Temsirolimus combined with sorafenib in hepatocellular carcinoma: a phase I dose-finding trial with pharmacokinetic and biomarker correlates.

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Published in Ann Oncol on March 21, 2013

Authors

R K Kelley1, H S Nimeiri, P N Munster, M T Vergo, Y Huang, C-M Li, J Hwang, M F Mulcahy, B M Yeh, P Kuhn, M S Luttgen, J A Grabowsky, L Stucky-Marshall, W M Korn, A H Ko, E K Bergsland, A B Benson, A P Venook

Author Affiliations

1: Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco, CA 94143, USA. katie.kelley@ucsf.edu

Associated clinical trials:

Global Study Looking at the Combination of RAD001 Plus Best Supportive Care (BSC) and Placebo Plus BSC to Treat Patients With Advanced Hepatocellular Carcinoma. (EVOLVE-1) | NCT01035229

Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma | NCT00355862

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