PubRank

Peter J Hotez

Author PubWeight™ 307.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012 56.72
2 Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012 41.47
3 Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012 26.95
4 Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 2006 15.08
5 Soil-transmitted helminth infections: updating the global picture. Trends Parasitol 2003 9.33
6 "Rapid-impact interventions": how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor. PLoS Med 2005 6.33
7 Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet 2015 6.13
8 Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. Am J Trop Med Hyg 2007 3.29
9 Global economic burden of Chagas disease: a computational simulation model. Lancet Infect Dis 2013 3.15
10 Hookworm-related anaemia among pregnant women: a systematic review. PLoS Negl Trop Dis 2008 2.77
11 Health innovation networks to help developing countries address neglected diseases. Science 2005 2.72
12 The global atlas of helminth infection: mapping the way forward in neglected tropical disease control. PLoS Negl Trop Dis 2010 2.49
13 The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren. Malar J 2006 2.45
14 Human hookworm infection in the 21st century. Adv Parasitol 2004 2.43
15 Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop 2010 2.23
16 "Manifesto" for advancing the control and elimination of neglected tropical diseases. PLoS Negl Trop Dis 2010 2.22
17 Fighting tropical diseases. Science 2006 2.09
18 Waging peace through neglected tropical disease control: a US foreign policy for the bottom billion. PLoS Negl Trop Dis 2009 2.03
19 Chagas disease: "the new HIV/AIDS of the Americas". PLoS Negl Trop Dis 2012 1.92
20 Schistosomiasis in Africa: an emerging tragedy in our new global health decade. PLoS Negl Trop Dis 2009 1.72
21 Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. Int J Parasitol 2006 1.69
22 Africa's 32 cents solution for HIV/AIDS. PLoS Negl Trop Dis 2009 1.68
23 Cures for the Third World's problems: the application of genomics to the diseases plaguing the developing world may have huge medical and economic benefits for those countries and might even prevent armed conflict. EMBO Rep 2002 1.66
24 Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Trop Med Int Health 2006 1.61
25 Vaccines to combat the neglected tropical diseases. Immunol Rev 2011 1.55
26 The neglected tropical diseases of India and South Asia: review of their prevalence, distribution, and control or elimination. PLoS Negl Trop Dis 2011 1.52
27 Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance? PLoS Negl Trop Dis 2009 1.49
28 Digestive proteases of blood-feeding nematodes. Trends Parasitol 2003 1.48
29 Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt. Liver Int 2013 1.47
30 Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J 2005 1.44
31 Neglected tropical diseases and the Global Fund. Lancet 2009 1.44
32 Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clin Infect Dis 2002 1.42
33 A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J Biol Chem 2004 1.41
34 X-ray structure of Na-ASP-2, a pathogenesis-related-1 protein from the nematode parasite, Necator americanus, and a vaccine antigen for human hookworm infection. J Mol Biol 2005 1.40
35 Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg 2006 1.40
36 Rabies, still neglected after 125 years of vaccination. PLoS Negl Trop Dis 2010 1.36
37 Which new approaches to tackling neglected tropical diseases show promise? PLoS Med 2010 1.34
38 The neglected tropical diseases and their devastating health and economic impact on the member nations of the Organisation of the Islamic Conference. PLoS Negl Trop Dis 2009 1.33
39 Meeting cholera's challenge to Haiti and the world: a joint statement on cholera prevention and care. PLoS Negl Trop Dis 2011 1.33
40 Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. PLoS Negl Trop Dis 2012 1.30
41 Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine 2005 1.28
42 Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med 2005 1.26
43 Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Adv Parasitol 2011 1.25
44 Ready to put metadata on the post-2015 development agenda? Linking data publications to responsible innovation and science diplomacy. OMICS 2014 1.24
45 Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. J Infect Dis 2004 1.24
46 Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis 2013 1.23
47 Hookworm vaccines. Clin Infect Dis 2008 1.23
48 One world health: neglected tropical diseases in a flat world. PLoS Negl Trop Dis 2009 1.23
49 Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Mol Biochem Parasitol 2003 1.21
50 The contribution of mass drug administration to global health: past, present and future. Philos Trans R Soc Lond B Biol Sci 2014 1.21
51 Neglected tropical disease control in the "post-American world". PLoS Negl Trop Dis 2010 1.20
52 Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J 2002 1.20
53 Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect Immun 2005 1.18
54 The global health crisis and our nation's research universities. PLoS Negl Trop Dis 2010 1.16
55 Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. J Infect Dis 2004 1.14
56 New vaccines for neglected parasitic diseases and dengue. Transl Res 2013 1.13
57 A national cholera vaccine stockpile--a new humanitarian and diplomatic resource. N Engl J Med 2010 1.13
58 Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. PLoS Negl Trop Dis 2013 1.13
59 Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. Int J Parasitol 2003 1.10
60 Empowering women and improving female reproductive health through control of neglected tropical diseases. PLoS Negl Trop Dis 2009 1.10
61 Tropical anemia: one of Africa's great killers and a rationale for linking malaria and neglected tropical disease control to achieve a common goal. PLoS Negl Trop Dis 2008 1.09
62 New antipoverty drugs, vaccines, and diagnostics: a research agenda for the US President's Global Health Initiative (GHI). PLoS Negl Trop Dis 2011 1.08
63 NTDs in the heart of darkness: the Democratic Republic of Congo's unknown burden of neglected tropical diseases. PLoS Negl Trop Dis 2013 1.07
64 A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Mol Biochem Parasitol 2002 1.07
65 Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine 2005 1.06
66 Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. J Infect Dis 2010 1.06
67 Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J Allergy Clin Immunol 2012 1.05
68 Nuclear weapons and neglected diseases: the "ten-thousand-to-one gap". PLoS Negl Trop Dis 2010 1.05
69 An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases. Expert Rev Vaccines 2006 1.05
70 Neglected diseases and poverty in "The Other America": the greatest health disparity in the United States? PLoS Negl Trop Dis 2007 1.05
71 A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol 2004 1.05
72 Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infect Immun 2006 1.04
73 Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases. PLoS Negl Trop Dis 2012 1.04
74 Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine 2008 1.04
75 Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasit Vectors 2014 1.04
76 Stigma: the stealth weapon of the NTD. PLoS Negl Trop Dis 2008 1.03
77 The giant anteater in the room: Brazil's neglected tropical diseases problem. PLoS Negl Trop Dis 2008 1.03
78 Modeling the economic value of a Chagas' disease therapeutic vaccine. Hum Vaccin Immunother 2012 1.02
79 The CNCDs and the NTDs: blurring the lines dividing noncommunicable and communicable chronic diseases. PLoS Negl Trop Dis 2008 1.02
80 Neglected tropical diseases as hidden causes of cardiovascular disease. PLoS Negl Trop Dis 2012 1.01
81 Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Negl Trop Dis 2012 1.01
82 An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J 2009 1.01
83 Engaging a rising China through neglected tropical diseases. PLoS Negl Trop Dis 2012 1.01
84 X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. BMC Struct Biol 2007 1.00
85 The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. J Infect Dis 2005 1.00
86 Peace through vaccine diplomacy. Science 2010 0.99
87 A Global Fund to Fight Neglected Tropical Diseases: is the G8 Hokkaido Toyako 2008 Summit ready? PLoS Negl Trop Dis 2008 0.99
88 A history of hookworm vaccine development. Hum Vaccin 2011 0.99
89 Vaccinomics for the major blood feeding helminths of humans. OMICS 2011 0.99
90 Turning neglected tropical diseases into forgotten maladies. Health Aff (Millwood) 2009 0.98
91 Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine 2005 0.97
92 Neglected tropical diseases in the Catholic world. PLoS Negl Trop Dis 2011 0.97
93 Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. Am J Trop Med Hyg 2002 0.97
94 Childhood parasitic infections endemic to the United States. Pediatr Clin North Am 2013 0.96
95 Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. Int J Parasitol 2003 0.96
96 Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas. PLoS Negl Trop Dis 2013 0.95
97 The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas. Vaccine 2012 0.95
98 Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif 2012 0.94
99 Global trends in neglected tropical disease control and elimination: impact on child health. Arch Dis Child 2013 0.94
100 Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J Infect Dis 2003 0.94
101 Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy. OMICS 2013 0.92
102 Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster. Infect Immun 2005 0.92
103 Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome. Expert Rev Vaccines 2012 0.92
104 Holidays in the sun and the Caribbean's forgotten burden of neglected tropical diseases. PLoS Negl Trop Dis 2008 0.91
105 Central Asia's hidden burden of neglected tropical diseases. PLoS Negl Trop Dis 2011 0.91
106 Break Out: urogenital schistosomiasis and Schistosoma haematobium infection in the post-genomic era. PLoS Negl Trop Dis 2013 0.91
107 America's most distressed areas and their neglected infections: the United States Gulf Coast and the District of Columbia. PLoS Negl Trop Dis 2011 0.91
108 The intestinal protozoa: emerging impact on global health and development. Curr Opin Gastroenterol 2015 0.90
109 Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Hum Vaccin Immunother 2012 0.90
110 A new European neglected diseases center for Greece? PLoS Negl Trop Dis 2013 0.89
111 Linking global HIV/AIDS treatments with national programs for the control and elimination of the neglected tropical diseases. PLoS Negl Trop Dis 2011 0.89
112 Unleashing "civilian power": a new American diplomacy through neglected tropical disease control, elimination, research, and development. PLoS Negl Trop Dis 2011 0.88
113 A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biochem Parasitol 2008 0.88
114 Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. Int J Parasitol 2004 0.87
115 Neglected tropical diseases and HIV/AIDS. Lancet 2006 0.87
116 Crystallization and preliminary X-ray analysis of Na-ASP-1, a multi-domain pathogenesis-related-1 protein from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.86
117 Global progress towards eliminating gastrointestinal helminth infections. Curr Opin Gastroenterol 2014 0.86
118 Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Rev Vaccines 2010 0.85
119 An interfaith dialogue on the neglected tropical diseases. PLoS Negl Trop Dis 2011 0.84
120 The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress. J Nutr 2013 0.83
121 Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Hum Vaccin Immunother 2013 0.82
122 Fighting neglected tropical diseases in the southern United States. BMJ 2012 0.82
123 Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Hum Vaccin Immunother 2014 0.82
124 The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology 2011 0.81
125 Reinventing Guantanamo: from detainee facility to Center for Research on Neglected Diseases of Poverty in the Americas. PLoS Negl Trop Dis 2008 0.81
126 Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Rev Vaccines 2014 0.80
127 Neglected parasitic infections in the United States: needs and opportunities. Am J Trop Med Hyg 2014 0.80
128 The unfinished public health agenda of chagas disease in the era of globalization. PLoS Negl Trop Dis 2009 0.80
129 Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology 2011 0.79
130 Tropical diseases research: thirty years and counting. PLoS Negl Trop Dis 2008 0.79
131 Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Exp Parasitol 2003 0.79
132 Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol Biochem Parasitol 2002 0.79
133 Glaucomics: a call for systems diagnostics for 21(st) century ophthalmology and personalized visual health. OMICS 2014 0.78
134 Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods Mol Biol 2007 0.78
135 Expression, purification, and characterization of the Necator americanus aspartic protease-1 (Na-APR-1 (M74)) antigen, a component of the bivalent human hookworm vaccine. Hum Vaccin Immunother 2015 0.77
136 Neglected tropical diseases and the 2012 US presidential election. PLoS Negl Trop Dis 2011 0.75
137 Now we are six. PLoS Negl Trop Dis 2012 0.75
138 New tools for NTD vaccines: A case study of quality control assays for product development of the human hookworm vaccine Na-APR-1M74. Hum Vaccin Immunother 2015 0.75
139 Crystallization and preliminary X-ray analysis of Na-SAA-2 from the human hookworm parasite Necator americanus. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.75
140 Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Hum Vaccin Immunother 2013 0.75
141 Correction: Blue Marble Health Redux: Neglected Tropical Diseases and Human Development in the Group of 20 (G20) Nations and Nigeria. PLoS Negl Trop Dis 2015 0.75