive ductal carcinoma of breast: an immunohistochemistry-based pilot study. Pathol Res Pract (2011) 0.85
The immunologic properties of undifferentiated and osteogenic differentiated mouse mesenchymal stem cells and its potential application in bone regeneration. Immunobiology (2008) 0.85
Sensitization of osteosarcoma cell line SaOS-2 to chemotherapy by downregulating survivin. Arch Med Res (2010) 0.85
Positive Epstein-Barr virus and cytomegalovirus IgM assays in primary HIV infection. J Med Virol (2011) 0.85
Apoptosis of multiple myeloma cells induced by agonist monoclonal antibody against human CD28. Cell Immunol (2005) 0.84
HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity. J Cell Biochem (2009) 0.84
In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis. Arthritis Rheum (2012) 0.84
Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes. Arthritis Res Ther (2014) 0.83
Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production. Arthritis Res Ther (2005) 0.83
Time courses of B7 family molecules expressed on activated T-cells and their biological significance. Cell Immunol (2005) 0.83
Metabolic activity of osteoblasts retrieved from osteoarthritic patients after stimulation with mediators involved in periprosthetic loosening. Bone (2004) 0.83
NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis. Arthritis Res Ther (2013) 0.83
Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro. Int J Nanomedicine (2013) 0.83
The role of TLR and chemokine in wear particle-induced aseptic loosening. J Biomed Biotechnol (2012) 0.82
Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes. Inflamm Res (2014) 0.82