Published in J Biomol Screen on July 05, 2013
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Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity. J Biol Chem (2013) 1.35
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The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line. Dev Biol (2005) 1.15
Intravenous microinjections of zebrafish larvae to study acute kidney injury. J Vis Exp (2010) 1.13
Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton. PLoS Biol (2013) 1.09
Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic Acids Res (2007) 1.08
Characterization of an lhx1a transgenic reporter in zebrafish. Int J Dev Biol (2010) 1.08
Development of automated imaging and analysis for zebrafish chemical screens. J Vis Exp (2010) 1.07
Total synthesis and biological evaluation of C16 analogs of (-)-dictyostatin. J Med Chem (2007) 1.06
Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product. Chem Biol Drug Des (2006) 1.05
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Protein translocation across the inner membrane of Gram-negative bacteria: the Sec and Tat dependent protein transport pathways. Res Microbiol (2013) 1.00
Suppression of FOXQ1 in benzyl isothiocyanate-mediated inhibition of epithelial-mesenchymal transition in human breast cancer cells. Carcinogenesis (2012) 0.99
Structure-activity and high-content imaging analyses of novel tubulysins. Chem Biol Drug Des (2007) 0.98
Rapid proteomic remodeling of cardiac tissue caused by total body ionizing radiation. Proteomics (2011) 0.98
Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase. Mol Pharmacol (2004) 0.96
OCRL1 modulates cilia length in renal epithelial cells. Traffic (2012) 0.96
Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Mol Syst Biol (2011) 0.95
A high-throughput FRET-based assay for determination of Atg4 activity. Autophagy (2012) 0.94
Novel combination of mitochondrial division inhibitor 1 (mdivi-1) and platinum agents produces synergistic pro-apoptotic effect in drug resistant tumor cells. Oncotarget (2014) 0.94
Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models. Neurobiol Dis (2011) 0.94
Rhodopsin patterning in central photoreceptor cells of the blowfly Calliphora vicina: cloning and characterization of Calliphora rhodopsins Rh3, Rh5 and Rh6. J Exp Biol (2005) 0.93
A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury. Am J Physiol Renal Physiol (2013) 0.90
Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1. Bioorg Med Chem (2006) 0.90
N⁴-Phenyl-substituted 2-acetylpyridine thiosemicarbazones: cytotoxicity against human tumor cells, structure-activity relationship studies and investigation on the mechanism of action. Bioorg Med Chem (2012) 0.90
Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers. Tetrahedron (2007) 0.89
Kidney regeneration: common themes from the embryo to the adult. Pediatr Nephrol (2013) 0.89
A simplified synthesis of novel dictyostatin analogues with in vitro activity against epothilone B-resistant cells and antiangiogenic activity in zebrafish embryos. Mol Cancer Ther (2011) 0.88
Lhx1 is required for specification of the renal progenitor cell field. PLoS One (2011) 0.88
Observation of ventilation-induced Spo(2) oscillations in pigs: first step to noninvasive detection of cyclic recruitment of atelectasis? Exp Lung Res (2010) 0.88
Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryos. Chembiochem (2008) 0.87
Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1. J Pharmacol Exp Ther (2009) 0.87
A comparison of micropore membrane inlet mass spectrometry-derived pulmonary shunt measurement with Riley shunt in a porcine model. Anesth Analg (2009) 0.87
HDAC inhibitors in kidney development and disease. Pediatr Nephrol (2012) 0.86
A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling. Birth Defects Res C Embryo Today (2011) 0.86
Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin. Mol Pharmacol (2007) 0.85
Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells. Prostate (2004) 0.85
A novel player in cellular hypertrophy: Giβγ/PI3K-dependent activation of the RacGEF TIAM-1 is required for α₁-adrenoceptor induced hypertrophy in neonatal rat cardiomyocytes. J Mol Cell Cardiol (2012) 0.84
Requirement for a uroplakin 3a-like protein in the development of zebrafish pronephric tubule epithelial cell function, morphogenesis, and polarity. PLoS One (2012) 0.84
Multiple inert gas elimination technique by micropore membrane inlet mass spectrometry--a comparison with reference gas chromatography. J Appl Physiol (1985) (2013) 0.84
Evaluation of physical and mental recovery status after elective liver resection. Eur J Anaesthesiol (2009) 0.83
Influence of crystalloid and colloid fluid infusion and blood withdrawal on pulmonary bioimpedance in an animal model of mechanical ventilation. Physiol Meas (2012) 0.80
Sphingosine-1-phosphate and endothelin-1 induce the expression of rgs16 protein in cardiac myocytes by transcriptional activation of the rgs16 gene. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.79
Development and validation of a high-content bimolecular fluorescence complementation assay for small-molecule inhibitors of HIV-1 Nef dimerization. J Biomol Screen (2013) 0.79
Reduction of airspace after lung resection through controlled paralysis of the diaphragm. Eur J Cardiothorac Surg (2007) 0.78
Apical targeting and endocytosis of the sialomucin endolyn are essential for establishment of zebrafish pronephric kidney function. J Cell Sci (2012) 0.78
In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem (2014) 0.78
Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase. ChemMedChem (2015) 0.78
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors. Eur J Med Chem (2013) 0.77
Influence of fluid and volume state on PaO2 oscillations in mechanically ventilated pigs. Exp Lung Res (2013) 0.77
Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase. Org Biomol Chem (2006) 0.77
Efficient syntheses of 25,26-dihydrodictyostatin and 25,26-dihydro-6-epi-dictyostatin, two potent new microtubule-stabilizing agents. Beilstein J Org Chem (2011) 0.77
Making a tubule the noncanonical way. J Am Soc Nephrol (2011) 0.76
Gallium(III) complexes with 2-acetylpyridine-derived thiosemicarbazones: antimicrobial and cytotoxic effects and investigation on the interactions with tubulin. Biometals (2013) 0.76
Determination of respiratory gas flow by electrical impedance tomography in an animal model of mechanical ventilation. BMC Pulm Med (2014) 0.75
An unusual case of self-defense. Cell Cycle (2009) 0.75
Multi frequency phase fluorimetry (MFPF) for oxygen partial pressure measurement: ex vivo validation by polarographic clark-type electrode. PLoS One (2013) 0.75
Postoperative colonic motility after tropisetron and a standardized meal in patients undergoing conventional colorectal surgery. Int J Colorectal Dis (2006) 0.75
Total Synthesis and Biological Evaluation of Tubulysin Analogues. J Org Chem (2016) 0.75
Which Anesthesia Regimen Is Best to Reduce Morbidity and Mortality in Lung Surgery?: A Multicenter Randomized Controlled Trial. Anesthesiology (2016) 0.75
Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure. Anesth Analg (2009) 0.75
Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. Surgery (2009) 0.75