Published in PLoS One on November 30, 2012
Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides. Neuropsychiatr Dis Treat (2017) 0.75
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc (2008) 62.52
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest (2002) 21.08
Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet (2008) 10.20
Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71
Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry (1999) 8.04
The 2009 schizophrenia PORT psychopharmacological treatment recommendations and summary statements. Schizophr Bull (2009) 4.69
Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci (2004) 3.86
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophr Res (2010) 3.26
Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective. Biochim Biophys Acta (2010) 3.19
The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA. Biochim Biophys Acta (1981) 2.62
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. J Lipid Res (2002) 2.28
A lipogenic diet in mice with a disruption of the stearoyl-CoA desaturase 1 gene reveals a stringent requirement of endogenous monounsaturated fatty acids for triglyceride synthesis. J Lipid Res (2001) 2.03
Short- and long-term effects of antipsychotic drug treatment on weight gain and H1 receptor expression. Psychoneuroendocrinology (2008) 1.50
Reducing olanzapine-induced weight gain side effect by using betahistine: a study in the rat model. J Psychopharmacol (2012) 1.47
A sensitive spectrophotometric assay for peroxisomal acyl-CoA oxidase. Biochem J (1985) 1.27
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? Pharmacogenomics J (2005) 1.23
Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents. Obesity (Silver Spring) (2006) 1.09
Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions. Curr Drug Metab (2008) 1.08
Clozapine and olanzapine are associated with food craving and binge eating: results from a randomized double-blind study. J Clin Psychopharmacol (2007) 1.07
Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents. Schizophr Bull (2010) 1.06
A parametric analysis of olanzapine-induced weight gain in female rats. Psychopharmacology (Berl) (2005) 1.04
Alterations of lipid metabolism and gene expression in rat adipocytes during chronic olanzapine treatment. Mol Psychiatry (2007) 1.01
Chronic treatment with antipsychotics in rats as a model for antipsychotic-induced weight gain in human. Pharmacol Biochem Behav (2003) 1.00
Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators. Eur J Biochem (1984) 1.00
Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment. J Psychiatry Neurosci (2007) 0.99
SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects? Mol Cell Biochem (2006) 0.99
An animal model of antipsychotic-induced weight gain. Behav Brain Res (2004) 0.97
The role of thermogenesis in antipsychotic drug-induced weight gain. Obesity (Silver Spring) (2008) 0.97
Dyslipidemia independent of body mass in antipsychotic-treated patients under real-life conditions. J Clin Psychopharmacol (2008) 0.95
The distinct effects of subchronic antipsychotic drug treatment on macronutrient selection, body weight, adiposity, and metabolism in female rats. Psychopharmacology (Berl) (2007) 0.95
Atypical antipsychotic drugs induce derangements in glucose homeostasis by acutely increasing glucagon secretion and hepatic glucose output in the rat. Diabetologia (2008) 0.93
Adiposity and eating behaviors in patients under second generation antipsychotics. Obesity (Silver Spring) (2008) 0.91
Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs. BMC Neurosci (2006) 0.91
On the mechanism of the hypolipidemic effect of sulfur-substituted hexadecanedioic acid (3-thiadicarboxylic acid) in normolipidemic rats. J Lipid Res (1993) 0.90
Insulin resistance and secretion in vivo: effects of different antipsychotics in an animal model. Schizophr Res (2009) 0.90
Characterization of olanzapine-induced weight gain in rats. J Psychopharmacol (2002) 0.89
Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. Psychopharmacology (Berl) (2011) 0.89
Effects of long-term administration of clozapine on body weight and food intake in rats. Pharmacol Biochem Behav (1993) 0.87
Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. Int J Neuropsychopharmacol (2011) 0.87
Hyperphagia and increased meal size are responsible for weight gain in rats treated sub-chronically with olanzapine. Psychopharmacology (Berl) (2008) 0.86
Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity. Schizophr Res (2011) 0.85
Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids). Pharmacol Ther (1994) 0.85
Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes Obes Metab (2009) 0.85
Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot study. Scand J Clin Lab Invest (2011) 0.84
Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase. Pharmacol Res (2012) 0.84
Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. J Lipid Res (1998) 0.82
The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats. Chem Biol Interact (2008) 0.81
Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes Obes Metab (2009) 0.80
Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats. Psychopharmacology (Berl) (2005) 0.80
Ziprasidone and aripiprazole attenuate olanzapine-induced hyperphagia in rats. J Psychopharmacol (2008) 0.80
Hepatic fatty acid metabolism as a determinant of plasma and liver triacylglycerol levels. Studies on tetradecylthioacetic and tetradecylthiopropionic acids. Eur J Biochem (1995) 0.79
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis. Proc Natl Acad Sci U S A (2013) 1.34
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes (2012) 1.28
Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. Pediatrics (2008) 1.18
An 8.9 Mb 19p13 duplication associated with precocious puberty and a sporadic 3.9 Mb 2q23.3q24.1 deletion containing NR4A2 in mentally retarded members of a family with an intrachromosomal 19p-into-19q between-arm insertion. Eur J Hum Genet (2009) 1.11
Excretion of methylphenidate in breast milk. Am J Psychiatry (2007) 1.07
Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neurosci Lett (2005) 1.05
The brain and brown fat. Ann Med (2014) 1.02
Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. Eur J Nutr (2012) 1.01
Hypothalamic lipotoxicity and the metabolic syndrome. Biochim Biophys Acta (2009) 1.00
SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: relevance for metabolic side-effects? Mol Cell Biochem (2006) 0.99
Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. Int J Neuropsychopharmacol (2008) 0.98
Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats. Scand J Gastroenterol (2011) 0.95
Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. J Psychopharmacol (2010) 0.94
Causes and prevention of tamoxifen-induced accumulation of triacylglycerol in rat liver. J Lipid Res (2006) 0.93
Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. BMC Pharmacol (2009) 0.93
A complex role of activin A in non-alcoholic fatty liver disease. Am J Gastroenterol (2009) 0.92
Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. Endocrinology (2014) 0.90
Disturbed carnitine regulation in chronic heart failure--increased plasma levels of palmitoyl-carnitine are associated with poor prognosis. Int J Cardiol (2012) 0.89
Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. Psychopharmacology (Berl) (2011) 0.89
Krill powder increases liver lipid catabolism and reduces glucose mobilization in tumor necrosis factor-alpha transgenic mice fed a high-fat diet. Metabolism (2012) 0.87
Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. Int J Neuropsychopharmacol (2011) 0.87
Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes. FASEB J (2002) 0.86
Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks. J Nutr Biochem (2012) 0.86
Dietary supplementation of herring roe and milt enhances hepatic fatty acid catabolism in female mice transgenic for hTNFα. Eur J Nutr (2011) 0.85
Long-term treatment with the pan-PPAR agonist tetradecylthioacetic acid or fish oil is associated with increased cardiac content of n-3 fatty acids in rat. Lipids Health Dis (2012) 0.84
Anti-inflammatory and hypolipidemic effects of the modified fatty acid tetradecylthioacetic acid in psoriasis--a pilot study. Scand J Clin Lab Invest (2011) 0.84
Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation. J Lipid Res (2003) 0.84
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation. Lipids Health Dis (2013) 0.83
Hypolipidemic effect of dietary water-soluble protein extract from chicken: impact on genes regulating hepatic lipid and bile acid metabolism. Eur J Nutr (2014) 0.83
Participation of phospholipase D and alpha/beta-protein kinase C in growth factor-induced signalling in C3H10T1/2 fibroblasts. Biochim Biophys Acta (2003) 0.82
Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease. Cardiol Res Pract (2012) 0.82
The metabolic effects of thia fatty acids in rat liver depend on the position of the sulfur atom. Chem Biol Interact (2005) 0.82
Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells. Chem Biol (2003) 0.82
Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats. Nutrition (2008) 0.82
Phospholipids from herring roe improve plasma lipids and glucose tolerance in healthy, young adults. Lipids Health Dis (2014) 0.81
Free carnitine and acylcarnitines in obese patients with polycystic ovary syndrome and effects of pioglitazone treatment. Fertil Steril (2012) 0.81
The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats. Chem Biol Interact (2008) 0.81
A casein diet added isoflavone-enriched soy protein favorably affects biomarkers of steatohepatitis in obese Zucker rats. Nutrition (2008) 0.81
Salmon diet in patients with active ulcerative colitis reduced the simple clinical colitis activity index and increased the anti-inflammatory fatty acid index--a pilot study. Scand J Clin Lab Invest (2010) 0.80
Lipogenic effects of psychotropic drugs: focus on the SREBP system. Front Biosci (Landmark Ed) (2011) 0.80
Proteomics identifies molecular networks affected by tetradecylthioacetic acid and fish oil supplemented diets. J Proteomics (2013) 0.79
Fish oil and the pan-PPAR agonist tetradecylthioacetic acid affect the amino acid and carnitine metabolism in rats. PLoS One (2013) 0.79
Tissue-specific effects of bariatric surgery including mitochondrial function. J Obes (2011) 0.79
Modified fatty acids and their possible therapeutic targets in malignant diseases. Expert Opin Ther Targets (2003) 0.78
Inhibition of rat lipoprotein oxidation after tetradecylthioacetic acid feeding. Biochem Pharmacol (2002) 0.78
Tetradecylthioacetic acid increases hepatic mitochondrial β-oxidation and alters fatty acid composition in a mouse model of chronic inflammation. Lipids (2011) 0.78
Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats. Drug Metab Lett (2008) 0.78
Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-CoA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. Endocrinology (2014) 0.77
Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition? J Lipid Res (2012) 0.77
Effects of local delivery of tetradecylthioacetic acid within the injured coronary vessel wall. Scand Cardiovasc J (2012) 0.77
An immunomodulating fatty acid analogue targeting mitochondria exerts anti-atherosclerotic effect beyond plasma cholesterol-lowering activity in apoe(-/-) mice. PLoS One (2013) 0.77
Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. Int J Neuropsychopharmacol (2013) 0.76
Skeletal effects of the saturated 3-thia Fatty Acid tetradecylthioacetic Acid in rats. PPAR Res (2011) 0.75
Corrigendum: Hepatic p63 regulates steatosis via IKKβ/ER stress. Nat Commun (2017) 0.75
Tetradecylthioacetic acid increases fat metabolism and improves cardiac function in experimental heart failure. Lipids (2012) 0.75
Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance. Neuroendocrinology (2016) 0.75
[Paramethoxymethamphetamine]. Tidsskr Nor Laegeforen (2011) 0.75
Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. Am J Physiol Renal Physiol (2007) 0.75
Synthesis and analysis of novel glycerolipids for the treatment of metabolic syndrome. J Med Chem (2009) 0.75
Transfer of aripiprazole to breast milk: a case report. J Clin Psychopharmacol (2014) 0.75
Synthetic cannabis. Tidsskr Nor Laegeforen (2012) 0.75
Nuclear import of factors involved in signaling is inhibited in C3H/10T1/2 cells treated with tetradecylthioacetic acid. J Lipid Res (2002) 0.75
[A bottle with unknown content]. Tidsskr Nor Laegeforen (2011) 0.75
Skin permeation of acyl derivatives of stobadine. Drug Deliv (2006) 0.75
Dietary single cell protein reduces fatty liver in obese Zucker rats. Br J Nutr (2008) 0.75