Published in Immunology on September 01, 2013
Heme Oxygenase-1 in Kidney Health and Disease. Antioxid Redox Signal (2016) 0.82
Escherichia coli heme oxygenase modulates host innate immune responses. Microbiol Immunol (2015) 0.76
Therapeutic potential of HO-1 in autoimmune diseases. Inflammation (2014) 0.75
Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance. Immunology (2016) 0.75
Carbon monoxide inhibits T cell activation in target organs during systemic lupus erythematosus. Clin Exp Immunol (2015) 0.75
Myeloid-derived suppressor cells and myeloid regulatory cells in cancer and autoimmune disorders. Exp Ther Med (2016) 0.75
Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 26.08
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science (2003) 14.04
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications. Physiol Rev (2006) 7.76
Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev (2008) 5.34
Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature (1996) 5.25
Inducing tumor immunity through the selective engagement of activating Fcgamma receptors on dendritic cells. J Exp Med (2002) 2.54
B cells as therapeutic targets in SLE. Nat Rev Rheumatol (2010) 2.25
Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am J Pathol (2004) 2.09
Remnants of secondarily necrotic cells fuel inflammation in systemic lupus erythematosus. Arthritis Rheum (2009) 2.04
Global natural regulatory T cell depletion in active systemic lupus erythematosus. J Immunol (2005) 2.00
Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase. Kidney Int (2010) 1.88
Clearance deficiency and systemic lupus erythematosus (SLE). J Autoimmun (2007) 1.87
Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression. Blood (2005) 1.86
T cells as therapeutic targets in SLE. Nat Rev Rheumatol (2010) 1.75
Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. J Clin Invest (2007) 1.67
Subsets, expansion and activation of myeloid-derived suppressor cells. Med Microbiol Immunol (2010) 1.67
The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells. J Immunol (2010) 1.30
Cytokines as therapeutic targets in SLE. Nat Rev Rheumatol (2010) 1.25
The pathophysiologic role of monocytes and macrophages in systemic lupus erythematosus: a reappraisal. Semin Arthritis Rheum (2009) 1.22
B cell biology and dysfunction in SLE. Bull NYU Hosp Jt Dis (2007) 1.22
Current treatment of lupus nephritis. Lupus (2008) 1.20
Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity. J Immunol (2009) 1.19
Identification of regulatory T cells in systemic lupus erythematosus. Autoimmun Rev (2009) 1.06
Heme oxygenase-1 production by peripheral blood monocytes during acute inflammatory illnesses of children. Exp Biol Med (Maywood) (2003) 1.06
Cellular interactions in the pathogenesis of lupus nephritis: the role of T cells and macrophages in the amplification of the inflammatory process in the kidney. Lupus (1998) 1.05
Anti-double-stranded DNA antibodies, nucleosomes, and systemic lupus erythematosus: a time for new paradigms? Arthritis Rheum (2003) 1.04
Tolerogenic dendritic cells actively inhibit T cells through heme oxygenase-1 in rodents and in nonhuman primates. FASEB J (2009) 1.04
Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells. Exp Dermatol (2007) 1.02
Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome. Arthritis Res Ther (2011) 1.01
Modulation of renal disease in MRL/lpr mice by pharmacologic inhibition of inducible nitric oxide synthase. Kidney Int (2002) 1.01
Receptors for IgG complexes activate synthesis of monocyte chemoattractant peptide 1 and colony-stimulating factor 1. Proc Natl Acad Sci U S A (1992) 1.00
Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. Arthritis Rheum (2009) 1.00
Reduction of forkhead box P3 levels in CD4+CD25high T cells in patients with new-onset systemic lupus erythematosus. Clin Exp Immunol (2008) 1.00
Fc receptor genes and the systemic lupus erythematosus diathesis. Autoimmunity (2007) 0.99
The TNFalpha locus is altered in monocytes from patients with systemic lupus erythematosus. Clin Immunol (2007) 0.99
Chemical induction of HO-1 suppresses lupus nephritis by reducing local iNOS expression and synthesis of anti-dsDNA antibody. Clin Exp Immunol (2004) 0.95
Pathogenic anti-nucleosome antibodies. Lupus (2008) 0.92
Expression of MRP8 and MRP14 by macrophages is a marker for severe forms of glomerulonephritis. J Leukoc Biol (2003) 0.91
IL-17 is a potent synergistic factor with GM-CSF in mice in stimulating myelopoiesis, dendritic cell expansion, proliferation, and functional enhancement. Exp Hematol (2010) 0.91
Expansion and high proliferative potential of the macrophage system throughout life time of lupus-prone NZB/W and MRL lpr/lpr mice. Lack of down-regulation of extramedullar macrophage proliferation in the postnatal period. Eur J Immunol (1991) 0.90
Phenotypic analysis of IL-10-treated, monocyte-derived dendritic cells in patients with systemic lupus erythematosus. Scand J Immunol (2006) 0.88
Contribution of NZB autoimmunity 2 to Y-linked autoimmune acceleration-induced monocytosis in association with murine systemic lupus. J Immunol (2006) 0.88
T- and B-cell abnormalities in systemic lupus. J Invest Dermatol (1993) 0.85
Carbon monoxide-treated dendritic cells decrease β1-integrin induction on CD8⁺ T cells and protect from type 1 diabetes. Eur J Immunol (2012) 0.80
Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin. Am J Physiol (1991) 0.80
IgG keeps virulent Salmonella from evading dendritic cell uptake. Immunology (2012) 0.80
Activated microglia are less vulnerable to hemin toxicity due to nitric oxide-dependent inhibition of JNK and p38 MAPK activation. J Immunol (2011) 0.79
Haem oxygenase 1 expression is altered in monocytes from patients with systemic lupus erythematosus. Immunology (2012) 0.79
Depletion of cytochrome P-450 by thyroid hormone and cobalt-protoporphyrin IX in rat liver: evidence that susceptibility varies among forms of the heme protein. Pharmacology (1995) 0.78
Knockout rats via embryo microinjection of zinc-finger nucleases. Science (2009) 12.33
Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol (2011) 8.45
Activated TCRs remain marked for internalization after dissociation from pMHC. Nat Immunol (2002) 3.01
Overexpression of transforming growth factor-beta1 stabilizes already-formed aortic aneurysms: a first approach to induction of functional healing by endovascular gene therapy. Circulation (2005) 2.02
A role for heme oxygenase-1 in the immunosuppressive effect of adult rat and human mesenchymal stem cells. Blood (2007) 1.91
Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression. Blood (2005) 1.86
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood (2007) 1.83
Maternal and fetal factors associated with mortality and morbidity in a multi-racial/ethnic registry of anti-SSA/Ro-associated cardiac neonatal lupus. Circulation (2011) 1.68
Safety and efficacy of regional intravenous (r.i.) versus intramuscular (i.m.) delivery of rAAV1 and rAAV8 to nonhuman primate skeletal muscle. Mol Ther (2008) 1.63
Characterization of immunoglobulin heavy chain knockout rats. Eur J Immunol (2010) 1.63
Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum. Cancer Res (2006) 1.55
Evaluation of fetuses in a study of intravenous immunoglobulin as preventive therapy for congenital heart block: Results of a multicenter, prospective, open-label clinical trial. Arthritis Rheum (2010) 1.52
Generation of gene-specific mutated rats using zinc-finger nucleases. Methods Mol Biol (2010) 1.51
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell. Proc Natl Acad Sci U S A (2005) 1.49
Lentiviral vectors that express UGT1A1 in liver and contain miR-142 target sequences normalize hyperbilirubinemia in Gunn rats. Gastroenterology (2010) 1.48
IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cells. Eur J Immunol (2007) 1.46
Gestational hypothyroidism increases the severity of experimental autoimmune encephalomyelitis in adult offspring. Thyroid (2013) 1.41
Inhibition of chronic rejection and development of tolerogenic T cells after ICOS-ICOSL and CD40-CD40L co-stimulation blockade. Transplantation (2005) 1.41
A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles. Hum Gene Ther (2002) 1.37
Salmonella escape from antigen presentation can be overcome by targeting bacteria to Fc gamma receptors on dendritic cells. J Immunol (2004) 1.33
Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J Immunol (2006) 1.32
CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase. J Clin Invest (2007) 1.23
Zinc-finger nucleases: a powerful tool for genetic engineering of animals. Transgenic Res (2009) 1.22
Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity. J Immunol (2009) 1.22
Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. FASEB J (2005) 1.21
Virulent Salmonella enterica serovar typhimurium evades adaptive immunity by preventing dendritic cells from activating T cells. Infect Immun (2006) 1.21
Lack of immunotoxicity after regional intravenous (RI) delivery of rAAV to nonhuman primate skeletal muscle. Mol Ther (2009) 1.21
Maternal use of hydroxychloroquine is associated with a reduced risk of recurrent anti-SSA/Ro-antibody-associated cardiac manifestations of neonatal lupus. Circulation (2012) 1.20
Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine. Ann Rheum Dis (2010) 1.19
Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes. Hypertension (2014) 1.19
T cell immunity evasion by virulent Salmonella enterica. Immunol Lett (2007) 1.19
Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity. J Immunol (2009) 1.19
Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells. Proc Natl Acad Sci U S A (2008) 1.16
Mesenchymal stem cell therapy prevents interstitial fibrosis and tubular atrophy in a rat kidney allograft model. Stem Cells Dev (2012) 1.11
Prospective evaluation of fetuses with autoimmune-associated congenital heart block followed in the PR Interval and Dexamethasone Evaluation (PRIDE) Study. Am J Cardiol (2009) 1.10
Andrographolide interferes with T cell activation and reduces experimental autoimmune encephalomyelitis in the mouse. J Pharmacol Exp Ther (2004) 1.10
Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG. Proc Natl Acad Sci U S A (2008) 1.08
Transgenic modifications of the rat genome. Transgenic Res (2005) 1.08
Macrophages expressing heme oxygenase-1 improve renal function in ischemia/reperfusion injury. Mol Ther (2010) 1.08
Rapid and accurate determination of zygosity in transgenic animals by real-time quantitative PCR. Transgenic Res (2002) 1.06
Cutaneous manifestations of neonatal lupus and risk of subsequent congenital heart block. Arthritis Rheum (2010) 1.06
Aldosterone as a modulator of immunity: implications in the organ damage. J Hypertens (2011) 1.05
Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance. J Immunol (2010) 1.05
Gene transfer of heme oxygenase-1 and carbon monoxide delivery inhibit chronic rejection. Am J Transplant (2002) 1.04
B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcgammaRIIb, which are modulated by anti-tumor necrosis factor therapy. Arthritis Res Ther (2010) 1.04
Identification of a new member of the CD20/FcepsilonRIbeta family overexpressed in tolerated allografts. Am J Transplant (2005) 1.02
Inhibition of nuclear factor-kappa B enhances the capacity of immature dendritic cells to induce antigen-specific tolerance in experimental autoimmune encephalomyelitis. J Pharmacol Exp Ther (2006) 1.01
Modulation of nuclear factor-kappaB activity can influence the susceptibility to systemic lupus erythematosus. Immunology (2008) 1.01
Host immunity during RSV pathogenesis. Int Immunopharmacol (2008) 1.01
Bone-marrow-derived macrophages genetically modified to produce IL-10 reduce injury in experimental glomerulonephritis. Mol Ther (2002) 1.01
Generation of Rag1-knockout immunodeficient rats and mice using engineered meganucleases. FASEB J (2012) 1.00
Modulation of T cell function by TCR/pMHC binding kinetics. Immunobiology (2006) 1.00
Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation. J Cell Mol Med (2009) 1.00
The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology (2007) 0.98
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation. J Immunol (2011) 0.97
Efficient lung recruitment of respiratory syncytial virus-specific Th1 cells induced by recombinant bacillus Calmette-Guérin promotes virus clearance and protects from infection. J Immunol (2010) 0.96
Pronuclear DNA injection for the production of transgenic rats. Methods Mol Biol (2009) 0.95
The capacity of Salmonella to survive inside dendritic cells and prevent antigen presentation to T cells is host specific. Immunology (2008) 0.95
Human CD1d knock-in mouse model demonstrates potent antitumor potential of human CD1d-restricted invariant natural killer T cells. Proc Natl Acad Sci U S A (2013) 0.94
Immune complex-induced enhancement of bacterial antigen presentation requires Fcgamma receptor III expression on dendritic cells. Proc Natl Acad Sci U S A (2007) 0.94
Research priorities for neglected infectious diseases in Latin America and the Caribbean region. PLoS Negl Trop Dis (2010) 0.94
The C-type lectin-like receptor CLEC-1, expressed by myeloid cells and endothelial cells, is up-regulated by immunoregulatory mediators and moderates T cell activation. J Immunol (2009) 0.93
Transgenic expression of CTLA4-Ig by fetal pig neurons for xenotransplantation. Transgenic Res (2005) 0.93
Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells. Am J Transplant (2005) 0.93
Anti-CD28 antibodies modify regulatory mechanisms and reinforce tolerance in CD40Ig-treated heart allograft recipients. J Immunol (2007) 0.92
Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response. Microbes Infect (2012) 0.92
Mechanisms used by virulent Salmonella to impair dendritic cell function and evade adaptive immunity. Immunology (2012) 0.92
Suppression of experimental crescentic glomerulonephritis by interleukin-10 gene transfer. Kidney Int (2004) 0.92
Interplay between thermal and immune ecology: effect of environmental temperature on insect immune response and energetic costs after an immune challenge. J Insect Physiol (2011) 0.90
The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity. Eur J Immunol (2009) 0.90
Analysis by quantitative PCR of zygosity in genetically modified organisms. Methods Mol Biol (2010) 0.89
Excision of an unstable pathogenicity island in Salmonella enterica serovar Enteritidis is induced during infection of phagocytic cells. PLoS One (2011) 0.89
Local cytokine response upon respiratory syncytial virus infection. Immunol Lett (2010) 0.89
Immunoregulatory properties of heme oxygenase-1. Methods Mol Biol (2011) 0.89
Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation. J Immunol (2009) 0.89
Respiratory syncytial virus infection and immunity. Rev Med Virol (2012) 0.88
Characterization of human CD55 and CD59 transgenic pigs and kidney xenotransplantation in the pig-to-baboon combination. Transplantation (2004) 0.88
β2-Adrenoreceptor agonist inhibits antigen cross-presentation by dendritic cells. J Immunol (2013) 0.88
Molecular interactions between dendritic cells and Salmonella: escape from adaptive immunity and implications on pathogenesis. Crit Rev Immunol (2005) 0.88
High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region. J Immunol (2013) 0.88
Over-expression of heme oxygenase-1 by adenoviral gene transfer improves pregnancy outcome in a murine model of abortion. J Reprod Immunol (2005) 0.88
Melanocortin 1 receptor is expressed by uveal malignant melanoma and can be considered a new target for diagnosis and immunotherapy. Invest Ophthalmol Vis Sci (2007) 0.88
Promises and obstacles for the blockade of CD40-CD40L interactions in allotransplantation. Transplantation (2008) 0.87
Modulation of the dendritic cell-T-cell synapse to promote pathogen immunity and prevent autoimmunity. Immunotherapy (2011) 0.87
Impairment of T cell immunity by the respiratory syncytial virus: targeting virulence mechanisms for therapy and prophylaxis. Curr Med Chem (2009) 0.87
Activating and inhibitory Fcgamma receptors can differentially modulate T cell-mediated autoimmunity. Eur J Immunol (2008) 0.87