Published in PLoS Genet on April 04, 2013
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The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease. Dis Model Mech (2015) 0.79
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DJ-1 decreases Bax expression through repressing p53 transcriptional activity. J Biol Chem (2007) 1.59
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Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene (2005) 1.46
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p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J Neurochem (2006) 1.41
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc Natl Acad Sci U S A (2010) 1.38
Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons. Mol Neurodegener (2008) 1.37
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Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1. J Biol Chem (2009) 1.24
DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum Mol Genet (2012) 1.22
In vivo p53 function is indispensable for DNA damage-induced apoptotic signaling in Drosophila. FEBS Lett (2003) 1.21
Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation. Hum Mol Genet (2008) 1.05
The characterization of the invasion phenotype of uveal melanoma tumour cells shows the presence of MUC18 and HMG-1 metastasis markers and leads to the identification of DJ-1 as a potential serum biomarker. Int J Cancer (2006) 1.05
Daxx is required for stress-induced cell death and JNK activation. Cell Death Differ (2005) 1.04
DJ-1 modulates UV-induced oxidative stress signaling through the suppression of MEKK1 and cell death. Cell Death Differ (2008) 0.90
Oxidative stress and Parkinson's disease. Handb Clin Neurol (2007) 0.89
PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity. Mol Cells (2012) 0.87
Catalase, but not MnSOD, inhibits glucose deprivation-activated ASK1-MEK-MAPK signal transduction pathway and prevents relocalization of Daxx: hydrogen peroxide as a major second messenger of metabolic oxidative stress. J Cell Biochem (2003) 0.86
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Expression of a dominant negative form of Daxx in vivo rescues motoneurons from Fas (CD95)-induced cell death. J Neurobiol (2005) 0.84
dXNP/DATRX increases apoptosis via the JNK and dFOXO pathway in Drosophila neurons. Biochem Biophys Res Commun (2009) 0.83
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PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. Biochem Biophys Res Commun (2008) 3.06
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Host cell autophagy activated by antibiotics is required for their effective antimycobacterial drug action. Cell Host Microbe (2012) 1.99
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The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. Biochem Biophys Res Commun (2008) 1.84
Mechanisms for regulation of Hsp70 function by Hsp40. Cell Stress Chaperones (2003) 1.84
Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila. Biochem Biophys Res Commun (2007) 1.78
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Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J Biol Chem (2001) 1.56
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc Natl Acad Sci U S A (2005) 1.48
Exchangeable chaperone modules contribute to specification of type I and type II Hsp40 cellular function. Mol Biol Cell (2003) 1.48
Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene (2005) 1.46
Akt: versatile mediator of cell survival and beyond. J Biochem Mol Biol (2002) 1.43
New species of Bordetella, Bordetella ansorpii sp. nov., isolated from the purulent exudate of an epidermal cyst. J Clin Microbiol (2005) 1.41
Caspar, a suppressor of antibacterial immunity in Drosophila. Proc Natl Acad Sci U S A (2006) 1.36
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Use of viscogens, dNTPalphaS, and rhodium(III) as probes in stopped-flow experiments to obtain new evidence for the mechanism of catalysis by DNA polymerase beta. Biochemistry (2005) 1.32
Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes (2009) 1.31
Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation. Cell Metab (2009) 1.29
cAMP signalling in mushroom bodies modulates temperature preference behaviour in Drosophila. Nature (2008) 1.29
Cdk2-dependent phosphorylation of the NF-Y transcription factor and its involvement in the p53-p21 signaling pathway. J Biol Chem (2003) 1.23
In vivo p53 function is indispensable for DNA damage-induced apoptotic signaling in Drosophila. FEBS Lett (2003) 1.21
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Mitochondrial dysfunction and Parkinson's disease genes: insights from Drosophila. Dis Model Mech (2009) 1.18
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FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly. J Biol Chem (2007) 1.17
Discrete functions of TRAF1 and TRAF2 in Drosophila melanogaster mediated by c-Jun N-terminal kinase and NF-kappaB-dependent signaling pathways. Mol Cell Biol (2003) 1.17
CRIF1 is essential for the synthesis and insertion of oxidative phosphorylation polypeptides in the mammalian mitochondrial membrane. Cell Metab (2012) 1.17
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Complete genome sequence of Enterobacter aerogenes KCTC 2190. J Bacteriol (2012) 1.08
blistery encodes Drosophila tensin protein and interacts with integrin and the JNK signaling pathway during wing development. Development (2003) 1.08
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Newly identified tumor-associated role of human Sharpin. Mol Cell Biochem (2010) 1.07
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
Photosynthetic Characteristics of Resistance and Susceptible Lines to High Temperature Injury in Panax ginseng Meyer. J Ginseng Res (2012) 1.05
MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development. Mol Cell Biol (2004) 1.04
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Development of a prognostic model for six-month mortality in older adults with declining health. J Pain Symptom Manage (2011) 1.02
Complete genome sequence of Klebsiella oxytoca KCTC 1686, used in production of 2,3-butanediol. J Bacteriol (2012) 1.02
Ordered arrays of ZnO nanorods grown on periodically polarity-inverted surfaces. Nano Lett (2008) 1.02
Regulation of FOXO1 by TAK1-Nemo-like kinase pathway. J Biol Chem (2010) 1.02
SMARCAL1 deficiency predisposes to non-Hodgkin lymphoma and hypersensitivity to genotoxic agents in vivo. Am J Med Genet A (2012) 1.01
Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development. EMBO J (2006) 1.01
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor. J Med Chem (2014) 0.99
Microglial Toll-like receptor 2 contributes to kainic acid-induced glial activation and hippocampal neuronal cell death. J Biol Chem (2010) 0.99
Assessment of exposure to heavy metals and health risks among residents near abandoned metal mines in Goseong, Korea. Environ Pollut (2013) 0.99
Dopamine signalling in mushroom bodies regulates temperature-preference behaviour in Drosophila. PLoS Genet (2011) 0.98
Complete Genome Sequence of Raoultella ornithinolytica Strain B6, a 2,3-Butanediol-Producing Bacterium Isolated from Oil-Contaminated Soil. Genome Announc (2013) 0.97
DNA damage-induced RORα is crucial for p53 stabilization and increased apoptosis. Mol Cell (2011) 0.97
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Complete genome sequence of the 2,3-butanediol-producing Klebsiella pneumoniae strain KCTC 2242. J Bacteriol (2012) 0.96
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors. J Med Chem (2013) 0.96
Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function. Mol Cells (2009) 0.96
UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Dev Biol (2011) 0.95
Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice. PLoS Genet (2013) 0.95
Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J Biol Chem (2013) 0.94
Drosophila Porin/VDAC affects mitochondrial morphology. PLoS One (2010) 0.94
Toll-like receptors: sensor molecules for detecting damage to the nervous system. Curr Protein Pept Sci (2013) 0.93
Enhanced 2,3-butanediol production in recombinant Klebsiella pneumoniae via overexpression of synthesis-related genes. J Microbiol Biotechnol (2012) 0.91
LKB1 induces apical trafficking of Silnoon, a monocarboxylate transporter, in Drosophila melanogaster. J Cell Biol (2008) 0.91
Streptococcus suis meningitis with bilateral sensorineural hearing loss. Korean J Lab Med (2011) 0.91
Silent information regulator 2 (Sir2) and Forkhead box O (FOXO) complement mitochondrial dysfunction and dopaminergic neuron loss in Drosophila PTEN-induced kinase 1 (PINK1) null mutant. J Biol Chem (2012) 0.91
Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis. J Med Chem (2013) 0.91
AMP kinase activation mitigates dopaminergic dysfunction and mitochondrial abnormalities in Drosophila models of Parkinson's disease. J Neurosci (2012) 0.91
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Candida albicans NADPH-P450 reductase: expression, purification, and characterization of recombinant protein. Biochem Biophys Res Commun (2010) 0.90
Nef induces apoptosis by activating JNK signaling pathway and inhibits NF-kappaB-dependent immune responses in Drosophila. J Cell Sci (2005) 0.90
Troglitazone acutely inhibits protein synthesis in endothelial cells via a novel mechanism involving protein phosphatase 2A-dependent p70 S6 kinase inhibition. Am J Physiol Cell Physiol (2006) 0.90
Bacillus infantis sp. nov. and Bacillus idriensis sp. nov., isolated from a patient with neonatal sepsis. Int J Syst Evol Microbiol (2006) 0.90
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BP75, bromodomain-containing M(r) 75,000 protein, binds dishevelled-1 and enhances Wnt signaling by inactivating glycogen synthase kinase-3 beta. Cancer Res (2003) 0.89
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Drosophila salt-inducible kinase (SIK) regulates starvation resistance through cAMP-response element-binding protein (CREB)-regulated transcription coactivator (CRTC). J Biol Chem (2010) 0.88
Toll-like receptors in peripheral nerve injury and neuropathic pain. Curr Top Microbiol Immunol (2009) 0.88
Exploring local structural organization of metabolic networks using subgraph patterns. J Theor Biol (2006) 0.88
PIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signaling. Mol Cell Biol (2013) 0.87
PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity. Mol Cells (2012) 0.87
Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway. Mol Cell Biol (2002) 0.87
Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans. Arch Biochem Biophys (2011) 0.87
AMPK links energy status to cell structure and mitosis. Biochem Biophys Res Commun (2007) 0.86
PINK1 and Parkin to control mitochondria remodeling. Anat Cell Biol (2010) 0.84
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Neuroprotective effect of SuHeXiang Wan in Drosophila models of Alzheimer's disease. J Ethnopharmacol (2011) 0.84
Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC). Mol Endocrinol (2007) 0.84