Chimeric antigen receptor (CAR)-specific monoclonal antibody to detect CD19-specific T cells in clinical trials.

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Published in PLoS One on March 01, 2013

Authors

Bipulendu Jena1, Sourindra Maiti, Helen Huls, Harjeet Singh, Dean A Lee, Richard E Champlin, Laurence J N Cooper

Author Affiliations

1: Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

Associated clinical trials:

Genetically Engineered Lymphocyte Therapy in Treating Patients With B-Cell Leukemia or Lymphoma That is Resistant or Refractory to Chemotherapy | NCT01029366

CD19-specific T Cell Infusion in Patients With B-Lineage Lymphoid Malignancies | NCT00968760

Infusion of Allogeneic CD19-Specific T Cells From Peripheral Blood | NCT01497184

Infusion of Allogeneic Umbilical Cord Blood-Derived CD19-Specific T Cells | NCT01362452

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