Published in EMBO J on December 04, 2012
Dna2 is involved in CA strand resection and nascent lagging strand completion at native yeast telomeres. J Biol Chem (2013) 0.77
Molecular mechanisms involved in initiation of the DNA damage response. Mol Cell Oncol (2015) 0.76
Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol (1991) 33.90
Checkpoints: controls that ensure the order of cell cycle events. Science (1989) 21.01
Human CtIP promotes DNA end resection. Nature (2007) 10.63
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev (1994) 8.53
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature (2008) 8.15
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell (2008) 7.63
Double-strand break end resection and repair pathway choice. Annu Rev Genet (2011) 7.31
Recombination proteins in yeast. Annu Rev Genet (2004) 7.04
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol Cell (2007) 5.31
rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint. Science (1996) 5.13
Removal of nonhomologous DNA ends in double-strand break recombination: the role of the yeast ultraviolet repair gene RAD1. Science (1992) 5.08
DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev (2008) 5.07
A site-specific endonuclease essential for mating-type switching in Saccharomyces cerevisiae. Cell (1983) 5.05
DNA repair mutants defining G2 checkpoint pathways in Schizosaccharomyces pombe. EMBO J (1992) 4.98
Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast. Mol Biol Cell (1994) 4.58
Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1). EMBO J (1997) 3.96
Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre. Nat Cell Biol (2003) 3.86
Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene (1992) 3.86
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A (1997) 3.66
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc Natl Acad Sci U S A (1995) 3.59
The structural determinants of checkpoint activation. Genes Dev (2007) 3.53
DNA end resection: many nucleases make light work. DNA Repair (Amst) (2009) 3.28
RAD1 and RAD10, but not other excision repair genes, are required for double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.90
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc Natl Acad Sci U S A (2003) 2.80
The G2-phase DNA-damage checkpoint. Trends Cell Biol (2000) 2.64
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J Biol Chem (2001) 2.60
The rad18 gene of Schizosaccharomyces pombe defines a new subgroup of the SMC superfamily involved in DNA repair. Mol Cell Biol (1995) 2.52
The product of the HO gene is a nuclease: purification and characterization of the enzyme. Cold Spring Harb Symp Quant Biol (1984) 2.36
Competition between the Rad50 complex and the Ku heterodimer reveals a role for Exo1 in processing double-strand breaks but not telomeres. Mol Cell Biol (2003) 2.33
Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex. Nat Cell Biol (2001) 2.29
Break dosage, cell cycle stage and DNA replication influence DNA double strand break response. EMBO J (2008) 2.21
Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage. Mol Cell Biol (1994) 2.13
DNA mismatch repair and mutation avoidance pathways. J Cell Physiol (2002) 1.96
Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2. EMBO J (2010) 1.92
The RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activities. J Biol Chem (1999) 1.91
Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. Mol Cell Biol (2004) 1.83
Cloning and characterisation of the Schizosaccharomyces pombe rad32 gene: a gene required for repair of double strand breaks and recombination. Nucleic Acids Res (1995) 1.82
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest. J Cell Sci (2002) 1.75
Rfc4 interacts with Rpa1 and is required for both DNA replication and DNA damage checkpoints in Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.58
Characterization of the alternative excision repair pathway of UV-damaged DNA in Schizosaccharomyces pombe. Nucleic Acids Res (1997) 1.58
Smc5/6 is required for repair at collapsed replication forks. Mol Cell Biol (2006) 1.51
The fission yeast Cdc1 protein, a homologue of the small subunit of DNA polymerase delta, binds to Pol3 and Cdc27. EMBO J (1996) 1.49
Coordination of DNA damage responses via the Smc5/Smc6 complex. Mol Cell Biol (2004) 1.49
Identification of the Xenopus DNA2 protein as a major nuclease for the 5'->3' strand-specific processing of DNA ends. Nucleic Acids Res (2008) 1.47
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1. EMBO J (2004) 1.38
DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51. Nucleic Acids Res (2004) 1.38
Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function. Mol Gen Genet (1997) 1.33
G2 damage checkpoints: what is the turn-on? J Cell Sci (2005) 1.29
Brc1-mediated DNA repair and damage tolerance. Genetics (2005) 1.18
Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity. Nucleic Acids Res (2007) 1.18
Relationships between yeast Rad27 and Apn1 in response to apurinic/apyrimidinic (AP) sites in DNA. Nucleic Acids Res (1999) 1.16
The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity. J Biol Chem (2004) 1.16
Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast. Mol Gen Genet (1998) 1.15
Shedding light on the DNA damage checkpoint. Cell Cycle (2007) 1.14
The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer? Cancer Biol Ther (2009) 1.14
Regulation of chk1. Cell Div (2009) 1.12
DNA damage checkpoint maintenance through sustained Chk1 activity. J Cell Sci (2004) 1.05
Double-strand break-induced mitotic intrachromosomal recombination in the fission yeast Schizosaccharomyces pombe. Genetics (1996) 1.05
Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes. Mol Cell Biol (2009) 1.04
Regulation of Chk1 by its C-terminal domain. Mol Biol Cell (2008) 1.03
Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst) (2010) 1.03
Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks. Mol Cell Biol (2010) 0.98
Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. Genetics (2007) 0.97
Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe. Nucleic Acids Res (2005) 0.96
Molecular cloning and sequence analysis of cdc27+ required for the G2-M transition in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1992) 0.90
Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1. Genetics (2010) 0.89
Antagonism of Chk1 signaling in the G2 DNA damage checkpoint by dominant alleles of Cdr1. Genetics (2006) 0.87
Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes. Mol Biol Cell (2011) 0.81
The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpoint. Genetics (2010) 0.79
The molecular organization of the Star/asteroid region, a region necessary for proper eye development in Drosophila melanogaster. Genome (1993) 0.78
A new method to efficiently induce a site-specific double-strand break in the fission yeast Schizosaccharomyces pombe. Yeast (2012) 0.77
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest. J Cell Sci (2002) 1.75
Smc5/6 is required for repair at collapsed replication forks. Mol Cell Biol (2006) 1.51
Coordination of DNA damage responses via the Smc5/Smc6 complex. Mol Cell Biol (2004) 1.49
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1. EMBO J (2004) 1.38
Fission yeast Rnf4 homologs are required for DNA repair. J Biol Chem (2007) 1.37
Smc5/6 maintains stalled replication forks in a recombination-competent conformation. EMBO J (2009) 1.23
Brc1-mediated DNA repair and damage tolerance. Genetics (2005) 1.18
Regulation of checkpoint kinases through dynamic interaction with Crb2. EMBO J (2004) 1.15
The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer? Cancer Biol Ther (2009) 1.14
Regulation of chk1. Cell Div (2009) 1.12
DNA damage checkpoint maintenance through sustained Chk1 activity. J Cell Sci (2004) 1.05
Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes. Mol Cell Biol (2009) 1.04
Regulation of Chk1 by its C-terminal domain. Mol Biol Cell (2008) 1.03
The fission yeast NIMA kinase Fin1p is required for spindle function and nuclear envelope integrity. EMBO J (2002) 1.00
Normal p53 function in primary cells deficient for Siah genes. Mol Cell Biol (2002) 0.99
Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. Genetics (2007) 0.97
Structural maintenance of chromosomes (SMC) proteins, a family of conserved ATPases. Genome Biol (2002) 0.96
Regulation of TIP60 by ATF2 modulates ATM activation. J Biol Chem (2008) 0.96
Resisting arrest: recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1. Cell Cycle (2004) 0.96
Histone H3 lysine 14 acetylation is required for activation of a DNA damage checkpoint in fission yeast. J Biol Chem (2011) 0.93
Skp2B stimulates mammary gland development by inhibiting REA, the repressor of the estrogen receptor. Mol Cell Biol (2007) 0.92
Cell-cycle responses to DNA damage in G2. Int Rev Cytol (2003) 0.91
Turning off the G2 DNA damage checkpoint. DNA Repair (Amst) (2007) 0.91
Cyclin D1 overexpression and response to bortezomib treatment in a breast cancer model. J Natl Cancer Inst (2006) 0.90
Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1. Genetics (2010) 0.89
SMC complexes and topoisomerase II work together so that sister chromatids can work apart. Cell Cycle (2010) 0.88
Brc1-dependent recovery from replication stress. J Cell Sci (2012) 0.88
Antagonism of Chk1 signaling in the G2 DNA damage checkpoint by dominant alleles of Cdr1. Genetics (2006) 0.87
A new SUMO ligase in the DNA damage response. DNA Repair (Amst) (2005) 0.86
Regulatory motifs in Chk1. Cell Cycle (2013) 0.81
Nse1-dependent recruitment of Smc5/6 to lesion-containing loci contributes to the repair defects of mutant complexes. Mol Biol Cell (2011) 0.81
Functional interplay between cohesin and Smc5/6 complexes. Chromosoma (2014) 0.81
H2A.Z-dependent regulation of cohesin dynamics on chromosome arms. Mol Cell Biol (2014) 0.79
Cyclin d1 overexpression sensitizes breast cancer cells to fenretinide. Clin Cancer Res (2003) 0.79
Cell cycle regulation by checkpoints. Methods Mol Biol (2014) 0.77
Methods for studying checkpoint kinases - Chk1. Methods Mol Biol (2011) 0.77
Methods for studying the G2 DNA damage checkpoint in mammalian cells. Methods Mol Biol (2011) 0.75