Published in Proc Natl Acad Sci U S A on August 19, 2013
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The Neural Cell Adhesion Molecule NCAM Promotes Clustering and Activation of EphA3 Receptors in GABAergic Interneurons to Induce RhoA/ROCK-mediated Growth Cone Collapse. J Biol Chem (2016) 0.75
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Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron (2005) 1.44
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Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity. J Biol Chem (2009) 1.19
Excitatory Eph receptors and adhesive ephrin ligands. Curr Opin Cell Biol (2001) 1.17
Concepts and consequences of Eph receptor clustering. Semin Cell Dev Biol (2012) 1.13
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Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor. Biochem J (2009) 1.06
Immunocompetent mouse model of breast cancer for preclinical testing of EphA2-targeted therapy. Cancer Gene Ther (2005) 0.95
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations. Biochem Biophys Res Commun (2010) 0.92
The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nat Med (2007) 5.06
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol (2007) 5.02
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling. Nat Neurosci (2004) 4.22
An optical AC voltage sensor based on the transverse Pockels effect. Sensors (Basel) (2011) 4.08
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell (2003) 3.68
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell (2005) 3.34
Distinct α-synuclein strains differentially promote tau inclusions in neurons. Cell (2013) 3.24
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway. Nat Immunol (2004) 2.86
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma. Cell (2011) 2.83
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol (2009) 2.76
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity. Nat Immunol (2013) 2.64
Preparation and evaluation of recombinant severe fever with thrombocytopenia syndrome virus nucleocapsid protein for detection of total antibodies in human and animal sera by double-antigen sandwich enzyme-linked immunosorbent assay. J Clin Microbiol (2011) 2.63
Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. J Biol Chem (2009) 2.60
Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. J Clin Invest (2011) 2.58
Facilitation of resident scholarly activity: strategy and outcome analyses using historical resident cohorts and a rank-to-match population. Anesthesiology (2014) 2.52
Helicase-dependent isothermal DNA amplification. EMBO Rep (2004) 2.51
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol (2008) 2.41
IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART. J Clin Invest (2005) 2.41
Effect of ocean acidification on iron availability to marine phytoplankton. Science (2010) 2.37
Prognostic significance of microscopic positive margins for gastric cancer patients with potentially curative resection. Ann Surg Oncol (2009) 2.31
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. J Clin Invest (2009) 2.28
Cell-cell signaling via Eph receptors and ephrins. Curr Opin Cell Biol (2007) 2.24
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis. J Biol Chem (2005) 2.15
Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine. J Virol (2002) 2.13
Adverse events over two years after retropubic or transobturator midurethral sling surgery: findings from the Trial of Midurethral Slings (TOMUS) study. Am J Obstet Gynecol (2011) 2.09
A neutralizing human monoclonal antibody protects against lethal disease in a new ferret model of acute nipah virus infection. PLoS Pathog (2009) 2.09
Host cell recognition by the henipaviruses: crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc Natl Acad Sci U S A (2008) 2.08
Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metab (2011) 2.08
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene (2005) 2.07
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Sci Signal (2010) 2.04
Exploring the role of a conserved class A residue in the Ω-Loop of KPC-2 β-lactamase: a mechanism for ceftazidime hydrolysis. J Biol Chem (2012) 1.93
Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. Am J Physiol Lung Cell Mol Physiol (2005) 1.93
Intensification and stimulation therapy for human immunodeficiency virus type 1 reservoirs in infected persons receiving virally suppressive highly active antiretroviral therapy. J Infect Dis (2002) 1.91
Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. Acta Neuropathol (2007) 1.91
Lysophospholipids are potential biomarkers of ovarian cancer. Cancer Epidemiol Biomarkers Prev (2004) 1.87
Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation. Am J Respir Crit Care Med (2011) 1.84
Architecture of Eph receptor clusters. Proc Natl Acad Sci U S A (2010) 1.82
Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J (2003) 1.78
Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis. J Exp Med (2012) 1.76
Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung. Dev Dyn (2004) 1.75
TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression. J Biol Chem (2003) 1.75
Eph signaling: a structural view. Trends Neurosci (2003) 1.74
En face view of atrial septal defect by two-dimensional transthoracic echocardiography: comparison to real-time three-dimensional transesophageal echocardiography. J Am Soc Echocardiogr (2010) 1.71
Bone marrow stromal cells protect myeloma cells from bortezomib induced apoptosis by suppressing microRNA-15a expression. Leuk Lymphoma (2011) 1.70
Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia. Nat Chem Biol (2011) 1.70
Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung. Am J Physiol Lung Cell Mol Physiol (2003) 1.68
Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding. Neuron (2002) 1.66
C/EBPalpha is required for lung maturation at birth. Development (2006) 1.65
Structure of the semaphorin-3A receptor binding module. Neuron (2003) 1.63
Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells. J Biol Chem (2006) 1.58
Foxa2 is required for transition to air breathing at birth. Proc Natl Acad Sci U S A (2004) 1.57
Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr. EMBO J (2002) 1.56
Abnormalities in osteoclastogenesis and decreased tumorigenesis in mice deficient for ovarian cancer G protein-coupled receptor 1. PLoS One (2009) 1.55
Development of an acute and highly pathogenic nonhuman primate model of Nipah virus infection. PLoS One (2010) 1.54
A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation. Chem Biol (2011) 1.54
Macroscopic serosal classification predicts peritoneal recurrence for patients with gastric cancer underwent potentially curative surgery. Ann Surg Oncol (2010) 1.52
Use of a problem-based learning discussion format to teach anesthesiology residents research fundamentals. J Clin Anesth (2013) 1.50
Quality of life in women with stress urinary incontinence. Int Urogynecol J Pelvic Floor Dysfunct (2006) 1.49
Common genetic variants on 5p15.33 contribute to risk of lung adenocarcinoma in a Chinese population. Carcinogenesis (2009) 1.48
Clinical and demographic factors associated with valsalva leak point pressure among women undergoing burch bladder neck suspension or autologous rectus fascial sling procedures. Neurourol Urodyn (2007) 1.47
Log odds of positive lymph nodes: a novel prognostic indicator superior to the number-based and the ratio-based N category for gastric cancer patients with R0 resection. Cancer (2010) 1.46
Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells and enhances adhesion, migration, and invasion of ovarian cancer cells. Cancer Res (2006) 1.45
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol Biol Cell (2008) 1.44
MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth. Cancer Lett (2013) 1.44
Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. EMBO Rep (2009) 1.42
Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C. J Cell Biol (2006) 1.41
Tie1-Tie2 interactions mediate functional differences between angiopoietin ligands. Mol Cell (2010) 1.39
A recombinant Hendra virus G glycoprotein-based subunit vaccine protects ferrets from lethal Hendra virus challenge. Vaccine (2011) 1.39
Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon. Oncogene (2002) 1.39
Predictors of radiographic knee osteoarthritis after anterior cruciate ligament reconstruction. Am J Sports Med (2011) 1.39
Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung. J Clin Invest (2012) 1.36
Synthesis, magnetic anisotropy and optical properties of preferred oriented zinc ferrite nanowire arrays. Nanoscale Res Lett (2010) 1.36
Kruppel-like factor 5 is required for perinatal lung morphogenesis and function. Development (2008) 1.35
A neutralizing human monoclonal antibody protects african green monkeys from hendra virus challenge. Sci Transl Med (2011) 1.35
Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J Clin Invest (2006) 1.33
KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha. Clin Exp Metastasis (2005) 1.33
Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex. Nat Struct Mol Biol (2006) 1.31
Plasma lysophosphatidylcholine levels: potential biomarkers for colorectal cancer. J Clin Oncol (2007) 1.30
Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. Proc Natl Acad Sci U S A (2002) 1.29
Hypoxia enhances lysophosphatidic acid responsiveness in ovarian cancer cells and lysophosphatidic acid induces ovarian tumor metastasis in vivo. Cancer Res (2006) 1.29
DNA/MVA vaccine for HIV type 1: effects of codon-optimization and the expression of aggregates or virus-like particles on the immunogenicity of the DNA prime. AIDS Res Hum Retroviruses (2004) 1.27
The cumate gene-switch: a system for regulated expression in mammalian cells. BMC Biotechnol (2006) 1.26
Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC. Protein Sci (2003) 1.26
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine. Nat Commun (2012) 1.26
Volumetric topological analysis: a novel approach for trabecular bone classification on the continuum between plates and rods. IEEE Trans Med Imaging (2010) 1.25
Inhibition of long non-coding RNA NEAT1 impairs myeloid differentiation in acute promyelocytic leukemia cells. BMC Cancer (2014) 1.23
An extremely simple method for extraction of lysophospholipids and phospholipids from blood samples. J Lipid Res (2009) 1.23
A novel raw starch digesting alpha-amylase from a newly isolated Bacillus sp. YX-1: purification and characterization. Bioresour Technol (2007) 1.22
Transient expression of glyoxal oxidase from the Chinese wild grape Vitis pseudoreticulata can suppress powdery mildew in a susceptible genotype. Protoplasma (2010) 1.22
Expression of ABCA3 in developing lung and other tissues. J Histochem Cytochem (2006) 1.21
Artificial neural networks distinguish among subtypes of neoplastic colorectal lesions. Gastroenterology (2002) 1.21