Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy.

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Published in J Immunother on February 01, 2013

Authors

Richard A Morgan1, Nachimuthu Chinnasamy, Daniel Abate-Daga, Alena Gros, Paul F Robbins, Zhili Zheng, Mark E Dudley, Steven A Feldman, James C Yang, Richard M Sherry, Giao Q Phan, Marybeth S Hughes, Udai S Kammula, Akemi D Miller, Crystal J Hessman, Ashley A Stewart, Nicholas P Restifo, Martha M Quezado, Meghna Alimchandani, Avi Z Rosenberg, Avindra Nath, Tongguang Wang, Bibiana Bielekova, Simone C Wuest, Nirmala Akula, Francis J McMahon, Susanne Wilde, Barbara Mosetter, Dolores J Schendel, Carolyn M Laurencot, Steven A Rosenberg

Author Affiliations

1: Surgery Branch, National Cancer Institute, Bethesda, MD 20892, USA. rmorgan@mail.nih.gov

Associated clinical trials:

GSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Non-Small Cell Lung Cancer | NCT00480025

MAGE-A3/12 Metastatic Cancer Treatment With Anti-MAGE-A3/12 TCR-Gene Engineered Lymphocytes | NCT01273181

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