PubRank

Stephen C Meredith

Author PubWeight™ 40.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Molecular structure of β-amyloid fibrils in Alzheimer's disease brain tissue. Cell 2013 4.02
2 Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance. Biophys J 2002 2.78
3 Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity 2002 2.18
4 Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity. Cancer Cell 2013 2.18
5 Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure. Proc Natl Acad Sci U S A 2009 2.15
6 The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation. Immunity 2010 2.02
7 Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid. Biochemistry 2005 1.78
8 Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure. J Mol Biol 2007 1.59
9 Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils. Biochemistry 2009 1.45
10 Peptide-based inhibitors of amyloid assembly. Methods Enzymol 2006 1.44
11 A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science 2006 1.44
12 Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel. Biophys J 2004 1.41
13 Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE. J Biol Chem 2007 1.41
14 Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest 2012 1.06
15 The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39). Biochemistry 2011 1.05
16 Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. Biochemistry 2003 1.00
17 Mechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect. Biophys J 2009 0.95
18 Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure. Biochemistry 2005 0.93
19 Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity. J Biol Chem 2007 0.89
20 Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene 2004 0.89
21 The specific amino acid sequence between helices 7 and 8 influences the binding specificity of human apolipoprotein A-I for high density lipoprotein (HDL) subclasses: a potential for HDL preferential generation. J Biol Chem 2008 0.88
22 Protein folding: sticky N17 speeds huntingtin pile-up. Nat Chem Biol 2010 0.86
23 Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids. Biochemistry 2006 0.84
24 Structural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection. J Am Chem Soc 2014 0.84
25 Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution. J Biol Chem 2001 0.84
26 Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature. J Am Chem Soc 2014 0.84
27 Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation. Biochemistry 2010 0.82
28 γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion. J Biol Chem 2012 0.82
29 High-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold. J Mol Biol 2008 0.81
30 Novel semisynthetic method for generating full length beta-amyloid peptides. Biopolymers 2010 0.77
31 Elucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation. Biochemistry 2015 0.76
32 Encapsulation and NMR on an aggregating peptide before fibrillogenesis. J Am Chem Soc 2006 0.75
33 Versatile cyclic templates for assembly of axially oriented ligands. Bioconjug Chem 2009 0.75