Published in J Biol Chem on July 18, 2013
M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7. Proc Natl Acad Sci U S A (2014) 1.35
Pancreatic duct cells as a source of VEGF in mice. Diabetologia (2014) 1.03
Pancreatic cell tracing, lineage tagging and targeted genetic manipulations in multiple cell types using pancreatic ductal infusion of adeno-associated viral vectors and/or cell-tagging dyes. Nat Protoc (2014) 0.93
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Pancreatic duct ligation after almost complete β-cell loss: exocrine regeneration but no evidence of β-cell regeneration. Endocrinology (2013) 0.88
Proliferating pancreatic beta-cells upregulate ALDH. Histochem Cell Biol (2014) 0.81
ALDH expression characterizes G1-phase proliferating beta cells during pregnancy. PLoS One (2014) 0.81
Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate. PLoS One (2015) 0.81
Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice. Sci Rep (2015) 0.79
PNA lectin for purifying mouse acinar cells from the inflamed pancreas. Sci Rep (2016) 0.79
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FoxO1 inhibits accelerated β-cell aging in pancreas-specific SMAD7 mutant mice. J Biol Chem (2017) 0.78
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Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas. Cell Commun Signal (2016) 0.75
Epidermal Growth Factor Receptor Signaling Regulates β Cell Proliferation in Adult Mice. J Biol Chem (2016) 0.75
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SMAD3/Stat3 Signaling Mediates β-Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes. Diabetes (2017) 0.75
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature (2004) 16.56
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development (2002) 12.21
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell (2008) 8.57
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet (2010) 6.81
Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes (2008) 5.23
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest (2001) 4.93
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Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development (2000) 4.71
Very slow turnover of beta-cells in aged adult mice. Diabetes (2005) 4.54
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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J Clin Invest (2002) 4.05
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A (2008) 4.01
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell (2009) 3.63
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation. Diabetes (2000) 3.46
Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes (2009) 3.45
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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development (2011) 3.11
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Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest (2007) 2.92
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Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types. Dev Biol (2004) 2.68
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Epigenomic plasticity enables human pancreatic α to β cell reprogramming. J Clin Invest (2013) 2.38
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A (2009) 2.09
Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion. J Cell Biol (1985) 2.00
Human β-cell proliferation and intracellular signaling: driving in the dark without a road map. Diabetes (2012) 1.97
Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas. Development (2011) 1.89
The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation. Diabetologia (2009) 1.87
Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration. Development (2013) 1.83
Lineage tracing evidence for in vitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells. Diabetes (2007) 1.78
Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. J Clin Invest (2006) 1.74
Minireview: Meeting the demand for insulin: molecular mechanisms of adaptive postnatal beta-cell mass expansion. Mol Endocrinol (2009) 1.72
FoxOs function synergistically to promote glucose production. J Biol Chem (2010) 1.66
Apoptosis differently affects lineage tracing of Lgr5 and Bmi1 intestinal stem cell populations. Cell Stem Cell (2013) 1.66
No evidence for β cell neogenesis in murine adult pancreas. J Clin Invest (2013) 1.54
Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice. PLoS One (2012) 1.50
The role of aging upon β cell turnover. J Clin Invest (2013) 1.50
Notch signalling suppresses apoptosis in adult human and mouse pancreatic islet cells. Diabetologia (2007) 1.49
Beta-cell proliferation, but not neogenesis, following 60% partial pancreatectomy is impaired in the absence of FoxM1. Diabetes (2008) 1.46
MafA and MafB activity in pancreatic β cells. Trends Endocrinol Metab (2011) 1.44
Ductal origin hypothesis of pancreatic regeneration under attack. Cell Metab (2010) 1.41
Robust acinar cell transgene expression of CreErT via BAC recombineering. Genesis (2008) 1.30
β-Cells are not generated in pancreatic duct ligation-induced injury in adult mice. Diabetes (2013) 1.22
TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation. Diabetes (2012) 1.21
Adult pancreatic acinar cells give rise to ducts but not endocrine cells in response to growth factor signaling. Development (2010) 1.21
Progenitor cell domains in the developing and adult pancreas. Cell Cycle (2011) 1.20
Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice. Biochem Biophys Res Commun (2005) 1.13
Tamoxifen-independent recombination in the RIP-CreER mouse. PLoS One (2010) 1.12
Pancreatic beta cells in very old mice retain capacity for compensatory proliferation. J Biol Chem (2012) 1.09
Hypoglycemia reduces vascular endothelial growth factor A production by pancreatic beta cells as a regulator of beta cell mass. J Biol Chem (2013) 1.06
Beta cells within single human islets originate from multiple progenitors. PLoS One (2008) 1.05
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. Stem Cell Res (2013) 0.95
A view on beta cell transplantation in diabetes. Ann N Y Acad Sci (2002) 0.94
Beta cell count instead of beta cell mass to assess and localize growth in beta cell population following pancreatic duct ligation in mice. PLoS One (2012) 0.94
Streptozotocin-induced expression of Ngn3 and Pax4 in neonatal rat pancreatic α-cells. World J Gastroenterol (2011) 0.86
Local in vivo GSK3β knockdown promotes pancreatic β cell and acinar cell regeneration in 90% pancreatectomized rat. Mol Ther (2012) 0.80
Beta cell transplantation and immunosuppression: can't live with it, can't live without it. J Clin Invest (2007) 0.78
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication. Kidney Int (2004) 2.17
Necrotizing enterocolitis in full-term infants. J Pediatr Surg (2003) 1.85
Reciprocal expression and signaling of TLR4 and TLR9 in the pathogenesis and treatment of necrotizing enterocolitis. J Immunol (2009) 1.83
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc Natl Acad Sci U S A (2003) 1.79
Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathway. Cancer Res (2007) 1.68
Intestinal epithelial Toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice. Gastroenterology (2012) 1.59
Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res (2006) 1.55
No evidence for β cell neogenesis in murine adult pancreas. J Clin Invest (2013) 1.54
Molecular epidemiology of clinical isolates of carbapenem-resistant Acinetobacter spp. from Chinese hospitals. Antimicrob Agents Chemother (2007) 1.49
Impact of angiogenesis inhibition by sunitinib on tumor distribution of temozolomide. Clin Cancer Res (2008) 1.41
The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. Diabetes (2002) 1.35
Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice. Gastroenterology (2011) 1.35
M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7. Proc Natl Acad Sci U S A (2014) 1.35
Renal effects of Tamm-Horsfall protein (uromodulin) deficiency in mice. Am J Physiol Renal Physiol (2004) 1.32
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Mol Endocrinol (2007) 1.28
Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium. Proc Natl Acad Sci U S A (2012) 1.24
TGFβ receptor signaling is essential for inflammation-induced but not β-cell workload-induced β-cell proliferation. Diabetes (2012) 1.21
Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing regimens in EGFR wild-type and mutant tumor models. Mol Cancer Ther (2008) 1.20
The effect of P-glycoprotein on paclitaxel brain and brain tumor distribution in mice. Cancer Res (2003) 1.18
Embryonic mouse blood flow and oxygen correlate with early pancreatic differentiation. Dev Biol (2010) 1.17
Dysregulation of the norepinephrine transporter sustains cortical hypodopaminergia and schizophrenia-like behaviors in neuronal rictor null mice. PLoS Biol (2010) 1.16
Increased PDX-1 expression is associated with outcome in patients with pancreatic cancer. Surgery (2003) 1.14
Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas. Diabetes (2002) 1.13
Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition. Clin Cancer Res (2007) 1.10
A smad signaling network regulates islet cell proliferation. Diabetes (2013) 1.08
Downregulation of miR-223 and miR-153 mediates mechanical stretch-stimulated proliferation of venous smooth muscle cells via activation of the insulin-like growth factor-1 receptor. Arch Biochem Biophys (2012) 1.06
Lectin as a marker for staining and purification of embryonic pancreatic epithelium. Biochem Biophys Res Commun (2002) 1.06
TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol (2007) 1.06
Hypoglycemia reduces vascular endothelial growth factor A production by pancreatic beta cells as a regulator of beta cell mass. J Biol Chem (2013) 1.06
Estradiol and nicotine exposure enhances A549 bronchioloalveolar carcinoma xenograft growth in mice through the stimulation of angiogenesis. Int J Oncol (2006) 1.05
Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage. Cancer Res (2007) 1.04
Cross-talk between bone morphogenetic protein and transforming growth factor-beta signaling is essential for exendin-4-induced insulin-positive differentiation of AR42J cells. J Biol Chem (2005) 1.04
Minimally invasive congenital diaphragmatic hernia repair: a 7-year review of one institution's experience. Surg Endosc (2008) 1.04
Pancreatic duct cells as a source of VEGF in mice. Diabetologia (2014) 1.03
The formation of daodi medicinal materials. J Ethnopharmacol (2012) 1.01
Pharmacodynamic-mediated effects of the angiogenesis inhibitor SU5416 on the tumor disposition of temozolomide in subcutaneous and intracerebral glioma xenograft models. J Pharmacol Exp Ther (2003) 1.01
Multifaceted pancreatic mesenchymal control of epithelial lineage selection. Dev Biol (2004) 1.00
An effective pyloromyotomy length in infants undergoing laparoscopic pyloromyotomy. Surgery (2004) 0.99
Management of postoperative infections after the minimally invasive pectus excavatum repair. J Pediatr Surg (2005) 0.99
Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis. J Biol Chem (2014) 0.98
Rapid and simplified purification of recombinant adeno-associated virus. J Virol Methods (2012) 0.98
A new Tn1546 type of VanB phenotype-vanA genotype vancomycin-resistant Enterococcus faecium isolates in mainland China. Diagn Microbiol Infect Dis (2009) 0.97
Pharmacokinetic model-predicted anticancer drug concentrations in human tumors. Clin Cancer Res (2004) 0.97
Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence. Biochem J (2008) 0.97
Pancreatic epithelial cells can be converted into insulin-producing cells by GLP-1 in conjunction with virus-mediated gene transfer of pdx-1. Surgery (2005) 0.96
Effects of four Si-Wu-Tang's constituents and their combination on irradiated mice. Biol Pharm Bull (2006) 0.96
Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin. Cancer Res (2002) 0.96
Urachal anomalies in children: the vanishing relevance of the preoperative voiding cystourethrogram. J Pediatr Surg (2005) 0.95
Maternal microchimerism in biliary atresia. J Pediatr Surg (2007) 0.95
Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens. J Pharmacol Exp Ther (2007) 0.94
Washout of heme-containing proteins dramatically improves tetrazolium-based infarct staining. J Pharmacol Toxicol Methods (2006) 0.93
Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions. Gastroenterology (2002) 0.93
Smad signaling pathways regulate pancreatic endocrine development. Dev Biol (2013) 0.93