Published in Mol Biotechnol on July 01, 2013
Cholera toxin B: one subunit with many pharmaceutical applications. Toxins (Basel) (2015) 0.83
N-glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential. Sci Rep (2015) 0.81
Good manufacturing practices production of a purification-free oral cholera vaccine expressed in transgenic rice plants. Plant Cell Rep (2015) 0.78
Expression and functional validation of heat-labile enterotoxin B (LTB) and cholera toxin B (CTB) subunits in transgenic rice (Oryza sativa). Springerplus (2015) 0.77
Differential analysis of protein expression in RNA-binding-protein transgenic and parental rice seeds cultivated under salt stress. J Proteome Res (2014) 0.76
Inhibition of human MCF-7 breast cancer cells and HT-29 colon cancer cells by rice-produced recombinant human insulin-like growth binding protein-3 (rhIGFBP-3). PLoS One (2013) 0.75
N-glycan structures and downstream mannose-phosphorylation of plant recombinant human alpha-L-iduronidase: toward development of enzyme replacement therapy for mucopolysaccharidosis I. Plant Mol Biol (2017) 0.75
Sialylated endogenous glycoconjugates in plant cells. Nat Biotechnol (2003) 1.64
Salt tolerance of Arabidopsis thaliana requires maturation of N-glycosylated proteins in the Golgi apparatus. Proc Natl Acad Sci U S A (2008) 1.63
Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination. Proc Natl Acad Sci U S A (2007) 1.51
Antisense inhibition of isoamylase alters the structure of amylopectin and the physicochemical properties of starch in rice endosperm. Plant Cell Physiol (2003) 1.43
Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. Plant Biotechnol J (2004) 1.39
Characterization of a new rice glutelin gene GluD-1 expressed in the starchy endosperm. J Exp Bot (2008) 1.32
Iron accumulation does not parallel the high expression level of ferritin in transgenic rice seeds. Planta (2005) 1.32
Reducing rice seed storage protein accumulation leads to changes in nutrient quality and storage organelle formation. Plant Physiol (2010) 1.27
Replication-competent recombinant vesicular stomatitis virus encoding hepatitis C virus envelope proteins. J Virol (2007) 1.24
A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses. Proc Natl Acad Sci U S A (2005) 1.24
Compensation and interaction between RISBZ1 and RPBF during grain filling in rice. Plant J (2009) 1.23
Synergism between RPBF Dof and RISBZ1 bZIP activators in the regulation of rice seed expression genes. Plant Physiol (2006) 1.21
Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice. Plant J (2011) 1.18
Expression of ER quality control-related genes in response to changes in BiP1 levels in developing rice endosperm. Plant J (2011) 1.15
Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine. Proc Natl Acad Sci U S A (2010) 1.11
Roles of isoamylase and ADP-glucose pyrophosphorylase in starch granule synthesis in rice endosperm. Plant J (2005) 1.11
The critical role of disulfide bond formation in protein sorting in the endosperm of rice. Plant Cell (2005) 1.10
Analysis of ER stress in developing rice endosperm accumulating beta-amyloid peptide. Plant Biotechnol J (2010) 1.09
Foreign gene products can be enhanced by introduction into low storage protein mutants. Plant Biotechnol J (2003) 1.08
Overexpression of BiP has inhibitory effects on the accumulation of seed storage proteins in endosperm cells of rice. Plant Cell Physiol (2009) 1.08
Rice SPK, a calmodulin-like domain protein kinase, is required for storage product accumulation during seed development: phosphorylation of sucrose synthase is a possible factor. Plant Cell (2002) 1.07
High accumulation of bioactive peptide in transgenic rice seeds by expression of introduced multiple genes. Plant Biotechnol J (2006) 1.01
Expression of the small peptide GLP-1 in transgenic plants. Transgenic Res (2005) 1.01
Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine. Plant Biotechnol J (2005) 0.99
Cereal seed storage protein synthesis: fundamental processes for recombinant protein production in cereal grains. Plant Biotechnol J (2010) 0.99
A whole-genome analysis of a transgenic rice seed-based edible vaccine against cedar pollen allergy. DNA Res (2013) 0.98
Process development and economic evaluation of recombinant human lactoferrin expressed in rice grain. Transgenic Res (2005) 0.98
Prevention of allergic asthma by vaccination with transgenic rice seed expressing mite allergen: induction of allergen-specific oral tolerance without bystander suppression. Plant Biotechnol J (2011) 0.97
Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice. Planta (2012) 0.96
Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis. Proc Natl Acad Sci U S A (2012) 0.96
Glycosylation pattern of humanized IgG-like bispecific antibody produced by recombinant CHO cells. Appl Microbiol Biotechnol (2009) 0.95
Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR. Plant Biotechnol J (2008) 0.95
Sporophytic ovule tissues modulate the initiation and progression of apomixis in Hieracium. J Exp Bot (2012) 0.94
Generation of stable 'low phytic acid' transgenic rice through antisense repression of the 1D-myo-inositol 3-phosphate synthase gene (RINO1) using the 18-kDa oleosin promoter. Plant Biotechnol J (2008) 0.92
Rapid and scalable plant-based production of a cholera toxin B subunit variant to aid in mass vaccination against cholera outbreaks. PLoS Negl Trop Dis (2013) 0.92
A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing antibodies but does not influence pre-existing intestinal immunity. J Immunol (2009) 0.91
A rice transmembrane bZIP transcription factor, OsbZIP39, regulates the endoplasmic reticulum stress response. Plant Cell Physiol (2011) 0.91
Transgenic rice seed synthesizing diverse flavonoids at high levels: a new platform for flavonoid production with associated health benefits. Plant Biotechnol J (2013) 0.90
Rice seed ER-derived protein body as an efficient delivery vehicle for oral tolerogenic peptides. Peptides (2010) 0.90
Transgenic rice is a source of iron for iron-depleted rats. J Nutr (2002) 0.90
Molecular cloning and expression of two novel beta-N-acetylglucosaminidases from silkworm Bombyx mori. Biosci Biotechnol Biochem (2007) 0.89
Development of an efficient agrobacterium-mediated gene targeting system for rice and analysis of rice knockouts lacking granule-bound starch synthase (Waxy) and β1,2-xylosyltransferase. Plant Cell Physiol (2012) 0.89
Production of dengue 2 envelope domain III in plant using TMV-based vector system. Vaccine (2007) 0.89
Comparison of promoters in transgenic rice. Plant Biotechnol J (2008) 0.88
Biochemical safety evaluation of transgenic rice seeds expressing T cell epitopes of Japanese cedar pollen allergens. J Agric Food Chem (2006) 0.88
Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed. Vaccine (2008) 0.88
Functional integration between defence and IRE1-mediated ER stress response in rice. Sci Rep (2012) 0.87
Development of transgenic rice seed accumulating a major Japanese cedar pollen allergen (Cry j 1) structurally disrupted for oral immunotherapy. Plant Biotechnol J (2007) 0.87
Multiple roles of the ER stress sensor IRE1 demonstrated by gene targeting in rice. Sci Rep (2012) 0.87
Reduced immunogenicity of Arabidopsis hgl1 mutant N-glycans caused by altered accessibility of xylose and core fucose epitopes. J Biol Chem (2011) 0.86
Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats. Transgenic Res (2009) 0.86
Identification of a cis-element that mediates multiple pathways of the endoplasmic reticulum stress response in rice. Plant J (2013) 0.86
Human monoclonal antibodies broadly neutralizing against influenza B virus. PLoS Pathog (2013) 0.86
Arabidopsis thaliana ALG3 mutant synthesizes immature oligosaccharides in the ER and accumulates unique N-glycans. Glycobiology (2010) 0.86
Emerging antigenic variants at the antigenic site Sb in pandemic A(H1N1)2009 influenza virus in Japan detected by a human monoclonal antibody. PLoS One (2013) 0.86
Increased lysine content in rice grains by over-accumulation of BiP in the endosperm. Biosci Biotechnol Biochem (2010) 0.85
Two Arabidopsis thaliana Golgi alpha-mannosidase I enzymes are responsible for plant N-glycan maturation. Glycobiology (2009) 0.85
Arabidopsis β1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway. J Biosci Bioeng (2011) 0.84
Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site. Plant Biotechnol J (2012) 0.84
Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralising immunity. Vaccine (2009) 0.84
Agrobacterium-mediated transformation of a low glutelin mutant of 'Koshihikari' rice variety using the mutated-acetolactate synthase gene derived from rice genome as a selectable marker. Plant Cell Rep (2007) 0.84
Differential effects of a transgene to confer low phytic acid in caryopses located at different positions in rice panicles. Plant Cell Physiol (2009) 0.84
Oral immunotherapy with transgenic rice seed containing destructed Japanese cedar pollen allergens, Cry j 1 and Cry j 2, against Japanese cedar pollinosis. Plant Biotechnol J (2012) 0.84
RNA silencing induced by an artificial sequence that prevents proper transcription termination in rice. Plant Physiol (2012) 0.83
Transgenic rice seeds accumulating recombinant hypoallergenic birch pollen allergen Bet v 1 generate giant protein bodies. Plant Cell Physiol (2013) 0.83
Enhancement of sialylation on humanized IgG-like bispecific antibody by overexpression of α2,6-sialyltransferase derived from Chinese hamster ovary cells. Appl Microbiol Biotechnol (2011) 0.83
Extraction and purification of human interleukin-10 from transgenic rice seeds. Protein Expr Purif (2010) 0.83
Expression of human CMP-N-acetylneuraminic acid synthetase and CMP-sialic acid transporter in tobacco suspension-cultured cell. Biochem Biophys Res Commun (2005) 0.83
Secretory type of recombinant thioredoxin h induces ER stress in endosperm cells of transgenic rice. J Plant Physiol (2012) 0.83
The correlation between expression and localization of a foreign gene product in rice endosperm. Plant Cell Physiol (2006) 0.83
Cloning and characterization of a β-N-acetylglucosaminidase (BmFDL) from silkworm Bombyx mori. J Biosci Bioeng (2010) 0.82
The use of rice seeds to produce human pharmaceuticals for oral therapy. Biotechnol J (2013) 0.82
Differences in transcriptional regulatory mechanisms functioning for free lysine content and seed storage protein accumulation in rice grain. Plant Cell Physiol (2010) 0.82
Dengue virus neutralization and antibody-dependent enhancement activities of human monoclonal antibodies derived from dengue patients at acute phase of secondary infection. Antiviral Res (2013) 0.81
Promoter shuffling at a nuclear gene for mitochondrial RPL27. Involvement of interchromosome and subsequent intrachromosome recombinations. Plant Physiol (2006) 0.81
Double-knockout of putative endo-β-N-acetylglucosaminidase (ENGase) genes in Arabidopsis thaliana: loss of ENGase activity induced accumulation of high-mannose type free N-glycans bearing N,N'-acetylchitobiosyl unit. Biosci Biotechnol Biochem (2011) 0.81
Regulation of aspartokinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase and dihydrodipicolinate reductase in Lactobacillus plantarum. Microbiology (2006) 0.81
Expression of hypoallergenic Der f 2 derivatives with altered intramolecular disulphide bonds induces the formation of novel ER-derived protein bodies in transgenic rice seeds. J Exp Bot (2012) 0.81
Allergenic potential of rice-pollen proteins: expression, immuno-cross reactivity and IgE-binding. J Biochem (2013) 0.80
Molecular cloning and gene expression analysis of tomato endo-beta-N-acetylglucosaminidase, an endoglycosidase involved in the production of high-mannose type free N-glycans during tomato fruit ripening. Biosci Biotechnol Biochem (2009) 0.80
Analysis of rice ER-resident J-proteins reveals diversity and functional differentiation of the ER-resident Hsp70 system in plants. J Exp Bot (2013) 0.80
Production of different glycosylation variants of the tumour-targeting mAb H10 in Nicotiana benthamiana: influence on expression yield and antibody degradation. Transgenic Res (2012) 0.80
O-glycosylation of protein subpopulations in alcohol-extracted rice proteins. J Plant Physiol (2008) 0.80
Agrobacterium-mediated co-transformation of rice using two selectable marker genes derived from rice genome components. Plant Cell Rep (2012) 0.80
Antihypertensive activity of transgenic rice seed containing an 18-repeat novokinin peptide localized in the nucleolus of endosperm cells. Plant Biotechnol J (2010) 0.80
Vaccination with transgenic rice seed expressing mite allergen: a new option for asthma sufferers? Expert Rev Vaccines (2011) 0.79
Production of Ascaris suum As14 protein and its fusion protein with cholera toxin B subunit in rice seeds. J Vet Med Sci (2009) 0.79
Marker-free gene targeting by recombinase-mediated cassette exchange. Methods Mol Biol (2012) 0.79
Analysis of CMP-sialic acid transporter-like proteins in plants. Phytochemistry (2009) 0.79
Plant cultured cells expressing human beta1,4-galactosyltransferase secrete glycoproteins with galactose-extended N-linked glycans. Glycobiology (2002) 0.79
Cloning and characterization of cytidine monophosphate-3-deoxy-d-manno-octulosonate synthetase from Arabidopsis thaliana. J Biosci Bioeng (2009) 0.79
ER stress response induced by the production of human IL-7 in rice endosperm cells. Plant Mol Biol (2013) 0.79
Generation of transgenic rice lines with reduced contents of multiple potential allergens using a null mutant in combination with an RNA silencing method. Plant Cell Physiol (2011) 0.78
N-terminal vacuolar sorting signal at the mouse antibody alters the N-linked glycosylation pattern in suspension-cultured tobacco BY2 cells. J Biosci Bioeng (2011) 0.78
The 3'-untranslated region of rice glutelin GluB-1 affects accumulation of heterologous protein in transgenic rice. Biotechnol Lett (2009) 0.78
Oral immunogenicity and protective efficacy in mice of transgenic rice plants producing a vaccine candidate antigen (As16) of Ascaris suum fused with cholera toxin B subunit. Transgenic Res (2008) 0.78
Aβ induces oxidative stress in senescence-accelerated (SAMP8) mice. Biosci Biotechnol Biochem (2015) 0.78
Overexpression of OsRab7B3, a small GTP-binding protein gene, enhances leaf senescence in transgenic rice. Biosci Biotechnol Biochem (2012) 0.78