Multicenter phase II study of neoadjuvant lapatinib and trastuzumab with hormonal therapy and without chemotherapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer: TBCRC 006.

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Published in J Clin Oncol on April 08, 2013

Authors

Mothaffar F Rimawi1, Ingrid A Mayer, Andres Forero, Rita Nanda, Matthew P Goetz, Angel A Rodriguez, Anne C Pavlick, Tao Wang, Susan G Hilsenbeck, Carolina Gutierrez, Rachel Schiff, C Kent Osborne, Jenny C Chang

Author Affiliations

1: Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. rimawi@bcm.edu

Associated clinical trials:

Lapatinib and Trastuzumab With or Without Endocrine Therapy | NCT00548184

PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast Cancer (PAMELA) | NCT01973660

Study to Compare Neoadjuvant Combination of Trastuzumab and Pertuzumab With Concurrent Taxane Chemotherapy or Endocrine Therapy and Quality of Life Assessment Under Adjuvant Therapy in Operable HER2+/HR+ Breast Cancer Patients (TP-II) | NCT03272477

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