Obstructive sleep apnea and coronary artery disease: from pathophysiology to clinical implications.

PubWeight™: 0.89‹?›

🔗 View Article (PMC 3649685)

Published in Pulm Med on April 15, 2013

Authors

Fernando De Torres-Alba1, Daniele Gemma, Eduardo Armada-Romero, Juan Ramón Rey-Blas, Esteban López-de-Sá, José Luis López-Sendon

Author Affiliations

1: Acute Cardiac Care Unit, Department of Cardiology, La Paz University Hospital, Paseo de la Castellana 261, 28046 Madrid, Spain.

Associated clinical trials:

Continuous Positive Airway Pressure Treatment of Obstructive Sleep Apnea to Prevent Cardiovascular Disease (SAVE) | NCT00738179

NCT 01335087

Articles cited by this

(truncated to the top 100)

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA (2003) 97.28

The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med (1993) 35.93

Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation (2012) 30.79

ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J (2012) 18.18

Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med (2000) 18.12

Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet (2005) 17.31

ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J (2011) 13.10

Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med (2001) 12.29

Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA (2000) 12.27

Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults. J Clin Sleep Med (2009) 8.18

Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98

Lifetime risk of developing coronary heart disease. Lancet (1999) 7.54

Ischemia and reperfusion--from mechanism to translation. Nat Med (2011) 6.64

The epidemiology of adult obstructive sleep apnea. Proc Am Thorac Soc (2008) 6.33

Effect of sleep loss on C-reactive protein, an inflammatory marker of cardiovascular risk. J Am Coll Cardiol (2004) 6.08

Predictors of sleep-disordered breathing in community-dwelling adults: the Sleep Heart Health Study. Arch Intern Med (2002) 5.98

Role of endothelial dysfunction in atherosclerosis. Circulation (2004) 5.77

Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation (2010) 5.70

Elevated C-reactive protein in patients with obstructive sleep apnea. Circulation (2002) 4.77

Elevation of plasma cytokines in disorders of excessive daytime sleepiness: role of sleep disturbance and obesity. J Clin Endocrinol Metab (1997) 4.47

Current concepts of the pathogenesis of the acute coronary syndromes. Circulation (2001) 4.23

Day-night pattern of sudden death in obstructive sleep apnea. N Engl J Med (2005) 3.84

Obstructive sleep apnoea and its cardiovascular consequences. Lancet (2008) 3.73

Association of sleep apnea and type II diabetes: a population-based study. Am J Respir Crit Care Med (2005) 3.42

Impaired endothelial function in persons with obstructive sleep apnoea: impact of obesity. Heart (2012) 3.36

Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med (2003) 3.26

Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA (2012) 3.24

Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up. Am J Respir Crit Care Med (2002) 3.17

Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med (2002) 3.16

Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med (2007) 3.07

CPAP effect on recurrent episodes in patients with sleep apnea and myocardial infarction. Int J Cardiol (2013) 3.06

Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation (2005) 2.99

Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure. Circulation (2003) 2.98

Association of diet, exercise, and smoking modification with risk of early cardiovascular events after acute coronary syndromes. Circulation (2010) 2.88

Obstructive sleep apnea and type 2 diabetes: interacting epidemics. Chest (2008) 2.83

Early signs of atherosclerosis in obstructive sleep apnea. Am J Respir Crit Care Med (2005) 2.67

Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome. Chest (2005) 2.65

Chronic intermittent hypoxia induces atherosclerosis. Am J Respir Crit Care Med (2007) 2.62

Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk. Am J Respir Crit Care Med (2007) 2.50

Increased carotid intima-media thickness and serum inflammatory markers in obstructive sleep apnea. Am J Respir Crit Care Med (2005) 2.35

Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea. Circulation (2008) 2.28

Augmented resting sympathetic activity in awake patients with obstructive sleep apnea. Chest (1993) 2.24

Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study. Ann Intern Med (2012) 2.23

Obstructive sleep apnea is associated with increased high-sensitivity cardiac troponin T levels. Chest (2012) 2.21

Sleep-disordered breathing and coronary artery disease: long-term prognosis. Am J Respir Crit Care Med (2001) 2.19

Is there a correlation between OSAS duration/severity and carotid intima-media thickness? Respir Med (2012) 2.19

Obstructive sleep apnea in patients admitted for acute myocardial infarction. Prevalence, predictors, and effect on microvascular perfusion. Chest (2009) 2.18

Benefits of obstructive sleep apnoea treatment in coronary artery disease: a long-term follow-up study. Eur Heart J (2004) 2.01

Independent association between obstructive sleep apnea and noncalcified coronary plaque demonstrated by noninvasive coronary computed tomography angiography. Clin Cardiol (2012) 2.01

Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation (2005) 1.99

Temporal changes in resting heart rate and deaths from ischemic heart disease. JAMA (2011) 1.94

C-reactive protein is associated with sleep disordered breathing independent of adiposity. Sleep (2007) 1.79

An independent association between obstructive sleep apnoea and coronary artery disease. Eur Respir J (1999) 1.78

Obstructive sleep apnea and dyslipidemia: evidence and underlying mechanism. Sleep Breath (2012) 1.76

Respiratory disturbance index: an independent predictor of mortality in coronary artery disease. Am J Respir Crit Care Med (2000) 1.76

Occurrence of coronary collateral vessels in patients with sleep apnea and total coronary occlusion. Chest (2009) 1.75

ST-segment depression during sleep in obstructive sleep apnea. Am J Cardiol (1993) 1.73

Endothelial dysfunction in obstructive sleep apnea measured by peripheral arterial tone response in the finger to reactive hyperemia. Sleep (2005) 1.67

Oxidative stress in obstructive sleep apnea. Chest (2005) 1.65

Cardiovascular mortality in obstructive sleep apnea in the elderly: role of long-term continuous positive airway pressure treatment: a prospective observational study. Am J Respir Crit Care Med (2012) 1.63

Sleep-disordered breathing in men with coronary artery disease. Chest (1996) 1.58

Sleep apnea and cardiovascular disease: a bidirectional relationship. Circulation (2012) 1.57

Obstructive sleep apnea: an emerging risk factor for atherosclerosis. Chest (2011) 1.57

Impact of obstructive sleep apnea on clinical and angiographic outcomes following percutaneous coronary intervention in patients with acute coronary syndrome. Am J Cardiol (2006) 1.56

Interindividual heterogeneity in the hypoxic regulation of VEGF: significance for the development of the coronary artery collateral circulation. Circulation (1999) 1.55

Oxidized lipoproteins degrade the endothelial surface layer : implications for platelet-endothelial cell adhesion. Circulation (2000) 1.53

Oxidative stress and atherosclerosis. Pathophysiology (2006) 1.52

Day-night variation of acute myocardial infarction in obstructive sleep apnea. J Am Coll Cardiol (2008) 1.50

Treatment of obstructive sleep apnea is associated with decreased cardiac death after percutaneous coronary intervention. J Am Coll Cardiol (2007) 1.49

Independent association between obstructive sleep apnea and subclinical coronary artery disease. Chest (2008) 1.47

Increased risk of stroke in patients with coronary artery disease and sleep apnea: a 10-year follow-up. Circulation (2008) 1.45

Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea: a randomised trial. Thorax (2008) 1.42

C-reactive protein and sleep-disordered breathing. Sleep (2004) 1.41

Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl Physiol (1985) (2002) 1.38

Hypoxia-inducible factor 1alpha polymorphism and coronary collaterals in patients with ischemic heart disease. Chest (2005) 1.35

Spontaneous platelet activation and aggregation during obstructive sleep apnea and its response to therapy with nasal continuous positive airway pressure. A preliminary investigation. Chest (1995) 1.30

Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy. Thorax (2000) 1.27

Effects of NCPAP therapy on fibrinogen levels in obstructive sleep apnea syndrome. Am J Respir Crit Care Med (1996) 1.26

Obstructive sleep apnea as a risk factor for coronary events or cardiovascular death. Sleep Breath (2009) 1.25

Obstructive sleep apnea as a risk marker in coronary artery disease. Cardiology (1999) 1.24

Sleep apnoea and nocturnal angina. Lancet (1995) 1.19

Abnormal lipid peroxidation in patients with sleep apnoea. Eur Respir J (2000) 1.19

The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome. Chest (2004) 1.17

Under-diagnosis of sleep apnea in patients after acute myocardial infarction. J Am Coll Cardiol (2010) 1.15

Role of obstructive sleep apnea in cardiovascular disease. Curr Opin Cardiol (2011) 1.12

Sleep apnea-hypopnea syndrome and acute coronary syndrome - an association not to forget. Rev Port Pneumol (2011) 1.11

Obstructive sleep apnoea inhibits the recovery of left ventricular function in patients with acute myocardial infarction. Eur Heart J (2006) 1.11

Hemostatic alterations in patients with obstructive sleep apnea and the implications for cardiovascular disease. Chest (2003) 1.10

Obstructive sleep apnea and acute myocardial infarction severity: ischemic preconditioning? Sleep Breath (2012) 1.09

Nocturnal ischemic events in patients with obstructive sleep apnea syndrome and ischemic heart disease: effects of continuous positive air pressure treatment. J Am Coll Cardiol (1999) 1.09

Association between sleep apnea severity and blood coagulability: Treatment effects of nasal continuous positive airway pressure. Sleep Breath (2006) 1.09

Endothelial dysfunction in adults with obstructive sleep apnea. Adv Cardiol (2011) 1.07

Severe obstructive sleep apnea and outcomes following myocardial infarction. J Clin Sleep Med (2011) 1.06

Lymphocyte activation as a possible measure of atherosclerotic risk in patients with sleep apnea. Ann N Y Acad Sci (2005) 1.06

Obesity, obstructive sleep apnoea and metabolic syndrome. Respirology (2012) 1.05

Morbidities associated with obstructive sleep apnea. Expert Rev Respir Med (2012) 0.99

Oxidative stress in obstructive sleep apnea: putative pathways to the cardiovascular complications. Antioxid Redox Signal (2008) 0.99

Endothelial progenitor cells in acute myocardial infarction and sleep-disordered breathing. Am J Respir Crit Care Med (2012) 0.98

Ischemic preconditioning as a possible explanation for the age decline relative mortality in sleep apnea. Med Hypotheses (2006) 0.97

The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. J Clin Sleep Med (2011) 0.95