Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV.

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Published in Blood on December 20, 2012

Authors

Pablo Tebas1, David Stein, Gwendolyn Binder-Scholl, Rithun Mukherjee, Troy Brady, Tessio Rebello, Laurent Humeau, Michael Kalos, Emmanouil Papasavvas, Luis J Montaner, Daniel Schullery, Farida Shaheen, Andrea L Brennan, Zhaohui Zheng, Julio Cotte, Vladimir Slepushkin, Elizabeth Veloso, Adonna Mackley, Wei-Ting Hwang, Faten Aberra, Jenny Zhan, Jean Boyer, Ronald G Collman, Frederic D Bushman, Bruce L Levine, Carl H June

Author Affiliations

1: Department of Medicine and Center for AIDS Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

Associated clinical trials:

Evaluate the Tolerability and Therapeutic Effects of Repeated Doses of Autologous T Cells With VRX496 in HIV | NCT00295477

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