Published in Science on December 20, 2012
Bats are a major natural reservoir for hepaciviruses and pegiviruses. Proc Natl Acad Sci U S A (2013) 1.93
Filoviruses in bats: current knowledge and future directions. Viruses (2014) 1.79
Genome-wide signatures of convergent evolution in echolocating mammals. Nature (2013) 1.59
Comparative genetics of longevity and cancer: insights from long-lived rodents. Nat Rev Genet (2014) 1.58
Ecological dynamics of emerging bat virus spillover. Proc Biol Sci (2015) 1.34
Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. Nat Commun (2013) 1.31
Ecology and mode-of-life explain lifespan variation in birds and mammals. Proc Biol Sci (2014) 1.31
Bat flight and zoonotic viruses. Emerg Infect Dis (2014) 1.17
Bats as reservoir hosts of human bacterial pathogen, Bartonella mayotimonensis. Emerg Infect Dis (2014) 1.15
A case for the ancient origin of coronaviruses. J Virol (2013) 1.12
High diversity of West African bat malaria parasites and a tight link with rodent Plasmodium taxa. Proc Natl Acad Sci U S A (2013) 1.11
Patterns of positive selection in seven ant genomes. Mol Biol Evol (2014) 1.08
What bats have to say about speech and language. Psychon Bull Rev (2017) 1.06
The Merkel cell polyomavirus minor capsid protein. PLoS Pathog (2013) 1.01
Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL-mediated apoptosis. Genome Biol (2014) 0.98
Bats and viruses: friend or foe? PLoS Pathog (2013) 0.97
Identification of diverse full-length endogenous betaretroviruses in megabats and microbats. Retrovirology (2013) 0.96
From SARS coronavirus to novel animal and human coronaviruses. J Thorac Dis (2013) 0.96
Rolling-circle transposons catalyze genomic innovation in a mammalian lineage. Genome Biol Evol (2014) 0.95
Comparative transcriptome analyses reveal core parasitism genes and suggest gene duplication and repurposing as sources of structural novelty. Mol Biol Evol (2014) 0.93
Hypoxia adaptations in the grey wolf (Canis lupus chanco) from Qinghai-Tibet Plateau. PLoS Genet (2014) 0.90
Reservoir host immune responses to emerging zoonotic viruses. Cell (2014) 0.90
Influenza A virus polymerase is a site for adaptive changes during experimental evolution in bat cells. J Virol (2014) 0.89
Genome-wide characterization of endogenous retroviruses in the bat Myotis lucifugus reveals recent and diverse infections. J Virol (2013) 0.88
Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats. Proc Natl Acad Sci U S A (2016) 0.87
Role of BRCA1 in brain development. Proc Natl Acad Sci U S A (2014) 0.87
Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses? Mem Inst Oswaldo Cruz (2015) 0.87
IRF7 in the Australian black flying fox, Pteropus alecto: evidence for a unique expression pattern and functional conservation. PLoS One (2014) 0.86
Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage. Proc Natl Acad Sci U S A (2014) 0.86
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty. Genome Biol Evol (2013) 0.85
The White-Nose Syndrome Transcriptome: Activation of Anti-fungal Host Responses in Wing Tissue of Hibernating Little Brown Myotis. PLoS Pathog (2015) 0.85
Towards the identification of the loci of adaptive evolution. Methods Ecol Evol (2015) 0.85
Genome-wide survey of the seagrass Zostera muelleri suggests modification of the ethylene signalling network. J Exp Bot (2015) 0.84
From the ultrasonic to the infrared: molecular evolution and the sensory biology of bats. Front Physiol (2013) 0.83
Evolutionary histories of transposable elements in the genome of the largest living marsupial carnivore, the Tasmanian devil. Mol Biol Evol (2015) 0.82
Immunology of bats and their viruses: challenges and opportunities. Viruses (2014) 0.82
Transmission or Within-Host Dynamics Driving Pulses of Zoonotic Viruses in Reservoir-Host Populations. PLoS Negl Trop Dis (2016) 0.81
Transcriptomic and epigenomic characterization of the developing bat wing. Nat Genet (2016) 0.81
Adaptive evolution of the Hox gene family for development in bats and dolphins. PLoS One (2013) 0.81
OASes and STING: adaptive evolution in concert. Genome Biol Evol (2015) 0.81
Naked but not Hairless: the pitfalls of analyses of molecular adaptation based on few genome sequence comparisons. Genome Biol Evol (2015) 0.80
Cross-Species Transmission and Differential Fate of an Endogenous Retrovirus in Three Mammal Lineages. PLoS Pathog (2015) 0.80
Vampire bats exhibit evolutionary reduction of bitter taste receptor genes common to other bats. Proc Biol Sci (2014) 0.80
Frequent loss and alteration of the MOXD2 gene in catarrhines and whales: a possible connection with the evolution of olfaction. PLoS One (2014) 0.80
Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus. PLoS Genet (2016) 0.80
No fever and leucocytosis in response to a lipopolysaccharide challenge in an insectivorous bat. Biol Lett (2015) 0.79
Bat and pig IFN-induced transmembrane protein 3 restrict cell entry by influenza virus and lyssaviruses. J Gen Virol (2015) 0.79
Endless paces of degeneration--applying comparative genomics to study evolution's moulding of longevity. EMBO Rep (2013) 0.79
Comparative inner ear transcriptome analysis between the Rickett's big-footed bats (Myotis ricketti) and the greater short-nosed fruit bats (Cynopterus sphinx). BMC Genomics (2013) 0.78
How and why overcome the impediments to resolution: lessons from rhinolophid and hipposiderid bats. Mol Biol Evol (2014) 0.78
Evolutionary history of chordate PAX genes: dynamics of change in a complex gene family. PLoS One (2013) 0.78
Deep landscape update of dispersed and tandem repeats in the genome model of the red jungle fowl, Gallus gallus, using a series of de novo investigating tools. BMC Genomics (2016) 0.78
Evolution and comparative analysis of the bat MHC-I region. Sci Rep (2016) 0.78
Unique Loss of the PYHIN Gene Family in Bats Amongst Mammals: Implications for Inflammasome Sensing. Sci Rep (2016) 0.78
Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line. mSphere (2016) 0.77
BGD: a database of bat genomes. PLoS One (2015) 0.77
De novo transcriptome reconstruction and annotation of the Egyptian rousette bat. BMC Genomics (2015) 0.77
Poxviruses in bats … so what? Viruses (2014) 0.77
Characterisation of novel microRNAs in the Black flying fox (Pteropus alecto) by deep sequencing. BMC Genomics (2014) 0.77
Characterization of Eptesipoxvirus, a novel poxvirus from a microchiropteran bat. Virus Genes (2017) 0.77
Molecular adaptation of telomere associated genes in mammals. BMC Evol Biol (2013) 0.76
Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat Myotis davidii. G3 (Bethesda) (2014) 0.76
Dietary and flight energetic adaptations in a salivary gland transcriptome of an insectivorous bat. PLoS One (2014) 0.76
Cellular and molecular drivers of differential organ growth: insights from the limbs of Monodelphis domestica. Dev Genes Evol (2016) 0.76
Genomic, Transcriptomic and Proteomic Analysis Provide Insights into the Cold Adaptation Mechanism of the Obligate Psychrophilic Fungus Mrakia psychrophila. G3 (Bethesda) (2016) 0.76
Genomic Mining Reveals Deep Evolutionary Relationships between Bornaviruses and Bats. Viruses (2015) 0.76
Plasma proteomic analysis of active and torpid greater mouse-eared bats (Myotis myotis). Sci Rep (2015) 0.76
Fruits of virus discovery: new pathogens and new experimental models. J Virol (2014) 0.76
Adaptive evolution of virus-sensing toll-like receptor 8 in bats. Immunogenetics (2016) 0.76
Genome-scale analysis of demographic history and adaptive selection. Protein Cell (2014) 0.75
Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax. BMC Evol Biol (2016) 0.75
Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions. J Virol (2017) 0.75
Adaptation of peroxisome proliferator-activated receptor alpha to hibernation in bats. BMC Evol Biol (2015) 0.75
Blood miRNomes and transcriptomes reveal novel longevity mechanisms in the long-lived bat, Myotis myotis. BMC Genomics (2016) 0.75
Broad and Temperature Independent Replication Potential of Filoviruses on Cells Derived From Old and New World Bat Species. J Infect Dis (2016) 0.75
Revisiting Myosin Families Through Large-scale Sequence Searches Leads to the Discovery of New Myosins. Evol Bioinform Online (2016) 0.75
Going batty: Studying natural reservoirs to inform drug development. Nat Med (2015) 0.75
Comparative Transcriptomes and EVO-DEVO Studies Depending on Next Generation Sequencing. Comput Math Methods Med (2015) 0.75
Divergent evolutionary rates in vertebrate and mammalian specific conserved non-coding elements (CNEs) in echolocating mammals. BMC Evol Biol (2014) 0.75
Discovery of a Novel Bat Gammaherpesvirus. mSphere (2016) 0.75
Insights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto. BMC Genomics (2017) 0.75
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages. Sci Rep (2016) 0.75
Proteomic analysis of Pteropus alecto kidney cells in response to the viral mimic, Poly I:C. Proteome Sci (2015) 0.75
Phenotypic and functional characterization of the major lymphocyte populations in the fruit-eating bat Pteropus alecto. Sci Rep (2016) 0.75
Analysis of cathepsin and furin proteolytic enzymes involved in viral fusion protein activation in cells of the bat reservoir host. PLoS One (2015) 0.75
Myotis rufoniger genome sequence and analyses: M. rufoniger's genomic feature and the decreasing effective population size of Myotis bats. PLoS One (2017) 0.75
Small subunit ribosomal metabarcoding reveals extraordinary trypanosomatid diversity in Brazilian bats. PLoS Negl Trop Dis (2017) 0.75
The bat genome: GC-biased small chromosomes associated with reduction in genome size. Chromosoma (2013) 0.75
Selective evolution of Toll-like receptors 3, 7, 8, and 9 in bats. Immunogenetics (2016) 0.75
Immunological Control of Viral Infections in Bats and the Emergence of Viruses Highly Pathogenic to Humans. Front Immunol (2017) 0.75
IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection. PLoS One (2017) 0.75
Transcriptomic Signatures of Tacaribe Virus-Infected Jamaican Fruit Bats. mSphere (2017) 0.75
SOAP: short oligonucleotide alignment program. Bioinformatics (2008) 68.13
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
De novo assembly of human genomes with massively parallel short read sequencing. Genome Res (2009) 45.91
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
SOAP2: an improved ultrafast tool for short read alignment. Bioinformatics (2009) 39.47
Enterotypes of the human gut microbiome. Nature (2011) 24.36
SOAPdenovo2: an empirically improved memory-efficient short-read de novo assembler. Gigascience (2012) 20.89
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res (2008) 20.59
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A (2002) 20.48
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Res (2011) 16.53
SNP detection for massively parallel whole-genome resequencing. Genome Res (2009) 15.96
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell (2008) 14.18
Bis[bis(methoxycarbimido)amine-kappa2N,N']bis(perchlorato-kappaO)copper(II) bis[bis(methoxycarbimido)amine-kappa2N,N']bis(methanol-kappaO)copper(II) bis(perchlorate) methanol disolvate. Acta Crystallogr C (2006) 14.17
Bats are natural reservoirs of SARS-like coronaviruses. Science (2005) 13.44
WEGO: a web tool for plotting GO annotations. Nucleic Acids Res (2006) 13.06
Mapping copy number variation by population-scale genome sequencing. Nature (2011) 12.55
A systematic survey of loss-of-function variants in human protein-coding genes. Science (2012) 12.25
SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science (2005) 12.02
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
Sequencing of 50 human exomes reveals adaptation to high altitude. Science (2010) 11.27
TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acids Res (2006) 8.83
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature (2010) 7.51
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45
Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell (2009) 7.09
Richness of human gut microbiome correlates with metabolic markers. Nature (2013) 6.93
TreeFam: 2008 Update. Nucleic Acids Res (2007) 6.63
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron (2007) 6.60
Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science (2010) 6.04
Nucleosome dynamics define transcriptional enhancers. Nat Genet (2010) 5.94
CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res (2007) 5.88
Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder. Nat Genet (2011) 5.73
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell (2012) 5.62
Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Building the sequence map of the human pan-genome. Nat Biotechnol (2009) 5.53
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants. Nat Genet (2010) 5.44
Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med (2013) 5.38
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. Nat Cell Biol (2002) 5.37
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS. Nature (2010) 5.26
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection. Nat Genet (2010) 5.20
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Complications of colonoscopy in an integrated health care delivery system. Ann Intern Med (2006) 5.10
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J Clin Oncol (2010) 4.94
The Medicago genome provides insight into the evolution of rhizobial symbioses. Nature (2011) 4.94
Resequencing 50 accessions of cultivated and wild rice yields markers for identifying agronomically important genes. Nat Biotechnol (2011) 4.84
An Aboriginal Australian genome reveals separate human dispersals into Asia. Science (2011) 4.84
PPARgamma and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale. Genes Dev (2008) 4.83
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size. Science (2011) 4.76
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency. JAMA (2013) 4.67
A mammalian organelle map by protein correlation profiling. Cell (2006) 4.54
Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study. BMJ (2011) 4.50
Impact of endoscopic surveillance on mortality from Barrett's esophagus-associated esophageal adenocarcinomas. Gastroenterology (2013) 4.43
RePS: a sequence assembler that masks exact repeats identified from the shotgun data. Genome Res (2002) 4.35
Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci U S A (2012) 4.26
The DNA methylome of human peripheral blood mononuclear cells. PLoS Biol (2010) 4.25
Probable limited person-to-person transmission of highly pathogenic avian influenza A (H5N1) virus in China. Lancet (2008) 4.17
Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor. Cancer Cell (2010) 4.16
KaKs_Calculator: calculating Ka and Ks through model selection and model averaging. Genomics Proteomics Bioinformatics (2006) 4.15
Cistrome: an integrative platform for transcriptional regulation studies. Genome Biol (2011) 4.13
Formation of ArF from LPdAr(F): catalytic conversion of aryl triflates to aryl fluorides. Science (2009) 4.13