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About
Stephen C Meredith
Author PubWeight™ 40.94
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Top papers
Rank
Title
Journal
Year
PubWeight™
‹?›
1
Molecular structure of β-amyloid fibrils in Alzheimer's disease brain tissue.
Cell
2013
4.02
2
Supramolecular structure in full-length Alzheimer's beta-amyloid fibrils: evidence for a parallel beta-sheet organization from solid-state nuclear magnetic resonance.
Biophys J
2002
2.78
3
Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.
Immunity
2002
2.18
4
Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.
Cancer Cell
2013
2.18
5
Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure.
Proc Natl Acad Sci U S A
2009
2.15
6
The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation.
Immunity
2010
2.02
7
Abeta40-Lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid.
Biochemistry
2005
1.78
8
Flanking polyproline sequences inhibit beta-sheet structure in polyglutamine segments by inducing PPII-like helix structure.
J Mol Biol
2007
1.59
9
Evidence for novel beta-sheet structures in Iowa mutant beta-amyloid fibrils.
Biochemistry
2009
1.45
10
Peptide-based inhibitors of amyloid assembly.
Methods Enzymol
2006
1.44
11
A mutant chaperone converts a wild-type protein into a tumor-specific antigen.
Science
2006
1.44
12
Increasing the amphiphilicity of an amyloidogenic peptide changes the beta-sheet structure in the fibrils from antiparallel to parallel.
Biophys J
2004
1.41
13
Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE.
J Biol Chem
2007
1.41
14
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal.
J Clin Invest
2012
1.06
15
The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39).
Biochemistry
2011
1.05
16
Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.
Biochemistry
2003
1.00
17
Mechanism of cis-inhibition of polyQ fibrillation by polyP: PPII oligomers and the hydrophobic effect.
Biophys J
2009
0.95
18
Helix-turn-helix peptides that form alpha-helical fibrils: turn sequences drive fibril structure.
Biochemistry
2005
0.93
19
Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity.
J Biol Chem
2007
0.89
20
Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors.
Oncogene
2004
0.89
21
The specific amino acid sequence between helices 7 and 8 influences the binding specificity of human apolipoprotein A-I for high density lipoprotein (HDL) subclasses: a potential for HDL preferential generation.
J Biol Chem
2008
0.88
22
Protein folding: sticky N17 speeds huntingtin pile-up.
Nat Chem Biol
2010
0.86
23
Spatial separation of beta-sheet domains of beta-amyloid: disruption of each beta-sheet by N-methyl amino acids.
Biochemistry
2006
0.84
24
Structural heterogeneity in transmembrane amyloid precursor protein homodimer is a consequence of environmental selection.
J Am Chem Soc
2014
0.84
25
Apolipoprotein A-I alpha -helices 7 and 8 modulate high density lipoprotein subclass distribution.
J Biol Chem
2001
0.84
26
Transmembrane fragment structures of amyloid precursor protein depend on membrane surface curvature.
J Am Chem Soc
2014
0.84
27
Chaperone-like N-methyl peptide inhibitors of polyglutamine aggregation.
Biochemistry
2010
0.82
28
γδ T cell receptors recognize the non-classical major histocompatibility complex (MHC) molecule T22 via conserved anchor residues in a MHC peptide-like fashion.
J Biol Chem
2012
0.82
29
High-resolution structure of a self-assembly-competent form of a hydrophobic peptide captured in a soluble beta-sheet scaffold.
J Mol Biol
2008
0.81
30
Novel semisynthetic method for generating full length beta-amyloid peptides.
Biopolymers
2010
0.77
31
Elucidation of the Aggregation Pathways of Helix-Turn-Helix Peptides: Stabilization at the Turn Region Is Critical for Fibril Formation.
Biochemistry
2015
0.76
32
Encapsulation and NMR on an aggregating peptide before fibrillogenesis.
J Am Chem Soc
2006
0.75
33
Versatile cyclic templates for assembly of axially oriented ligands.
Bioconjug Chem
2009
0.75