Published in PLoS One on June 28, 2013
Study on risk factors for severe hand, foot and mouth disease in China. PLoS One (2014) 1.13
The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model. PLoS Pathog (2015) 1.03
Toll-like receptor 9-mediated protection of enterovirus 71 infection in mice is due to the release of danger-associated molecular patterns. J Virol (2014) 0.85
Cytokine responses and correlations thereof with clinical profiles in children with enterovirus 71 infections. BMC Infect Dis (2015) 0.84
IL-6, IL-10 and IL-13 are associated with pathogenesis in children with Enterovirus 71 infection. Int J Clin Exp Med (2014) 0.83
Two models for changes of EV71 immunity in infants and young children. Hum Vaccin Immunother (2015) 0.77
Early clearance of Chikungunya virus in children is associated with a strong innate immune response. Sci Rep (2016) 0.76
Clinical and Associated Immunological Manifestations of HFMD Caused by Different Viral Infections in Children. Glob Pediatr Health (2016) 0.75
Delivery of human EV71 receptors by adeno-associated virus increases EV71 infection-induced local inflammation in adult mice. Biomed Res Int (2014) 0.75
Interleukin-27 as a Novel Biomarker for Early Cardiopulmonary Failure in Enterovirus 71-Infected Children with Central Nervous System Involvement. Mediators Inflamm (2016) 0.75
Association of interleukin-6-572C/G gene polymorphism and serum or cerebrospinal fluid interleukin-6 level with enterovirus 71 encephalitis in Chinese Han patients with hand, foot, and mouth disease. Inflammation (2015) 0.75
The immunopathogenesis of sepsis. Nature (2002) 11.83
Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol (2006) 7.56
Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. J Immunol (1983) 6.39
An apparently new enterovirus isolated from patients with disease of the central nervous system. J Infect Dis (1974) 6.22
Proinflammatory cytokines. Chest (2000) 5.89
The human hematopoietic colony-stimulating factors. Science (1987) 5.86
Neurologic complications in children with enterovirus 71 infection. N Engl J Med (1999) 5.22
Disease-associated functions of IL-33: the new kid in the IL-1 family. Nat Rev Immunol (2010) 4.92
Fulminant neurogenic pulmonary oedema with hand, foot, and mouth disease. Lancet (1998) 3.78
Enterovirus 71 infections and neurologic disease--United States, 1977-1991. J Infect Dis (1994) 3.31
Interleukin-12: biological properties and clinical application. Clin Cancer Res (2007) 3.00
Interleukin-33 - cytokine of dual function or novel alarmin? Trends Immunol (2009) 2.40
Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema. J Infect Dis (2003) 2.36
IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells. J Immunol (2002) 2.32
Do B cells drive the diversification of immune responses? Immunol Today (1993) 2.31
Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2005) 2.21
Letter: New enterovirus type associated with epidemic of aseptic meningitis and-or hand, foot, and mouth disease. Lancet (1974) 2.16
Retracted The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A (2009) 2.15
Enterovirus type 71 infections: a varied clinical pattern sometimes mimicking paralytic poliomyelitis. Rev Infect Dis (1984) 2.09
IL-23 mediates inflammatory responses to mucoid Pseudomonas aeruginosa lung infection in mice. Am J Physiol Lung Cell Mol Physiol (2006) 2.06
An evaluation of commercial fluorescent bead-based luminex cytokine assays. PLoS One (2008) 2.06
Outbreaks of hand, foot, and mouth disease by enterovirus 71. High incidence of complication disorders of central nervous system. Arch Dis Child (1980) 1.96
Deaths among children during an outbreak of hand, foot, and mouth disease--Taiwan, Republic of China, April-July 1998. MMWR Morb Mortal Wkly Rep (1998) 1.87
Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol (1996) 1.84
Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs. Infect Immun (2005) 1.65
Survey of enterovirus infections from hand, foot and mouth disease outbreak in China, 2009. Virol J (2011) 1.55
IL-33: a tissue derived cytokine pathway involved in allergic inflammation and asthma. Clin Exp Allergy (2009) 1.53
Enteroviruses as agents of emerging infectious diseases. J Neurovirol (2005) 1.51
Status of cellular rather than humoral immunity is correlated with clinical outcome of enterovirus 71. Pediatr Res (2006) 1.50
Antitumor and antimetastatic activity of IL-23. J Immunol (2003) 1.38
Enterovirus-associated encephalitis in the California encephalitis project, 1998-2005. J Infect Dis (2008) 1.34
Acute chemokine response in the blood and cerebrospinal fluid of children with enterovirus 71-associated brainstem encephalitis. J Infect Dis (2008) 1.28
Immunity to avirulent enterovirus 71 and coxsackie A16 virus protects against enterovirus 71 infection in mice. J Virol (2007) 1.16
Serum and CSF levels of MCP-1 and IP-10 in multiple sclerosis patients with acute and stable disease and undergoing immunomodulatory therapies. J Neuroimmunol (2001) 1.09
Identification of small interfering RNAs which inhibit the replication of several Enterovirus 71 strains in China. J Virol Methods (2009) 0.96
Enhanced viral immunoinflammatory lesions in mice lacking IL-23 responses. Microbes Infect (2007) 0.96
CD4 T-cell-independent antibody response reduces enterovirus 71 lethality in mice by decreasing tissue viral loads. Clin Dev Immunol (2012) 0.84
Significant elevation of B cells at the acute stage in enterovirus 71-infected children with central nervous system involvement. Scand J Infect Dis (2010) 0.80
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Genome sequence and analysis of the tuber crop potato. Nature (2011) 7.77
Depressive symptoms and health-related quality of life: the Heart and Soul Study. JAMA (2003) 7.01
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
VFDB: a reference database for bacterial virulence factors. Nucleic Acids Res (2005) 4.77
A GAL4-driver line resource for Drosophila neurobiology. Cell Rep (2012) 4.67
VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors. Nucleic Acids Res (2011) 4.36
Genetic characteristics of human enterovirus 71 and coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People's Republic of China. J Clin Microbiol (2005) 3.82
The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature (2013) 3.60
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56
Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol (2006) 3.36
R gene expression induced by a type-III effector triggers disease resistance in rice. Nature (2005) 3.25
MicroRNA-mediated control of oligodendrocyte differentiation. Neuron (2010) 3.24
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc Natl Acad Sci U S A (2003) 3.21
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol (2004) 3.19
The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. Proc Natl Acad Sci U S A (2002) 3.19
Regulation of ROS signal transduction by NADPH oxidase 4 localization. J Cell Biol (2008) 3.13
VFDB 2008 release: an enhanced web-based resource for comparative pathogenomics. Nucleic Acids Res (2007) 3.07
Enterovirus 71 outbreak in the People's Republic of China in 2008. J Clin Microbiol (2009) 2.98
OpenIGTLink: an open network protocol for image-guided therapy environment. Int J Med Robot (2009) 2.80
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet (2010) 2.68
The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2. Proc Natl Acad Sci U S A (2006) 2.63
GenomeComp: a visualization tool for microbial genome comparison. J Microbiol Methods (2003) 2.62
Analysis of wave behavior in lossy dielectric samples at high field. Magn Reson Med (2002) 2.59
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50
Genome-scale functional profiling of the mammalian AP-1 signaling pathway. Proc Natl Acad Sci U S A (2003) 2.45
Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet (2009) 2.34
TRIP8b splice variants form a family of auxiliary subunits that regulate gating and trafficking of HCN channels in the brain. Neuron (2009) 2.30
Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer. Cancer Res (2010) 2.27
Virome analysis for identification of novel mammalian viruses in bat species from Chinese provinces. J Virol (2012) 2.21
Human cytomegalovirus escapes a naturally occurring neutralizing antibody by incorporating it into assembling virions. Cell Host Microbe (2011) 2.20
d+id' chiral superconductivity in bilayer silicene. Phys Rev Lett (2013) 2.18
Testing the position-effect variegation hypothesis for facioscapulohumeral muscular dystrophy by analysis of histone modification and gene expression in subtelomeric 4q. Hum Mol Genet (2003) 2.15
The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics. Nat Immunol (2007) 2.13
CD4+CD25+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J Immunol (2003) 2.11
c-Maf regulates IL-10 expression during Th17 polarization. J Immunol (2009) 1.99
Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses. PLoS Pathog (2013) 1.99
Transcriptional adaptation of Shigella flexneri during infection of macrophages and epithelial cells: insights into the strategies of a cytosolic bacterial pathogen. Infect Immun (2005) 1.96
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance. Circ Res (2006) 1.95
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development (2005) 1.93
An essential role for stromal interaction molecule 1 in neointima formation following arterial injury. Cardiovasc Res (2008) 1.87
GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers. PLoS Genet (2012) 1.86
Derivation of human embryonic stem cell lines from parthenogenetic blastocysts. Cell Res (2007) 1.83
miR-146a controls the resolution of T cell responses in mice. J Exp Med (2012) 1.81
Mitogen-activated protein kinases mediate upregulation of hypothalamic angiotensin II type 1 receptors in heart failure rats. Hypertension (2008) 1.78
Acid rain in China. Environ Sci Technol (2006) 1.75
RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects. Breast Cancer Res Treat (2010) 1.74
Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer. Cancer Res (2010) 1.74
The WUSCHEL-related homeobox gene WOX11 is required to activate shoot-borne crown root development in rice. Plant Cell (2009) 1.74
Imatinib (ST1571) provides only limited selectivity for CML cells and treatment might be complicated by silent BCR-ABL genes. Cancer Biol Ther (2003) 1.73
Complete genome analysis of coxsackievirus A2, A4, A5, and A10 strains isolated from hand, foot, and mouth disease patients in China revealing frequent recombination of human enterovirus A. J Clin Microbiol (2011) 1.71
SLC11A1 (NRAMP1) polymorphisms and tuberculosis susceptibility: updated systematic review and meta-analysis. PLoS One (2011) 1.70
Polymorphisms of tumor necrosis factor-alpha and breast cancer risk: a meta-analysis. Breast Cancer Res Treat (2010) 1.70
Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties. J Gen Physiol (2007) 1.68
MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720. Clin Cancer Res (2010) 1.68
The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein. J Biol Chem (2011) 1.68
Influenza H7N9 and H9N2 viruses: coexistence in poultry linked to human H7N9 infection and genome characteristics. J Virol (2014) 1.67
The 3C protein of enterovirus 71 inhibits retinoid acid-inducible gene I-mediated interferon regulatory factor 3 activation and type I interferon responses. J Virol (2010) 1.66
Mach-Zehnder interferometry in a strongly driven superconducting qubit. Science (2005) 1.65
Region-specific alternative splicing in the nervous system: implications for regulation by the RNA-binding protein NAPOR. RNA (2002) 1.65
Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. J Immunol (2005) 1.64
Genes that escape from X inactivation. Hum Genet (2011) 1.63
Lipid interaction converts prion protein to a PrPSc-like proteinase K-resistant conformation under physiological conditions. Biochemistry (2007) 1.62
Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3. J Virol (2011) 1.61
A Xanthomonas uridine 5'-monophosphate transferase inhibits plant immune kinases. Nature (2012) 1.60
Complete sequence of a novel 178-kilobase plasmid carrying bla(NDM-1) in a Providencia stuartii strain isolated in Afghanistan. Antimicrob Agents Chemother (2012) 1.60
Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood (2002) 1.59
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. Genomics (2007) 1.59
Multiple organ infection and the pathogenesis of SARS. J Exp Med (2005) 1.58
Human rhinoviruses in Chinese adults with acute respiratory tract infection. J Infect (2010) 1.58
Video-assisted thoracoscopic left cardiac sympathetic denervation: a reliable minimally invasive approach for congenital long-QT syndrome. Ann Thorac Surg (2008) 1.58
Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem (2009) 1.56
Segmental instability in cervical spondylotic myelopathy with severe disc degeneration. Spine (Phila Pa 1976) (2006) 1.56
Monocytic suppressive cells mediate cardiovascular transplantation tolerance in mice. J Clin Invest (2010) 1.55
Survey of enterovirus infections from hand, foot and mouth disease outbreak in China, 2009. Virol J (2011) 1.55
Hierarchical MnMoO(4)/CoMoO(4) heterostructured nanowires with enhanced supercapacitor performance. Nat Commun (2011) 1.55
Revisiting the molecular evolutionary history of Shigella spp. J Mol Evol (2006) 1.54
Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics (2006) 1.54
Reduced Th17 response in patients with tuberculosis correlates with IL-6R expression on CD4+ T Cells. Am J Respir Crit Care Med (2009) 1.54
mGRASP enables mapping mammalian synaptic connectivity with light microscopy. Nat Methods (2011) 1.53
The future of biologic coatings for orthopaedic implants. Biomaterials (2013) 1.53
Tumor-derived CD4(+)CD25(+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10. Cancer Immunol Immunother (2006) 1.53
DJ-1 may contribute to metastasis of non-small cell lung cancer. Mol Biol Rep (2011) 1.52
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arterioscler Thromb Vasc Biol (2005) 1.52