Published in Am J Hum Genet on August 01, 1990
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. I. Likelihood formulation and simulation results. Am J Hum Genet (1999) 2.88
Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles. Hum Hered (2008) 1.92
Enhanced efficiency of quantitative trait loci mapping analysis based on multivariate complexes of quantitative traits. Genetics (2001) 1.89
Use of multivariate linkage analysis for dissection of a complex cognitive trait. Am J Hum Genet (2003) 1.62
Quantitative trait locus analysis of longitudinal quantitative trait data in complex pedigrees. Genetics (2005) 1.17
Univariate/multivariate genome-wide association scans using data from families and unrelated samples. PLoS One (2009) 1.10
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. BMC Med Genet (2011) 1.06
SPReM: Sparse Projection Regression Model For High-dimensional Linear Regression. J Am Stat Assoc (2015) 1.01
Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settings. Biol Psychiatry (2008) 0.98
Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. Genetics (2001) 0.93
Projection regression models for multivariate imaging phenotype. Genet Epidemiol (2012) 0.91
Robust estimation of experimentwise P values applied to a genome scan of multiple asthma traits identifies a new region of significant linkage on chromosome 20q13. Am J Hum Genet (2005) 0.89
Multivariate dimensionality reduction approaches to identify gene-gene and gene-environment interactions underlying multiple complex traits. PLoS One (2014) 0.89
Multivariate analysis of quantitative trait loci influencing variation in anxiety-related behavior in laboratory mice. Mamm Genome (2004) 0.82
Localization of genes involved in the metabolic syndrome using multivariate linkage analysis. BMC Genet (2003) 0.80
Family-based bivariate association tests for quantitative traits. PLoS One (2009) 0.79
Design considerations in a sib-pair study of linkage for susceptibility loci in cancer. BMC Med Genet (2008) 0.78
Linkage mapping of a complex trait in the New York population of the GAW14 simulated dataset: a multivariate phenotype approach. BMC Genet (2005) 0.75
The investigation of linkage between a quantitative trait and a marker locus. Behav Genet (1972) 24.92
Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet (1990) 4.54
A more powerful robust sib-pair test of linkage for quantitative traits. Genet Epidemiol (1989) 4.17
Extensions to pedigree analysis. IV. Covariance components models for multivariate traits. Am J Med Genet (1983) 3.10
On the statistical determination of major gene mechanisms in continuous human traits: regressive models. Am J Med Genet (1984) 2.62
On the detection and estimation of linkage between a locus influencing a quantitative character and a marker locus. Biometrics (1970) 2.49
Combined linkage and segregation analysis using regressive models. Am J Hum Genet (1988) 2.33
Study of the genetic transmission of hypercholesterolemia and hypertriglyceridemia in a 195 member kindred. Ann Hum Genet (1975) 2.32
Quantitative linkage: a statistical procedure for its detection and estimation. Ann Hum Genet (1975) 2.21
Genetic analysis of von Willebrand's disease in two large pedigrees: a multivariate approach. Am J Med Genet (1980) 1.22
Assignment of the human gene for cholesteryl ester transfer protein to chromosome 16q12-16q21. Genomics (1987) 1.21
Linkage and segregation analyses of apolipoproteins A1 and B, and lipoprotein cholesterol levels in a large pedigree with excess coronary heart disease: the Bogalusa Heart Study. Genet Epidemiol (1987) 1.04
Genetics of LCAT (lecithin: cholesterol acyltransferase) deficiency. Ann Hum Genet (1975) 1.03
Bivariate analyses of cholesterol and triglyceride levels in families in which probands have type IIb lipoprotein phenotype. Am J Hum Genet (1975) 0.90
Pedigree discriminant analysis: a method to identify monogenic segregation. Am J Med Genet (1983) 0.84
Secretion of cholesteryl ester transfer protein-lipoprotein complexes by human HepG2 hepatocytes. Atherosclerosis (1989) 0.84
An approach to the multivariate analysis of high-density-lipoprotein cholesterol in a large kindred: the Bogalusa Heart Study. Genet Epidemiol (1986) 0.82
Genetic control of lecithin-cholesterol acyltransferase (LCAT): measurement of LCAT mass in a large kindred with LCAT deficiency. Am J Hum Genet (1981) 0.82
Description of a large pedigree with an adverse lipoprotein cholesterol phenotype: the Bogalusa Heart Study. Genet Epidemiol (1986) 0.81
Testing association of metric traits and marker genes. Ann Hum Genet (1959) 0.80
A comparison of some sib-pair linkage methods and multiple locus extensions. Prog Clin Biol Res (1989) 0.80
Progress toward resolving the possible linkage of multiple endocrine neoplasia type 2A to haptoglobin and group-specific loci: use of restriction fragment length polymorphisms extends exclusion region. Genet Epidemiol (1986) 0.79
A general model for the genetic analysis of pedigree data. Hum Hered (1971) 40.17
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Extensions to pedigree analysis I. Likehood calculations for simple and complex pedigrees. Hum Hered (1975) 16.67
The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics (1999) 11.20
A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidemiol (1985) 9.70
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Relationship of childhood obesity to coronary heart disease risk factors in adulthood: the Bogalusa Heart Study. Pediatrics (2001) 6.06
A unified model for complex segregation analysis. Am J Hum Genet (1983) 5.67
Biometrical genetics with one or two loci: the inheritance of physiological characters in mice. Genetics (1973) 4.38
A maximum likelihood map of chromosome 1. Am J Hum Genet (1979) 4.34
Relation of serum lipoprotein levels and systolic blood pressure to early atherosclerosis. The Bogalusa Heart Study. N Engl J Med (1986) 4.26
A more powerful robust sib-pair test of linkage for quantitative traits. Genet Epidemiol (1989) 4.17
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Oral zinc in macular degeneration. Arch Ophthalmol (1988) 3.58
Multilocus linkage tests based on affected relative pairs. Am J Hum Genet (2000) 3.57
Testing the association between polymorphic markers and quantitative traits in pedigrees. Genet Epidemiol (1987) 3.52
Bayesian analysis of haplotypes for linkage disequilibrium mapping. Genome Res (2001) 3.49
The prior probability of autosomal linkage. Ann Hum Genet (1975) 3.45
Sampling considerations in the gathering and analysis of pedigree data. Am J Hum Genet (1979) 3.32
The probabilistic determination of identity-by-descent sharing for pairs of relatives from pedigrees. Am J Hum Genet (1990) 3.30
Skewness in commingled distributions. Biometrics (1976) 3.19
Ascertainment and age of onset in pedigree analysis. Hum Hered (1973) 3.17
Essential hypertension predicted by tracking of elevated blood pressure from childhood to adulthood: the Bogalusa Heart Study. Am J Hypertens (1995) 3.07
Relatives of probands: models for preliminary genetic analysis. Ann Hum Genet (1971) 2.92
Relation of circumferences and skinfold thicknesses to lipid and insulin concentrations in children and adolescents: the Bogalusa Heart Study. Am J Clin Nutr (1999) 2.91
Robust methods for the detection of genetic linkage for quantitative data from pedigrees. Genet Epidemiol (1989) 2.78
Clinical diagnosis of the Usher syndromes. Usher Syndrome Consortium. Am J Med Genet (1994) 2.72
Evidence for mendelian inheritance in the pathogenesis of lung cancer. J Natl Cancer Inst (1990) 2.72
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Regressive logistic models for familial disease and other binary traits. Biometrics (1986) 2.70
Sex differences in the evolution of the electrocardiographic QT interval with age. Can J Cardiol (1992) 2.63
On the statistical determination of major gene mechanisms in continuous human traits: regressive models. Am J Med Genet (1984) 2.62
Efficiency and robustness of pedigree segregation analysis. Am J Hum Genet (1978) 2.60
Adolescent overweight is associated with adult overweight and related multiple cardiovascular risk factors: the Bogalusa Heart Study. Metabolism (1996) 2.60
Genetic variation of recent Alu insertions in human populations. J Mol Evol (1996) 2.56
Persistence of multiple cardiovascular risk clustering related to syndrome X from childhood to young adulthood. The Bogalusa Heart Study. Arch Intern Med (1994) 2.55
Tracking of serum lipids and lipoproteins from childhood to adulthood. The Bogalusa Heart Study. Am J Epidemiol (1991) 2.52
Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages. Am J Hum Genet (1998) 2.50
Lods, wrods, and mods: the interpretation of lod scores calculated under different models. Genet Epidemiol (1994) 2.44
Sibling correlations and segregation analysis of age-related maculopathy: the Beaver Dam Eye Study. Genet Epidemiol (1994) 2.39
Study of the genetic transmission of hypercholesterolemia and hypertriglyceridemia in a 195 member kindred. Ann Hum Genet (1975) 2.32
Body height and body mass as determinants of basal blood pressure in children--The Bogalusa Heart Study. Am J Epidemiol (1977) 2.27
Genetic epidemiology of breast cancer and associated cancers in high-risk families. I. Segregation analysis. J Natl Cancer Inst (1983) 2.21
Body fatness and risk for elevated blood pressure, total cholesterol, and serum lipoprotein ratios in children and adolescents. Am J Public Health (1992) 2.16
A faster and more general hidden Markov model algorithm for multipoint likelihood calculations. Hum Hered (1997) 2.15
Tracking of overweight status from childhood to young adulthood: the Bogalusa Heart Study. Eur J Clin Nutr (2006) 2.11
The estimation of genetic variance from twin data. Behav Genet (1970) 2.10
Confidence limits based on the first occurrence of an event. Stat Med (1993) 2.06
Multifactorial qualitative traits: genetic analysis and prediction of recurrence risks. Biometrics (1974) 2.06
General models for segregation analysis. Am J Hum Genet (1975) 2.04
Studies of blood pressures in children, ages 5-14 years, in a total biracial community: the Bogalusa Heart Study. Circulation (1976) 1.98
Variability of human linkage data. Am J Hum Genet (1978) 1.97
Longitudinal patterns of cigarette smoking and smokeless tobacco use in youth: the Bogalusa Heart Study. Am J Public Health (1986) 1.96
The Collaborative Lipid Research Clinics Family Study: biological and cultural determinants of familial resemblance for plasma lipids and lipoproteins. Genet Epidemiol (1985) 1.95
Regression toward the mean in 2 x 2 crossover designs with baseline measurements. Stat Med (1992) 1.93
Secular increases in relative weight and adiposity among children over two decades: the Bogalusa Heart Study. Pediatrics (1997) 1.91
Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. Am J Hum Genet (2001) 1.91
Localization of two genes for Usher syndrome type I to chromosome 11. Genomics (1992) 1.90
Longitudinal changes in risk variables underlying metabolic Syndrome X from childhood to young adulthood in female subjects with a history of early menarche: the Bogalusa Heart Study. Int J Obes Relat Metab Disord (2003) 1.87
Man bites dog? The validity of maximizing lod scores to determine mode of inheritance. Am J Med Genet (1989) 1.83
Probabilities of identity-by-descent patterns in sibships when the parents are not genotyped. Genet Epidemiol (1997) 1.81
A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus. Am J Hum Genet (2001) 1.80
Phenotypic variability in Friedreich ataxia: role of the associated GAA triplet repeat expansion. Ann Neurol (1997) 1.79
Multipoint linkage disequilibrium mapping with particular reference to the African-American population. Genet Epidemiol (1999) 1.78
Probability and paternity testing. Am J Hum Genet (1986) 1.75
Cigarette smoking and tobacco usage behavior in children with adolescents: Bogalusa Heart Study. Prev Med (1980) 1.75
Some capabilities for model-based and model-free linkage analysis using the program package S.A.G.E. (Statistical Analysis for Genetic Epidemiology). Hum Hered (2011) 1.73
Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule. J Gerontol A Biol Sci Med Sci (2011) 1.72
Genetic dissection of complex traits. Nat Genet (1996) 1.72
Effects of secular trends in obesity on coronary risk factors in children: the Bogalusa Heart Study. J Pediatr (1995) 1.72
Electrocardiographic prediction of abnormal genotype in congenital long QT syndrome: experience in 101 related family members. J Cardiovasc Electrophysiol (2001) 1.71
Linkage of a gene regulating dopamine-beta-hydroxylase activity and the ABO blood group locus. Am J Hum Genet (1988) 1.69
Utility of an automatic instrument for blood pressure measurement in children. The Bogalusa Heart Study. Am J Hypertens (1996) 1.68
The estimation of admixture in racial hybrids. Ann Hum Genet (1971) 1.68
Lifetime prevalence of uveal melanoma in white patients with oculo(dermal) melanocytosis. Ophthalmology (1998) 1.67
The contribution of childhood obesity to adult carotid intima-media thickness: the Bogalusa Heart Study. Int J Obes (Lond) (2008) 1.66
Effect of body size, ponderosity, and blood pressure on left ventricular growth in children and young adults in the Bogalusa Heart Study. Circulation (1995) 1.66
The interaction of cigarette smoking, oral contraceptive use, and cardiovascular risk factor variables in children: the Bogalusa Heart Study. Am J Public Health (1982) 1.65
Testing drug response in the presence of genetic information: sampling issues for clinical trials. Pharmacogenetics (2000) 1.62
Cardiovascular risk factors clustering features of insulin resistance syndrome (Syndrome X) in a biracial (Black-White) population of children, adolescents, and young adults: the Bogalusa Heart Study. Am J Epidemiol (1999) 1.61
Non-syndromic recessive auditory neuropathy is the result of mutations in the otoferlin (OTOF) gene. J Med Genet (2003) 1.60
Inheritance of adrenal phenylethanolamine N-methyltransferase activity in the rat. Genetics (1984) 1.59
An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland. Nat Genet (1996) 1.59
Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet (2000) 1.57
Persistent elevation of plasma insulin levels is associated with increased cardiovascular risk in children and young adults. The Bogalusa Heart Study. Circulation (1996) 1.54
Linkage map integration. Genomics (1996) 1.54
Inter-relationships among childhood BMI, childhood height, and adult obesity: the Bogalusa Heart Study. Int J Obes Relat Metab Disord (2004) 1.52
Extreme selection strategies in gene mapping studies of oligogenic quantitative traits do not always increase power. Hum Hered (1998) 1.52
Low birth weight and blood pressure at age 7-11 years in a biracial sample. Am J Epidemiol (1997) 1.51
A genome screen of multiplex sibships with prostate cancer. Am J Hum Genet (2000) 1.51
Major locus analysis for quantitative traits. Am J Hum Genet (1979) 1.48
Report of the committee on linkage and gene order. Cytogenet Cell Genet (1990) 1.48
Studies on blood and urine glucose in Seminole Indians: indications for segregation of a major gene. Am J Hum Genet (1974) 1.47
Cigarette smoking attitudes and first use among third- through sixth-grade students: the Bogalusa Heart Study. Am J Public Health (1997) 1.47
Use of the robust sib-pair method to screen for single-locus, multiple-locus, and pleiotropic effects: application to traits related to hypertension. Am J Hum Genet (1991) 1.45
A genome-wide search for chromosomal loci linked to mental health wellness in relatives at high risk for bipolar affective disorder among the Old Order Amish. Proc Natl Acad Sci U S A (1998) 1.45
Statistical modeling and analysis in human genetics. Annu Rev Biophys Bioeng (1978) 1.45