Published in Genetics on April 01, 1990
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A haplotype at STAT2 Introgressed from neanderthals and serves as a candidate of positive selection in Papua New Guinea. Am J Hum Genet (2012) 1.15
Nucleotide polymorphism and natural selection at the pantophysin (Pan I) locus in the Atlantic cod, Gadus morhua (L.). Genetics (2001) 1.13
Inter- and intralocus recombination drive MHC class IIB gene diversification in a teleost, the three-spined stickleback Gasterosteus aculeatus. J Mol Evol (2005) 1.13
MHC standing genetic variation and pathogen resistance in wild Atlantic salmon. Philos Trans R Soc Lond B Biol Sci (2009) 1.11
Recombination, balancing selection and phylogenies in MHC and self-incompatibility genes. Genetics (2001) 1.10
An ancient mitochondrial polymorphism in Adalis bipunctata linked to a sex-ratio-distorting bacterium. Genetics (2005) 1.09
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A model-based approach for identifying signatures of ancient balancing selection in genetic data. PLoS Genet (2014) 1.07
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Distinct evolutionary strategies of human leucocyte antigen loci in pathogen-rich environments. Philos Trans R Soc Lond B Biol Sci (2012) 1.02
Geographic heterogeneity in natural selection on an MHC locus in sockeye salmon. Genetica (2001) 1.02
Single locus typing of MHC class I and class II B loci in a population of red jungle fowl. Immunogenetics (2008) 1.02
Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types. Proc Natl Acad Sci U S A (2012) 1.01
Polymorphism at the apical membrane antigen 1 locus reflects the world population history of Plasmodium vivax. BMC Evol Biol (2008) 0.98
Evolutionary analysis of classical HLA class I and II genes suggests that recent positive selection acted on DPB1*04:01 in Japanese population. PLoS One (2012) 0.98
Selection, diversity and evolutionary patterns of the MHC class II DAB in free-ranging Neotropical marsupials. BMC Genet (2008) 0.98
Pervasive recombination and sympatric genome diversification driven by frequency-dependent selection in Borrelia burgdorferi, the Lyme disease bacterium. Genetics (2011) 0.97
Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures. BMC Med Genet (2003) 0.97
Major histocompatibility complex monomorphism and low levels of DNA fingerprinting variability in a reintroduced and rapidly expanding population of beavers. Proc Natl Acad Sci U S A (1993) 0.96
The major histocompatibility complex (Mhc) class IIB region has greater genomic structural flexibility and diversity in the quail than the chicken. BMC Genomics (2006) 0.95
Low MHC variation in the endangered Galápagos penguin (Spheniscus mendiculus). Immunogenetics (2007) 0.94
Selection, hitchhiking and disequilibrium analysis at three linked loci with application to HLA data. Genetics (1991) 0.94
Bottleneck effects on vaccine-candidate antigen diversity of malaria parasites in Thailand. Vaccine (2010) 0.94
Mhc supertypes confer both qualitative and quantitative resistance to avian malaria infections in a wild bird population. Proc Biol Sci (2013) 0.93
Levels of DNA polymorphism and divergence yield important insights into evolutionary processes. Proc Natl Acad Sci U S A (1993) 0.93
Selection, trans-species polymorphism, and locus identification of major histocompatibility complex class IIβ alleles of New World ranid frogs. Immunogenetics (2010) 0.93
Duplication, balancing selection and trans-species evolution explain the high levels of polymorphism of the DQA MHC class II gene in voles (Arvicolinae). Immunogenetics (2006) 0.93
Balancing selection at a frog antimicrobial peptide locus: fluctuating immune effector alleles? Mol Biol Evol (2008) 0.92
Major histocompatibility complex controls the trajectory but not host-specific adaptation during virulence evolution of the pathogenic fungus Cryptococcus neoformans. Proc Biol Sci (2004) 0.92
Possible diversifying selection in the imprinted gene, MEDEA, in Arabidopsis. Mol Biol Evol (2009) 0.91
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Low major histocompatibility complex class II diversity in European and North American moose. Proc Natl Acad Sci U S A (1995) 0.91
Differential selective pressures on the merozoite surface protein 2 locus of Plasmodium falciparum in a low endemic area. Gene (2008) 0.91
Adaptive molecular evolution of the Major Histocompatibility Complex genes, DRA and DQA, in the genus Equus. BMC Evol Biol (2011) 0.91
Signals of major histocompatibility complex overdominance in a wild salmonid population. Proc Biol Sci (2009) 0.89
Natural selection maintains a stable polymorphism at the circumsporozoite protein locus of Plasmodium falciparum in a low endemic area. Infect Genet Evol (2009) 0.89
Recent and ancient signature of balancing selection around the S-locus in Arabidopsis halleri and A. lyrata. Mol Biol Evol (2012) 0.89
An asymmetric model of heterozygote advantage at major histocompatibility complex genes: degenerate pathogen recognition and intersection advantage. Genetics (2008) 0.89
HLA-associated susceptibility to childhood B-cell precursor ALL: definition and role of HLA-DPB1 supertypes. Br J Cancer (2008) 0.88
Characterising functionally important and ecologically meaningful genetic diversity using a candidate gene approach. Genetica (2008) 0.88
Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus). BMC Evol Biol (2009) 0.88
Candidate gene approach for parasite resistance in sheep--variation in immune pathway genes and association with fecal egg count. PLoS One (2014) 0.87
Notes on individual sequence variation in humans: immunoglobulin kappa light chain. Am J Hum Genet (1994) 0.87
Sexual selection and the evolutionary dynamics of the major histocompatibility complex. Proc Biol Sci (2014) 0.87
Frequent segmental sequence exchanges and rapid gene duplication characterize the MHC class I genes in lemurs. Immunogenetics (2003) 0.87
MHC allele frequency distributions under parasite-driven selection: A simulation model. BMC Evol Biol (2010) 0.86
Trans-species polymorphism and evidence of selection on class II MHC loci in tuco-tucos (Rodentia: Ctenomyidae). Immunogenetics (2007) 0.86
Pathogen-driven selection in the human genome. Int J Evol Biol (2013) 0.85
Isolation and characterization of major histocompatibility complex (MHC) class II B genes in the Barn owl (Aves: Tyto alba). Immunogenetics (2008) 0.85
Diversifying and purifying selection in the peptide binding region of DRB in mammals. J Mol Evol (2008) 0.84
On the evolution of codon volatility. Genetics (2004) 0.84
Current perspectives on the intensity of natural selection of MHC loci. Immunogenetics (2013) 0.84
HLA supertype variation across populations: new insights into the role of natural selection in the evolution of HLA-A and HLA-B polymorphisms. Immunogenetics (2015) 0.84
Genomic data reveal a complex making of humans. PLoS Genet (2012) 0.84
Immunogenetic variation and differential pathogen exposure in free-ranging cheetahs across Namibian farmlands. PLoS One (2012) 0.84
Stepwise threshold clustering: a new method for genotyping MHC loci using next-generation sequencing technology. PLoS One (2014) 0.83
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