Published in Nucleic Acids Res on January 15, 2013
Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. Br J Pharmacol (2015) 0.96
Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells. Epigenetics (2014) 0.91
Immune mediators regulate CFTR expression through a bifunctional airway-selective enhancer. Mol Cell Biol (2013) 0.85
A genome-wide analysis of open chromatin in human epididymis epithelial cells reveals candidate regulatory elements for genes coordinating epididymal function. Biol Reprod (2013) 0.85
Glucocorticoids Distinctively Modulate the CFTR Channel with Possible Implications in Lung Development and Transition into Extrauterine Life. PLoS One (2015) 0.78
Chromatin Dynamics in the Regulation of CFTR Expression. Genes (Basel) (2015) 0.78
Comparison between the repression potency of siRNA targeting the coding region and the 3'-untranslated region of mRNA. Biomed Res Int (2013) 0.77
CHD6 regulates the topological arrangement of the CFTR locus. Hum Mol Genet (2015) 0.77
High-density nucleosome occupancy map of human chromosome 9p21-22 reveals chromatin organization of the type I interferon gene cluster. J Interferon Cytokine Res (2014) 0.76
Targeted Integration of a Super-Exon into the CFTR Locus Leads to Functional Correction of a Cystic Fibrosis Cell Line Model. PLoS One (2016) 0.75
A comparison of nucleosome organization in Drosophila cell lines. PLoS One (2017) 0.75
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics (2009) 67.17
Identification of the cystic fibrosis gene: chromosome walking and jumping. Science (1989) 21.46
High-resolution mapping and characterization of open chromatin across the genome. Cell (2008) 15.93
Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature (2008) 12.01
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst (1973) 11.26
Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell (2008) 7.80
FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Res (2006) 7.72
Detection of functional DNA motifs via statistical over-representation. Nucleic Acids Res (2004) 6.31
Determinants of nucleosome organization in primary human cells. Nature (2011) 5.50
High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. Genome Res (2010) 4.69
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol (1994) 4.62
Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J Natl Cancer Inst (1977) 4.35
Direct genomic selection. Nat Methods (2005) 3.61
From DNA sequence to transcriptional behaviour: a quantitative approach. Nat Rev Genet (2009) 2.54
A map of nucleosome positions in yeast at base-pair resolution. Nature (2012) 2.30
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression. Genome Res (2012) 1.99
Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics. Genome Res (2012) 1.85
Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA. Genes Dev (2009) 1.82
The effect of micrococcal nuclease digestion on nucleosome positioning data. PLoS One (2010) 1.51
Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene. Nucleic Acids Res (2010) 1.36
Dynamics of nucleosome invasion by DNA binding proteins. J Mol Biol (2011) 1.35
Dynamic nucleosome-depleted regions at androgen receptor enhancers in the absence of ligand in prostate cancer cells. Mol Cell Biol (2011) 1.34
A regulatory element in intron 1 of the cystic fibrosis transmembrane conductance regulator gene. J Biol Chem (1996) 1.31
Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. Proc Natl Acad Sci U S A (2009) 1.29
HNF1alpha is involved in tissue-specific regulation of CFTR gene expression. Biochem J (2004) 1.25
A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. J Cell Mol Med (2009) 1.23
An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells. Nucleic Acids Res (2009) 1.19
CTCF mediates insulator function at the CFTR locus. Biochem J (2007) 1.16
Ductal epithelial cells cultured from human foetal epididymis and vas deferens: relevance to sterility in cystic fibrosis. J Cell Sci (1989) 1.09
Structural constraints in collaborative competition of transcription factors against the nucleosome. J Mol Biol (2011) 1.03
Analysis of DNase-I-hypersensitive sites at the 3' end of the cystic fibrosis transmembrane conductance regulator gene (CFTR). Biochem J (1999) 1.03
Transcriptional networks driving enhancer function in the CFTR gene. Biochem J (2012) 1.00
Negative regulation by nuclear receptors: a plethora of mechanisms. Trends Endocrinol Metab (2010) 1.00
Molecular mechanisms controlling CFTR gene expression in the airway. J Cell Mol Med (2012) 0.97
Analysis of a DNase I hypersensitive site located -20.9 kb upstream of the CFTR gene. Eur J Biochem (1999) 0.97
Estrogen-dependent expression of the cystic fibrosis transmembrane regulator gene in a novel uterine epithelial cell line. J Cell Sci (1994) 0.97
Novel regulatory mechanisms for the CFTR gene. Biochem Soc Trans (2009) 0.94
Transcriptional regulation of CFTR gene expression. Front Biosci (Elite Ed) (2012) 0.88
Nucleosome occupancy reveals regulatory elements of the CFTR promoter. Nucleic Acids Res (2011) 0.85
CFTR expression from a BAC carrying the complete human gene and associated regulatory elements. J Cell Mol Med (2008) 0.83
A genomic code for nucleosome positioning. Nature (2006) 15.38
The DNA-encoded nucleosome organization of a eukaryotic genome. Nature (2008) 11.41
Distinct modes of regulation by chromatin encoded through nucleosome positioning signals. PLoS Comput Biol (2008) 5.71
Rapid spontaneous accessibility of nucleosomal DNA. Nat Struct Mol Biol (2004) 5.00
Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis. J Natl Cancer Inst (2006) 4.39
The myeloma drug lenalidomide promotes the cereblon-dependent destruction of Ikaros proteins. Science (2013) 4.20
Poly(dA:dT) tracts: major determinants of nucleosome organization. Curr Opin Struct Biol (2009) 3.43
High flexibility of DNA on short length scales probed by atomic force microscopy. Nat Nanotechnol (2006) 3.23
H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state. PLoS Biol (2007) 3.18
What controls nucleosome positions? Trends Genet (2009) 3.15
Spontaneous sharp bending of double-stranded DNA. Mol Cell (2004) 3.11
Collaborative competition mechanism for gene activation in vivo. Mol Cell Biol (2003) 3.10
Nucleosomes facilitate their own invasion. Nat Struct Mol Biol (2004) 2.91
From DNA sequence to transcriptional behaviour: a quantitative approach. Nat Rev Genet (2009) 2.54
High nucleosome occupancy is encoded at human regulatory sequences. PLoS One (2010) 2.43
A map of nucleosome positions in yeast at base-pair resolution. Nature (2012) 2.30
Gene expression divergence in yeast is coupled to evolution of DNA-encoded nucleosome organization. Nat Genet (2009) 2.22
Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. Biopolymers (2007) 2.19
Controls of nucleosome positioning in the human genome. PLoS Genet (2012) 2.14
The phenotypic consequences of CFTR mutations. Ann Hum Genet (2003) 2.09
Using DNA mechanics to predict in vitro nucleosome positions and formation energies. Nucleic Acids Res (2009) 1.93
Nucleosome sequence preferences influence in vivo nucleosome organization. Nat Struct Mol Biol (2010) 1.72
Spontaneous access to DNA target sites in folded chromatin fibers. J Mol Biol (2008) 1.69
Improved alignment of nucleosome DNA sequences using a mixture model. Nucleic Acids Res (2005) 1.60
What does physics have to do with cancer? Nat Rev Cancer (2011) 1.59
Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst Rev (2009) 1.52
Identification of Differentially Expressed MicroRNAs in Osteosarcoma. Sarcoma (2011) 1.48
Identification and characterization of a juvenile hormone response element and its binding proteins. J Biol Chem (2007) 1.40
Dynamics of nucleosome invasion by DNA binding proteins. J Mol Biol (2011) 1.35
Preferentially quantized linker DNA lengths in Saccharomyces cerevisiae. PLoS Comput Biol (2008) 1.34
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
Temporal regulation of CFTR expression during ovine lung development: implications for CF gene therapy. Hum Mol Genet (2002) 1.32
Mechanism of transcriptional silencing in yeast. Cell (2005) 1.31
Dynamics and function of compact nucleosome arrays. Nat Struct Mol Biol (2009) 1.30
Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus. Proc Natl Acad Sci U S A (2009) 1.29
Predicting nucleosome positioning using a duration Hidden Markov Model. BMC Bioinformatics (2010) 1.29
Contribution of histone sequence preferences to nucleosome organization: proposed definitions and methodology. Genome Biol (2010) 1.25
HNF1alpha is involved in tissue-specific regulation of CFTR gene expression. Biochem J (2004) 1.25
A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. J Cell Mol Med (2009) 1.23
Epigenetically reprogramming metastatic tumor cells with an embryonic microenvironment. Epigenomics (2009) 1.22
An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells. Nucleic Acids Res (2009) 1.19
p53 binds preferentially to genomic regions with high DNA-encoded nucleosome occupancy. Genome Res (2010) 1.19
CTCF mediates insulator function at the CFTR locus. Biochem J (2007) 1.16
MicroRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene. Biochem J (2011) 1.15
Evaluation of potential regulatory elements identified as DNase I hypersensitive sites in the CFTR gene. Eur J Biochem (2002) 1.14
The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. J Exp Med (2009) 1.12
Folic acid remodels chromatin on Hes1 and Neurog2 promoters during caudal neural tube development. J Biol Chem (2010) 1.09
Identification of microRNAs as potential prognostic markers in ependymoma. PLoS One (2011) 1.09
The CFTR gene and regulation of its expression. Pediatr Pulmonol (2005) 1.07
Mouse model for acute bacterial prostatitis in genetically distinct inbred strains. Urology (2005) 1.06
Chemical map of Schizosaccharomyces pombe reveals species-specific features in nucleosome positioning. Proc Natl Acad Sci U S A (2013) 1.04
Structural constraints in collaborative competition of transcription factors against the nucleosome. J Mol Biol (2011) 1.03
Alternative 5' exons of the CFTR gene show developmental regulation. Hum Mol Genet (2003) 1.00
Transcriptional networks driving enhancer function in the CFTR gene. Biochem J (2012) 1.00
MUC6 mucin expression inhibits tumor cell invasion. Exp Cell Res (2011) 0.99
Naked mole-rat has increased translational fidelity compared with the mouse, as well as a unique 28S ribosomal RNA cleavage. Proc Natl Acad Sci U S A (2013) 0.99
The role of the SEA (sea urchin sperm protein, enterokinase and agrin) module in cleavage of membrane-tethered mucins. FEBS J (2005) 0.98
The commonality of plasticity underlying multipotent tumor cells and embryonic stem cells. J Cell Biochem (2007) 0.97
Molecular mechanisms controlling CFTR gene expression in the airway. J Cell Mol Med (2012) 0.97
Nucleosome switches. Phys Rev Lett (2008) 0.96
Transcriptional profiling of polycythemia vera identifies gene expression patterns both dependent and independent from the action of JAK2V617F. Clin Cancer Res (2010) 0.95
The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo. Elife (2014) 0.95
A T3 allele in the CFTR gene exacerbates exon 9 skipping in vas deferens and epididymal cell lines and is associated with Congenital Bilateral Absence of Vas Deferens (CBAVD). Hum Mutat (2005) 0.95
N-Glycosylation of the MUC1 mucin in epithelial cells and secretions. Glycobiology (2006) 0.95
Novel regulatory mechanisms for the CFTR gene. Biochem Soc Trans (2009) 0.94
The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice. Histochem Cell Biol (2010) 0.93
Mucin variable number tandem repeat polymorphisms and severity of cystic fibrosis lung disease: significant association with MUC5AC. PLoS One (2011) 0.92
Molecular basis of transcriptional silencing in budding yeast. Biochem Cell Biol (2004) 0.92
The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways. PLoS One (2012) 0.91
High-resolution nucleosome mapping of targeted regions using BAC-based enrichment. Nucleic Acids Res (2013) 0.91
A chemical approach to mapping nucleosomes at base pair resolution in yeast. Methods Enzymol (2012) 0.90
Deletion of CFTR translation start site reveals functional isoforms of the protein in CF patients. Cell Physiol Biochem (2009) 0.90
Inheritance of susceptibility to induced Escherichia coli bladder and kidney infections in female C3H/HeJ mice. J Infect Dis (2003) 0.90
Methods for RNA extraction, cDNA preparation and analysis of CFTR transcripts. J Cyst Fibros (2004) 0.89
The contribution of tandem repeat number to the O-glycosylation of mucins. Glycobiology (2002) 0.89
Two-step mechanism for modifier of transcription 1 (Mot1) enzyme-catalyzed displacement of TATA-binding protein (TBP) from DNA. J Biol Chem (2012) 0.89
Stopped-flow fluorescence resonance energy transfer for analysis of nucleosome dynamics. Methods (2007) 0.89
Atypical 5' splice sites cause CFTR exon 9 to be vulnerable to skipping. Am J Hum Genet (2002) 0.88
A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function. Thorax (2011) 0.88
Transcriptional regulation of CFTR gene expression. Front Biosci (Elite Ed) (2012) 0.88
Evaluation of gene targeting by homologous recombination in ovine somatic cells. Mol Reprod Dev (2003) 0.87
Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors. BMC Cancer (2010) 0.86
Epigenetic reprogramming as a key contributor to melanocyte malignant transformation. Epigenetics (2011) 0.86
DNA polymorphisms in potential regulatory elements of the CFTR gene alter transcription factor binding. Hum Genet (2002) 0.86