David Ginsburg

Author PubWeight™ 75.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol 2006 6.24
2 Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res 2005 5.71
3 Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet 2012 3.68
4 Plasminogen is a critical host pathogenicity factor for group A streptococcal infection. Science 2004 2.91
5 Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest 2005 2.50
6 Systemic antithrombotic effects of ADAMTS13. J Exp Med 2006 2.21
7 Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex. Nat Genet 2003 1.82
8 Trigger for group A streptococcal M1T1 invasive disease. FASEB J 2006 1.77
9 Homozygosity for factor V Leiden leads to enhanced thrombosis and atherosclerosis in mice. Circulation 2005 1.61
10 Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice. Blood 2009 1.58
11 ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity. Blood 2003 1.57
12 Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands. Proc Natl Acad Sci U S A 2002 1.55
13 LMAN1 and MCFD2 form a cargo receptor complex and interact with coagulation factor VIII in the early secretory pathway. J Biol Chem 2005 1.44
14 Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease. Nat Genet 2009 1.40
15 pak2a mutations cause cerebral hemorrhage in redhead zebrafish. Proc Natl Acad Sci U S A 2007 1.28
16 SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. Elife 2013 1.18
17 Enzymatically active ADAMTS13 variants are not inhibited by anti-ADAMTS13 autoantibodies: a novel therapeutic strategy? J Biol Chem 2005 1.16
18 Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association. Proc Natl Acad Sci U S A 2012 1.16
19 Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and factor V Leiden. Circulation 2002 1.15
20 Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2. Blood 2005 1.15
21 Cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex. Traffic 2006 1.15
22 The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis. Blood 2007 1.14
23 ADAMTS13 turns 3. Blood 2005 1.13
24 Reduced thrombin generation increases host susceptibility to group A streptococcal infection. Blood 2008 1.10
25 Treatment as prevention: preparing the way. J Int AIDS Soc 2011 1.09
26 Exocyst function is regulated by effector phosphorylation. Nat Cell Biol 2011 1.08
27 Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. Proc Natl Acad Sci U S A 2012 1.07
28 SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A 2012 1.03
29 The COPII pathway and hematologic disease. Blood 2012 1.03
30 Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase. Blood 2007 1.02
31 Selection on cis-regulatory variation at B4galnt2 and its influence on von Willebrand factor in house mice. Mol Biol Evol 2008 1.01
32 Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs. Hum Mol Genet 2006 1.00
33 Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin. Blood 2011 0.98
34 Parameters governing invasive disease propensity of non-M1 serotype group A streptococci. J Innate Immun 2010 0.97
35 The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood 2003 0.96
36 Sequence variation at multiple loci influences red cell hemoglobin concentration. Blood 2010 0.92
37 Biosynthetic origin and functional significance of murine platelet factor V. Blood 2003 0.92
38 Genotype-phenotype correlation in combined deficiency of factor V and factor VIII. Blood 2008 0.91
39 Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene. Blood 2006 0.91
40 Disruption of the Sec24d gene results in early embryonic lethality in the mouse. PLoS One 2013 0.91
41 The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele. Mamm Genome 2008 0.90
42 Asthmatic children have increased specific anti-Mycoplasma pneumoniae IgM but not IgG or IgE-values independent of history of respiratory tract infection. Pediatr Infect Dis J 2013 0.88
43 Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele. Proc Natl Acad Sci U S A 2010 0.87
44 Analysis of informed consent document utilization in a minimal-risk genetic study. Ann Intern Med 2011 0.87
45 Physical activity promotion: a local and state health department perspective. Prev Med 2009 0.83
46 Targeted gene sequencing identifies variants in the protein C and endothelial protein C receptor genes in patients with unprovoked venous thromboembolism. Arterioscler Thromb Vasc Biol 2013 0.81
47 A mutation in LMAN1 (ERGIC-53) causing combined factor V and factor VIII deficiency is prevalent in Jews originating from the island of Djerba in Tunisia. Blood Coagul Fibrinolysis 2004 0.81
48 Mammalian COPII coat component SEC24C is required for embryonic development in mice. J Biol Chem 2014 0.80
49 Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies. Toxicol Lett 2005 0.79
50 Getting secretory granules ready for prime time. Cell 2003 0.79
51 What a polyclonal antibody sees in von Willebrand factor. Thromb Res 2007 0.79
52 Transgenic overexpression of a stable Plasminogen Activator Inhibitor-1 variant. Thromb Res 2008 0.78
53 Congenital Hemorrhagic Disorders: New Insights into the Pathophysiology and Treatment of Hemophilia. Hematology Am Soc Hematol Educ Program 2000 0.78
54 Training the next generation of biomedical investigators in glycosciences. J Clin Invest 2016 0.76
55 Achieving South Africa's National Strategic Plan for HIV/AIDS. Lancet 2009 0.75
56 Functional display of platelet-binding VWF fragments on filamentous bacteriophage. PLoS One 2013 0.75
57 Introduction of Francis S. Collins. J Clin Invest 2015 0.75
58 Development and use of an evaluation tool for taste-testing activities by school-aged children. J Acad Nutr Diet 2012 0.75