Published in Gut Microbes on February 04, 2013
Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates. PLoS One (2015) 1.41
Different distribution of Helicobacter pylori EPIYA- cagA motifs and dupA genes in the upper gastrointestinal diseases and correlation with clinical outcomes in iranian patients. Gastroenterol Hepatol Bed Bench (2015) 0.83
Electron microscopic, genetic and protein expression analyses of Helicobacter acinonychis strains from a Bengal tiger. PLoS One (2013) 0.83
Analysis of a single Helicobacter pylori strain over a 10-year period in a primate model. Int J Med Microbiol (2015) 0.80
Dynamic Expansion and Contraction of cagA Copy Number in Helicobacter pylori Impact Development of Gastric Disease. MBio (2017) 0.78
Interactions between pork consumption, CagA status and IL-1B-31 genotypes in gastric cancer. World J Gastroenterol (2014) 0.78
The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori. Dig Dis Sci (2016) 0.76
Impact of structural polymorphism for the Helicobacter pylori CagA oncoprotein on binding to polarity-regulating kinase PAR1b. Sci Rep (2016) 0.76
Host pathogen interactions in Helicobacter pylori related gastric cancer. World J Gastroenterol (2017) 0.75
A role for the tfs3 ICE-encoded type IV secretion system in pro-inflammatory signalling by the Helicobacter pylori Ser/Thr kinase, CtkA. PLoS One (2017) 0.75
Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet (1984) 32.58
Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med (1991) 23.89
Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature (1999) 19.34
Helicobacter pylori infection and the development of gastric cancer. N Engl J Med (2001) 17.13
cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci U S A (1996) 16.69
Hay fever, hygiene, and household size. BMJ (1989) 15.94
Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem (1995) 12.61
Traces of human migrations in Helicobacter pylori populations. Science (2003) 11.92
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci U S A (1993) 11.85
Helicobacter pylori infection and gastric lymphoma. N Engl J Med (1994) 10.26
Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature (2000) 8.96
Cytotoxic activity in broth-culture filtrates of Campylobacter pylori. J Med Microbiol (1988) 8.69
Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science (2000) 7.99
Helicobacter pylori virulence and genetic geography. Science (1999) 7.64
An African origin for the intimate association between humans and Helicobacter pylori. Nature (2007) 6.91
Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci U S A (1999) 6.34
Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med (1989) 5.78
What are the consequences of the disappearing human microbiota? Nat Rev Microbiol (2009) 5.62
SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science (2001) 5.49
Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA. Science (2003) 5.23
Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci U S A (2000) 5.07
Helicobacter pylori persistence: biology and disease. J Clin Invest (2004) 4.75
Relationship between Helicobacter pylori iceA, cagA, and vacA status and clinical outcome: studies in four different countries. J Clin Microbiol (1999) 4.13
Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology (1998) 4.11
Helicobacter pylori colonization is inversely associated with childhood asthma. J Infect Dis (2008) 3.95
Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer (2004) 3.88
Helicobacter pylori in health and disease. Gastroenterology (2009) 3.84
The disease spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer. Annu Rev Microbiol (2000) 3.79
A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer. Gastroenterology (2007) 3.54
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc Natl Acad Sci U S A (2002) 3.50
Inverse associations of Helicobacter pylori with asthma and allergy. Arch Intern Med (2007) 3.48
Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo. J Biol Chem (2002) 3.47
Differences in genotypes of Helicobacter pylori from different human populations. J Bacteriol (2000) 3.39
c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol Microbiol (2002) 3.20
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci U S A (2008) 3.17
The peopling of the Pacific from a bacterial perspective. Science (2009) 3.14
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan. J Clin Microbiol (1997) 2.89
Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh. Proc Natl Acad Sci U S A (2004) 2.83
Infection with Helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum (1994) 2.68
Does Helicobacter pylori protect against asthma and allergy? Gut (2008) 2.67
Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cells. J Immunol (1998) 2.65
Clinical relevance of Helicobacter pylori cagA and vacA gene polymorphisms. Gastroenterology (2008) 2.63
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature (2007) 2.48
Relationship between the cagA 3' repeat region of Helicobacter pylori, gastric histology, and susceptibility to low pH. Gastroenterology (1999) 2.44
Relationship of vacA genotypes of Helicobacter pylori to cagA status, cytotoxin production, and clinical outcome. Helicobacter (1998) 2.39
Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol (1995) 2.37
Helicobacter pylori infection and the risk of development of esophageal adenocarcinoma. J Infect Dis (2005) 2.28
Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase. J Biol Chem (2002) 2.23
Tolerance rather than immunity protects from Helicobacter pylori-induced gastric preneoplasia. Gastroenterology (2010) 2.17
Asthma is inversely associated with Helicobacter pylori status in an urban population. PLoS One (2008) 2.04
Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation. J Biol Chem (2004) 2.01
Molecular epidemiology of Helicobacter pylori: separation of H. pylori from East Asian and non-Asian countries. Epidemiol Infect (2000) 1.97
Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammation. Cell Host Microbe (2009) 1.96
Helicobacter pylori exploits host membrane phosphatidylserine for delivery, localization, and pathophysiological action of the CagA oncoprotein. Cell Host Microbe (2010) 1.93
Helicobacter pylori gastritis in children is associated with a regulatory T-cell response. Gastroenterology (2007) 1.91
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells. Proc Natl Acad Sci U S A (2005) 1.89
Association between Helicobacter pylori infection and inflammatory bowel disease: a meta-analysis and systematic review of the literature. Inflamm Bowel Dis (2010) 1.86
Association between gastric Helicobacter pylori colonization and glycated hemoglobin levels. J Infect Dis (2012) 1.84
Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin. J Cell Biol (1996) 1.82
Helicobacter pylori cagA and vacA genotypes as predictors of progression of gastric preneoplastic lesions: a long-term follow-up in a high-risk area in Spain. Am J Gastroenterol (2011) 1.79
Association between diversity in the Src homology 2 domain--containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer. J Infect Dis (2004) 1.78
Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA. Gastroenterology (2006) 1.77
The association between Barrett's esophagus and Helicobacter pylori infection: a meta-analysis. Helicobacter (2012) 1.74
Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche. PLoS Pathog (2009) 1.73
Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA. Cell Host Microbe (2012) 1.72
Distinct diversity of vacA, cagA, and cagE genes of Helicobacter pylori associated with peptic ulcer in Japan. J Clin Microbiol (2005) 1.72
The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer. Nature (2001) 1.71
Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering. Gastroenterology (2007) 1.70
Helicobacter pylori-induced peptic ulcer disease is associated with inadequate regulatory T cell responses. Gut (2008) 1.69
Frontal and stealth attack strategies in microbial pathogenesis. Nature (2004) 1.69
DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection. J Clin Invest (2012) 1.68
Apical junctional complexes and cell polarity. Kidney Int (2007) 1.64
Human cancer cell lines: Experimental models for cancer cells in situ? For cancer stem cells? Biochim Biophys Acta (2009) 1.62
The versatility of Helicobacter pylori CagA effector protein functions: The master key hypothesis. Helicobacter (2010) 1.59
Phosphorylation of Helicobacter pylori CagA by c-Abl leads to cell motility. Oncogene (2006) 1.59
Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis. Cancer Sci (2005) 1.59
Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surface. PLoS Pathog (2011) 1.57
Helicobacter pylori infection and the risk of Barrett's oesophagus: a community-based study. Gut (2007) 1.57
Murine splenocytes induce severe gastritis and delayed-type hypersensitivity and suppress bacterial colonization in Helicobacter pylori-infected SCID mice. Infect Immun (1999) 1.56
Helicobacter pylori and gastric carcinogenesis. J Gastroenterol (2009) 1.54
c-Src and c-Abl kinases control hierarchic phosphorylation and function of the CagA effector protein in Western and East Asian Helicobacter pylori strains. J Clin Invest (2012) 1.53
CagA-positive strains of Helicobacter pylori may protect against Barrett's esophagus. Am J Gastroenterol (2000) 1.53
Determinants of non-toxicity in the gastric pathogen Helicobacter pylori. J Biol Chem (2003) 1.51
Relationship between Helicobacter pylori infection and esophageal neoplasia: a meta-analysis. Clin Gastroenterol Hepatol (2007) 1.49
Helicobacter pylori from Peruvian amerindians: traces of human migrations in strains from remote Amazon, and genome sequence of an Amerind strain. PLoS One (2010) 1.48
A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation. J Bacteriol (2001) 1.47
Helicobacter pylori's unconventional role in health and disease. PLoS Pathog (2009) 1.47
The Helicobacter pylori vacA s1, m1 genotype and cagA is associated with gastric carcinoma in Germany. Int J Cancer (2000) 1.46
Infection with Helicobacter pylori is associated with protection against tuberculosis. PLoS One (2010) 1.45
Functional association between the Helicobacter pylori virulence factors VacA and CagA. J Med Microbiol (2008) 1.44
Evidence that cagA(+) Helicobacter pylori strains are disappearing more rapidly than cagA(-) strains. Gut (2002) 1.43
Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. J Biol Chem (2002) 1.41
The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin. BMC Gastroenterol (2011) 1.40
Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells. PLoS Pathog (2009) 1.40
The inflammatory and immune response to Helicobacter pylori infection. Best Pract Res Clin Gastroenterol (2007) 1.35
Serum antibodies against Helicobacter pylori proteins VacA and CagA are associated with increased risk for gastric adenocarcinoma. Dig Dis Sci (1997) 1.34
Natural diversity in the N terminus of the mature vacuolating cytotoxin of Helicobacter pylori determines cytotoxin activity. J Bacteriol (2000) 1.32
Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates. Nat Struct Mol Biol (2009) 1.28
Polymorphism in the CagA EPIYA motif impacts development of gastric cancer. J Clin Microbiol (2009) 1.27
The complete genome sequence of Helicobacter pylori strain G27. J Bacteriol (2008) 2.05
Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression. Infect Immun (2003) 2.02
This is not your mother's repressor: the complex role of fur in pathogenesis. Infect Immun (2009) 1.71
Iron and pH homeostasis intersect at the level of Fur regulation in the gastric pathogen Helicobacter pylori. Infect Immun (2006) 1.48
Phosphorylation-independent effects of CagA during interaction between Helicobacter pylori and T84 polarized monolayers. J Infect Dis (2004) 1.32
Polymorphism in the CagA EPIYA motif impacts development of gastric cancer. J Clin Microbiol (2009) 1.27
Inducible nitric oxide synthetase genotype and Helicobacter pylori infection affect gastric cancer risk. World J Gastroenterol (2012) 1.22
Expanding the Helicobacter pylori genetic toolbox: modification of an endogenous plasmid for use as a transcriptional reporter and complementation vector. Appl Environ Microbiol (2007) 1.18
Epidemiological link between gastric disease and polymorphisms in VacA and CagA. J Clin Microbiol (2009) 1.13
ToxR interferes with CRP-dependent transcriptional activation of ompT in Vibrio cholerae. Mol Microbiol (2002) 1.07
Sodium chloride affects Helicobacter pylori growth and gene expression. J Bacteriol (2008) 1.05
Frequency of antibiotic resistance in Helicobacter pylori strains isolated from the northern population of Iran. J Microbiol (2011) 1.04
A single nucleotide change affects fur-dependent regulation of sodB in H. pylori. PLoS One (2009) 1.04
Profiling of microdissected gastric epithelial cells reveals a cell type-specific response to Helicobacter pylori infection. Gastroenterology (2004) 1.03
Polymorphism in the interleukin-17A promoter contributes to gastric cancer. World J Gastroenterol (2013) 1.02
Polymorphisms in the intermediate region of VacA impact Helicobacter pylori-induced disease development. J Clin Microbiol (2010) 1.02
Change is good: variations in common biological mechanisms in the epsilonproteobacterial genera Campylobacter and Helicobacter. Microbiol Mol Biol Rev (2011) 1.01
A Tale of Two Toxins: Helicobacter Pylori CagA and VacA Modulate Host Pathways that Impact Disease. Front Microbiol (2010) 1.00
Diet synergistically affects helicobacter pylori-induced gastric carcinogenesis in nonhuman primates. Gastroenterology (2009) 1.00
Helicobacter pylori homB, but not cagA, is associated with gastric cancer in Iran. J Clin Microbiol (2011) 0.99
Fur activates expression of the 2-oxoglutarate oxidoreductase genes (oorDABC) in Helicobacter pylori. J Bacteriol (2012) 0.97
Phylogeographic origin of Helicobacter pylori determines host-adaptive responses upon coculture with gastric epithelial cells. Infect Immun (2013) 0.95
Helicobacter pylori apo-Fur regulation appears unconserved across species. J Microbiol (2010) 0.94
Cytotoxic necrotizing factor 1 and hemolysin from uropathogenic Escherichia coli elicit different host responses in the murine bladder. Infect Immun (2012) 0.93
Molecular characterization of a catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus strain collected from a patient with cutaneous abscess. J Clin Microbiol (2013) 0.93
Antibiotic treatment decreases microbial burden associated with pseudomyxoma peritonei and affects β-catenin distribution. Clin Cancer Res (2013) 0.93
Detailed analysis of Helicobacter pylori Fur-regulated promoters reveals a Fur box core sequence and novel Fur-regulated genes. Mol Microbiol (2012) 0.92
Who's Winning the War? Molecular Mechanisms of Antibiotic Resistance in Helicobacter pylori. Curr Drug ther (2008) 0.92
Helicobacter pylori-induced histone modification, associated gene expression in gastric epithelial cells, and its implication in pathogenesis. PLoS One (2010) 0.91
Detailed in vivo analysis of the role of Helicobacter pylori Fur in colonization and disease. Infect Immun (2010) 0.91
Dietary choice affects Shiga toxin-producing Escherichia coli (STEC) O157:H7 colonization and disease. Proc Natl Acad Sci U S A (2013) 0.91
A core microbiome associated with the peritoneal tumors of pseudomyxoma peritonei. Orphanet J Rare Dis (2013) 0.90
Mutagenesis of conserved amino acids of Helicobacter pylori fur reveals residues important for function. J Bacteriol (2010) 0.89
The Helicobacter pylori Ferric Uptake Regulator (Fur) is essential for growth under sodium chloride stress. J Microbiol (2011) 0.88
Spatiotemporal analysis of acid adaptation-mediated Vibrio cholerae hyperinfectivity. Infect Immun (2004) 0.88
The oligo-acyl lysyl antimicrobial peptide C₁₂K-2β₁₂ exhibits a dual mechanism of action and demonstrates strong in vivo efficacy against Helicobacter pylori. Antimicrob Agents Chemother (2011) 0.87
In vitro characterization of the anti-bacterial activity of SQ109 against Helicobacter pylori. PLoS One (2013) 0.87
Identification and characterization of novel Helicobacter pylori apo-fur-regulated target genes. J Bacteriol (2013) 0.86
Balancing the double-edged sword: metal ion homeostasis and the ulcer bug. Curr Med Chem (2007) 0.85
Enterobacterial common antigen mutants of Salmonella enterica serovar Typhimurium establish a persistent infection and provide protection against subsequent lethal challenge. Infect Immun (2011) 0.83
Nontraditional therapies to treat Helicobacter pylori infection. J Microbiol (2014) 0.82
Genetic analysis of Helicobacter pylori clinical isolates suggests resistance to metronidazole can occur without the loss of functional rdxA. J Antibiot (Tokyo) (2009) 0.82
In vitro antibacterial activity of acyl-lysyl oligomers against Helicobacter pylori. Antimicrob Agents Chemother (2009) 0.81
The ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach. Future Microbiol (2013) 0.81
The geographic origin of Helicobacter pylori influences the association of the homB gene with gastric cancer. J Clin Microbiol (2012) 0.80
Dynamic HypA zinc site is essential for acid viability and proper urease maturation in Helicobacter pylori. Metallomics (2015) 0.79
Random and site-specific mutagenesis of the Helicobacter pylori ferric uptake regulator provides insight into Fur structure-function relationships. Mol Microbiol (2013) 0.79
Successful culture techniques for Helicobacter species: general culture techniques for Helicobacter pylori. Methods Mol Biol (2012) 0.78
Microarray analysis of Shigella flexneri-infected epithelial cells identifies host factors important for apoptosis inhibition. BMC Genomics (2010) 0.78
Complementation system for Helicobacter pylori. J Microbiol (2011) 0.76
Successful culture techniques for Helicobacter species: verification of Helicobacter identity using 16S rRNA gene sequence analysis. Methods Mol Biol (2012) 0.76
Response to Abadi and Kusters, World J Gastroenterol 19:429-430. World J Gastroenterol (2013) 0.75
Correction: Helicobacter pylori bab Paralog Distribution and Association with cagA, vacA, and homA/B Genotypes in American and South Korean Clinical Isolates. PLoS One (2017) 0.75
Research advances in the study of Campylobacter, Helicobacter, and related organisms. Front Cell Infect Microbiol (2012) 0.75
Molecular mechanisms of gastric cancer initiation and progression by Helicobacter pylori. Curr Opin Infect Dis (2016) 0.75
Successful culture techniques for Helicobacter species: establishing H. pylori cultures from infected rodents. Methods Mol Biol (2012) 0.75