Published in Aging Cell on July 08, 2013
Manganese Toxicity Upon Overexposure: a Decade in Review. Curr Environ Health Rep (2015) 0.97
Elevated adult neurogenesis in brain subventricular zone following in vivo manganese exposure: roles of copper and DMT1. Toxicol Sci (2015) 0.80
X-ray fluorescence imaging of the hippocampal formation after manganese exposure. Metallomics (2013) 0.80
Copper accumulation in rodent brain astrocytes: A species difference. J Trace Elem Med Biol (2016) 0.76
Aberrant Adult Neurogenesis in the Subventricular Zone-Rostral Migratory Stream-Olfactory Bulb System Following Subchronic Manganese Exposure. Toxicol Sci (2016) 0.76
Age-dependent increase of brain copper levels and expressions of copper regulatory proteins in the subventricular zone and choroid plexus. Front Mol Neurosci (2015) 0.76
Metallothionein, Copper and Alpha-Synuclein in Alpha-Synucleinopathies. Front Neurosci (2017) 0.75
Mapping Alterations to the Endogenous Elemental Distribution within the Lateral Ventricles and Choroid Plexus in Brain Disorders Using X-Ray Fluorescence Imaging. PLoS One (2016) 0.75
On the nature of the Cu-rich aggregates in brain astrocytes. Redox Biol (2016) 0.75
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell (1999) 15.87
Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci (2006) 12.23
Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature (2006) 8.06
Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J Neurosci (1997) 6.74
Identification of a neural stem cell in the adult mammalian central nervous system. Cell (1999) 6.53
A specialized vascular niche for adult neural stem cells. Cell Stem Cell (2008) 5.53
Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell (2008) 4.90
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice. J Neurosci (2004) 3.40
Metals and neuroscience. Curr Opin Chem Biol (2000) 2.14
Metals in Alzheimer's and Parkinson's diseases. Curr Opin Chem Biol (2008) 1.98
Beamline 10.3.2 at ALS: a hard X-ray microprobe for environmental and materials sciences. J Synchrotron Radiat (2004) 1.93
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Natl Acad Sci U S A (1993) 1.88
Brain barrier systems: a new frontier in metal neurotoxicological research. Toxicol Appl Pharmacol (2003) 1.55
Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy. Proc Natl Acad Sci U S A (2011) 1.40
Iron and copper toxicity in diseases of aging, particularly atherosclerosis and Alzheimer's disease. Exp Biol Med (Maywood) (2007) 1.28
The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum. J Biol Chem (2005) 1.17
Prion protein expression level alters regional copper, iron and zinc content in the mouse brain. Metallomics (2011) 1.17
Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus. Mol Neurobiol (2006) 1.11
Zinc, copper and selenium in reproduction. Experientia (1994) 1.10
Chelation therapy of manganese intoxication with para-aminosalicylic acid (PAS) in Sprague-Dawley rats. Neurotoxicology (2008) 1.09
X-ray absorption studies of yeast copper metallothionein. J Biol Chem (1988) 0.99
Hepatic copper and metallothionein distribution in Wilson's disease (hepatolenticular degeneration). Lab Invest (1987) 0.97
Brain tissue accumulates 67copper by two ligand-dependent saturable processes. A high affinity, low capacity and a low affinity, high capacity process. J Biol Chem (1988) 0.97
Copper handling by astrocytes: insights into neurodegenerative diseases. Int J Dev Neurosci (2011) 0.96
Metal imaging in neurodegenerative diseases. Metallomics (2012) 0.93
Metallothioneins are multipurpose neuroprotectants during brain pathology. FEBS J (2006) 0.92
The mitochondrial permeability transition, and oxidative and nitrosative stress in the mechanism of copper toxicity in cultured neurons and astrocytes. Lab Invest (2008) 0.91
Localization of metallothionein in the brain of rat and mouse. J Histochem Cytochem (1992) 0.91
Copper accumulation by cultured astrocytes. Neurochem Int (2009) 0.90
Copper transport and kinetics in cultured C6 rat glioma cells. Am J Physiol (1995) 0.89
Histochemical demonstration of copper in normal rat brain and spinal cord. Evidence of localization in glial cells. Histochemistry (1986) 0.87
X-ray absorption studies of the copper-beta domain of rat liver metallothionein. J Inorg Biochem (1986) 0.85
Constitutive expression of metallothionein genes in mouse brain. Toxicol Appl Pharmacol (1995) 0.82
Canine hepatic lysosomal copper protein: identification as metallothionein. Arch Biochem Biophys (1985) 0.82
Changes with age in copper and superoxide dismutase levels in brains of C57BL/6J mice. Mech Ageing Dev (1979) 0.81
Structural characterization of Cu(I) and Zn(II) sites in neuronal-growth-inhibitory factor by extended X-ray absorption fine structure (EXAFS). Eur J Biochem (1998) 0.81
Age related changes in weight and the concentrations of zinc and copper in the brain of the adult rat. Lab Anim (1990) 0.81
Age-related changes in metallothionein, copper, copper-associated protein, and lipofuscin in human liver: a histochemical and immunohistochemical study. J Pathol (1990) 0.77
Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries. Proc Natl Acad Sci U S A (2006) 9.92
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet (2009) 5.14
A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet (2010) 4.89
Influence of exercise, walking, cycling, and overall nonexercise physical activity on mortality in Chinese women. Am J Epidemiol (2007) 4.63
High-throughput screening assays for the identification of chemical probes. Nat Chem Biol (2007) 4.50
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet (2016) 4.49
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors. Cancer Res (2011) 4.22
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. Am J Physiol Endocrinol Metab (2004) 3.75
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Southern community cohort study: establishing a cohort to investigate health disparities. J Natl Med Assoc (2005) 3.67
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet (2010) 3.53
Circulating 25-hydroxyvitamin D and risk of pancreatic cancer: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol (2010) 3.51
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet (2013) 3.42
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
Protein oxidation implicated as the primary determinant of bacterial radioresistance. PLoS Biol (2007) 3.22
The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancers. Cancer Res (2010) 3.16
Soy food intake and breast cancer survival. JAMA (2009) 3.16
The landscape of recombination in African Americans. Nature (2011) 3.06
Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res (2008) 2.97
Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence. Lancet Oncol (2011) 2.85
c-Type cytochrome-dependent formation of U(IV) nanoparticles by Shewanella oneidensis. PLoS Biol (2006) 2.80
Abdominal adiposity and mortality in Chinese women. Arch Intern Med (2007) 2.75
Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays. Assay Drug Dev Technol (2004) 2.74
Vitamin D: a negative endocrine regulator of the renin-angiotensin system and blood pressure. J Steroid Biochem Mol Biol (2004) 2.73
Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome. Proc Natl Acad Sci U S A (2005) 2.72
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Effects of reproductive and demographic changes on breast cancer incidence in China: a modeling analysis. J Natl Cancer Inst (2008) 2.69
Biology of TiO2-oligonucleotide nanocomposites. Nat Mater (2003) 2.68
Identification of new genetic risk variants for type 2 diabetes. PLoS Genet (2010) 2.62
1,25-dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter. J Biol Chem (2007) 2.61
Manganese toxicity upon overexposure. NMR Biomed (2004) 2.61
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology (2012) 2.57
Night-shift work and breast cancer risk in a cohort of Chinese women. Am J Epidemiol (2010) 2.48
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
Dietary patterns and their correlates among middle-aged and elderly Chinese men: a report from the Shanghai Men's Health Study. Br J Nutr (2007) 2.35
Association of leukocyte telomere length with breast cancer risk: nested case-control findings from the Shanghai Women's Health Study. Am J Epidemiol (2013) 2.34
Chemical calcium indicators. Methods (2008) 2.33
Prospective study of dietary carbohydrates, glycemic index, glycemic load, and incidence of type 2 diabetes mellitus in middle-aged Chinese women. Arch Intern Med (2007) 2.31
Imaging of the intracellular topography of copper with a fluorescent sensor and by synchrotron x-ray fluorescence microscopy. Proc Natl Acad Sci U S A (2005) 2.30
The analysis of large-scale gene expression correlated to the phase changes of the migratory locust. Proc Natl Acad Sci U S A (2004) 2.26
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Validity and reproducibility of the food-frequency questionnaire used in the Shanghai men's health study. Br J Nutr (2007) 2.26
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. Am J Hum Genet (2013) 2.24
dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics (2010) 2.23
Manganese: recent advances in understanding its transport and neurotoxicity. Toxicol Appl Pharmacol (2007) 2.17
Compound Management for Quantitative High-Throughput Screening. JALA Charlottesv Va (2008) 2.11
VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling. Nat Cell Biol (2011) 2.09
A meta-analysis of bisphosphonates for periprosthetic bone loss after total joint arthroplasty. J Orthop Sci (2013) 2.09
Vanadium exposure-induced neurobehavioral alterations among Chinese workers. Neurotoxicology (2013) 2.08
X-ray fluorescence microprobe imaging in biology and medicine. J Cell Biochem (2006) 2.07
Ovariectomy augments hypertension in aging female Dahl salt-sensitive rats. Hypertension (2004) 2.05
An automated, broad-based, near real-time public health surveillance system using presentations to hospital Emergency Departments in New South Wales, Australia. BMC Public Health (2005) 1.99
Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium. PLoS Genet (2010) 1.98
Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor. Neurotoxicology (2007) 1.98
The choroid plexus removes beta-amyloid from brain cerebrospinal fluid. Exp Biol Med (Maywood) (2005) 1.97
Genome-wide association study of glioma and meta-analysis. Hum Genet (2012) 1.96
Circulating 25-hydroxyvitamin D and the risk of rarer cancers: Design and methods of the Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol (2010) 1.95
Reproducibility and validity of the Shanghai Women's Health Study physical activity questionnaire. Am J Epidemiol (2003) 1.95
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer. PLoS Genet (2012) 1.91
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nat Genet (2012) 1.90
Correlates of circulating 25-hydroxyvitamin D: Cohort Consortium Vitamin D Pooling Project of Rarer Cancers. Am J Epidemiol (2010) 1.90
A robotic platform for quantitative high-throughput screening. Assay Drug Dev Technol (2008) 1.90
The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90
Anthropometric measures, body mass index, and pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Arch Intern Med (2010) 1.88
Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study. Am J Clin Nutr (2008) 1.87
Cigarette smoking and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium. Am J Epidemiol (2009) 1.87
Associations of body mass index, smoking, and alcohol consumption with prostate cancer mortality in the Asia Cohort Consortium. Am J Epidemiol (2015) 1.87
Evaluation of breast cancer susceptibility loci in Chinese women. Cancer Epidemiol Biomarkers Prev (2010) 1.87
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet (2012) 1.85
Genome-wide association study identifies a common variant associated with risk of endometrial cancer. Nat Genet (2011) 1.84
Comet 81P/Wild 2 under a microscope. Science (2006) 1.83
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res (2009) 1.83
Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res (2010) 1.82
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Mechanisms of gold biomineralization in the bacterium Cupriavidus metallidurans. Proc Natl Acad Sci U S A (2009) 1.81
Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet (2012) 1.78
Intra-individual variation of plasma adipokine levels and utility of single measurement of these biomarkers in population-based studies. Cancer Epidemiol Biomarkers Prev (2007) 1.77
Elemental compositions of comet 81P/Wild 2 samples collected by Stardust. Science (2006) 1.76
Use of complementary and alternative medicine by chinese women with breast cancer. Breast Cancer Res Treat (2004) 1.76
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat Commun (2013) 1.73
Exome sequencing generates high quality data in non-target regions. BMC Genomics (2012) 1.72
Combined impact of lifestyle-related factors on total and cause-specific mortality among Chinese women: prospective cohort study. PLoS Med (2010) 1.71
Association of cyclin D1 genotype with breast cancer risk and survival. Cancer Epidemiol Biomarkers Prev (2005) 1.69
Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells. Circulation (2012) 1.69
Selenium-tolerant diamondback moth disarms hyperaccumulator plant defense. Curr Biol (2006) 1.68
Genome-wide association study of survival in patients with pancreatic adenocarcinoma. Gut (2012) 1.66
Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma. Nat Genet (2012) 1.64
Female protection in progressive renal disease is associated with estradiol attenuation of superoxide production. Gend Med (2007) 1.63
High resolution 3D x-ray diffraction microscopy. Phys Rev Lett (2002) 1.63
Zinc concentration in esophageal biopsy specimens measured by x-ray fluorescence and esophageal cancer risk. J Natl Cancer Inst (2005) 1.63