Published in Am J Ther on July 10, 2013
Activation of κ-opioid receptor by U50,488H improves vascular dysfunction in streptozotocin-induced diabetic rats. BMC Endocr Disord (2015) 0.78
Kappa Opioid Receptor Agonist and Brain Ischemia. Transl Perioper Pain Med (2014) 0.77
Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. N Engl J Med (2012) 6.17
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet (2009) 5.75
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds. N Engl J Med (2015) 5.28
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart. Nat Biotechnol (2005) 5.27
Dicer function is essential for lung epithelium morphogenesis. Proc Natl Acad Sci U S A (2006) 4.87
Dystrophin immunity in Duchenne's muscular dystrophy. N Engl J Med (2010) 4.28
Germline BAP1 mutations predispose to malignant mesothelioma. Nat Genet (2011) 4.26
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nat Genet (2012) 3.33
Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69
microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol (2010) 2.57
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells. Nat Med (2011) 2.54
Hemorrhagic fever caused by a novel Bunyavirus in China: pathogenesis and correlates of fatal outcome. Clin Infect Dis (2011) 2.34
The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals. J Infect Dis (2011) 2.26
The ecology, genetic diversity, and phylogeny of Huaiyangshan virus in China. J Virol (2011) 2.23
Electrostatic control of ions and molecules in nanofluidic transistors. Nano Lett (2005) 2.21
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. Cell (2013) 2.16
Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China. Zhonghua Liu Xing Bing Xue Za Zhi (2011) 2.15
Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer. Proc Natl Acad Sci U S A (2008) 2.06
A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet (2011) 2.05
Sleep-induced hypoxaemia in patients with chronic obstructive pulmonary disease. Br J Hosp Med (Lond) (2013) 2.04
Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Mol Ther (2011) 2.04
Controlled growth of Si nanowire arrays for device integration. Nano Lett (2005) 2.02
Human epithelial cancers secrete immunoglobulin g with unidentified specificity to promote growth and survival of tumor cells. Cancer Res (2003) 2.00
Uterine perforation in an adolescent using an intrauterine device with memory function: a case report and review of the published work. J Obstet Gynaecol Res (2014) 1.97
Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C. Nat Med (2011) 1.96
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions. Carcinogenesis (2004) 1.92
Hippocampal hypometabolism predicts cognitive decline from normal aging. Neurobiol Aging (2007) 1.90
Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. Cancer Res (2010) 1.88
Potential impact on estimated treatment effects of information lost to follow-up in randomised controlled trials (LOST-IT): systematic review. BMJ (2012) 1.85
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection. Proc Natl Acad Sci U S A (2009) 1.85
Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol (2013) 1.82
Development of enhancer trap lines for functional analysis of the rice genome. Plant J (2003) 1.81
Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis. Nat Commun (2011) 1.80
Identification of transcriptional regulators in the mouse immune system. Nat Immunol (2013) 1.79
Increased atherosclerotic lesions in apoE mice with plasma phospholipid transfer protein overexpression. Arterioscler Thromb Vasc Biol (2003) 1.79
Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling. Cancer Cell (2010) 1.78
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells. Proc Natl Acad Sci U S A (2011) 1.76
beta-Catenin promotes respiratory progenitor identity in mouse foregut. Proc Natl Acad Sci U S A (2009) 1.75
Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma. J Neurooncol (2008) 1.72
Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathog (2011) 1.72
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet (2011) 1.71
The quality of care provided to patients with cirrhosis and ascites in the Department of Veterans Affairs. Gastroenterology (2012) 1.71
Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice. Hum Gene Ther (2008) 1.65
Self-assembled TiO2-graphene hybrid nanostructures for enhanced Li-ion insertion. ACS Nano (2009) 1.64
A high-affinity monoclonal antibody to anthrax protective antigen passively protects rabbits before and after aerosolized Bacillus anthracis spore challenge. Infect Immun (2005) 1.61
Mortality and treatment outcomes of China's National Pediatric antiretroviral therapy program. Clin Infect Dis (2012) 1.61
Co-suppression of MDR1 (multidrug resistance 1) and GCS (glucosylceramide synthase) restores sensitivity to multidrug resistance breast cancer cells by RNA interference (RNAi). Cancer Biol Ther (2009) 1.56
Adeno-associated virus vector-mediated minidystrophin gene therapy improves dystrophic muscle contractile function in mdx mice. Hum Gene Ther (2002) 1.56
Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Mol Ther (2010) 1.56
An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth. Nature (2008) 1.55
Association of diet-induced hyperinsulinemia with accelerated growth of prostate cancer (LNCaP) xenografts. J Natl Cancer Inst (2007) 1.53
FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds. Dev Cell (2009) 1.53
High-resolution mapping of amplifications and deletions in pediatric osteosarcoma by use of CGH analysis of cDNA microarrays. Genes Chromosomes Cancer (2003) 1.52
Effects of biological reactions and modifications on conductance of nanofluidic channels. Nano Lett (2005) 1.50
Clinical outcome of children with newly diagnosed acute lymphoblastic leukemia treated in a single center in Shanghai, China. Leuk Lymphoma (2008) 1.49
Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophages. Infect Immun (2004) 1.47
Nanotopography influences adhesion, spreading, and self-renewal of human embryonic stem cells. ACS Nano (2012) 1.47
Nephrogenic adenoma in the augmented bladder. J Urol (2011) 1.46
A small interfering CD147-targeting RNA inhibited the proliferation, invasiveness, and metastatic activity of malignant melanoma. Cancer Res (2006) 1.46
Aurora kinase inhibitory VX-680 increases Bax/Bcl-2 ratio and induces apoptosis in Aurora-A-high acute myeloid leukemia. Blood (2007) 1.46
Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass. Cytokine (2009) 1.45
Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes (2006) 1.45
Antiarrhythmic effect mediated by κ-opioid receptor is associated with Cx43 stabilization. Crit Care Med (2010) 1.44
Multidirectional myocardial systolic function in hemodialysis patients with preserved left ventricular ejection fraction and different left ventricular geometry. Nephrol Dial Transplant (2012) 1.44
High prevalence of hepatitis B virus infection in multiple myeloma. Leuk Lymphoma (2011) 1.43
Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer. Circulation (2005) 1.42
A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes Dev (2004) 1.42
Ternary self-assembly of ordered metal oxide-graphene nanocomposites for electrochemical energy storage. ACS Nano (2010) 1.41
The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate. Amino Acids (2012) 1.41
Sequential treatment with bortezomib plus dexamethasone followed by autologous hematopoietic stem cell transplantation in patients with multiple myeloma. Chin Med J (Engl) (2012) 1.39
Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice. Proc Natl Acad Sci U S A (2009) 1.38
Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development (2011) 1.37
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy. J Cell Biol (2009) 1.36
Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev (2011) 1.36
Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy. Thromb Haemost (2011) 1.35
Recent advances in the genetics of systemic lupus erythematosus. Expert Rev Clin Immunol (2010) 1.35
Cognitive intervention for persons with mild cognitive impairment: A meta-analysis. Ageing Res Rev (2010) 1.35
Comprehensive meta-analysis of excess mortality in depression in the general community versus patients with specific illnesses. Am J Psychiatry (2014) 1.34
Age effects on the neural correlates of episodic retrieval: increased cortical recruitment with matched performance. Cereb Cortex (2007) 1.34
LOST to follow-up Information in Trials (LOST-IT): a protocol on the potential impact. Trials (2009) 1.32
MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence. PLoS One (2010) 1.31
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Hum Mol Genet (2009) 1.31
Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage. Cancer Res (2010) 1.28
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mamm Genome (2012) 1.28
Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning. Development (2005) 1.27
Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proc Natl Acad Sci U S A (2007) 1.26
Broad-spectrum matrix metalloproteinase inhibitor marimastat-induced musculoskeletal side effects in rats. Arthritis Rheum (2003) 1.26
LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease. Nat Cell Biol (2010) 1.25
One-year treatment of morpholino antisense oligomer improves skeletal and cardiac muscle functions in dystrophic mdx mice. Mol Ther (2010) 1.25
DOT1L regulates dystrophin expression and is critical for cardiac function. Genes Dev (2011) 1.25
The identification of hydroxyl groups on ZnO nanoparticles by infrared spectroscopy. Phys Chem Chem Phys (2008) 1.23
Antibody response to porcine reproductive and respiratory syndrome virus (PRRSV) nonstructural proteins and implications for diagnostic detection and differentiation of PRRSV types I and II. Clin Vaccine Immunol (2009) 1.23
Expression of immunoglobulin gene with classical V-(D)-J rearrangement in mouse brain neurons. Int J Biochem Cell Biol (2007) 1.22
Protein signaling networks from single cell fluctuations and information theory profiling. Biophys J (2011) 1.21
Hydrodynamic limb vein injection of adeno-associated virus serotype 8 vector carrying canine myostatin propeptide gene into normal dogs enhances muscle growth. Hum Gene Ther (2009) 1.21
Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant. Sci Transl Med (2013) 1.21