Published in J Orthop Res on April 01, 2013
Translation of an engineered nanofibrous disc-like angle-ply structure for intervertebral disc replacement in a small animal model. Acta Biomater (2014) 0.85
Population average T2 MRI maps reveal quantitative regional transformations in the degenerating rabbit intervertebral disc that vary by lumbar level. J Orthop Res (2014) 0.82
Effects of neonatal enzyme replacement therapy and simvastatin treatment on cervical spine disease in mucopolysaccharidosis I dogs. J Bone Miner Res (2014) 0.78
Disc cell therapies: critical issues. Eur Spine J (2014) 0.76
A large animal model that recapitulates the spectrum of human intervertebral disc degeneration. Osteoarthritis Cartilage (2016) 0.75
Lumbar intervertebral disc puncture under C-arm fluoroscopy: a new rat model of lumbar intervertebral disc degeneration. Exp Anim (2014) 0.75
In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification. PLoS One (2016) 0.75
Hydrogel-based nanocomposites and mesenchymal stem cells: a promising synergistic strategy for neurodegenerative disorders therapy. ScientificWorldJournal (2013) 0.75
Needle puncture in rabbit functional spinal units alters rotational biomechanics. J Spinal Disord Tech (2015) 0.75
Age-related reduction in the expression of FOXO transcription factors and correlations with intervertebral disc degeneration. J Orthop Res (2017) 0.75
A novel rat tail discitis model using bioluminescent Staphylococcus aureus. J Orthop Res (2016) 0.75
The effect of annular repair on the failure strength of the porcine lumbar disc after needle puncture and punch injury. Eur Spine J (2015) 0.75
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat Genet (2006) 3.79
The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature (2005) 3.78
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Genetic analysis of the roles of BMP2, BMP4, and BMP7 in limb patterning and skeletogenesis. PLoS Genet (2006) 3.27
Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol (2009) 3.02
Epidermal stem cells arise from the hair follicle after wounding. FASEB J (2007) 2.81
MicroRNA expression is required for pancreatic islet cell genesis in the mouse. Diabetes (2007) 2.80
Essential role for Dicer during skeletal muscle development. Dev Biol (2007) 2.76
Podocyte-specific deletion of dicer alters cytoskeletal dynamics and causes glomerular disease. J Am Soc Nephrol (2008) 2.69
The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol (2008) 2.61
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. J Neurosci (2008) 2.50
Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci U S A (2009) 2.33
Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration. Proc Natl Acad Sci U S A (2008) 2.32
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons. Nat Neurosci (2012) 2.28
Effect of fiber distribution and realignment on the nonlinear and inhomogeneous mechanical properties of human supraspinatus tendon under longitudinal tensile loading. J Orthop Res (2009) 2.11
Effect of fiber orientation and strain rate on the nonlinear uniaxial tensile material properties of tendon. J Biomech Eng (2003) 2.11
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
Assessment of human disc degeneration and proteoglycan content using T1rho-weighted magnetic resonance imaging. Spine (Phila Pa 1976) (2006) 2.01
LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. FASEB J (2009) 1.99
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Quantifying the contributions of structure to annulus fibrosus mechanical function using a nonlinear, anisotropic, hyperelastic model. J Orthop Res (2007) 1.94
Tmem16A encodes the Ca2+-activated Cl- channel in mouse submandibular salivary gland acinar cells. J Biol Chem (2010) 1.93
Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: implications for disk degeneration and chordoma formation. Dev Dyn (2008) 1.91
Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. J Orthop Res (2007) 1.90
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration. Tissue Eng Part B Rev (2009) 1.88
Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus. Nat Mater (2009) 1.83
Comparison of animals used in disc research to human lumbar disc geometry. Spine (Phila Pa 1976) (2007) 1.72
Degeneration and regeneration of the intervertebral disc: lessons from development. Dis Model Mech (2010) 1.69
Quantification of cartilage biomechanical and biochemical properties via T1rho magnetic resonance imaging. Magn Reson Med (2005) 1.61
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Comparison of animal discs used in disc research to human lumbar disc: axial compression mechanics and glycosaminoglycan content. Spine (Phila Pa 1976) (2008) 1.59
In vivo quantification of human lumbar disc degeneration using T(1rho)-weighted magnetic resonance imaging. Eur Spine J (2006) 1.58
Residual microRNA expression dictates the extent of inner ear development in conditional Dicer knockout mice. Dev Biol (2009) 1.55
Dicer1 is required for differentiation of the mouse male germline. Biol Reprod (2008) 1.52
Cell lineage analysis demonstrates an endodermal origin of the distal urethra and perineum. Dev Biol (2008) 1.51
Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons. Neuron (2012) 1.50
Effects of degeneration on the biphasic material properties of human nucleus pulposus in confined compression. Spine (Phila Pa 1976) (2005) 1.50
Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. Mol Cell Biol (2002) 1.49
A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning. Dev Cell (2003) 1.48
The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells. Science (2004) 1.40
Low-intensity vibrations partially maintain intervertebral disc mechanics and spinal muscle area during deconditioning. Spine J (2013) 1.40
Material properties in unconfined compression of human nucleus pulposus, injectable hyaluronic acid-based hydrogels and tissue engineering scaffolds. Eur Spine J (2007) 1.37
Sertoli cell Dicer is essential for spermatogenesis in mice. Dev Biol (2008) 1.37
Tensile properties and fiber alignment of human supraspinatus tendon in the transverse direction demonstrate inhomogeneity, nonlinearity, and regional isotropy. J Biomech (2009) 1.36
Degeneration affects the fiber reorientation of human annulus fibrosus under tensile load. J Biomech (2005) 1.34
Ano1 as a regulator of proliferation. Am J Physiol Gastrointest Liver Physiol (2011) 1.32
Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell (2007) 1.31
Genetic analyses reveal a requirement for Dicer1 in the mouse urogenital tract. Mamm Genome (2009) 1.31
Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn (2008) 1.30
Functional genomic analysis of the ADP-ribosylation factor family of GTPases: phylogeny among diverse eukaryotes and function in C. elegans. FASEB J (2004) 1.28
Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development (2005) 1.27
Interpretation of whole body dual energy X-ray absorptiometry measures in children: comparison with peripheral quantitative computed tomography. Bone (2004) 1.26
A biphasic and transversely isotropic mechanical model for tendon: application to mouse tail fascicles in uniaxial tension. J Biomech (2004) 1.26
Human internal disc strains in axial compression measured noninvasively using magnetic resonance imaging. Spine (Phila Pa 1976) (2007) 1.23
Multiphasic and tissue-specific roles of sonic hedgehog in cloacal septation and external genitalia development. Development (2009) 1.23
Theoretical and uniaxial experimental evaluation of human annulus fibrosus degeneration. J Biomech Eng (2009) 1.22
BMP4 is dispensable for skeletogenesis and fracture-healing in the limb. J Bone Joint Surg Am (2008) 1.20
Engineered disc-like angle-ply structures for intervertebral disc replacement. Spine (Phila Pa 1976) (2010) 1.19
Fabrication and modeling of dynamic multipolymer nanofibrous scaffolds. J Biomech Eng (2009) 1.19
ISSLS prize winner: integrating theoretical and experimental methods for functional tissue engineering of the annulus fibrosus. Spine (Phila Pa 1976) (2008) 1.19
Noninvasive quantification of human nucleus pulposus pressure with use of T1rho-weighted magnetic resonance imaging. J Bone Joint Surg Am (2008) 1.16
Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs. Proc Natl Acad Sci U S A (2011) 1.15
Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand. Development (2004) 1.13
Intervertebral disc mechanics are restored following cyclic loading and unloaded recovery. Ann Biomed Eng (2004) 1.13
Characterization of a novel ectodermal signaling center regulating Tbx2 and Shh in the vertebrate limb. Dev Biol (2006) 1.13
Homologous structure-function relationships between native fibrocartilage and tissue engineered from MSC-seeded nanofibrous scaffolds. Biomaterials (2010) 1.12
Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol (2005) 1.11
Nucleus pulposus glycosaminoglycan content is correlated with axial mechanics in rat lumbar motion segments. J Orthop Res (2006) 1.10
Mechanical design criteria for intervertebral disc tissue engineering. J Biomech (2010) 1.09
Mechanical differences between lumbar and tail discs in the mouse. J Orthop Res (2005) 1.08
Human intervertebral disc internal strain in compression: the effect of disc region, loading position, and degeneration. J Orthop Res (2010) 1.07
Characterizing the mechanical contribution of fiber angular distribution in connective tissue: comparison of two modeling approaches. Biomech Model Mechanobiol (2010) 1.06
Human annulus fibrosus material properties from biaxial testing and constitutive modeling are altered with degeneration. Biomech Model Mechanobiol (2011) 1.06
Evaluation of intervertebral disc cartilaginous endplate structure using magnetic resonance imaging. Eur Spine J (2013) 1.06
The role of fiber-matrix interactions in a nonlinear fiber-reinforced strain energy model of tendon. J Biomech Eng (2005) 1.04
Trans-endplate nucleotomy increases deformation and creep response in axial loading. Ann Biomed Eng (2006) 1.04
Expression patterns of the Tmem16 gene family during cephalic development in the mouse. Gene Expr Patterns (2008) 1.04
Biaxial tensile testing and constitutive modeling of human supraspinatus tendon. J Biomech Eng (2012) 1.03
In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev Biol (2009) 1.01
T1ρ magnetic resonance imaging and discography pressure as novel biomarkers for disc degeneration and low back pain. Spine (Phila Pa 1976) (2011) 1.01
Elastin content correlates with human disc degeneration in the anulus fibrosus and nucleus pulposus. Spine (Phila Pa 1976) (2007) 1.01
Fiber stretch and reorientation modulates mesenchymal stem cell morphology and fibrous gene expression on oriented nanofibrous microenvironments. Ann Biomed Eng (2011) 1.00
Analysis of the regulation of lin-41 during chick and mouse limb development. Dev Dyn (2005) 1.00
Dynamic culture enhances stem cell infiltration and modulates extracellular matrix production on aligned electrospun nanofibrous scaffolds. Acta Biomater (2010) 0.98
An in vivo model of reduced nucleus pulposus glycosaminoglycan content in the rat lumbar intervertebral disc. Spine (Phila Pa 1976) (2008) 0.97
Nucleus pulposus cells synthesize a functional extracellular matrix and respond to inflammatory cytokine challenge following long-term agarose culture. Eur Cell Mater (2011) 0.97
MicroRNAs in mammalian development and tumorigenesis. Birth Defects Res C Embryo Today (2006) 0.97
Rat disc torsional mechanics: effect of lumbar and caudal levels and axial compression load. Spine J (2008) 0.97
IL-1ra delivered from poly(lactic-co-glycolic acid) microspheres attenuates IL-1β-mediated degradation of nucleus pulposus in vitro. Arthritis Res Ther (2012) 0.96
Electrical slow waves in the mouse oviduct are dependent upon a calcium activated chloride conductance encoded by Tmem16a. Biol Reprod (2012) 0.95
Extra-fibrillar matrix mechanics of annulus fibrosus in tension and compression. Biomech Model Mechanobiol (2011) 0.94