Genetic instrumental variable studies of effects of prenatal risk factors.

PubWeight™: 0.78‹?›

🔗 View Article (PMC 3690512)

Published in Biodemography Soc Biol on January 01, 2013

Authors

George L Wehby1, Stephanie von Hinke Kessler Scholder

Author Affiliations

1: Department of Health Management and Policy, University of Iowa, Iowa City, IA, USA. george-wehby@uiowa.edu

Articles cited by this

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature (2008) 18.21

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol (2003) 16.71

Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99

ALSPAC--the Avon Longitudinal Study of Parents and Children. I. Study methodology. Paediatr Perinat Epidemiol (2001) 14.31

Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet (2007) 13.62

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet (2006) 13.16

Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. Nat Genet (2008) 12.43

Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med (2008) 9.39

Recognition of the fetal alcohol syndrome in early infancy. Lancet (1973) 8.57

Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55

Problems of reporting genetic associations with complex outcomes. Lancet (2003) 8.11

Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet (2010) 6.68

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat Genet (2009) 6.39

Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry (2008) 6.37

The Danish National Birth Cohort--its background, structure and aim. Scand J Public Health (2001) 6.09

Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet (1998) 6.04

An obesity-associated FTO gene variant and increased energy intake in children. N Engl J Med (2008) 5.88

Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol (2004) 5.07

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91

Obesity associated genetic variation in FTO is associated with diminished satiety. J Clin Endocrinol Metab (2008) 3.80

Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med (2007) 3.71

Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies. BMC Public Health (2007) 3.64

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37

A note on the influence of maternal inebriety on the offspring. 1899. Int J Epidemiol (2011) 3.33

A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genet (2008) 3.25

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. PLoS Genet (2010) 3.21

The fat mass- and obesity-associated locus and dietary intake in children. Am J Clin Nutr (2008) 3.18

A genome screen of maximum number of drinks as an alcoholism phenotype. Am J Med Genet (2000) 3.14

Mendelian randomisation and causal inference in observational epidemiology. PLoS Med (2008) 3.12

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes. Am J Med Genet B Neuropsychiatr Genet (2009) 2.86

Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity (Silver Spring) (2008) 2.68

Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med (2008) 2.61

Nicotinic receptor gene variants influence susceptibility to heavy smoking. Cancer Epidemiol Biomarkers Prev (2008) 2.58

PCA-correlated SNPs for structure identification in worldwide human populations. PLoS Genet (2007) 2.36

Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis. Hum Mol Genet (2008) 2.26

Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15. Hum Mol Genet (2009) 2.22

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. Hum Mol Genet (2009) 2.02

Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype. Hypertension (2009) 2.01

Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabetes (2008) 1.96

Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. Addiction (2008) 1.91

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Nicotine Tob Res (2009) 1.84

'Mendelian randomization' equals instrumental variable analysis with genetic instruments. Stat Med (2008) 1.77

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study. Eur Heart J (2008) 1.76

FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies. Diabetes (2011) 1.75

Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence. Fertil Steril (2008) 1.75

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68

The effects of maternal body mass index on pregnancy outcome. Eur J Epidemiol (2009) 1.67

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health. Genes Nutr (2010) 1.65

Combined effects of MC4R and FTO common genetic variants on obesity in European general populations. J Mol Med (Berl) (2009) 1.62

Do alcohol-metabolizing enzyme gene polymorphisms increase the risk of alcoholism and alcoholic liver disease? Hepatology (2006) 1.51

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies. Neuropsychopharmacology (2006) 1.45

Maternal BMI and preterm birth: a systematic review of the literature with meta-analysis. J Matern Fetal Neonatal Med (2009) 1.43

A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women. Hum Mol Genet (2009) 1.32

Secular trend of earlier onset of menarche with increasing obesity in black and white girls: the Bogalusa Heart Study. Ethn Dis (1999) 1.32

From GWAS to biology: lessons from FTO. Ann N Y Acad Sci (2011) 1.31

ADH genotypes and alcohol use and dependence in Europeans. Alcohol Clin Exp Res (1998) 1.31

Genetic associations of alcohol dehydrogenase with alcohol use disorders and endophenotypes in white college students. J Abnorm Psychol (2005) 1.28

Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis. World J Gastroenterol (2010) 1.26

An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumference. Diabet Med (2011) 1.23

Genetic polymorphisms in 15q25 and 19q13 loci, cotinine levels, and risk of lung cancer in EPIC. Cancer Epidemiol Biomarkers Prev (2011) 1.21

ADH single nucleotide polymorphism associations with alcohol metabolism in vivo. Hum Mol Genet (2009) 1.18

Prenatal care demand and its effects on birth outcomes by birth defect status in Argentina. Econ Hum Biol (2008) 1.16

Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am J Clin Nutr (2009) 1.15

Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans. Alcohol Clin Exp Res (2009) 1.14

Simultaneous-equation estimation in a clinical trial of the effect of smoking on birth weight. Biometrics (1989) 1.14

Analyses of shared genetic factors between asthma and obesity in children. J Allergy Clin Immunol (2010) 1.13

Mendelian randomization: the use of genes in instrumental variable analyses. Health Econ (2011) 1.12

The FTO gene and obesity in a large Eastern European population sample: the HAPIEE study. Obesity (Silver Spring) (2008) 1.11

Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations. Alcohol Clin Exp Res (2010) 1.11

Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G x E) interaction. Int J Obes (Lond) (2008) 1.11

The Impact of Maternal Smoking during Pregnancy on Early Child Neurodevelopment. J Hum Cap (2011) 1.10

Epidemiology, radiology, and genetics of nicotine dependence in COPD. Respir Res (2011) 1.10

Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-Asians. Alcohol Clin Exp Res (2006) 1.05

A field synopsis and meta-analysis of genetic association studies in peripheral arterial disease: The CUMAGAS-PAD database. Am J Epidemiol (2009) 1.03

Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study. J Clin Oncol (2011) 1.01

Genetic lotteries within families. J Health Econ (2011) 1.00

Maternal and offspring adiposity-related genetic variants and gestational weight gain. Am J Clin Nutr (2011) 1.00

Mendelian Randomisation Study of Childhood BMI and Early Menarche. J Obes (2011) 0.99

GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS. Health Serv Outcomes Res Methodol (2011) 0.98

Meta-analysis of ADH1B and ALDH2 polymorphisms and esophageal cancer risk in China. World J Gastroenterol (2010) 0.97

Obesity, FTO gene variant, and energy intake in children. N Engl J Med (2009) 0.95

Nicotinic acetylcholine receptors and predisposition to lung cancer. Curr Opin Oncol (2011) 0.94

Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland. Int J Cancer (2007) 0.92

Genetic analysis of the maximum drinks phenotype. BMC Genet (2005) 0.90

Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study. Eur J Endocrinol (2010) 0.89

Smoking and body weight: evidence using genetic instruments. Econ Hum Biol (2011) 0.88

ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis. PLoS One (2010) 0.88

The promise and pitfalls of combining genetic and economic research. Health Econ (2011) 0.87

Genetic associations with acute stress-related changes in eating in the absence of hunger. Patient Educ Couns (2010) 0.86

Child height, health and human capital: Evidence using genetic markers. Eur Econ Rev (2013) 0.85

Relation among alcohol dehydrogenase 2 polymorphism, alcohol consumption, and levels of gamma-glutamyltransferase. Alcohol (2003) 0.84

A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs. Am J Med Genet B Neuropsychiatr Genet (2008) 0.84

A genetic instrumental variables analysis of the effects of prenatal smoking on birth weight: evidence from two samples. Biodemography Soc Biol (2011) 0.82

Alcohol-dehydrogenase (ADH1B) Arg48His polymorphism in Basque Country patients with oral and laryngeal cancer: preliminary study. Anticancer Res (2011) 0.79

[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]. Ugeskr Laeger (2008) 0.75