Charles G Drake

Author PubWeight™ 211.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012 52.99
2 Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N Engl J Med 2012 35.24
3 Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010 17.13
4 Inflammation in prostate carcinogenesis. Nat Rev Cancer 2007 9.08
5 Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol 2012 7.26
6 Role of LAG-3 in regulatory T cells. Immunity 2004 4.36
7 Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol 2007 4.29
8 Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape. Cancer Res 2011 3.81
9 Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody. Clin Cancer Res 2012 3.68
10 Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clin Cancer Res 2008 3.09
11 Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood 2007 2.93
12 Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res 2013 2.81
13 Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science 2009 2.76
14 A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells. Blood 2007 2.69
15 Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines. Blood 2005 2.60
16 LAG-3 regulates CD8+ T cell accumulation and effector function in murine self- and tumor-tolerance systems. J Clin Invest 2007 2.57
17 Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study. Lancet Oncol 2012 2.31
18 Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int J Radiat Oncol Biol Phys 2013 2.28
19 Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. Prostate 2009 2.17
20 Ipilimumab: an anti-CTLA-4 antibody for metastatic melanoma. Clin Cancer Res 2011 1.97
21 B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells. J Immunol 2005 1.78
22 A role for the transcription factor Helios in human CD4(+)CD25(+) regulatory T cells. Mol Immunol 2010 1.65
23 Bacteriolytic therapy can generate a potent immune response against experimental tumors. Proc Natl Acad Sci U S A 2004 1.63
24 The composition and signaling of the IL-35 receptor are unconventional. Nat Immunol 2012 1.63
25 Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer Epidemiol Biomarkers Prev 2014 1.61
26 Androgen receptor as a licensing factor for DNA replication in androgen-sensitive prostate cancer cells. Proc Natl Acad Sci U S A 2006 1.61
27 Functionally distinct LAG-3 and PD-1 subsets on activated and chronically stimulated CD8 T cells. J Immunol 2009 1.60
28 LAG-3 in Cancer Immunotherapy. Curr Top Microbiol Immunol 2011 1.58
29 Tc17 CD8 T cells: functional plasticity and subset diversity. J Immunol 2009 1.54
30 Phenotypic and functional properties of Helios+ regulatory T cells. PLoS One 2012 1.52
31 Cyclophosphamide augments antitumor immunity: studies in an autochthonous prostate cancer model. Cancer Res 2009 1.51
32 Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. Prostate 2009 1.45
33 A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression. J Pathol 2015 1.45
34 Parabolic resection for mitral valve repair. Interact Cardiovasc Thorac Surg 2009 1.39
35 Molecular pathways: coexpression of immune checkpoint molecules: signaling pathways and implications for cancer immunotherapy. Clin Cancer Res 2013 1.39
36 Immunotherapy for prostate cancer: recent advances, lessons learned, and areas for further research. Clin Cancer Res 2011 1.38
37 LAG-3 regulates plasmacytoid dendritic cell homeostasis. J Immunol 2009 1.33
38 Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3. J Immunol 2011 1.28
39 Glycoprotein 96 can chaperone both MHC class I- and class II-restricted epitopes for in vivo presentation, but selectively primes CD8+ T cell effector function. J Immunol 2004 1.21
40 CD4+ T cells pass through an effector phase during the process of in vivo tolerance induction. J Immunol 2003 1.19
41 Radiotherapy augments the immune response to prostate cancer in a time-dependent manner. Prostate 2008 1.17
42 Prostate cancer immunotherapy. Clin Cancer Res 2011 1.11
43 Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4. Eur J Immunol 2010 1.09
44 Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells. J Immunol 2009 1.07
45 Current status of immunological therapies for prostate cancer. Curr Opin Urol 2010 1.06
46 STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model. J Immunol 2009 1.06
47 Allogeneic versus autologous blood transfusion and survival after radical prostatectomy. Transfusion 2014 1.00
48 Intra-individual variation in serum C-reactive protein over 4 years: an implication for epidemiologic studies. Cancer Causes Control 2010 0.99
49 Cutting Edge: TCR-induced NAB2 enhances T cell function by coactivating IL-2 transcription. J Immunol 2006 0.98
50 Immunotherapy for prostate cancer: walk, don't run. J Clin Oncol 2009 0.96
51 Variation in IL10 and other genes involved in the immune response and in oxidation and prostate cancer recurrence. Cancer Epidemiol Biomarkers Prev 2012 0.94
52 Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data. PLoS Med 2009 0.94
53 Sequencing CTLA-4 blockade with cell-based immunotherapy for prostate cancer. J Transl Med 2013 0.93
54 Combining immunological and androgen-directed approaches: an emerging concept in prostate cancer immunotherapy. Curr Opin Oncol 2012 0.92
55 Immunotherapy for prostate cancer: recent developments and future challenges. Cancer Metastasis Rev 2014 0.90
56 Immune modulation and stereotactic radiation: improving local and abscopal responses. Biomed Res Int 2013 0.90
57 Complete biochemical (prostate-specific antigen) response to sipuleucel-T with enzalutamide in castration-resistant prostate cancer: a case report with implications for future research. Urology 2013 0.89
58 Immune signatures predict prognosis in localized cancer. Cancer Invest 2010 0.88
59 Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatment. Oncology (Williston Park) 2015 0.85
60 Re: interdisciplinary critique of sipuleucel-T as immunotherapy in castration-resistant prostate cancer. J Natl Cancer Inst 2012 0.83
61 Epithelial architectural destruction is necessary for bone marrow derived cell contribution to regenerating prostate epithelium. J Urol 2006 0.82
62 Cyclophosphamide unmasks an antimetastatic effect of local tumor cryoablation. J Pharmacol Exp Ther 2009 0.82
63 Lenalidomide modulates IL-8 and anti-prostate antibody levels in men with biochemically recurrent prostate cancer. Prostate 2011 0.81
64 Combined treatment effects of radiation and immunotherapy: studies in an autochthonous prostate cancer model. Int J Radiat Oncol Biol Phys 2013 0.81
65 Anti-tumor effects of endogenous prostate cancer-specific CD8 T cells in a murine TCR transgenic model. Prostate 2011 0.81
66 Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells. Immunol Cell Biol 2011 0.80
67 Combinatorial Immunotherapy: PD-1 may not be LAG-ing behind any more. Oncoimmunology 2012 0.78
68 Visceral metastases and prostate cancer treatment: 'die hard,' 'tough neighborhoods,' or 'evil humors'? Oncology (Williston Park) 2014 0.78
69 Eleventh Prouts Neck Meeting on Prostate Cancer: emerging strategies in prostate cancer therapy. Cancer Res 2007 0.77
70 Strain-specific induction of experimental autoimmune prostatitis (EAP) in mice. Prostate 2012 0.77
71 Harnessing the PD-1 pathway in renal cell carcinoma: current evidence and future directions. BioDrugs 2014 0.76
72 Personalized Immune Therapy: A Slippery Fish? Oncology (Williston Park) 2016 0.75
73 Current immunotherapeutic strategies in prostate cancer. Surg Oncol Clin N Am 2007 0.75
74 Cutaneous Eruptions in Patients Receiving Immune Checkpoint Blockade: Clinicopathologic Analysis of the Nonlichenoid Histologic Pattern. Am J Surg Pathol 2017 0.75
75 Combination immunotherapy in renal cell carcinoma. Clin Adv Hematol Oncol 2016 0.75